We narrowed to 13,644 results for: crispr cas9

1. AAV-hSyn-mCherry-P2A-Cre-WPRE (AAV1)

   Viral Prep

   #107312-AAV1

   Purpose

   Ready-to-use AAV1 particles produced from AAV-hSyn-mCherry-P2A-Cre-WPRE (#107312). In addition to the viral particles, you will also receive purified AAV-hSyn-mCherry-P2A-Cre-WPRE plasmid DNA. hSyn-driven expression of mCherry and Cre (physically separate). These AAV preparations are suitable purity for injection into animals.

   Depositor

   Hui Yang

   Article

   Zhou et al Nat Neurosci. 2018 Jan 15. pii: 10.1038/

   Tags

   mCherry (physically separate, not a fusion protein)

   Available Since

   Oct. 28, 2021

   Availability

   Academic Institutions and Nonprofits only

2. Plas-CRISPR_reporter

   Plasmid

   #157658

   Purpose

   CRISPR reporter for mRNA quantification, integrative plasmid into NPR2 gene

   Depositor

   Frank Albert

   Article

   Brion et al Elife. 2020 Nov 16;9. pii: 60645. doi: 1

   Insert

   dCAS9-VP64, mCherry, KanMX
   

   Use

   Insert storage (replicative in e. coli)

   Mutation

   N28D in mCherry- please see depositor comments be…

   Available Since

   Sept. 15, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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3. pCRISPRa_all-in-one

   Plasmid

   #183695

   Purpose

   Expresses CRISPRa components including dCas9-VP64, Synergistic Activation Mediators (SAM), mCherry, and gRNA expression cassette, blasticidin selective

   Depositor

   Edward Avezov

   Article

   Melo et al Nat Commun. 2022 May 6;13(1):2501. doi:

   Type

   Empty backbone

   Use

   CRISPR

   Available Since

   April 14, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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4. pCRISPR-cBEST

   Plasmid

   #125689

   Purpose

   C to T base editor for actinomycetes

   Depositor

   Tilmann Weber

   Article

   Tong et al Proc Natl Acad Sci U S A. 2019 Oct 8;116

   Insert

   streptomyces codon optimized spCas9n (D10A), modified sgRNA casette, streptomyces codon optimized rAPOBEC1
   

   Use

   CRISPR and Synthetic Biology

   Promoter

   ermE*/tipA

   Available Since

   Feb. 7, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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5. pCRISPR-mcBEST

   Plasmid

   #209416

   Purpose

   Plasmid for multiplexed cytosine base editing in streptomycetes

   Depositor

   Tilmann Weber

   Article

   Whitford et al ACS Synth Biol. 2023 Aug 18;12(8):2353-2

   Inserts

   Codon optimized APOBEC1-nCas9-UGI fusion protein
   csy4 from Pseudomonas aeruginosa PAO1
   

   Use

   CRISPR and Synthetic Biology

   Promoter

   base editing cassette: PtipA ; sgRNAs: PkasO* an…

   Available Since

   Dec. 20, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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6. PL-CRISPR.EFS.tRFP-gIfngr1-1

   Plasmid

   #166479

   Purpose

   Expresses spCas9, tRFP and a gRNA targeting mouse Ifngr1

   Depositor

   Shuguo Sun

   Article

   Yu et al Mol Cell. 2021 Feb 13. pii: S1097-2765(2

   Insert

   gRNA for mouse Ifngr1 (Ifngr1 Mouse)
   

   Use

   Lentiviral

   Available Since

   April 9, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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7. PL-CRISPR.EFS.tRFP-gIfngr1-2

   Plasmid

   #166480

   Purpose

   Expresses spCas9, tRFP and a gRNA targeting mouse Ifngr1

   Depositor

   Shuguo Sun

   Article

   Yu et al Mol Cell. 2021 Feb 13. pii: S1097-2765(2

   Insert

   gRNA for mouse Ifngr1 (Ifngr1 Mouse)
   

   Use

   Lentiviral

   Available Since

   April 7, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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8. pCRISPR-cBEST-v2-PermE

   Plasmid

   #209446

   Purpose

   improved pCRISPR-cBEST plasmid with optimized sgRNA cloning site

   Depositor

   Tilmann Weber

   Article

   Maleckis et al ACS Chem Biol. 2024 Feb 10. doi: 10.1021

   Insert

   Codon optimized APOBEC1-nCas9-UGI fusion protein
   

   Use

   CRISPR and Synthetic Biology

   Promoter

   PtipA; sgRNA expression from ermE* promoter

   Available Since

   March 13, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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9. pCRISPR-cBEST-v2-SF14P

   Plasmid

   #209448

   Purpose

   improved pCRISPR-cBEST plasmid with optimized sgRNA cloning site and expression of the sgRNA from the SF14P promoter

   Depositor

   Tilmann Weber

   Article

   Maleckis et al ACS Chem Biol. 2024 Feb 10. doi: 10.1021

   Insert

   Codon optimized APOBEC1-nCas9-UGI fusion protein
   

   Use

   CRISPR and Synthetic Biology

   Promoter

   PtipA; sgRNA expression from SF14P promoter

   Available Since

   March 13, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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10. pCRISPR-cBEST-v2-kasOP*

    Plasmid

    #209447

    Purpose

    improved pCRISPR-cBEST plasmid with optimized sgRNA cloning site and expression of the sgRNA from the kasOP* promoter

    Depositor

    Tilmann Weber

    Article

    Maleckis et al ACS Chem Biol. 2024 Feb 10. doi: 10.1021

    Insert

    Codon optimized APOBEC1-nCas9-UGI fusion protein
    

    Use

    CRISPR and Synthetic Biology

    Promoter

    PtipA; sgRNA expression from kasOP* promoter

    Available Since

    March 13, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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11. Lenti-CRISPR-v2-gYap-1

    Plasmid

    #166481

    Purpose

    Expresses spCas9 and a gRNA targeting mouse Yap

    Depositor

    Shuguo Sun

    Article

    Yu et al Mol Cell. 2021 Feb 13. pii: S1097-2765(2

    Insert

    gRNA for mouse Yap (Yap1 Mouse)
    

    Use

    Lentiviral

    Available Since

    May 13, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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12. Lenti-CRISPR-V2-gYap-2

    Plasmid

    #166482

    Purpose

    Expresses spCas9 and a gRNA targeting mouse Yap

    Depositor

    Shuguo Sun

    Article

    Yu et al Mol Cell. 2021 Feb 13. pii: S1097-2765(2

    Insert

    gRNA for mouse Yap (Yap1 Mouse)
    

    Use

    Lentiviral

    Available Since

    May 13, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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13. pYJ06-CRISPR-SOX17-E2-gRNA1

    Plasmid

    #131051

    Purpose

    SOX17 Knock out

    Depositor

    Xiaojun Lian

    Insert

    SOX17 Exon2 gRNA1 (SOX17 Human)
    

    Use

    CRISPR

    Expression

    Mammalian

    Available Since

    Oct. 3, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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14. pYJ07-CRISPR-SOX17-E2-gRNA2

    Plasmid

    #131052

    Purpose

    SOX17 Knock out

    Depositor

    Xiaojun Lian

    Insert

    SOX17 Exon2 gRNA2 (SOX17 Human)
    

    Use

    CRISPR

    Expression

    Mammalian

    Available Since

    Oct. 3, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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15. pYJ08-CRISPR-SOX17-E1-gRNA1

    Plasmid

    #131053

    Purpose

    SOX17 Knock out

    Depositor

    Xiaojun Lian

    Insert

    SOX17 Exon1 gRNA1 (SOX17 Human)
    

    Use

    CRISPR

    Expression

    Mammalian

    Available Since

    Oct. 3, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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16. lentiGuide-Puro PRMT5-CRISPRi

    Plasmid

    #164637

    Purpose

    lentiGuide-Puro backbone with cloned target sequence for human PRMT5. The insert is: 5´- CACCGAGCCGCGTGTCCAGCGGGA-3. sgRNA achieves a downregulation of PRMT5 in combination with dCAS9-KRAB-MCP2

    Depositor

    Günter Schneider

    Insert

    target guide sequence PRMT5 inhibition (PRMT5 Human)
    

    Use

    CRISPR and Lentiviral; Interference

    Expression

    Mammalian

    Promoter

    U6 and EF1A

    Available Since

    May 9, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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17. pLKO5-SgHottip-GFP-CRISPRa

    Plasmid

    #134990

    Purpose

    dCas9-mediated activation of HOTTIP in mammalian cells

    Depositor

    Suming Huang

    Article

    Luo et al Cancer Cell. 2019 Dec 9;36(6):645-659.e8

    Insert

    HOTTIP (HOTTIP Human)
    

    Use

    Lentiviral

    Tags

    GFP

    Expression

    Bacterial and Mammalian

    Promoter

    U6

    Available Since

    May 31, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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18. pLKO5-SgHottip-GFP-CRISPRi

    Plasmid

    #134989

    Purpose

    dCas9-mediated inactivation of HOTTIP in mammalian cells

    Depositor

    Suming Huang

    Article

    Luo et al Cancer Cell. 2019 Dec 9;36(6):645-659.e8

    Insert

    HOTTIP (HOTTIP Human)
    

    Use

    Lentiviral

    Tags

    GFP

    Expression

    Bacterial and Mammalian

    Promoter

    U6

    Available Since

    May 31, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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19. pSB-TRE-CRISPRoff-EF1A-TetOn

    Plasmid

    #203355

    Purpose

    Drug-inducible expression of CRISPRoff components needed for DNA methylation and gene repression with Sleeping Beauty backbone

    Depositor

    Jonathan Brunger

    Article

    Gil et al Bio Protoc. 2024 Jan 5;14(1):e4913. doi:

    Insert

    CRISPRoff-TetOn
    

    Available Since

    Jan. 17, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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20. Multiplex-CRISPR-miR-200FAM-T2A-GFP

    Plasmid

    #179856

    Purpose

    to delete miR200 family genes including miR-141, miR-200c, miR-429 and miR-200b

    Depositor

    Brendan Jenkins

    Article

    Yu et al Oncogene. 2021 Oct 19. pii: 10.1038/s413

    Insert

    hsa-miR-200 family (miR-200b, miR-200a, miR-429, miR-141 and miR-200c ) (MIR141, MIR200B, MIR429, MIR200C, MIR200A Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Available Since

    March 22, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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