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pHAGE-PIK3R1-R386*

Plasmid

#116604

Purpose

Lentiviral expression of PIK3R1 R386*

Depositor

Gordon Mills, Kenneth Scott

Article

Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

Insert

PIK3R1 (PIK3R1 Human)

Use

Lentiviral

Mutation

R386*

Available Since

March 14, 2019

Availability

Academic Institutions and Nonprofits only

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pHAGE-PIK3R1-D464N

Plasmid

#116584

Purpose

Lentiviral expression of PIK3R1 D464N

Depositor

Gordon Mills, Kenneth Scott

Article

Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

Insert

PIK3R1 (PIK3R1 Human)

Use

Lentiviral

Mutation

D464N

Available Since

March 14, 2019

Availability

Academic Institutions and Nonprofits only

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pHAGE-PIK3R1-G353R

Plasmid

#116591

Purpose

Lentiviral expression of PIK3R1 G353R

Depositor

Gordon Mills, Kenneth Scott

Article

Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

Insert

PIK3R1 (PIK3R1 Human)

Use

Lentiviral

Mutation

G353R

Available Since

March 14, 2019

Availability

Academic Institutions and Nonprofits only

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pHAGE-NOTCH2NL-G137L

Plasmid

#116439

Purpose

Lentiviral expression of NOTCH2NL G137L

Depositor

Gordon Mills, Kenneth Scott

Article

Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

Insert

NOTCH2NL (NOTCH2NLA Human)

Use

Lentiviral

Mutation

G137L

Available Since

March 14, 2019

Availability

Academic Institutions and Nonprofits only

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pHAGE-NOTCH2NL-Q172_G173delinsHC

Plasmid

#116440

Purpose

Lentiviral expression of NOTCH2NL Q172_G173delinsHC

Depositor

Gordon Mills, Kenneth Scott

Article

Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

Insert

NOTCH2NL (NOTCH2NLA Human)

Use

Lentiviral

Mutation

Q172_G173delinsHC

Available Since

March 14, 2019

Availability

Academic Institutions and Nonprofits only

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pHAGE-NOTCH2NL-R87M

Plasmid

#116441

Purpose

Lentiviral expression of NOTCH2NL R87M

Depositor

Gordon Mills, Kenneth Scott

Article

Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

Insert

NOTCH2NL (NOTCH2NLA Human)

Use

Lentiviral

Mutation

R87M

Available Since

March 14, 2019

Availability

Academic Institutions and Nonprofits only

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pHAGE-NOTCH2NL-S165F

Plasmid

#116442

Purpose

Lentiviral expression of NOTCH2NL S165F

Depositor

Gordon Mills, Kenneth Scott

Article

Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

Insert

NOTCH2NL (NOTCH2NLA Human)

Use

Lentiviral

Mutation

S165F

Available Since

March 14, 2019

Availability

Academic Institutions and Nonprofits only

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pHAGE-OXA1L-L57F

Plasmid

#116445

Purpose

Lentiviral expression of OXA1L L57F

Depositor

Gordon Mills, Kenneth Scott

Article

Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

Insert

OXA1L (OXA1L Human)

Use

Lentiviral

Mutation

L57F

Available Since

March 14, 2019

Availability

Academic Institutions and Nonprofits only

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pHAGE-OXA1L-P58S

Plasmid

#116446

Purpose

Lentiviral expression of OXA1L P58S

Depositor

Gordon Mills, Kenneth Scott

Article

Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

Insert

OXA1L (OXA1L Human)

Use

Lentiviral

Mutation

P58S

Available Since

March 14, 2019

Availability

Academic Institutions and Nonprofits only

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pHAGE-MRPS31-R219C

Plasmid

#116437

Purpose

Lentiviral expression of MRPS31 R219C

Depositor

Gordon Mills, Kenneth Scott

Article

Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

Insert

MRPS31 (MRPS31 Human)

Use

Lentiviral

Mutation

R219C

Available Since

March 14, 2019

Availability

Academic Institutions and Nonprofits only

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Toronto KnockOut version 3 library (TKOv3)

Pooled Library

#90294

Purpose

Optimized library offering improved accuracy, efficiency, and scalability for CRISPR screens compared to TKOv1

Depositor

Jason Moffat

Article

Hart et al G3 (Bethesda). 2017 Aug 7;7(8):2719-2727

Available Since

May 5, 2017

Availability

Academic Institutions and Nonprofits only
pNLF1-C_CBFA2T3:1-615

Plasmid

#211070

Purpose

Mammalian expression of full-length human CBFA2T3. C-terminal NanoLuc luciferase tag.

Depositor

Cheryl Arrowsmith

Article

Ackloo et al J Med Chem. 2025 Jan 23;68(2):1092-1112.

Insert

CBFA2T3:M1-R615 (CBFA2T3 Human)

Tags

NanoLuc luciferase

Expression

Mammalian

Mutation

not annotated isoform

Promoter

CMV

Available Since

March 19, 2024

Availability

Academic Institutions and Nonprofits only

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pNLF1-C_PRKCSH:1-527

Plasmid

#211091

Purpose

Mammalian expression of full-length human PRKCSH. C-terminal NanoLuc luciferase tag.

Depositor

Cheryl Arrowsmith

Article

Ackloo et al J Med Chem. 2025 Jan 23;68(2):1092-1112.

Insert

PRKCSH:M1-L527 (PRKCSH Human)

Tags

NanoLuc luciferase

Expression

Mammalian

Mutation

333-333: missing. A291T natural variant (VAR_028…

Promoter

CMV

Available Since

March 19, 2024

Availability

Academic Institutions and Nonprofits only

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pBiT3.1-C_RBBP4:1-425

Plasmid

#211153

Purpose

Mammalian expression of full-length human RBBP4. C-terminal HiBiT tag.

Depositor

Cheryl Arrowsmith

Article

Ackloo et al J Med Chem. 2025 Jan 23;68(2):1092-1112.

Insert

RBBP4:M1-S425 (RBBP4 Human)

Tags

GSSGGSSGVSGWRLFKKIS

Expression

Mammalian

Mutation

wild type

Promoter

CMV

Available Since

March 19, 2024

Availability

Academic Institutions and Nonprofits only

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pNLF1-C_PLCG1:1-1291

Plasmid

#211089

Purpose

Mammalian expression of full-length human PLCG1 isoform 2. C-terminal NanoLuc luciferase tag.

Depositor

Cheryl Arrowsmith

Article

Ackloo et al J Med Chem. 2025 Jan 23;68(2):1092-1112.

Insert

PLCG1:M1-L1291 (PLCG1 Human)

Tags

NanoLuc luciferase

Expression

Mammalian

Mutation

isoform 2. I813T natural variant (VAR_011908)

Promoter

CMV

Available Since

March 19, 2024

Availability

Academic Institutions and Nonprofits only

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pBiT3.1-N_ATG16L1:1-607

Plasmid

#211234

Purpose

Mammalian expression of full-length human ATG16L1. N-terminal HiBiT tag.

Depositor

Cheryl Arrowsmith

Article

Ackloo et al J Med Chem. 2025 Jan 23;68(2):1092-1112.

Insert

ATG16L1:M1-Y607 (ATG16L1 Human)

Tags

MVSGWRLFKKISGSSGGSSG

Expression

Mammalian

Mutation

T300A natural variant (VAR_021834)

Promoter

CMV

Available Since

March 19, 2024

Availability

Academic Institutions and Nonprofits only

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pBiT3.1-C_FBXW11:1-542

Plasmid

#211105

Purpose

Mammalian expression of full-length human FBXW11. C-terminal HiBiT tag.

Depositor

Cheryl Arrowsmith

Article

Ackloo et al J Med Chem. 2025 Jan 23;68(2):1092-1112.

Insert

FBXW11:M1-R542 (FBXW11 Human)

Tags

GSSGGSSGVSGWRLFKKIS

Expression

Mammalian

Mutation

wild type

Promoter

CMV

Available Since

March 19, 2024

Availability

Academic Institutions and Nonprofits only

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pNLF1-C_RAB7A:1-207

Plasmid

#211098

Purpose

Mammalian expression of full-length human RAB7A. C-terminal NanoLuc luciferase tag.

Depositor

Cheryl Arrowsmith

Article

Ackloo et al J Med Chem. 2025 Jan 23;68(2):1092-1112.

Insert

RAB7A:M1-C207 (RAB7A Human)

Tags

NanoLuc luciferase

Expression

Mammalian

Mutation

wild type

Promoter

CMV

Available Since

March 19, 2024

Availability

Academic Institutions and Nonprofits only

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pBiT3.1-N_DCAF11:1-546

Plasmid

#211197

Purpose

Mammalian expression of full-length human DCAF11. N-terminal HiBiT tag.

Depositor

Cheryl Arrowsmith

Article

Ackloo et al J Med Chem. 2025 Jan 23;68(2):1092-1112.

Insert

DCAF11:M1-Q546 (DCAF11 Human)

Tags

MVSGWRLFKKISGSSGGSSG

Expression

Mammalian

Mutation

R207H natural variant (VAR_020121)

Promoter

CMV

Available Since

March 19, 2024

Availability

Academic Institutions and Nonprofits only

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pBiT3.1-N_WDR62:1-1518

Plasmid

#211257

Purpose

Mammalian expression of full-length human WDR62 isoform 4. N-terminal HiBiT tag.

Depositor

Cheryl Arrowsmith

Article

Ackloo et al J Med Chem. 2025 Jan 23;68(2):1092-1112.

Insert

WDR62:M1-H1518 (WDR62 Human)

Tags

MVSGWRLFKKISGSSGGSSG

Expression

Mammalian

Mutation

isoform 4. L850S natural VAR_031299. Q1305L n…

Promoter

CMV

Available Since

July 2, 2024

Availability

Academic Institutions and Nonprofits only

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