We narrowed to 1,213 results for: Aspa

1. pDEST40-Arl13b89

   Plasmid

   #40874

   Depositor

   Tamara Caspary

   Article

   Larkins et al Mol Biol Cell. 2011 Dec;22(23):4694-703.

   Insert

   Arl13b (Arl13b Mouse)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   CMV

   Available since

   Oct. 29, 2012

   Availability

   Academic Institutions and Nonprofits only

   

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2. pTYF-sGFAP-LOx-IRES-tdTomato

   Plasmid

   #166919

   Purpose

   Express the bacterial lactate oxidase (LOx) enzyme in astrocytes

   Depositor

   Sergey Kasparov

   Article

   Vaccari Cardoso et al Glia. 2021 Jan 5. doi: 10.1002/glia.2396

   Insert

   Lactate oxidase
   

   Use

   Lentiviral

   Tags

   tdTomato

   Expression

   Mammalian

   Mutation

   Promoter

   sGFAP

   Available since

   April 23, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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3. pTYF-1xGfaABC1D-tTA

   Plasmid

   #19977

   Depositor

   Sergey Kasparov

   Article

   Liu et al J Gene Med. 2008 May . 10(5):583-92.

   Insert

   GfaABC1D-tTA (GFAP E.coli, Human)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   Aug. 5, 2009

   Availability

   Academic Institutions and Nonprofits only

   

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4. pYihI-N-term D-A/E-L

   Plasmid

   #233097

   Purpose

   Expression of GST-YihI with N-term aspartic acids (D) mutated to alanine (A) and glutamic acids (E) mutated to leucine (L)

   Depositor

   Michael Downey

   Article

   Baijal et al bioRxiv 2025.02.12.637445

   Insert

   YihI with N-term aspartic acids (D) mutated to alanine (A) and glutamic acids (E) mutated to leucine (L)
   

   Use

   Tags

   GST

   Expression

   Bacterial

   Mutation

   N-term aspartic acids (D) mutated to alanine (A) …

   Promoter

   Available since

   May 7, 2025

   Availability

   Industry, Academic Institutions, and Nonprofits

   

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5. DsRed-Rab5 DN

   Plasmid

   #13051

   Depositor

   Richard Pagano

   Article

   Sharma et al J Biol Chem. 2003 Feb 28. 278(9):7564-72

   Insert

   RAB5A (Canis familiaris) (RAB5A Canis familiaris)
   

   Use

   Tags

   DsRed2 and HA

   Expression

   Mammalian

   Mutation

   asparagine 3 changed to serine (neutral); aspara…

   Promoter

   Available since

   Oct. 16, 2006

   Availability

   Academic Institutions and Nonprofits only

   

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6. AAV GFP

   Plasmid

   #49055

   Purpose

   adeno-associated virus (AAV) encoding a green fluorescent protein

   Depositor

   Fred Gage

   Article

   Kaspar et al Proc Natl Acad Sci U S A. 2002 Feb 19;99

   Insert

   eGFP
   

   Use

   AAV

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   CMV

   Available since

   Feb. 7, 2014

   Availability

   Academic Institutions and Nonprofits only

   

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7. pSicoR-mCh-empty

   Plasmid

   #21907

   Purpose

   Cre-regulated lentiviral shRNA vector. Cre addition causes both mCherry and shRNA to be recombined out of the construct, turning OFF shRNA expression.

   Depositor

   Miguel Ramalho-Santos

   Article

   Gaspar-Maia et al Nature. 2009 Aug 13;460(7257):863-8. doi

   Type

   Empty backbone

   Use

   Lentiviral and RNAi

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   Sept. 30, 2009

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

8. pDEST47-Arl13b17

   Plasmid

   #40875

   Depositor

   Tamara Caspary

   Article

   Larkins et al Mol Biol Cell. 2011 Dec;22(23):4694-703.

   Insert

   Arl13b (Arl13b Mouse)
   

   Use

   Tags

   GFP

   Expression

   Mammalian

   Mutation

   contains Arl13b amino acids 1-199

   Promoter

   CMV

   Available since

   March 13, 2013

   Availability

   Academic Institutions and Nonprofits only

9. Delta DED FLIP-L D/A

   Plasmid

   #13791

   Depositor

   Guy Salvesen

   Article

   Boatright et al Biochem J. 2004 Sep 1. 382(Pt 2):651-7.

   Insert

   DELTA DED FLIP LONG (CFLAR Human)
   

   Use

   Tags

   8 x His tag

   Expression

   Bacterial

   Mutation

   Delta DED removes first 186 residues Asp to Ala m…

   Promoter

   Available since

   Jan. 25, 2007

   Availability

   Academic Institutions and Nonprofits only

   

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10. pLL3.7-Casp2-shRNA

    Plasmid

    #157926

    Purpose

    Knockdown of caspase-2

    Depositor

    Baoji Xu

    Article

    Xu et al Nat Commun. 2019 Aug 9;10(1):3622. doi:

    Insert

    Casp2 shRNA (Casp2 Mouse)
    

    Use

    Lentiviral and RNAi

    Tags

    GFP

    Expression

    Mutation

    Promoter

    mouse U6

    Available since

    Sept. 10, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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11. pDEST53-Arl13b20

    Plasmid

    #40876

    Depositor

    Tamara Caspary

    Article

    Larkins et al Mol Biol Cell. 2011 Dec;22(23):4694-703.

    Insert

    Arl13b (Arl13b Mouse)
    

    Use

    Tags

    GFP

    Expression

    Mammalian

    Mutation

    deleted Arl N-terminal domain; added stop codon

    Promoter

    CMV

    Available since

    Nov. 29, 2012

    Availability

    Academic Institutions and Nonprofits only

12. PB-mCar-EGFP-WPRE-BGH-pA-UBC-Bla

    Plasmid

    #174620

    Purpose

    PiggyBac plasmid expressing EGFP under the control of a cone arrestin promoter

    Depositor

    Volker Busskamp

    Article

    Gasparini et al J Clin Invest. 2022 Apr 28. pii: 154619.

    Insert

    enhanced green fluorescent protein
    

    Use

    Piggybac

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Nov. 30, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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13. pEGFP/golgin-160/3DE

    Plasmid

    #180631

    Purpose

    Expression of caspase-resistant golgin-160

    Depositor

    Carolyn Machamer

    Article

    Mancini et al J Cell Biol. 2000 May 1;149(3):603-12. d

    Insert

    golgin-160/3DE (GOLGA3 Human)
    

    Use

    Tags

    EGFP

    Expression

    Mammalian

    Mutation

    D59E, D139E, D311E

    Promoter

    Available since

    March 24, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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14. GFP-DroshaS302D

    Plasmid

    #62529

    Purpose

    Serine 302 of Drosha is mutated to aspartic acid

    Depositor

    Bharat Ramratnam

    Article

    Tang et al Nucleic Acids Res. 2010 Oct;38(19):6610-

    Insert

    human Drosha with serine 302 changed to aspartic acid (DROSHA Human)
    

    Use

    Tags

    GFP

    Expression

    Mammalian

    Mutation

    changed serine 302 to aspartic acid

    Promoter

    Available since

    March 20, 2015

    Availability

    Academic Institutions and Nonprofits only

15. pCMMP-MCS-IRES-eGFP-P2A-iCas9

    Plasmid

    #178533

    Purpose

    For genome editing: EGFP-inducible Caspase9 knock-in cassette which allows ablation of target cells

    Depositor

    Ryoji Yao

    Article

    Okamoto et al STAR Protoc. 2021 Sep 16;2(4):100780. do

    Insert

    iCaspase9 (CASP9 Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    FKBP12 F36 to V Truncated Caspase9 (135-416; lack…

    Promoter

    Available since

    Jan. 13, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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16. N-terminal 3X Flag Human CASP9 C287A Mutant

    Plasmid

    #198380

    Purpose

    Expresses Human N-Terminal 3X Flag CASP9 Catalytic Mutant in Mammalian Cells

    Depositor

    Hannah Rabinowich

    Article

    Han et al Autophagy. 2021 Jun;17(6):1393-1409. doi

    Insert

    N-Terminal 3X Flag Human Caspase-9 C287A Mutant (CASP9 Human)
    

    Use

    Tags

    3X Flag

    Expression

    Mammalian

    Mutation

    Changed Cysteine 287 to Alanine to eliminate prot…

    Promoter

    CMV

    Available since

    April 14, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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17. AAV-GFP/Cre

    Plasmid

    #49056

    Purpose

    Adeno-associated virus (AAV) encoding a green fluorescent protein/Cre recombinase (GFP/Cre) fusion protein.

    Depositor

    Fred Gage

    Article

    Kaspar et al Proc Natl Acad Sci U S A. 2002 Feb 19;99

    Insert

    Cre
    

    Use

    AAV, Cre/Lox, and Mouse Targeting

    Tags

    EGFP, Myc, and NLS

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    Feb. 13, 2014

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. GFP-DroshaS300E/S302D

    Plasmid

    #62531

    Purpose

    Serine 300 of Drosha is mutated to glutamic acid and serine 302 is mutated to aspartic acid

    Depositor

    Bharat Ramratnam

    Article

    Tang et al Nucleic Acids Res. 2010 Oct;38(19):6610-

    Insert

    human Drosha with serine 300 changed to glutamic acid and serine 302 changed to aspartic acid (DROSHA Human)
    

    Use

    Tags

    GFP

    Expression

    Mammalian

    Mutation

    changed serine 300 to glutamic acid and serine 3…

    Promoter

    Available since

    March 20, 2015

    Availability

    Academic Institutions and Nonprofits only

19. pcDNA3.1-N-Myc_DW164AA + DED/AAA USP7

    Plasmid

    #131256

    Purpose

    Mammalian expression of N-terminally Myc-tagged USP7, with mutations in the TRAF-like domain (DW164AA) and UBL2 (DE758AA_D764A)

    Depositor

    Roger Woodgate

    Article

    Ashton et al J Mol Biol. 2021 Jan 22;433(2):166733. d

    Insert

    Ubiquitin carboxyl-terminal hydrolase 7 (USP7 Human)
    

    Use

    Tags

    Myc

    Expression

    Mammalian

    Mutation

    Contains point mutations that convert USP7 aspart…

    Promoter

    Available since

    Dec. 17, 2020

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. pcDNA3.1-GSDMD_1-275

    Plasmid

    #218230

    Purpose

    Gasdermin-D_1-275 is a pore-forming GSDMD formed by cleavage by host caspases. Transfection in HEK293 cells showed GSDMD 1-275 pores secrete 3CLpro, nucleocapsid; in excess, kills cells by pyroptosis

    Depositor

    Christopher Overall

    Article

    Grin et al Cell Rep. 2024 Dec 24;43(12):115080. doi

    Insert

    GSDMD (GSDMD Human)
    

    Use

    Tags

    flag

    Expression

    Mammalian

    Mutation

    construct only codes for amino acids 1-275

    Promoter

    Available since

    July 1, 2025

    Availability

    Industry, Academic Institutions, and Nonprofits

    

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