We narrowed to 2,779 results for: SAB

1. prk5-MFSD12-TEV-3xFLAG-3xHA

   Plasmid

   #149504

   Purpose

   Transient expression of human MFSD12 with recoded nucleotide sequence.

   Depositor

   David Sabatini

   Article

   Adelmann et al Nature. 2020 Nov 18. pii: 10.1038/s41586

   Insert

   MFSD12 (MFSD12 Human)
   

   Use

   Transient expression

   Tags

   TEV-3XHA-3XFLAG

   Expression

   Mammalian

   Mutation

   Codon Optimized Sequence

   Promoter

   CMV

   Available Since

   Nov. 19, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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2. pIS1-Vim/Actb5UTR-renilla

   Plasmid

   #38238

   Depositor

   David Sabatini

   Article

   Thoreen et al Nature. 2012 May 2;485(7396):109-13. doi

   Insert

   Vim promoter with Actb 5UTR/Renilla (Vim, Actb Mouse)
   

   Use

   Luciferase

   Expression

   Mammalian

   Mutation

   Actb promoter (1000 nt upstream) and 5' UTR …

   Promoter

   Endogenous Vim

   Available Since

   Nov. 7, 2012

   Availability

   Academic Institutions and Nonprofits only

3. pLenti-sgRELA

   Plasmid

   #83944

   Purpose

   Lentiviral vector expressing an sgRNA targeting RELA NOTE: This plasmid does NOT contain Cas9.

   Depositor

   David Sabatini

   Article

   Park et al Nat Genet. 2016 Dec 19. doi: 10.1038/ng.

   Insert

   sgRELA
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   U6

   Available Since

   Feb. 1, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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4. pMXs2-RAC1

   Plasmid

   #86138

   Purpose

   Retrolviral vector expressing RAC1-IRES-Bsd-p2A-RFP

   Depositor

   David Sabatini

   Article

   Wang et al Cell. 2017 Feb 1. pii: S0092-8674(17)300

   Insert

   RAC1 (RAC1 Human)
   

   Use

   Retroviral

   Tags

   3xFLAG

   Expression

   Mammalian

   Available Since

   Feb. 22, 2017

   Availability

   Academic Institutions and Nonprofits only

5. pLJM5-mDPYD

   Plasmid

   #61614

   Purpose

   The mouse Dpyd was used to rescue the human DPYD hairpin affect on EMT

   Depositor

   David Sabatini

   Article

   Shaul et al Cell. 2014 Aug 28;158(5):1094-109. doi:

   Insert

   dihydropyrimidine dehydrogenase (Dpyd Mouse)
   

   Expression

   Mammalian

   Promoter

   CMV

   Available Since

   Jan. 20, 2015

   Availability

   Academic Institutions and Nonprofits only

   

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6. pMXs-HA-C1orf27

   Plasmid

   #86122

   Purpose

   Retroviral vector expressing HA-C1orf27-IRES-Bsd

   Depositor

   David Sabatini

   Article

   Wang et al Cell. 2017 Feb 1. pii: S0092-8674(17)300

   Insert

   C1orf27 (C1orf27 Human)
   

   Use

   Retroviral

   Tags

   HA

   Expression

   Mammalian

   Promoter

   LTR

   Available Since

   Feb. 22, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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7. prk5-TMEM192-3xHA PM mutant

   Plasmid

   #149506

   Purpose

   Transient expression of human TMEM192. Dileucine motifs LL23-24 and LL28-29 have been mutated to AA.

   Depositor

   David Sabatini

   Article

   Adelmann et al Nature. 2020 Nov 18. pii: 10.1038/s41586

   Insert

   TMEM192 (TMEM192 Human)
   

   Use

   Transient expression

   Tags

   3XHA

   Expression

   Mammalian

   Mutation

   p.LL23-24AA, p.LL28-29AA

   Promoter

   CMV

   Available Since

   Jan. 26, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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8. LentiCRISPR-sgSHOC2-1

   Plasmid

   #86128

   Purpose

   Lentiviral vector expressing Cas9 and an sgRNA targeting SHOC2

   Depositor

   David Sabatini

   Article

   Wang et al Cell. 2017 Feb 1. pii: S0092-8674(17)300

   Insert

   sgRNA 1 targeting SHOC2 (SHOC2 )
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   U6

   Available Since

   Feb. 22, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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9. pAAV-Ef1a-FAS-ChETA-TdTomato-WPRE-pA

   Plasmid

   #37089

   Purpose

   Expresses ChETA-tdTomato in cells lacking Cre (Cre-Off, flanked by alternative lox FAS sites), for optogenetic excitation

   Depositor

   Bernardo Sabatini

   Article

   Saunders et al Front Neural Circuits. 2012 Jul 27;6:47.

   Insert

   ChETA-TdTomato
   

   Use

   AAV and Cre/Lox; Cre-off

   Tags

   TdTomato

   Promoter

   EF1a

   Available Since

   July 27, 2012

   Availability

   Academic Institutions and Nonprofits only

   

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10. LentiCRISPR-sgSHOC2-2

    Plasmid

    #86129

    Purpose

    Lentiviral vector expressing Cas9 and an sgRNA targeting SHOC2

    Depositor

    David Sabatini

    Article

    Wang et al Cell. 2017 Feb 1. pii: S0092-8674(17)300

    Insert

    sgRNA 2 targeting SHOC2 (SHOC2 )
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Available Since

    May 15, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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11. pDIV494

    Plasmid

    #177701

    Purpose

    Plasmid expressing optimized Cas9 and NAT marker and sgRNA targeting ADE2 locus in D. hansenii

    Depositor

    Uffe Mortensen

    Article

    Strucko et al Synth Biol (Oxf). 2021 Oct 12;6(1):ysab0

    Inserts

    Cas9
    Nat
    sgRNA Targeting ADE2 locus in D.hansenii: AGCTAAGCAGATTAATGCAT
    

    Use

    CRISPR

    Tags

    SV40

    Expression

    Bacterial and Yeast

    Promoter

    RNR2p (Debaryomyces hansenii ), SNR52p (Candida s…

    Available Since

    March 11, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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12. [pSK483] pLJC5 Flag-Depdc5(P)

    Plasmid

    #109342

    Purpose

    Lenti-viral expression of Flag-tagged Depdc5 mutant P

    Depositor

    David Sabatini, Kuang Shen

    Article

    Shen et al Nature. 2018 Apr 5;556(7699):64-69. doi:

    Insert

    Depdc5 (DEPDC5 Human)
    

    Use

    Lentiviral

    Tags

    FLAG

    Mutation

    YDLLP(775-779)GSGSG

    Available Since

    July 24, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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13. shGLDC-DOX

    Plasmid

    #72883

    Purpose

    dox inducible knockdown

    Depositor

    David Sabatini

    Article

    Kim et al Nature. 2015 Apr 16;520(7547):363-7. doi

    Insert

    RNAi hairpin against GLDC
    

    Use

    Lentiviral

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    Feb. 12, 2016

    Availability

    Academic Institutions and Nonprofits only

14. pcDNA3-FLAG-MTOR-D2512H

    Plasmid

    #69017

    Purpose

    activating MTOR mutation

    Depositor

    David Sabatini

    Article

    Grabiner et al Cancer Discov. 2014 May;4(5):554-63. doi

    Insert

    MTOR-D2512H (MTOR Human)
    

    Tags

    FLAG

    Expression

    Mammalian

    Mutation

    change Aspartate 2512 to Histidine

    Available Since

    Dec. 16, 2015

    Availability

    Academic Institutions and Nonprofits only

15. pAAV-Ef1a-FAS-NpHR3.0-eYFP-WPRE-pA

    Plasmid

    #37088

    Purpose

    Expresses NpHR3.0-EYFP in cells lacking Cre (Cre-Off, flanked by alternative lox FAS sites), for optogenetic inhibition

    Depositor

    Bernardo Sabatini

    Article

    Saunders et al Front Neural Circuits. 2012 Jul 27;6:47.

    Insert

    NpHR3.0-EYFP
    

    Use

    AAV and Cre/Lox; Cre-off

    Tags

    EYFP

    Promoter

    EF1a

    Available Since

    July 27, 2012

    Availability

    Academic Institutions and Nonprofits only

    

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16. FusXTBE-1397-C

    Plasmid

    #201398

    Purpose

    Expresses C terminus half of DddAtox in mammalian cells

    Depositor

    Stephen Ekker

    Article

    Sabharwal et al CRISPR J. 2021 Dec;4(6):799-821. doi: 10

    Insert

    COX8A MTS-LacZ-G1397 DddAtox-C-UGI-ATP5B 3'UTR
    

    Expression

    Mammalian

    Available Since

    June 14, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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17. FusXTBE-1397-N

    Plasmid

    #201397

    Purpose

    Expresses N terminus half of DddAtox in mammalian cells

    Depositor

    Stephen Ekker

    Article

    Sabharwal et al CRISPR J. 2021 Dec;4(6):799-821. doi: 10

    Insert

    COX8A MTS-LacZ-G1397 DddAtox-N-UGI-ATP5B 3'UTR
    

    Expression

    Mammalian

    Available Since

    June 14, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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18. [pSK496] pLJC5 HA-Depdc5(AB)

    Plasmid

    #109346

    Purpose

    Lenti-viral expression of HA-tagged Depdc5 mutant AB

    Depositor

    David Sabatini, Kuang Shen

    Article

    Shen et al Nature. 2018 Apr 5;556(7699):64-69. doi:

    Insert

    Depdc5 (DEPDC5 Human)
    

    Use

    Lentiviral

    Tags

    HA

    Mutation

    DIYGD(185-189)GSGSG;EQPLH(371-375)GSGSG

    Available Since

    July 24, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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19. kiCAP-AAV-PAL2

    Plasmid

    #196691

    Purpose

    Rep/Cap plasmid for the production of PAL2, an AAV capsid with CNS tropism in macaques.

    Depositor

    Pardis Sabeti

    Article

    Stanton et al Med (N Y). 2022 Nov 15:S2666-6340(22)004

    Insert

    AAV9 VP1 modified with 7mer insertion between amino acids 588 and 589
    

    Use

    AAV

    Mutation

    PTQGTVR insert between amino acids 588 and 589 of…

    Promoter

    p41

    Available Since

    April 7, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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20. pLKO human shRNA 1 c-MAF

    Plasmid

    #29432

    Depositor

    David Sabatini

    Article

    Peterson et al Cell. 2009 May 29;137(5):873-86. doi: 10

    Insert

    c-MAF shRNA 1 (MAF Human)
    

    Use

    Lentiviral and RNAi

    Expression

    Mammalian

    Available Since

    April 7, 2011

    Availability

    Academic Institutions and Nonprofits only