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TRCN0000297275

Plasmid

#78152

Purpose

shCDK4 targeting 3UTR

Depositor

William Hahn

Article

Hong et al Nat Commun. 2016 Jun 22;7:11987. doi: 10

Insert

CDK4 (CDK4 Human)

Use

RNAi

Promoter

hU6

Available Since

June 22, 2016

Availability

Academic Institutions and Nonprofits only
RCAS-Neu HA SIINFEKL

Plasmid

#125832

Purpose

Retroviral expression of rat Neu cDNA

Depositor

Yi Li

Article

Du et al Proc Natl Acad Sci U S A. 2006 Nov 14;10

Insert

Neu (Erbb2 Rat)

Use

Retroviral

Tags

2x HA and SIINFEKL

Expression

Mammalian

Mutation

Val to Glu point mutation of codon 664 and trunca…

Available Since

July 23, 2019

Availability

Academic Institutions and Nonprofits only

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DYRK1A gRNA (BRDN0001149496)

Plasmid

#76753

Purpose

3rd generation lentiviral gRNA plasmid targeting human DYRK1A

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

DYRK1A (DYRK1A Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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DYRK1A gRNA (BRDN0001148321)

Plasmid

#76754

Purpose

3rd generation lentiviral gRNA plasmid targeting human DYRK1A

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

DYRK1A (DYRK1A Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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MARK2 gRNA (BRDN0001146902)

Plasmid

#77592

Purpose

3rd generation lentiviral gRNA plasmid targeting human MARK2

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

MARK2 (MARK2 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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KDR gRNA (BRDN0001146819)

Plasmid

#77755

Purpose

3rd generation lentiviral gRNA plasmid targeting human KDR

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

KDR (KDR Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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KDR gRNA (BRDN0001146648)

Plasmid

#77756

Purpose

3rd generation lentiviral gRNA plasmid targeting human KDR

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

KDR (KDR Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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KDR gRNA (BRDN0001144938)

Plasmid

#77757

Purpose

3rd generation lentiviral gRNA plasmid targeting human KDR

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

KDR (KDR Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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hu-TLR4 299 snp-flag pDEST40

Plasmid

#42647

Purpose

destination vector for expression of human TLR4 299 SNP in mammalian cells

Depositor

Scott Friedman

Article

Guo et al Hepatology. 2009 Mar;49(3):960-8. doi: 1

Insert

TLR4 299 SNP (TLR4 Human)

Tags

Flag

Expression

Mammalian

Mutation

D299G

Promoter

CMV

Available Since

March 3, 2014

Availability

Academic Institutions and Nonprofits only
MAST2 gRNA (BRDN0001146731)

Plasmid

#76937

Purpose

3rd generation lentiviral gRNA plasmid targeting human MAST2

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

MAST2 (MAST2 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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TRCN0000279887

Plasmid

#78153

Purpose

shCDK4 targeting CDS

Depositor

William Hahn

Article

Hong et al Nat Commun. 2016 Jun 22;7:11987. doi: 10

Insert

CDK4 (CDK4 Human)

Use

Lentiviral and RNAi

Promoter

hU6 and hU6

Available Since

June 22, 2016

Availability

Academic Institutions and Nonprofits only
TRCN0000279952

Plasmid

#78155

Purpose

shCDK4 targeting 3UTR

Depositor

William Hahn

Article

Hong et al Nat Commun. 2016 Jun 22;7:11987. doi: 10

Insert

CDK4 (CDK4 Human)

Use

Lentiviral and RNAi

Promoter

hU6 and hU6

Available Since

June 22, 2016

Availability

Academic Institutions and Nonprofits only
pRRLNeo-pEF1a-p53ashL344P-mKate2-splitmVenusN

Plasmid

#69586

Purpose

Expresses mutated p53-L344P tagged with mKate2 and split N-term mVenus

Depositor

Galit Lahav

Article

Gaglia et al Mol Syst Biol. 2014 Oct 24;10:753. doi:

Insert

p53-L344P (TP53 Human)

Use

Lentiviral

Tags

mKate2 and split mVenus - N term

Expression

Mammalian

Mutation

p53 L344P mutation that prevents dimerization and…

Promoter

EF1alpha

Available Since

April 14, 2020

Availability

Academic Institutions and Nonprofits only

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TRCN0000279953

Plasmid

#78154

Purpose

shCDK4 targeting CDS

Depositor

William Hahn

Article

Hong et al Nat Commun. 2016 Jun 22;7:11987. doi: 10

Insert

CDK4 (CDK4 Human)

Use

Lentiviral and RNAi

Promoter

hU6 and hU6

Available Since

June 22, 2016

Availability

Academic Institutions and Nonprofits only
DYRK1A gRNA (BRDN0001149042)

Plasmid

#76756

Purpose

3rd generation lentiviral gRNA plasmid targeting human DYRK1A

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

DYRK1A (DYRK1A Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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MAP2K1 gRNA (BRDN0001146127)

Plasmid

#76213

Purpose

3rd generation lentiviral gRNA plasmid targeting human MAP2K1

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

MAP2K1 (MAP2K1 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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MAP4K3 gRNA (BRDN0001145375)

Plasmid

#76404

Purpose

3rd generation lentiviral gRNA plasmid targeting human MAP4K3

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

MAP4K3 (MAP4K3 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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MAP4K3 gRNA (BRDN0001145020)

Plasmid

#76405

Purpose

3rd generation lentiviral gRNA plasmid targeting human MAP4K3

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

MAP4K3 (MAP4K3 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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MAP4K3 gRNA (BRDN0001147653)

Plasmid

#76406

Purpose

3rd generation lentiviral gRNA plasmid targeting human MAP4K3

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

MAP4K3 (MAP4K3 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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pEMS1162

Plasmid

#29077

Purpose

Expression of the eGFP reporter gene was not detected in the brain and eye.

Depositor

Elizabeth Simpson

Article

Simpson et al Hum Gene Ther. 2018 Jul 31. doi: 10.1089

Insert

Ple94 (GPR88 Human)

Use

Pleiades promoter project [sic, pleaides plieades]

Tags

EGFP-NLS

Available Since

Aug. 3, 2011

Availability

Academic Institutions and Nonprofits only

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