We narrowed to 18,339 results for: Mut

1. pBacMam2-DiEx-LIC-C-flag_huntingtin_full-length_Q66

   Plasmid

   #111750

   Purpose

   Baculovirus transfer vector for expression of huntingtin protein in insect and mammalian cellscells as well as in mammalian cells

   Depositor

   Cheryl Arrowsmith

   Article

   Harding et al J Biol Chem. 2019 Apr 26;294(17):6986-70

   Insert

   HTT (HTT Human)
   

   Use

   Baculovirus expression

   Tags

   FLAG

   Expression

   Mammalian

   Mutation

   Q66 (polyQ repeat)

   Promoter

   CMV and P10

   Available Since

   Nov. 1, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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2. pLenti CMV TRE3G Neo GFP-Progerin C661S

   Plasmid

   #118711

   Purpose

   Lentiviral TET-ON inducible GFP-Progerin C661S (Farnesylation mutant)

   Depositor

   Tom Misteli

   Article

   Kubben et al Methods. 2015 Sep 1. pii: S1046-2023(15)

   Insert

   GFP-Progerin C661S (LMNA Human)
   

   Use

   Lentiviral; Tet-on inducible

   Tags

   GFP

   Expression

   Mammalian

   Mutation

   C661S farnesylation mutant

   Promoter

   CMV TRE3G (TET-ON)

   Available Since

   Nov. 21, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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3. pcdna6.2- myc ULK1 k46I

   Plasmid

   #27630

   Depositor

   Reuben Shaw

   Article

   Egan et al Science. 2011 Jan 28;331(6016):456-61. d

   Insert

   mouse myc ULK1 K46I (Myc Mouse)
   

   Use

   Tags

   myc

   Expression

   Mammalian

   Mutation

   Initial M from ULK1 removed. Silent mutation at A…

   Promoter

   Available Since

   Feb. 18, 2011

   Availability

   Academic Institutions and Nonprofits only

4. pBacMam2-DiEx-LIC-N-flag_huntingtin_full-length_Q73

   Plasmid

   #111724

   Purpose

   Baculovirus transfer vector for expression of huntingtin protein in insect and mammalian cellscells as well as in mammalian cells

   Depositor

   Cheryl Arrowsmith

   Article

   Harding et al J Biol Chem. 2019 Apr 26;294(17):6986-70

   Insert

   HTT (HTT Human)
   

   Use

   Baculovirus expression

   Tags

   FLAG

   Expression

   Mammalian

   Mutation

   Q73 (polyQ repeat)

   Promoter

   CMV and P10

   Available Since

   Nov. 1, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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5. CMV-NanoLuc-BRAF-CAT

   Plasmid

   #194772

   Purpose

   Mammalian expression construct encoding the BRAF catalytic (CAT) domain (AA 435-766) with an N-terminal NanoLuc tag.

   Depositor

   Deborah Morrison

   Article

   Spencer-Smith et al Mol Cell. 2022 Nov 17;82(22):4262-4276.e

   Insert

   BRAF catalytic (CAT) domain (AA 435-766) (BRAF Human)
   

   Use

   Tags

   NanoLuc

   Expression

   Mammalian

   Mutation

   Promoter

   CMV51

   Available Since

   June 20, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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6. CMV-BRAF-REG-Halo

   Plasmid

   #194771

   Purpose

   Mammalian expression construct encoding the BRAF regulatory (REG) domain (AA 1-435) with a C-terminal HaloTag.

   Depositor

   Deborah Morrison

   Article

   Spencer-Smith et al Mol Cell. 2022 Nov 17;82(22):4262-4276.e

   Insert

   BRAF regulatory (REG) domain (AA 1-435) (BRAF Human)
   

   Use

   Tags

   HaloTag

   Expression

   Mammalian

   Mutation

   Promoter

   CMV51

   Available Since

   Feb. 8, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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7. XLone-Puro beta-catenin P2A eGFP-NLS

   Plasmid

   #155189

   Purpose

   PiggybacTransposon-based tunable and temporal expression control of mutated beta-catenin and nuclear eGFP

   Depositor

   Xiaoping Bao

   Article

   Chang et al Biomaterials. 2022 May 6;285:121569. doi

   Insert

   beta-catenin (Ctnnb1 Mouse)
   

   Use

   Unspecified; Piggybac transposon

   Tags

   P2A eGFP NLS

   Expression

   Mammalian

   Mutation

   Sites phosphorylated by GSK-3beta have been mutat…

   Promoter

   TRE3G

   Available Since

   June 24, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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8. pBacMam2-DiEx-LIC-C-flag_huntingtin_full-length_Q73

   Plasmid

   #111728

   Purpose

   Baculovirus transfer vector for expression of huntingtin protein in insect and mammalian cellscells as well as in mammalian cells

   Depositor

   Cheryl Arrowsmith

   Article

   Harding et al J Biol Chem. 2019 Apr 26;294(17):6986-70

   Insert

   HTT (HTT Human)
   

   Use

   Baculovirus expression

   Tags

   FLAG

   Expression

   Mammalian

   Mutation

   Q73 (polyQ repeat)

   Promoter

   CMV and P10

   Available Since

   Oct. 31, 2018

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

9. pHAGE-SMO

   Plasmid

   #116792

   Purpose

   Lentiviral expression of SMO

   Depositor

   Gordon Mills, Kenneth Scott

   Article

   Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

   Insert

   SMO (SMO Human)
   

   Use

   Lentiviral

   Tags

   Expression

   Mutation

   WT

   Promoter

   Available Since

   March 14, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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10. pAAV-CMVenh synapsin-intron-aSYNUCLEIN A53T

    Plasmid

    #227004

    Purpose

    AAV transfer plasmid encoding the human A53T mutant α-SYN under the control of the CMVie enhanced synapsin1 promoter

    Depositor

    Veerle Baekelandt

    Article

    Van der Perren et al J Vis Exp. 2016 Feb 28;(108):53670. doi:

    Insert

    alpha synuclein A53T mutant (SNCA Synthetic, Human)
    

    Use

    AAV

    Tags

    Expression

    Mutation

    A53T

    Promoter

    CMVenh synapsin

    Available Since

    Oct. 31, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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11. pHAGE-PDGFRA-Y288C

    Plasmid

    #116453

    Purpose

    Lentiviral expression of PDGFRA Y288C

    Depositor

    Gordon Mills, Kenneth Scott

    Article

    Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

    Insert

    PDGFRA (PDGFRA Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    Y288C

    Promoter

    Available Since

    March 14, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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12. pHAGE-BRAF-G596S

    Plasmid

    #116159

    Purpose

    Lentiviral expression of BRAF G596S

    Depositor

    Gordon Mills, Kenneth Scott

    Article

    Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

    Insert

    BRAF (BRAF Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    G596S

    Promoter

    Available Since

    March 14, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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13. pDONR223_ARAF_WT

    Plasmid

    #82900

    Purpose

    Gateway Donor vector containing ARAF, part of the Target Accelerator Plasmid Collection.

    Depositor

    Matthew Meyerson, Jesse Boehm, David Root

    Article

    Berger et al Cancer Cell. 2016 Aug 8;30(2):214-28. do

    Insert

    NM_001654 (ARAF Human)
    

    Use

    Gateway entry vector

    Tags

    Expression

    Mutation

    Promoter

    None

    Available Since

    April 24, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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14. pHAGE-EGFR-G719A

    Plasmid

    #116253

    Purpose

    Lentiviral expression of EGFR G719A

    Depositor

    Gordon Mills, Kenneth Scott

    Article

    Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

    Insert

    EGFR (EGFR Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    G719A

    Promoter

    Available Since

    March 14, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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15. pHAGE-GUCY2C

    Plasmid

    #116749

    Purpose

    Lentiviral expression of GUCY2C

    Depositor

    Gordon Mills, Kenneth Scott

    Article

    Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

    Insert

    GUCY2C (GUCY2C Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    WT

    Promoter

    Available Since

    March 14, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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16. sgTP53(A)

    Plasmid

    #85559

    Purpose

    Expresses sgRNA targeting human TP53 around codon F109

    Depositor

    Luca Grumolato

    Article

    Guernet et al Mol Cell. 2016 Aug 4;63(3):526-38. doi:

    Insert

    tumor protein p53 (TP53 Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available Since

    Feb. 8, 2017

    Availability

    Academic Institutions and Nonprofits only

17. pDONR223_TERT_p.L593F

    Plasmid

    #82856

    Purpose

    Gateway Donor vector containing TERT, part of the Target Accelerator Plasmid Collection.

    Depositor

    Matthew Meyerson, Jesse Boehm, David Root

    Article

    Berger et al Cancer Cell. 2016 Aug 8;30(2):214-28. do

    Insert

    TERT (TERT Human)
    

    Use

    Gateway entry vector

    Tags

    Expression

    Mutation

    D516G, L593F

    Promoter

    None

    Available Since

    April 24, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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18. pHAGE-AKT3

    Plasmid

    #116711

    Purpose

    Lentiviral expression of AKT3

    Depositor

    Gordon Mills, Kenneth Scott

    Article

    Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

    Insert

    AKT3 (AKT3 Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    WT

    Promoter

    Available Since

    March 14, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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19. TRIPZ-bioGEF-SUMO1nc-PURO

    Plasmid

    #208042

    Purpose

    Enables inducible expression of low-affinity Avitag-SUMO1nc; to perform bioE3; nc = non-cleavable mutation; selection with puromycin

    Depositor

    James Sutherland, Rosa Barrio

    Article

    Barroso-Gomila et al Nat Commun. 2023 Nov 23;14(1):7656. doi:

    Insert

    SUMO1nc (SUMO1 Human)
    

    Use

    Lentiviral

    Tags

    Low-affinity Avitag

    Expression

    Mutation

    Q94P Mutation near C-terminus suppresses cleavage…

    Promoter

    tetO/UBC

    Available Since

    Nov. 29, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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20. pHAGE-MAP2K1-K57N

    Plasmid

    #116427

    Purpose

    Lentiviral expression of MAP2K1 K57N

    Depositor

    Gordon Mills, Kenneth Scott

    Article

    Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

    Insert

    MAP2K1 (MAP2K1 Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    K57N

    Promoter

    Available Since

    March 14, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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