We narrowed to 926 results for: THY-2

1. pFB1.HMBP.PrS.dEZH2

   Plasmid

   #220241

   Purpose

   Expression of an EZH2 catalytic site mutant in insect cells.

   Depositor

   Chen Davidovich

   Article

   Gail et al Nat Genet. 2024 May 14. doi: 10.1038/s41

   Insert

   dEZH2 (EZH2 Human)
   

   Use

   Tags

   6x His, MBP

   Expression

   Insect

   Mutation

   Y731F

   Promoter

   Polyhedrin

   Available since

   June 12, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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2. pFB1.HMBP.PrS.EZH2-mt1

   Plasmid

   #220239

   Purpose

   Expression of an EZH2 mutant in insect cells.

   Depositor

   Chen Davidovich

   Article

   Gail et al Nat Genet. 2024 May 14. doi: 10.1038/s41

   Insert

   EZH2 mt 1 (EZH2 Human)
   

   Use

   Tags

   6x His, MBP

   Expression

   Insect

   Mutation

   R27A, R31A, F165A

   Promoter

   Polyhedrin

   Available since

   June 12, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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3. pT7C-DNAJB6

   Plasmid

   #177657

   Purpose

   Recombinant protein synthesis of human DNAJB6

   Depositor

   Jeff Kuret

   Article

   Ayoub et al PLoS Genet. 2023 Mar 27;19(3):e1010681.

   Insert

   DNAJB6 (DNAJB6 Human)
   

   Use

   Tags

   6xHis-Thrombin

   Expression

   Bacterial

   Mutation

   Promoter

   T7

   Available since

   Dec. 16, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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4. PM2-FRB-CFP

   Plasmid

   #67518

   Purpose

   FRB conjugated plasma membrane targeting sequences 2 from Lyn11(GCIKSKGKDSA)

   Depositor

   Tamas Balla

   Article

   Varnai et al J Cell Biol. 2006 Nov 6;175(3):377-82.

   Insert

   mTOR (MTOR Human)
   

   Use

   Tags

   CFP, HA, and PM tethering sequence from human Lyn…

   Expression

   Mammalian

   Mutation

   FRB domain only (residues 2019–2114)

   Promoter

   CMV

   Available since

   Aug. 25, 2015

   Availability

   Academic Institutions and Nonprofits only

5. pT7II-2N4Rtau

   Plasmid

   #177653

   Purpose

   Recombinant protein synthesis of human Tau

   Depositor

   Jeff Kuret

   Article

   Ayoub et al PLoS Genet. 2023 Mar 27;19(3):e1010681.

   Insert

   Tau (2N4R) (MAPT Human)
   

   Use

   Tags

   Expression

   Bacterial

   Mutation

   Promoter

   T7

   Available since

   Dec. 16, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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6. FH-Tet2-pEF

   Plasmid

   #41710

   Purpose

   This plasmid expresses mouse Tet2 with N-terminal FLAG and HA tags in a mammalian system

   Depositor

   Anjana Rao

   Article

   Ko et al Nature. 2010 Dec 9;468(7325):839-43. doi

   Insert

   tet methylcytosine dioxygenase 2 (Tet2 Mouse)
   

   Use

   Tags

   FLAG and HA

   Expression

   Mammalian

   Mutation

   Promoter

   EF1a

   Available since

   Feb. 18, 2014

   Availability

   Academic Institutions and Nonprofits only

   

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7. MLM3709

   Plasmid

   #49943

   Purpose

   Expresses a 3x Flag TALE-TET1CD (catalytic domain of TET1) fusion protein engineered to bind a site in the human RHOXF2/2B homeobox (RHOXF2) gene and demethylate CpGs adjacent to the binding site

   Depositor

   Keith Joung

   Article

   Maeder et al Nat Biotechnol. 2013 Oct 9. doi: 10.1038

   Insert

   3x FLAG Tet1CD RH-3 (RHOXF2 Human)
   

   Use

   TALEN

   Tags

   3x FLAG

   Expression

   Mutation

   Promoter

   EF1a

   Available since

   Dec. 20, 2013

   Availability

   Academic Institutions and Nonprofits only

8. MLM3713

   Plasmid

   #49946

   Purpose

   Expresses a 3x Flag TALE-TET1CD (catalytic domain of TET1) fusion protein engineered to bind a site in the human RHOXF2/2B homeobox (RHOXF2) gene and demethylate CpGs adjacent to the binding site

   Depositor

   Keith Joung

   Article

   Maeder et al Nat Biotechnol. 2013 Oct 9. doi: 10.1038

   Insert

   3x FLAG Tet1CD RH-4 (RHOXF2 Human)
   

   Use

   TALEN

   Tags

   3x FLAG

   Expression

   Mutation

   Promoter

   EF1a

   Available since

   Dec. 31, 2013

   Availability

   Academic Institutions and Nonprofits only

9. Mouse GFP-PRMT7 LDIG(69-72)AAAA

   Plasmid

   #65044

   Purpose

   Expresses Catalytically inactive GFP-PRMT7 LDIG(69-72)AAAA mutant

   Depositor

   Steven Clarke

   Article

   Feng et al J Biol Chem. 2013 Dec 27;288(52):37010-2

   Insert

   PRMT7 (Prmt7 Mouse)
   

   Use

   Bacterial propagation

   Tags

   GFP

   Expression

   Mammalian

   Mutation

   L69A D70A I71A G72A

   Promoter

   CMV

   Available since

   July 8, 2015

   Availability

   Academic Institutions and Nonprofits only

10. pGhMeCP2 (pc3972)

    Plasmid

    #212033

    Purpose

    Expresses human MeCP2 tagged N-terminal to Halo-tag

    Depositor

    Cristina Cardoso

    Article

    Zhang et al Nucleus. 2022 Dec;13(1):1-34. doi: 10.10

    Insert

    MeCP2 (MECP2 Human)
    

    Use

    Tags

    GFP

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    July 11, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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11. pMXs-Sox2AV

    Plasmid

    #193354

    Purpose

    Retroviral vector expressing mouse Sox2A61V point mutant

    Depositor

    Hans Schöler

    Article

    MacCarthy et al Cell Stem Cell. 2024 Jan 4;31(1):127-147

    Insert

    Sox2AV (Sox2 Mouse)
    

    Use

    Retroviral

    Tags

    Expression

    Mammalian

    Mutation

    Sox2A61V is a highly cooperative point mutant of …

    Promoter

    5'LTR

    Available since

    Dec. 15, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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12. pSLQ9757: CMV-BPNLS_TadA-linkerA-TadA*(8e)-Linker B-SV40 NLS-dCasMINI-V4-linkerC-c-Myc_NLS-3x FLAG-polyA

    Plasmid

    #176270

    Purpose

    Expression of TadA-TadA* (8e)-dCasMINI-V4 in mammalian cells

    Depositor

    Stanley Qi

    Article

    Xu et al Mol Cell. 2021 Aug 26. pii: S1097-2765(2

    Insert

    TadA-TadA*(8e)-dCasMINI-V4
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    Oct. 1, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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13. pGL4.10-Claudin-1

    Plasmid

    #46387

    Purpose

    Claudin-1 promoter reporter assay

    Depositor

    David Mu

    Article

    Runkle et al J Biol Chem. 2012 Aug 17;287(34):28790-8

    Insert

    CLDN1 Promoter (CLDN1 Human)
    

    Use

    Luciferase

    Tags

    Expression

    Mutation

    Promoter

    CLDN1 promoter

    Available since

    Aug. 2, 2013

    Availability

    Academic Institutions and Nonprofits only

14. lentiCRISPRv2-TTF-1-gRNA

    Plasmid

    #101857

    Purpose

    Introducing a gRNA targeting human TTF-1 (NKX2-1) into cells

    Depositor

    David Mu

    Article

    Lai et al Oncogene. 2018 Mar 19. pii: 10.1038/s413

    Insert

    gRNA targeting TTF-1 (NKX2-1 Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available since

    Oct. 25, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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15. pMSCV-puro-TTF-1-HDD

    Plasmid

    #74991

    Purpose

    Retroviral vector holding human TTF-1 (NKX2-1) with the homeodomain deleted

    Depositor

    David Mu

    Article

    Wood et al Sci Rep. 2016 Feb 25;6:19857. doi: 10.10

    Insert

    TTF-1 HDD mutant (NKX2-1 Human)
    

    Use

    Retroviral

    Tags

    None

    Expression

    Mammalian

    Mutation

    HDD = homeodomain deleted

    Promoter

    Available since

    July 27, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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16. hnRNPAB X2-RBD

    Plasmid

    #216516

    Purpose

    Expresses MBP-tagged RNA binding domain of hnRNPAB X2

    Depositor

    Nicolas Fawzi

    Article

    O'Connell et al Sci Rep. 2024 Nov 13;14(1):27890. doi: 1

    Insert

    hnRNPAB X2-RBD
    

    Use

    Tags

    6xHis tags-MBP

    Expression

    Bacterial

    Mutation

    deleted amino acids 2-64 and 226-304

    Promoter

    Available since

    Dec. 18, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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17. Puro-TTL-TTF-1-HDD

    Plasmid

    #74989

    Purpose

    Human TTF-1 (NKX2-1) cDNA with the homeodomain deleted

    Depositor

    David Mu

    Article

    Wood et al Sci Rep. 2016 Feb 25;6:19857. doi: 10.10

    Insert

    TTF-1 HDD mutant (NKX2-1 Human)
    

    Use

    Retroviral

    Tags

    Expression

    Mammalian

    Mutation

    Homeodomain

    Promoter

    Available since

    Aug. 10, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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18. RG9MTD2

    Plasmid

    #40742

    Purpose

    Bacterial expression for structure determination; may not be full ORF

    Depositor

    Cheryl Arrowsmith

    Insert

    RG9MTD2 (TRMT10A Human)
    

    Use

    Tags

    6xHis TEV

    Expression

    Bacterial

    Mutation

    Promoter

    Available since

    Oct. 18, 2012

    Availability

    Industry, Academic Institutions, and Nonprofits

19. pLVTHM-mSox2-3xflag

    Plasmid

    #206376

    Purpose

    Expresses 3xflag fused mouse SOX2 in mammalian cells, for lentivirus generation.

    Depositor

    Ralf Jauch

    Article

    Hu et al Nucleic Acids Res. 2023 Aug 23:gkad597.

    Insert

    Sox2 (Sox2 Mouse)
    

    Use

    Lentiviral

    Tags

    3xFLAG

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Oct. 6, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. pHAGE2-TetO-GFP-mSox2

    Plasmid

    #206374

    Purpose

    Expresses EGFP fused mouse SOX2 in mammalian cells, for lentivirus generation.

    Depositor

    Ralf Jauch

    Article

    Hu et al Nucleic Acids Res. 2023 Aug 23:gkad597.

    Insert

    Sox2 (Sox2 Mouse)
    

    Use

    Lentiviral

    Tags

    EGFP

    Expression

    Mutation

    Promoter

    Available since

    Oct. 6, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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