We narrowed to 6,021 results for: RIK

1. pcDHa_mDDX5_FL_wt

   Plasmid

   #88869

   Purpose

   constitutive expression of Ha-DDX5 in mammalian cells

   Depositor

   Dan Littman

   Article

   Huang et al Nature. 2015 Dec 24;528(7583):517-22. do

   Insert

   DDX5 (Ddx5 Mouse)
   

   Tags

   HA

   Expression

   Mammalian

   Promoter

   CMV

   Available Since

   June 19, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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2. pcDNA3-sACE2-WT(732)-8h

   Plasmid

   #154101

   Purpose

   Mammalian expression plasmid for dimeric soluble ACE2 (8his tag)

   Depositor

   Erik Procko

   Article

   Chan et al Science. 2020 Sep 4;369(6508):1261-1265.

   Insert

   Angiotensin-converting enzyme 2 (ACE2 Human)
   

   Tags

   Short GSG linker and 8his tag

   Expression

   Mammalian

   Mutation

   Extracellular, soluble protease and neck domains …

   Promoter

   CMV

   Available Since

   June 24, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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3. pB-3xFlag-dCas13-mTET2HxDCD

   Plasmid

   #228235

   Purpose

   For targeted tethering of an inactive mutant (HxD) of the catalytic domain of mouse TET2 using dCas13

   Depositor

   Chuan He

   Article

   Zou et al Nature. 2024 Oct 2. doi: 10.1038/s41586-

   Inserts

   dCas13
   TET2 (Tet2 Mouse)
   

   Use

   CRISPR

   Expression

   Mammalian

   Mutation

   CD (cysteine-rich, dioxygenase domain) truncation…

   Promoter

   CAG

   Available Since

   Jan. 6, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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4. pEJS-HZ79 All-in-one AAV-U1a-NmeABE8e-2xBPSV40-U6-Rosa26_V2

   Plasmid

   #199261

   Purpose

   Optimized single AAV vector for expressing N-terminal fusion Nme2Cas9-ABE8e and one U6 driven sgRNA targeting mouse Rosa26 gene. This optimized construct showed improved in vivo editing efficiency.

   Depositor

   Erik Sontheimer

   Article

   Zhang et al GEN Biotechnol. 2022 Jun 1;1(3):285-299.

   Insert

   NmeABE8e
   

   Use

   AAV and CRISPR

   Tags

   NLS

   Expression

   Mammalian

   Promoter

   U1a promoter

   Available Since

   April 10, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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5. pEF5-FRT-V5-DEST-GFP-Kif26b

   Plasmid

   #102862

   Purpose

   Expresses GFP-Kif26b in mammalian cells

   Depositor

   Henry Ho

   Article

   Susman et al Elife. 2017 Sep 8;6. pii: e26509. doi: 1

   Insert

   Mouse Kif26b (Kif26b Mouse)
   

   Tags

   GFP

   Expression

   Mammalian

   Promoter

   EF1A

   Available Since

   Dec. 8, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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6. pcDNA3-N-HA-NEK7 K64M

   Plasmid

   #75143

   Purpose

   Expresses N-terminal HA-tagged NEK7 (with a K64M substitution; kinase dead) in mammalian cells

   Depositor

   Bruce Beutler

   Article

   Shi et al Nat Immunol. 2016 Mar;17(3):250-8. doi:

   Insert

   NIMA (never in mitosis gene a)-related expressed kinase 7 (Nek7 Mouse)
   

   Tags

   HA

   Expression

   Mammalian

   Mutation

   Lys 64 mutated to Met; kinase inactive and F236L …

   Promoter

   CMV

   Available Since

   May 19, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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7. Ad:2CMV_A2R2-N25K3

   Plasmid

   #122242

   Purpose

   Expresses a dominant negative Kash construct that disrupts LINC complexes in addition to fluorescently tagged (mRuby2) α-Actinin-2 on an adenoviral backbone

   Depositor

   Corey Neu

   Article

   Seelbinder et al Nat Biomed Eng. 2021 Dec;5(12):1500-1516

   Inserts

   C-terminal end of Nesprin-3 (Syne3 Mouse)
   Actinin alpha 2 (Actn2 Mouse)
   

   Use

   Adenoviral

   Tags

   Signal Peptide (TOR1A, NM_000113.2), mNeptune2.5,…

   Expression

   Mammalian

   Promoter

   CMV

   Available Since

   June 28, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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8. pYX233-b2-DHFR

   Plasmid

   #163759

   Purpose

   Gal-inducible yeast expression of the mitochondrial "clogger" protein b2(167)-DHFR

   Depositor

   Johannes Herrmann

   Article

   Boos et al Nat Cell Biol. 2019 Apr;21(4):442-451. d

   Insert

   b2-DHFR (Dhfr Budding Yeast, Mouse)
   

   Expression

   Yeast

   Mutation

   Amino acids 1-167 of S.c. Cytochrome b2 (Cyb2) fu…

   Promoter

   GAL1

   Available Since

   March 16, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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9. pcDHa_mDDX5_FL_K144N

   Plasmid

   #88870

   Purpose

   constitutive expression of Ha-DDX5 K144N in mammalian cells

   Depositor

   Dan Littman

   Article

   Huang et al Nature. 2015 Dec 24;528(7583):517-22. do

   Insert

   DDX5 (Ddx5 Mouse)
   

   Tags

   HA

   Expression

   Mammalian

   Mutation

   K144N

   Promoter

   CMV

   Available Since

   June 12, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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10. LMP AMPK alpha1 hp1

    Plasmid

    #89489

    Purpose

    shRNA against AMPK alpha1 in mouse/human to knock down protein expression

    Depositor

    Russell Jones

    Article

    Faubert et al Cell Metab. 2013 Jan 8;17(1):113-24. doi

    Insert

    hairpin against mouse/human AMPKalpha1 (PRKAA1, Prkaa1 Mouse, Human)
    

    Use

    Mouse Targeting and Retroviral

    Expression

    Mammalian

    Promoter

    U6 (The GFP-Puro is from a PGK promoter; the shRN…

    Available Since

    May 19, 2017

    Availability

    Academic Institutions and Nonprofits only

11. pcDNA6-N-3XFLAG-Ubxd8

    Plasmid

    #123599

    Depositor

    Bruce Beutler

    Article

    Choi et al Science. 2019 May 10;364(6440). pii: 364

    Insert

    Fas associated factor family member 2 (Faf2 Mouse)
    

    Tags

    FLAG

    Expression

    Mammalian

    Available Since

    July 29, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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12. pAAV-hSyn-DIO {mCAR}off-{DTR-GFP}on-WPRE

    Plasmid

    #111395

    Purpose

    AAV vector with hSynapsin promoter, Cre-OFF mCAR (for efficient CAV-2 infection), Cre-ON DTR-EGFP (diphtheria toxin receptor for cell ablation)

    Depositor

    Adam Kepecs

    Article

    Li et al Neuron. 2018 Jun 6;98(5):905-917.e5. doi

    Inserts

    mCAR (Cxadr Mouse)
    DTR-EGFP
    

    Use

    AAV

    Tags

    EGFP and Myc

    Expression

    Mammalian

    Promoter

    hSynapsin

    Available Since

    June 8, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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13. pCEP4-FLAG-TAPBPR-TM-VC

    Plasmid

    #135499

    Purpose

    Mammalian expression of VC-fused and FLAG-tagged TAPBPR with MHC TM

    Depositor

    Erik Procko

    Article

    McShan et al Proc Natl Acad Sci U S A. 2019 Dec 17;11

    Insert

    TAPBPR (TAPBPL Human)
    

    Tags

    Luminal/Extracellular FLAG epitope tag, Signal pe…

    Expression

    Mammalian

    Mutation

    switched transmembrane domain with that of MHC-I

    Promoter

    CMV

    Available Since

    Feb. 6, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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14. pLgw Cbx1-V5-EcoDam

    Plasmid

    #59211

    Purpose

    Mammalian DamID positive control lentiviral plasmid. Expresses Cbx1-V5-Dam.

    Depositor

    Bas van Steensel

    Article

    Vogel et al Genome Res. 2006 Dec;16(12):1493-504. Ep

    Insert

    Cbx1 (Cbx1 Mouse)
    

    Use

    Lentiviral; Damid

    Tags

    Dam and V5

    Expression

    Mammalian

    Promoter

    Heat Shock Minimal Promoter and heat shock minima…

    Available Since

    June 14, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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15. pCDF-His-mTET1CD∆cat

    Plasmid

    #81054

    Purpose

    bacterial expression of catalytic dead catalytic domain of murine TET1

    Depositor

    Primo Schaer

    Article

    Weber et al Nat Commun. 2016 Mar 2;7:10806. doi: 10.

    Insert

    TET1 (Tet1 Mouse)
    

    Tags

    6HIS

    Expression

    Bacterial

    Mutation

    catalytic domain amino acid 1367-2057 with histid…

    Promoter

    T7

    Available Since

    Aug. 19, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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16. pcDNA3-sACE2v1-Fc(IgG1)

    Plasmid

    #145164

    Purpose

    Mammalian expression plasmid for soluble ACE2-Fc fusion (IgG1) high affinity variant 1

    Depositor

    Erik Procko

    Article

    Chan et al Science. 2020 Sep 4;369(6508):1261-1265.

    Insert

    Angiotensin-converting enzyme 2 (ACE2 Human)
    

    Tags

    Fc region of human IgG1

    Expression

    Mammalian

    Mutation

    Extracellular, soluble protease domain (a.a. M1-D…

    Promoter

    CMV

    Available Since

    April 29, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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17. pLX304_zeo_mmMavs_V5

    Plasmid

    #160100

    Purpose

    Expresses murine Mavs in mammalian cells

    Depositor

    Rizwan Haq

    Article

    Gstalder et al Cancer Discov. 2020 May 5. pii: 2159-829

    Insert

    Mavs (Mavs Mouse)
    

    Use

    Lentiviral

    Tags

    V5

    Expression

    Mammalian

    Available Since

    Oct. 13, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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18. pLJM5-mSHMT2

    Plasmid

    #83905

    Purpose

    stable overexpression

    Depositor

    David Sabatini

    Article

    Pacold et al Nat Chem Biol. 2016 Jun;12(6):452-8. doi

    Insert

    Serine hydroxymethyltransferase 2 (Shmt2 Mouse)
    

    Use

    Lentiviral

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    Oct. 21, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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19. pcDNA3-sACE2v2-Fc(IgG1)

    Plasmid

    #145165

    Purpose

    Mammalian expression plasmid for soluble ACE2-Fc fusion (IgG1) high affinity 2

    Depositor

    Erik Procko

    Article

    Chan et al Science. 2020 Sep 4;369(6508):1261-1265.

    Insert

    Angiotensin-converting enzyme 2 (ACE2 Human)
    

    Tags

    Fc region of human IgG1

    Expression

    Mammalian

    Mutation

    Extracellular, soluble protease domain (a.a. M1-D…

    Promoter

    CMV

    Available Since

    April 15, 2020

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. Lenti-U6-sgMettl3

    Plasmid

    #196263

    Purpose

    Expresses a Mettl3-targeting sgRNA driven by the U6 promoter and Cre-recombinase driven by the PGK promoter

    Depositor

    Laura Attardi

    Article

    Raj et al Mol Cell. 2022 Jul 7;82(13):2370-2384.e1

    Insert

    Mettl3 sgRNA (Mettl3 Mouse)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    U6

    Available Since

    March 16, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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