We narrowed to 9,474 results for: CAG

1. ERBB4 gRNA (BRDN0001149467)

   Plasmid

   #76196

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human ERBB4

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   ERBB4 (ERBB4 Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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2. CDK11A gRNA (BRDN0001147530)

   Plasmid

   #75892

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human CDK11A

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   CDK11A (CDK11A Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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3. pAAVS1-NDi-CRISPRi (Gen1)

   Plasmid

   #73497

   Purpose

   Dox-inducible CRISPR interference (CRISPRi) knock in construct into the AAVS1 locus with mCherry marker

   Depositor

   Bruce Conklin

   Article

   Mandegar et al Cell Stem Cell. 2016 Apr 7;18(4):541-53.

   Inserts

   dCas9-KRAB-P2A-mCherry
   rtTA
   

   Use

   CRISPR

   Tags

   HA, KRAB, and NLS

   Expression

   Mammalian

   Mutation

   D10A, H840A (catalytically deactivated Cas9)

   Promoter

   CAG and TRE3G

   Available Since

   Dec. 7, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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4. LSL-Cas9-Rosa26TV

   Plasmid

   #61408

   Purpose

   Cre-dependent Cas9 expression plasmid and targeting vector for the mouse Rosa26 locus. Cas9 expression is Cre-dependent and the targeting vector has positive (Neo) and negative (DTA) selection.

   Depositor

   Feng Zhang

   Article

   Platt et al Cell. 2014 Sep 24. pii: S0092-8674(14)01

   Inserts

   Cas9
   EGFP
   

   Use

   CRISPR, Cre/Lox, and Mouse Targeting

   Tags

   3xFLAG and P2A

   Expression

   Mammalian

   Mutation

   human codon optimized

   Promoter

   CAG

   Available Since

   Jan. 15, 2015

   Availability

   Academic Institutions and Nonprofits only

   

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5. pAAVS1-NDi-CRISPRi (Gen2)

   Plasmid

   #73498

   Purpose

   Dox-inducible CRISPR interference (CRISPRi) knock in construct into the AAVS1 locus

   Depositor

   Bruce Conklin

   Article

   Mandegar et al Cell Stem Cell. 2016 Apr 7;18(4):541-53.

   Inserts

   dCas9-KRAB
   rtTA
   

   Use

   CRISPR

   Tags

   HA, KRAB, and NLS

   Expression

   Mammalian

   Mutation

   D10A, H840A (catalytically deactivated Cas9)

   Promoter

   CAG and TRE3G

   Available Since

   Dec. 7, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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6. scAAV-Cre

   Plasmid

   #177933

   Purpose

   Expresses Cre-recombinase and can be packaged into AAV particles.

   Depositor

   Roland Rad

   Article

   Kaltenbacher et al Nat Protoc. 2022 Apr;17(4):1142-1188. do

   Insert

   CAG-Cre
   

   Use

   AAV

   Expression

   Mammalian

   Promoter

   U6

   Available Since

   Nov. 8, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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7. pAAV uN2C GFP (Ctl)

   Plasmid

   #224355

   Purpose

   Express GFP tagged upsteram ORF of NOTCH2NLC with a control size (12x) of GGC repeats

   Depositor

   Nicolas Charlet-Berguerand

   Article

   Boivin et al Neuron. 2021 Jun 2;109(11):1825-1835.e5.

   Insert

   uN2C
   

   Use

   AAV

   Tags

   eGFP

   Expression

   Mammalian

   Mutation

   Codon-optimized for expression in human, so no pu…

   Promoter

   CMV + chimeric intyron (CAG)

   Available Since

   Oct. 7, 2024

   Availability

   Industry, Academic Institutions, and Nonprofits

   

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8. pCXLE-SOX2-p2a-KLF4

   Plasmid

   #193292

   Purpose

   episomal hSK (expressing human SOX2 + KLF4)

   Depositor

   Hans Schöler

   Article

   MacCarthy et al Cell Stem Cell. 2024 Jan 4;31(1):127-147

   Insert

   SOX2-p2a-KLF4 (SOX2, KLF4 Human)
   

   Expression

   Mammalian

   Mutation

   F2A of original pCXLE-SK vector was replaced with…

   Promoter

   CAG

   Available Since

   Dec. 14, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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9. ISDra2-TnpB-mCherry-U6-ωRNA*

   Plasmid

   #212967

   Purpose

   Expression vector for expression of ISDra2-TnpB driven by chicken β-actin promoter and mCherry driven by CMV promoter

   Depositor

   Chunlong Xu

   Article

   Li et al Nat Commun. 2024 Jan 27;15(1):831. doi:

   Inserts

   ISDra2-TnpB-T2A-mCherry
   ωRNA*
   

   Use

   CRISPR

   Tags

   NLS and NLS-FLAG

   Expression

   Mammalian

   Promoter

   CAG, T7 and U6

   Available Since

   Feb. 20, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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10. pACEMam2-TRPML1

    Plasmid

    #238303

    Purpose

    Expression of human TRPML1 in mammalian cells

    Depositor

    Pravin Mahajan

    Article

    Judith et al Structure, 2025

    Insert

    TRPML1 (MCOLN1 Human)
    

    Tags

    8xHis-3xFLAG-TEV

    Expression

    Mammalian

    Promoter

    hybrid CAG promoter

    Available Since

    June 17, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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11. pAAV-CaMKII-ChrimsonR-tdTomato

    Plasmid

    #99231

    Purpose

    AAV-mediated expression of ChrimsonR-tdTomato under the CaMKII promoter. tdTomato has codons varied between the first and second tandem repeats to reduce recombination. Using SV40 signal.

    Depositor

    Edward Boyden

    Article

    Klapoetke et al Nat Methods. 2014 Mar;11(3):338-46. doi:

    Insert

    ChrimsonR-tdTomato
    

    Use

    AAV

    Tags

    tdTomato

    Expression

    Mammalian

    Mutation

    Chrimson K176R mutant

    Promoter

    CaMKII

    Available Since

    Aug. 22, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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12. pOTTC1080 - prRosa26v2 LSL FLAG-SpCas9

    Plasmid

    #113163

    Purpose

    A donor plasmid with homologous arms matching rat Rosa26 and expressing a Cre-dependent FLAG-tagged SpCas9

    Depositor

    Brandon Harvey

    Article

    Back et al Neuron. 2019 Feb 8. pii: S0896-6273(19)3

    Insert

    SpCas9
    

    Use

    CRISPR

    Tags

    FLAG

    Expression

    Mammalian

    Promoter

    CAG

    Available Since

    March 28, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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13. pCXLE-Sox2-T2A-Klf4-E2A-Myc

    Plasmid

    #210018

    Purpose

    episomal SKM (expressing mouse Sox2 + Klf4 + Myc) for integration-free naïve reset

    Depositor

    Hans Schöler

    Article

    MacCarthy et al Cell Stem Cell. 2024 Jan 4;31(1):127-147

    Insert

    Sox2-t2a-Klf4-e2a-cMyc (Klf4, Sox2 Mouse)
    

    Expression

    Mammalian

    Promoter

    CAG

    Available Since

    Dec. 14, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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14. pNJP

    Plasmid

    #115494

    Purpose

    Expression vector for NLS-iRFP-NLS, JNK KTR-mCherry, and mKO-MK2 in mammalian cells

    Depositor

    Kazuhiro Aoki

    Article

    Miura et al Cell Rep. 2018 Sep 4;24(10):2658-2668. d

    Insert

    NLS-iRFP-NLS-P2A-JNK KTR-mCherry-P2A-mKO-MK2 (MAPK14, MAPK8 Synthetic, Human, Mouse)
    

    Tags

    iRFP, mCherry, and mKO

    Expression

    Mammalian

    Mutation

    mCherry S227F, mCherry G229R, mKO V211G

    Promoter

    CAG

    Available Since

    Dec. 17, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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15. pB-3xFlag-dCas13-mTET2CD

    Plasmid

    #228234

    Purpose

    For targeted tethering of the catalytic domain of mouse TET2 using dCas13

    Depositor

    Chuan He

    Article

    Zou et al Nature. 2024 Oct 2. doi: 10.1038/s41586-

    Inserts

    dCas13
    TET2 (Tet2 Mouse)
    

    Use

    CRISPR

    Expression

    Mammalian

    Mutation

    CD (cysteine-rich, dioxygenase domain) truncation…

    Promoter

    CAG

    Available Since

    Nov. 5, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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16. pCXLE-SOX2AV-p2a-KLF4

    Plasmid

    #193291

    Purpose

    episomal expressing human SOX2A61V + KLF4

    Depositor

    Hans Schöler

    Article

    MacCarthy et al Cell Stem Cell. 2024 Jan 4;31(1):127-147

    Insert

    SOX2AV-p2a-KLF4 (SOX2, KLF4 Human)
    

    Expression

    Mammalian

    Mutation

    SOX2A61V is a highly cooperative point mutant of …

    Promoter

    CAG

    Available Since

    Dec. 14, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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17. pCXLE-mCherry-t2a-SOX2-p2a-KLF4

    Plasmid

    #193296

    Purpose

    episomal mCherry-hSK (expressing mCherry + human SOX2 + KLF4)

    Depositor

    Hans Schöler

    Article

    MacCarthy et al Cell Stem Cell. 2024 Jan 4;31(1):127-147

    Insert

    mCherry-t2a-SOX2-p2a-KLF4 (SOX2, KLF4 Human, Discosoma)
    

    Expression

    Mammalian

    Promoter

    CAG

    Available Since

    Dec. 13, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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18. pB-3xFlag-dCas13-mTET2HxDCD

    Plasmid

    #228235

    Purpose

    For targeted tethering of an inactive mutant (HxD) of the catalytic domain of mouse TET2 using dCas13

    Depositor

    Chuan He

    Article

    Zou et al Nature. 2024 Oct 2. doi: 10.1038/s41586-

    Inserts

    dCas13
    TET2 (Tet2 Mouse)
    

    Use

    CRISPR

    Expression

    Mammalian

    Mutation

    CD (cysteine-rich, dioxygenase domain) truncation…

    Promoter

    CAG

    Available Since

    Jan. 6, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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19. AAV-Syn-FLPX-rc [ChrimsonR-tdTomato]

    Plasmid

    #128589

    Purpose

    AAV-mediated expression of ChrimsonR-tdTomato under the Syn promoter in frt/reversed (Flp-dependent) manner. tdTomato has codons varied to reduce recombination.

    Depositor

    Edward Boyden

    Article

    Klapoetke et al Nat Methods. 2014 Mar;11(3):338-46. doi:

    Has Service

    AAV8

    Insert

    ChrimsonR-tdTomato
    

    Use

    AAV

    Tags

    tdTomato (codon diversified version)

    Expression

    Mammalian

    Mutation

    Chrimson K176R mutant

    Promoter

    Syn

    Available Since

    Sept. 25, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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20. pDONOR-MARINA

    Plasmid

    #223328

    Purpose

    DONOR vector for genomic integration of MARINA voltage sensitive indicator gene from Platisa et al., 2017 (10.1021/acschemneuro.6b00234).

    Depositor

    Jonathan Arias

    Article

    Petruskeviciute et al Stem Cell Res. 2024 Dec 12;82:103628. do

    Inserts

    MARINA
    KIR2.1 channel Golgi-to-plasma membrane trafficking signal
    

    Use

    CRISPR and Synthetic Biology

    Tags

    mCherry and super-ecliptic pHluorin

    Expression

    Mammalian

    Promoter

    CAG

    Available Since

    Dec. 13, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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