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Plasmid#188265PurposePlasmid ensures constitutive expression of the N-terminal fragment of split LYN kinase domain (aa 268-512), fused to the VPR activation domain, a flexible GS linker and the SV40 NLS signal at the C-terminusDepositorInsertnLYN267 (LYN Human)
UseTagsExpressionMammalianMutationPromoterAvailable sinceOct. 17, 2022AvailabilityAcademic Institutions and Nonprofits only -
pcDNA3-Lyn-RAB-EKARev
Plasmid#118477PurposeddRFP-based single-color ERK biosensor targeted to the plasma membrane.DepositorInsertLyn-RAB-EKARev
UseTagsN-terminal targeting sequence from Lyn-kinaseExpressionMammalianMutationPromoterCMVAvailable sinceMay 21, 2019AvailabilityAcademic Institutions and Nonprofits only -
pcDNA3-Lyn-Akt-STOPS
Plasmid#175009PurposePlasma membrane-targeted Akt-STOPS.DepositorInsertLyn-mCherry-Akt-STOPS
UseTagsN-terminal targeting sequence from Lyn kinase and…ExpressionMammalianMutationPromoterCMVAvailable sinceJan. 7, 2022AvailabilityAcademic Institutions and Nonprofits only -
dCas9-NLS-gs10-cLYN268
Plasmid#188259PurposePlasmid ensures constitutive expression of the C-terminal fragment of split LYN kinase domain (aa 239-267), fused to the catalytically inactive Cas9 (dCas9) protein, a flexible GS linker and the SV40 NLS signal at the N-terminusDepositorInsertcLYN268 (LYN Human)
UseCRISPRTagsExpressionMammalianMutationPromoterAvailable sinceOct. 18, 2022AvailabilityAcademic Institutions and Nonprofits only -
pCDNA3.0_LynLAMA-F98 IRES EGFP
Plasmid#130710PurposePlasmid encoding outer inner membrane localization of LAMA-F98 for GFP as a SNAP-Tag-fusion and EGFPDepositorInsertLyn11-SNAP-Tag-LAMA-F98 IRES EGFP
UseTagsLyn11 and SNAP-TagExpressionMammalianMutationPromoterAvailable sinceAug. 26, 2019AvailabilityAcademic Institutions and Nonprofits only -
pCAG-loxpSTOPloxp-lyn-NeonGreen
Plasmid#175257Purposemembrane target protein labellingDepositorInsertLyn membrane targeting motif
UseCre/LoxTagsmNeonGreenExpressionMammalianMutationNone (wt)PromoterpCAGAvailable sinceOct. 5, 2022AvailabilityAcademic Institutions and Nonprofits only -
pcDNA3-Lyn-sACt-mCherry
Plasmid#138216PurposeEncodes residues 1-469 of rat soluble adenylyl cyclase (ADCY10) fused to mCherry; plasma membrane targeted.DepositorInsertLyn-sACt-mCherry (Adcy10 Rat)
UseTagsN-terminal targeting sequence from Lyn kinase and…ExpressionMammalianMutationPromoterCMVAvailable sinceMarch 24, 2021AvailabilityAcademic Institutions and Nonprofits only -
tol2-mpx-lyn-GFP
Plasmid#35037DepositorInsertLyn-GFP (lyn Zebrafish)
UseZebrafish expressionTagsGFPExpressionMammalianMutationPromoterAvailable sinceMarch 5, 2012AvailabilityAcademic Institutions and Nonprofits only -
Lyn-iTrkA-mCh-CRY2
Plasmid#106169Purposemammalian expression of Lyn-tagged intracellular domain of TrkA (aa 450-799) fused to mCherry and CRY2PHR (aa 1-498)DepositorInsertLyn iTrkA mCherry CRY2PHR (CRY2 Rat, Mustard Weed)
UseTagsExpressionMammalianMutationPromoterCMVAvailable sinceAug. 3, 2018AvailabilityAcademic Institutions and Nonprofits only -
pLIC-lyn11-myc-LOV2GIVe (FA)
Plasmid#170626PurposeFor the mammalian expression of mLOV2GIVe GEF-deficient mutation F1685ADepositorInsertLyn11-myc-LOV2GIVe (FA)
UseTagsmycExpressionMammalianMutationPromoterCMVAvailable sinceJune 29, 2021AvailabilityAcademic Institutions and Nonprofits only -
pEGFP-N1-zebrafish lyn–GFP
Plasmid#35956DepositorInserthumanized zebrafish lyn (lyn Zebrafish)
UseTagsEGFPExpressionMammalianMutationwtPromotercmvAvailable sinceApril 18, 2012AvailabilityAcademic Institutions and Nonprofits only -
pTagBFP2-C1-lynN11-FKBP-PI-PLCN187
Plasmid#139308PurposeN-terminal half of split PI-PLC targeted to plasma membraneDepositorInsertLYN(1-11):RSANS[GA]4:TagBFP2: FKBP1A(3-108): [GGSA]4GG:L. monocytogenes PI-PLC(1-187)
UseTagsExpressionMammalianMutationPromoterAvailable sinceApril 6, 2020AvailabilityAcademic Institutions and Nonprofits only -
pcDNA5/FRT/TO_Lyn11-STf
Plasmid#182008PurposeCMV overexpression of SNAP-tag fast at the inner leaflet of the plasma membrane of mammalian cell linesDepositorInsertLyn11-STf
UseTagsExpressionMammalianMutationFast mutation on SNAP-tag E30RPromoterCMVAvailable sinceNov. 10, 2022AvailabilityAcademic Institutions and Nonprofits only -
pSBbi-Pur-Lyn-AktAR2-EV
Plasmid#125199PurposeSB-transposon plasmid for stable expression of lipid raft-targeted Lyn-AktAR2-EV variant of FRET-based AKT activity reporterDepositorInsertLyn-AktAR2-EV
UseTransposonTagsEV linker, cpVenus[E172] and Lyn tag (GCIKSKRKD),…ExpressionMammalianMutationPromoterEF1a/RPBSAAvailable sinceMay 13, 2019AvailabilityAcademic Institutions and Nonprofits only -
AAV-hSyn-Lyn-Y-GECO1
Plasmid#58200PurposeExpress the membrane targeted Y-GECO1 in neuronsDepositorInsertY-GECO1.0
UseAAVTagsExpressionMutationPromoterhSynAvailable sinceJuly 22, 2014AvailabilityAcademic Institutions and Nonprofits only -
Lyn-CFP-GAI(1-172)
Plasmid#37313DepositorInsertGAI (GAI Mustard Weed)
UseTagsCFP and LynExpressionMammalianMutationcontains aa 1-172PromoterCMVAvailable sinceJune 15, 2012AvailabilityAcademic Institutions and Nonprofits only -
Lyn-CFP-GAI(1-532)
Plasmid#37314DepositorInsertGAI (GAI Mustard Weed)
UseTagsCFP and LynExpressionMammalianMutationcontains aa 1-532PromoterCMVAvailable sinceJune 15, 2012AvailabilityAcademic Institutions and Nonprofits only -
Lyn-CFP-GAI(1-151)
Plasmid#37312DepositorInsertGAI (GAI Mustard Weed)
UseTagsCFP and LynExpressionMammalianMutationcontains aa 1-151PromoterCMVAvailable sinceJune 15, 2012AvailabilityAcademic Institutions and Nonprofits only -
pCDNA3-lyn10-mCherry-dLOVPLD
Plasmid#219556PurposePM-targeted catalytically dead LOVPLDDepositorInsertlyn10-mCherry-dLOVPLD
UseTagsmCherryExpressionMammalianMutationH170A mutation on PLDPromoterAvailable sinceMay 17, 2024AvailabilityAcademic Institutions and Nonprofits only -
pLIC-lyn11-myc-LOV2GIVe (L) (FA)
Plasmid#170627PurposeFor the mammalian expression of mLOV2GIVe lit-mimicking mutation I539E and the GEF-deficient mutation F1685ADepositorInsertLyn11-myc-LOV2GIVe (L) (FA)
UseTagsmycExpressionMammalianMutationPromoterCMVAvailable sinceJuly 20, 2021AvailabilityAcademic Institutions and Nonprofits only