167,433 results

1. Cp PS Intein dCas9-VPR

   Plasmid

   #242031

   Purpose

   Blue-light-controlled release of dCas9-VPR from the cytoplasm to the nucleus.

   Depositor

   Vladislav Verkhusha

   Article

   Baloban et al Nat Commun. 2025 Sep 11;16(1):8263. doi:

   Insert

   Cp PS Intein dCas9-VPR
   

   Expression

   Mammalian

   Promoter

   CMV

   Available Since

   Sept. 16, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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2. pBAD42-BtuCEDFB

   Plasmid

   #237541

   Purpose

   plasmid encodes BtuC, BtuD, BtuE, BtuF, BtuB for enhanced solubilization of cobalamin proteins

   Depositor

   Squire Booker

   Article

   Lanz et al Biochemistry. 2018 Mar 6;57(9):1475-1490

   Inserts

   btuB
   btuF
   btuCED
   

   Expression

   Bacterial

   Promoter

   pBAD

   Available Since

   Sept. 15, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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3. AAV-hSyn-PiGM-Iq(mCherry)

   Plasmid

   #221604

   Purpose

   A recombinant AAV2 plasmid encoding the PiGM-Iq system with CRY2PHR, CIBN and mCherry as expression marker. hSynapsin promoter for panneuronal expression.

   Depositor

   John Lin

   Insert

   PiGM-Iq (mCherry)
   

   Use

   AAV

   Mutation

   RGS2 1-53 truncation

   Promoter

   Human Synapsin

   Available Since

   Sept. 8, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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4. pLV EF1alpha INTS4 K26/27A IRES Cherry

   Plasmid

   #228111

   Purpose

   Lentiviral expression of human INTS4 K26/27A

   Depositor

   Tom Misteli

   Article

   Sood et al Mol Cell. 2025 Mar 6;85(5):913-928.e8. d

   Insert

   INTS4 (INTS4 Human)
   

   Use

   Lentiviral

   Expression

   Mammalian

   Mutation

   Mutated Lysine 26 and 27 to Alanine

   Promoter

   EF 1alpha

   Available Since

   Aug. 19, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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5. pET30a-PmPPA-ET64

   Plasmid

   #234667

   Purpose

   Expression an ELP-tagged PmPPA enzyme

   Depositor

   Xianwei Liu

   Article

   Wu et al Chembiochem. 2025 Jan 13:e202401005. doi

   Insert

   pyrophosphatase
   

   Tags

   ELP

   Expression

   Bacterial

   Available Since

   July 24, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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6. NLRP3-NanoLuc Fusion Vector

   Plasmid

   #237189

   Purpose

   Express NLRP3-NanoLuc(R) Fusion Protein in Mammalian Cells under a CMV promoter

   Depositor

   Promega Corporation

   Has Service

   DNA

   Insert

   NLRP3 (NLRP3 Human)
   

   Tags

   NanoLuc (R)

   Expression

   Mammalian

   Promoter

   CMV

   Available Since

   July 14, 2025

   Availability

   Industry, Academic Institutions, and Nonprofits

   

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7. Tad-CBE2.4

   Plasmid

   #235055

   Purpose

   Expresses Tad-CBE2.4 in mammalian cells.

   Depositor

   Weixin Tang

   Article

   Wu et al Nat Biotechnol. 2025 Jul 7:10.1038/s4158

   Insert

   Tad-CBE2.4-SpCas9 D10A
   

   Use

   CRISPR

   Tags

   2xUGI, SV40NLS and bpNLS

   Expression

   Mammalian

   Available Since

   July 14, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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8. Tad-CBE(ACC3)

   Plasmid

   #235062

   Purpose

   Expresses Tad-CBE(ACC3) in mammalian cells.

   Depositor

   Weixin Tang

   Article

   Wu et al Nat Biotechnol. 2025 Jul 7:10.1038/s4158

   Insert

   Tad-CBE(ACC3)-SpCas9 D10A
   

   Use

   CRISPR

   Tags

   2xUGI, SV40NLS and bpNLS

   Expression

   Mammalian

   Available Since

   July 14, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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9. pA-CBh.TP-CNOT8-V5H6.MCh.Puro

   Plasmid

   #209947

   Purpose

   In mammalian cells expresses TP fused to a CNOT8 with a V5H6 tag. Also expresses an mCherry fluorescent protein and puromycin resistance marker.

   Depositor

   Kevin Weeks

   Article

   Hatfield et al Biochemistry. 2025 Sep 16;64(18):3854-38

   Inserts

   CCR4-NOT transcription complex subunit 8 (CNOT8 Human)
   mCherry fluorescent protein fused to puromycin resistance marker
   

   Tags

   TP (MS2 coat protein) and V5 epitope with H6 tag

   Expression

   Mammalian

   Promoter

   CBh and CMV

   Available Since

   July 2, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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10. Lenti-U6-sgRNA-BFP-Puro

    Plasmid

    #229014

    Purpose

    Perturb Seq lentiviral sgRNA vector

    Depositor

    Gary Hon

    Article

    Sivakumar et al bioRxiv [Preprint]. 2025 Jan 23:2025.01.

    Type

    Empty backbone

    Use

    Lentiviral

    Available Since

    May 20, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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11. AAV-hSyn-PiGM-Ii (173, 535/81, eGFP)

    Plasmid

    #221611

    Purpose

    AAV encoding the 173 amino acid version PiGM-Ii with minimal RGS10 domain, CRY2 (535 amino acid version), CIB1 (81 amino acid version).

    Depositor

    John Lin

    Insert

    PiGM-Ii (173, eGFP)
    

    Use

    AAV

    Mutation

    RGS10(truncation after amino acid 173)

    Promoter

    Human Synapsin

    Available Since

    May 20, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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12. IK331

    Plasmid

    #233653

    Purpose

    Dox-inducible blue light-inducible Cre-N; Cre-N229-pmag

    Depositor

    Wilson Wong

    Article

    Tous et al Sci Adv. 2025 May 9;11(19):eadt1971. doi

    Insert

    Cre-N229-pmag
    

    Expression

    Mammalian

    Mutation

    None

    Available Since

    May 12, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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13. IK332

    Plasmid

    #233654

    Purpose

    Dox-inducible blue light-inducible Cre-C; Cre-230C-nmag

    Depositor

    Wilson Wong

    Article

    Tous et al Sci Adv. 2025 May 9;11(19):eadt1971. doi

    Insert

    Cre-230C-nmag
    

    Expression

    Mammalian

    Mutation

    None

    Available Since

    May 12, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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14. 10xHis-3C-BRD4(42-459) BD1-BD2

    Plasmid

    #233886

    Purpose

    pRSF-DUET1 for protein overexpression of human BRD4

    Depositor

    Alessio Ciulli

    Article

    Hsia et al Nature. 2024 Mar;627(8002):204-211. doi:

    Insert

    BRD4 (BRD4 Human)
    

    Tags

    10x his 3C

    Expression

    Bacterial

    Promoter

    T7

    Available Since

    March 25, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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15. pCF.111

    Plasmid

    #227187

    Purpose

    pORTMAGE-Ec1 + supplement E. coli SSB

    Depositor

    Seth Shipman

    Article

    Fishman et al Nat Biotechnol. 2024 Sep 5. doi: 10.1038

    Insert

    CspRecT, mutL_E32K, E. coli SSB
    

    Expression

    Bacterial

    Mutation

    mutL E32K

    Available Since

    Dec. 4, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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16. pKDC.109

    Plasmid

    #227189

    Purpose

    T7 IPTG-driven Cas9

    Depositor

    Seth Shipman

    Article

    Fishman et al Nat Biotechnol. 2024 Sep 5. doi: 10.1038

    Insert

    SpyCas9
    

    Expression

    Bacterial

    Available Since

    Oct. 15, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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17. pRoRL

    Plasmid

    #213132

    Purpose

    Riboptoregulator circuit RoRL for blue-light-activated gene expression

    Depositor

    Andreas Moeglich

    Article

    Ranzani et al Nucleic Acids Res. 2024 Aug 10:gkae678.

    Type

    Empty backbone

    Use

    Synthetic Biology

    Expression

    Bacterial

    Available Since

    July 22, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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18. pcDNA3.1-H2-18 Heavy chain-SpyTag003

    Plasmid

    #216307

    Purpose

    Expresses anti-HER2 H2-18 Heavy chain-SpyTag003 in mammalian cells. To be paired with H2-18 light chain to form the anti-HER2 H2-18 Fab

    Depositor

    Mark Howarth

    Article

    Driscoll et al Nat Commun. 2024 Mar 16;15(1):2403. doi:

    Insert

    H2-18 Heavy chain-SpyTag003
    

    Use

    Affinity Reagent/ Antibody

    Tags

    His6 tag, Signal peptide, and SpyTag003

    Expression

    Mammalian

    Promoter

    T7 promoter

    Available Since

    June 26, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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19. AiP1862 - pAAV-AiE2566m-minBG-SYFP2-WPRE-BGHpA

    Plasmid

    #214561

    Purpose

    AiE2566m is an enhancer sequence, designed to drive AAV-mediated transgene expression in specific populations of brain cells

    Depositor

    Allen Institute for Brain Science, Bosiljka Tasic

    Article

    Ben-Simon et al Cell. 2025 May 16:S0092-8674(25)00513-6.

    Insert

    SYFP2
    

    Use

    AAV

    Promoter

    minBG

    Available Since

    June 24, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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20. AAVS1 EGFP-Sec61B

    Plasmid

    #207553

    Purpose

    Homologous recombination donor to integrate and expression cassette for EGFP-Sec61B in the AAVS1 locus of human cells

    Depositor

    Jens Schmidt

    Article

    Broadbent et al J Cell Biol. 2023 Jul 3;222(7):e20221007

    Insert

    TET inducible EGFP-Sec61B
    

    Tags

    EGFP

    Expression

    Mammalian

    Promoter

    Endogenous

    Available Since

    April 24, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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