We narrowed to 5,340 results for: 290

1. pHAGE-PIK3CA-E542K

   Plasmid

   #116479

   Purpose

   Lentiviral expression of PIK3CA E542K

   Depositor

   Gordon Mills, Kenneth Scott

   Article

   Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

   Insert

   PIK3CA (PIK3CA Human)
   

   Use

   Lentiviral

   Mutation

   E542K

   Available Since

   March 14, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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2. pC0048-CMV-dPspCas13b-longlinker-ADAR2DD(E488Q)

   Plasmid

   #103864

   Purpose

   dPspCas13b-ADAR2DD(E488Q) fusion that can be used to selectively edit adenosine to inosine in RNA molecules when used in conjuction with a guide RNA. Longer linker than pC0039.

   Depositor

   Feng Zhang

   Article

   Cox et al Science. 2017 Oct 25. pii: eaaq0180. doi

   Inserts

   PspCas13b
   huADAR2DD (ADARB1 Human)
   

   Use

   CRISPR

   Tags

   GSGGGGS and HIV NES

   Expression

   Mammalian

   Mutation

   Changed histidne 133 to alanine and histidine 105…

   Available Since

   Nov. 28, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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3. pDONR223_PIK3CA_p.E545K

   Plasmid

   #82881

   Purpose

   Gateway Donor vector containing PIK3CA, part of the Target Accelerator Plasmid Collection.

   Depositor

   Jesse Boehm, David Root, Matthew Meyerson

   Article

   Berger et al Cancer Cell. 2016 Aug 8;30(2):214-28. do

   Insert

   NM_006218 (PIK3CA Human)
   

   Use

   Gateway entry vector

   Mutation

   E545K

   Promoter

   None

   Available Since

   April 24, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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4. pmiR-report-MYB-WT

   Plasmid

   #141114

   Purpose

   Reporter plasmid of WT MYB in mammalian cells.

   Depositor

   Jianjun Chen

   Article

   Weng et al Cell Stem Cell. 2018 Feb 1;22(2):191-205

   Insert

   CMYB (MYB Human)
   

   Use

   Luciferase

   Expression

   Mammalian

   Available Since

   Oct. 13, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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5. pmiR-report-MYB-mut

   Plasmid

   #141115

   Purpose

   Reporter plasmid of mutant MYB in mammalian cells.

   Depositor

   Jianjun Chen

   Article

   Weng et al Cell Stem Cell. 2018 Feb 1;22(2):191-205

   Insert

   MYB (MYB Human)
   

   Use

   Luciferase

   Expression

   Mammalian

   Mutation

   A to T mutations at m6A sites

   Available Since

   Dec. 8, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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6. pLentiCMVblast_SLC38A2_wt

   Plasmid

   #156180

   Purpose

   CMV-driven expression of sgRNA-resistant SLC38A2 wild-type cDNA.

   Depositor

   Alec Kimmelman

   Article

   Parker et al Cancer Discov. 2020 Apr 27. pii: 2159-82

   Insert

   SLC38A2 (SLC38A2 Human)
   

   Expression

   Mammalian

   Mutation

   Silent mutations to prevent targeting by sgRNA se…

   Promoter

   CMV

   Available Since

   Sept. 22, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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7. pHAGE-PIK3CA-R88Q

   Plasmid

   #116538

   Purpose

   Lentiviral expression of PIK3CA R88Q

   Depositor

   Gordon Mills, Kenneth Scott

   Article

   Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

   Insert

   PIK3CA (PIK3CA Human)
   

   Use

   Lentiviral

   Mutation

   R88Q

   Available Since

   March 14, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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8. pHAGE-PIK3CA-C420R

   Plasmid

   #116457

   Purpose

   Lentiviral expression of PIK3CA C420R

   Depositor

   Gordon Mills, Kenneth Scott

   Article

   Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

   Insert

   PIK3CA (PIK3CA Human)
   

   Use

   Lentiviral

   Mutation

   C420R

   Available Since

   March 14, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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9. pCDF-MCM4/6

   Plasmid

   #116951

   Purpose

   Expresses human MCM4 and human MCM6

   Depositor

   James Chong

   Article

   Hesketh et al J Biol Chem. 2015 Mar 20;290(12):7973-9.

   Inserts

   Human MCM6 (MCM6 Human)
   Human MCM4 (MCM4 Human)
   

   Tags

   His6

   Expression

   Bacterial

   Available Since

   Nov. 12, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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10. pC0053-CMV-dPspCas13b-GS-ADAR2DD(E488Q)-delta-984-1090

    Plasmid

    #103869

    Purpose

    dPspCas13b-ADAR2DD(E488Q) fusion that can be used to selectively edit adenosine to inosine in RNA molecules when used in conjuction with a guide RNA. Cas13b is truncated to allow for expression by AAV

    Depositor

    Feng Zhang

    Article

    Cox et al Science. 2017 Oct 25. pii: eaaq0180. doi

    Inserts

    PspCas13b
    huADAR2DD (ADARB1 Human)
    

    Use

    CRISPR

    Tags

    GS and HIV NES

    Expression

    Mammalian

    Mutation

    Changed histidne 133 to alanine and histidine 105…

    Available Since

    Nov. 28, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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11. pC0039-CMV-dPspCas13b-GS-ADAR2DD(E488Q)

    Plasmid

    #103849

    Purpose

    dPspCas13b-ADAR2DD(E488Q) fusion that can be used to selectively edit adenosine to inosine in RNA molecules when used in conjuction with a guide RNA.

    Depositor

    Feng Zhang

    Article

    Cox et al Science. 2017 Oct 25. pii: eaaq0180. doi

    Inserts

    PspCas13b
    huADAR2DD (ADARB1 Human)
    

    Use

    CRISPR

    Tags

    GS and HIV NES

    Expression

    Mammalian

    Mutation

    Changed histidne 133 to alanine and histidine 105…

    Promoter

    CMV

    Available Since

    Nov. 28, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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12. pET32-MCM2/7

    Plasmid

    #116949

    Purpose

    Expresses human MCM2 and human MCM7

    Depositor

    James Chong

    Article

    Hesketh et al J Biol Chem. 2015 Mar 20;290(12):7973-9.

    Inserts

    Human MCM7 (MCM7 Human)
    Human MCM2 (MCM2 Human)
    

    Tags

    Thioredoxin, His6

    Expression

    Bacterial

    Available Since

    Oct. 24, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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13. PCDH-METTL14-R298P

    Plasmid

    #141113

    Purpose

    Overexpression of METTL14 mutant in mammalian cells.

    Depositor

    Jianjun Chen

    Article

    Weng et al Cell Stem Cell. 2018 Feb 1;22(2):191-205

    Insert

    HMETTL14 (METTL14 Human)
    

    Expression

    Mammalian

    Mutation

    Substitution - Missense, position 298, R➞P

    Available Since

    June 26, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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14. pLX304_zeo_mmFbxw7a

    Plasmid

    #160102

    Purpose

    Expresses murine Fbxw7 alpha in mammalian cells

    Depositor

    Rizwan Haq

    Article

    Gstalder et al Cancer Discov. 2020 May 5. pii: 2159-829

    Insert

    Fbxw7alpha (Fbxw7 Mouse)
    

    Use

    Lentiviral

    Expression

    Mammalian

    Available Since

    Oct. 13, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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15. pC0047-CMV-dPspCas13b-ADAR1DD(E1008Q)

    Plasmid

    #103863

    Purpose

    dPspCas13b-ADAR1DD(E1008Q) fusion that can be used to selectively edit adenosine to inosine in RNA molecules when used in conjuction with a guide RNA

    Depositor

    Feng Zhang

    Article

    Cox et al Science. 2017 Oct 25. pii: eaaq0180. doi

    Inserts

    PspCas13b
    huADAR1DD (ADAR Human)
    

    Use

    CRISPR

    Expression

    Mammalian

    Mutation

    Changed histidne 133 to alanine and histidine 105…

    Available Since

    Nov. 28, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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16. PLEX-PGK-ANXA11-mCerulean

    Plasmid

    #164214

    Purpose

    pLEX lentivirus backbone expresses mCerulean tagged ANXA11 under PGK promoter

    Depositor

    Jennifer Lippincott-Schwartz

    Article

    Liao et al Cell. 2019 Sep 19;179(1):147-164.e20. do

    Insert

    ANXA11 (ANXA11 Human)
    

    Use

    Lentiviral

    Tags

    mCerulean

    Promoter

    PGK

    Available Since

    Jan. 26, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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17. OCT4-GFP-2A-PURO transgenic reporter

    Plasmid

    #52379

    Purpose

    BAC recombineering generated construct, used as a reporter for OCT4 expression

    Depositor

    Jacob Hanna

    Article

    Gafni et al Nature. 2013 Dec 12;504(7479):282-6. doi

    Inserts

    GFP-2A-puro
    OCT4
    

    Expression

    Mammalian

    Promoter

    OCT4

    Available Since

    Oct. 10, 2014

    Availability

    Academic Institutions and Nonprofits only

    

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18. pmiRA1-MYC

    Plasmid

    #141121

    Purpose

    Lentiviral overexpression of MYC in mammalian cells.

    Depositor

    Jianjun Chen

    Article

    Weng et al Cell Stem Cell. 2018 Feb 1;22(2):191-205

    Insert

    MYC (MYC Human)
    

    Use

    Lentiviral

    Tags

    HA

    Expression

    Mammalian

    Available Since

    June 26, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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19. pQCXIP-mCherry-Halo-YAP1

    Plasmid

    #128336

    Purpose

    Retrovirus construct to express mCherry-Halo-YAP1

    Depositor

    Yutaka Hata

    Article

    Maruyama et al Mol Cancer Res. 2018 Feb;16(2):197-211.

    Insert

    YAP1 (YAP1 Human)
    

    Use

    Retroviral

    Tags

    mCherry and Halo-tag

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    Feb. 26, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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20. pKLV2-U6gRNA5(LIN28A_5-4)-PGKpuroBFP-W

    Plasmid

    #211969

    Purpose

    Express gRNA against LIN28A with puro and BFP

    Depositor

    Kosuke Yusa

    Article

    Ishikawa et al Commun Biol. 2023 Dec 28;6(1):1290. doi:

    Insert

    sgRNA targeting LIN28A (LIN28A Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    Human U6 promoter

    Available Since

    Jan. 24, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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