We narrowed to 18,501 results for: MUT

1. Lenti-N1303K-ngRNA+14_EF1a-puroR

   Plasmid

   #207359

   Purpose

   Lentiviral transfer plasmid encoding hU6-driven expression of a ngRNA for correction of N1303K-CFTR via prime editing and EF1a-driven puromycin resistance gene.

   Depositor

   Marianne Carlon

   Article

   Bulcaen et al Cell Rep Med. 2024 May 21;5(5):101544. d

   Insert

   N1303K-CFTR +14 ngRNA
   

   Use

   Lentiviral

   Available Since

   April 19, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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2. Lenti-L227R-ngRNA+15_EF1a-puroR

   Plasmid

   #207360

   Purpose

   Lentiviral transfer plasmid encoding hU6-driven expression of a ngRNA for correction of L227R-CFTR via prime editing and EF1a-driven puromycin resistance gene.

   Depositor

   Marianne Carlon

   Article

   Bulcaen et al Cell Rep Med. 2024 May 21;5(5):101544. d

   Insert

   L227R-CFTR +15 ngRNA
   

   Use

   Lentiviral

   Available Since

   April 19, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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3. sh2g-ZMYND8-human

   Plasmid

   #201406

   Purpose

   Knockdown of Zinc Finger MYND Type-8. Construct has inverted repeats to be used in Sleeping Beauty transposon system.

   Depositor

   Maria Castro

   Article

   Carney et al Clin Cancer Res. 2023 Jan 24:CCR-22-1896

   Insert

   ZMYND8 (ZMYND8 Human)
   

   Expression

   Mammalian

   Available Since

   Aug. 9, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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4. sh4p-ZMYND8-mouse

   Plasmid

   #201405

   Purpose

   Knockdown of Zinc Finger MYND Type-8. Construct has inverted repeats to be used in Sleeping Beauty transposon system.

   Depositor

   Maria Castro

   Article

   Carney et al Clin Cancer Res. 2023 Jan 24:CCR-22-1896

   Insert

   ZMYND8
   

   Expression

   Mammalian

   Available Since

   Aug. 9, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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5. pFB-CG-LYCHOS FP>IA-HA-GFP

   Plasmid

   #199688

   Purpose

   Expression of LYCHOS FP>IA mutant in insect cells

   Depositor

   Roberto Zoncu

   Article

   Shin et al Science. 2022 Sep 16;377(6612):1290-1298

   Insert

   LYCHOS (GPR155 Human)
   

   Tags

   10xHis, 6xHis, EGFP, HA, and HRV 3C

   Expression

   Insect

   Mutation

   F43 and P44 mutated to I and A respectively

   Available Since

   May 17, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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6. pD649-HAsp-CD4-Fc(DAPA)-AviTag-6xHis

   Plasmid

   #156808

   Purpose

   Mammalian expression of cell-surface protein extracellular domain fused to Fc(DAPA)-Avi-6xHis. Protein is secreted from cells.

   Depositor

   Chris Garcia

   Article

   Wojtowicz et al Cell. 2020 Aug 20;182(4):1027-1043.e17.

   Insert

   CD4 (CD4 Human)
   

   Tags

   Fc(DAPA)-AviTag-6xHis

   Expression

   Mammalian

   Mutation

   Fc region of human IgG contains D265A and P329A m…

   Promoter

   CMV/SP6

   Available Since

   March 8, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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7. pInducer 21-3xFlag-hMEFV-ΔPYD

   Plasmid

   #195478

   Purpose

   pInducer21 plasmid containing the human MEFV gene with a deletion of residues 1 - 92 (the resulting pyrin protein lacks the PYD domain) with a 3xFlag tag at the N-terminus

   Depositor

   Thomas Henry

   Article

   Chirita et al Cell Death Dis. 2023 Mar 25;14(3):213. d

   Insert

   MEFV (MEFV Human)
   

   Use

   Lentiviral

   Tags

   3xFlag

   Expression

   Mammalian

   Mutation

   deletion of residues 1-92 of pyrin (the PYD domai…

   Available Since

   March 7, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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8. Tet-inducible 3xFlag Mouse C325A Caspase-9 ΔCARD

   Plasmid

   #194608

   Purpose

   Inducible Expression of N-Terminal 3X Flag Mouse C325A Caspase-9 Mutant Minus CARD Domain

   Depositor

   Hannah Rabinowich

   Article

   Han et al J Biol Chem. 2014 Mar 7;289(10):6485-649

   Insert

   N-Terminal 3X Flag Mouse C325A Caspase-9 Mutant Minus Sequence Encoding Met 1 to Lys 176 (Casp9 Mouse)
   

   Tags

   3X Flag

   Expression

   Mammalian

   Mutation

   Deletion of N-terminal CARD domain and changed Cy…

   Promoter

   CMV

   Available Since

   Feb. 17, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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9. pMXS-IRES-BLAST flag-CAD G-Loop1

   Plasmid

   #188128

   Purpose

   Expresses C-terminal flag-tagged human CAD G-Loop1 in mammalian cells

   Depositor

   Richard Possemato

   Article

   Shin et al Nat Metab. 2023 Feb 6. doi: 10.1038/s422

   Insert

   CAD (CAD Human)
   

   Use

   Retroviral

   Tags

   Flag tag

   Expression

   Mammalian

   Mutation

   TCC -> AGT silent mutations at nt439-441 elimi…

   Available Since

   Feb. 6, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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10. pMXS-IRES-BLAST flag-CAD G-Loop2

    Plasmid

    #188129

    Purpose

    Expresses C-terminal flag-tagged human CAD G-Loop2 in mammalian cells

    Depositor

    Richard Possemato

    Article

    Shin et al Nat Metab. 2023 Feb 6. doi: 10.1038/s422

    Insert

    CAD (CAD Human)
    

    Use

    Retroviral

    Tags

    Flag tag

    Expression

    Mammalian

    Mutation

    TCC -> AGT silent mutations at nt439-441 elimi…

    Available Since

    Feb. 6, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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11. mGFP-hNET-A457P

    Plasmid

    #193365

    Purpose

    expression of mutated human norpinephrine transporter tagged with monomeric GFP at the N-terminus in mammalian cells

    Depositor

    Harald Sitte

    Article

    Luethi et al Commun Biol. 2022 Nov 17;5(1):1259. doi:

    Insert

    human Norepinephrine Transporter (A457P mutation) (SLC6A2 Human)
    

    Tags

    monomeric GFP (mGFP)

    Expression

    Mammalian

    Mutation

    A457P (GCC to CCC)

    Promoter

    CMV

    Available Since

    Jan. 9, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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12. pT7-EGFP-C1-HsNot1iso1-del1097-1110-NF1144AA-shRNAres_W

    Plasmid

    #147898

    Purpose

    Mammalian Expression of HsNot1iso1-del1097-1110-NF1144AA-shRNAres

    Depositor

    Elisa Izaurralde

    Article

    Chen et al Mol Cell. 2014 Jun 5;54(5):737-50. doi:

    Insert

    HsNot1iso1-del1097-1110-NF1144AA-shRNAres (CNOT1 Human)
    

    Expression

    Mammalian

    Mutation

    1 silent mutation and one non silent mutation R23…

    Available Since

    Nov. 1, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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13. pT7-EGFP-C1-HsNot1iso1-del1097-1110-R1138A-shRNAres_W

    Plasmid

    #147899

    Purpose

    Mammalian Expression of HsNot1iso1-del1097-1110-R1138A-shRNAres

    Depositor

    Elisa Izaurralde

    Article

    Chen et al Mol Cell. 2014 Jun 5;54(5):737-50. doi:

    Insert

    HsNot1iso1-del1097-1110-R1138A-shRNAres (CNOT1 Human)
    

    Expression

    Mammalian

    Mutation

    1 silent mutation and one non silent mutation R23…

    Available Since

    Nov. 1, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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14. pCMV6-Entry-EPHX1c.337T>C-Flag

    Plasmid

    #169169

    Purpose

    Expresses EPHX1 c.337T>C in mammalian cells

    Depositor

    Bruno Feve, Jeremie Gautheron

    Article

    Gautheron et al Elife. 2021 Aug 3;10. pii: 68445. doi: 1

    Insert

    epoxide hydrolase 1 (EPHX1 Human)
    

    Tags

    Flag

    Expression

    Mammalian

    Mutation

    c.337T>C

    Promoter

    CMV

    Available Since

    Oct. 7, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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15. pCMV6-Entry-EPHX1c.416A>G-Flag

    Plasmid

    #169170

    Purpose

    Expresses EPHX1 c.416A>G in mammalian cells

    Depositor

    Bruno Feve, Jeremie Gautheron

    Article

    Gautheron et al Elife. 2021 Aug 3;10. pii: 68445. doi: 1

    Insert

    epoxide hydrolase 1 (EPHX1 Human)
    

    Tags

    flag

    Expression

    Mammalian

    Mutation

    c.337T>C

    Promoter

    CMV

    Available Since

    Oct. 7, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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16. pCMV6-Entry-EPHX1c.997A>C-Flag

    Plasmid

    #169171

    Purpose

    Expresses EPHX1 c.997A>C in mammalian cells

    Depositor

    Bruno Feve, Jeremie Gautheron

    Article

    Gautheron et al Elife. 2021 Aug 3;10. pii: 68445. doi: 1

    Insert

    epoxide hydrolase 1 (EPHX1 Human)
    

    Tags

    Flag

    Expression

    Mammalian

    Mutation

    c.997A>C

    Promoter

    CMV

    Available Since

    Oct. 7, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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17. pCMV6-Entry-EPHX1c.1212G>C-Flag

    Plasmid

    #169172

    Purpose

    Expresses EPHX1 c.1212G>C in mammalian cells

    Depositor

    Bruno Feve, Jeremie Gautheron

    Article

    Gautheron et al Elife. 2021 Aug 3;10. pii: 68445. doi: 1

    Insert

    epoxide hydrolase 1 (EPHX1 Human)
    

    Tags

    Flag

    Expression

    Mammalian

    Mutation

    c.1212G>C

    Promoter

    CMV

    Available Since

    Oct. 7, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. pCMV6-Entry-EPHX1c.1288G>C-Flag

    Plasmid

    #169173

    Purpose

    Expresses EPHX1 c.1288G>C in mammalian cells

    Depositor

    Bruno Feve, Jeremie Gautheron

    Article

    Gautheron et al Elife. 2021 Aug 3;10. pii: 68445. doi: 1

    Insert

    epoxide hydrolase 1 (EPHX1 Human)
    

    Tags

    Flag

    Expression

    Mammalian

    Mutation

    c.1288G>C

    Promoter

    CMV

    Available Since

    Oct. 7, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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19. ATX3 13Q- I77K Q78K W87K

    Plasmid

    #185908

    Purpose

    Expresses ataxin-3 full length with 3 UIMs and 13Q in the Poly-Q track-I77K, Q78K,W87K (N-terminal ) fused with His-Tag and TEV cleavage sequence (C-terminal).

    Depositor

    Sandra Macedo Ribeiro

    Article

    Figueiredo et al Cells. 2022 Jun 19;11(12). pii: cells111

    Insert

    ataxin-3 full length with 3 UIMs and 13Q in the Poly-Q track and point mutations I77K, Q78K and W87K (ATXN3 Human, Synthetic)
    

    Tags

    6x His-Tag and TEV cleavage site

    Expression

    Bacterial

    Mutation

    Point mutations in Atx3 gene I77K Q78K and W87K

    Available Since

    Aug. 25, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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20. pcDNA3.3-hAP1 1-419

    Plasmid

    #183644

    Purpose

    To (ectopically) express a mutant of ATP6AP1 lacking the interacting domain with PEN2; mammalian expression

    Depositor

    Sheng-cai Lin

    Article

    Ma et al Nature. 2022 Mar;603(7899):159-165. doi:

    Insert

    ATP6AP1 (ATP6AP1 Human)
    

    Tags

    myc

    Expression

    Mammalian

    Mutation

    truncated ATP6AP1 mutant; contains only amino aci…

    Promoter

    CMV

    Available Since

    June 1, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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