We narrowed to 34,080 results for: MUT

1. pCMV-RosaR4 KKR mutations

   Plasmid

   #37199

   Depositor

   Charles Gersbach

   Article

   Perez-Pinera et al Nucleic Acids Res. 2012 Apr 1;40(8):3741

   Insert

   FokI (fused to RosaR4 ZFN)
   

   Use

   Zfn expression

   Tags

   HA, ROSA26 eZFNs R4, and SV40 NLS

   Expression

   Mammalian

   Mutation

   I538K, E490K, and H537R

   Promoter

   CMV

   Available Since

   July 19, 2012

   Availability

   Academic Institutions and Nonprofits only

   

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2. pAAV-hsyn-GRAB_DA-mut

   Plasmid

   #140555

   Purpose

   Expresses the DA-insensitive control sensor GRAB_DA-mut in neurons

   Depositor

   Yulong Li

   Article

   Sun et al Nat Methods. 2020 Nov;17(11):1156-1166.

   Has Service

   AAV9

   Insert

   DA-insensitive sensor GRAB_DA-mut (control sensor)
   

   Use

   AAV

   Promoter

   hSyn

   Available Since

   July 29, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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3. pCI-neo-RL-ZEB1 200bmutx5

   Plasmid

   #35537

   Depositor

   Greg Goodall

   Article

   Gregory et al Nat Cell Biol. 2008 May;10(5):593-601. E

   Insert

   3'UTR of ZEB1 (ZEB1 Budding Yeast, Human)
   

   Use

   Luciferase

   Expression

   Mammalian

   Mutation

   5 mutations in miR200b seed regions of 3'UTR…

   Available Since

   May 10, 2012

   Availability

   Academic Institutions and Nonprofits only

   

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4. pcDNA3-FLAG-mTET2 CD mutant

   Plasmid

   #89896

   Purpose

   Expresses mouse TET2 CD mutant in mammalian cells

   Depositor

   Yue Xiong

   Article

   Nakagawa et al Mol Cell. 2015 Jan 22;57(2):247-60. doi:

   Insert

   TET2 (Tet2 Mouse)
   

   Tags

   Flag

   Expression

   Mammalian

   Mutation

   CD (cysteine-rich, dioxygenase domain) truncation…

   Available Since

   May 3, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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5. pCI-neo-RL-ZEB2 200bmut

   Plasmid

   #35538

   Depositor

   Greg Goodall

   Article

   Gregory et al Nat Cell Biol. 2008 May;10(5):593-601. E

   Insert

   3'UTR of ZEB2 gene (ZEB2 Human)
   

   Use

   Luciferase

   Expression

   Mammalian

   Mutation

   6 Mutations in the miR-200b seed regions of the Z…

   Available Since

   June 25, 2012

   Availability

   Academic Institutions and Nonprofits only

   

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6. pALOD4 non-binding mutant

   Plasmid

   #111027

   Purpose

   Expresses non-binding mutant version of p-ALOD4, has six inactivating mutations (G501A, T502A, T503A, L504A, Y505A, and P506A)

   Depositor

   Arun Radhakrishnan

   Article

   Gay et al Biophys J. 2015 Mar 24;108(6):1459-69. d

   Insert

   Domain 4 of Anthrolysin O
   

   Tags

   His6 tag

   Expression

   Bacterial

   Mutation

   Mutations: S404C, C472A, G501A, T502A, T503A, L5…

   Promoter

   T7

   Available Since

   June 27, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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7. pcDNA3.1-mCherry-CyrCR1.mutant

   Plasmid

   #128746

   Purpose

   Expresses mCherry in mammalian cells. ~200 nt of Cyrano with 5 point mutations in miR-7 site inserted in mCherry 3'UTR.

   Depositor

   David Bartel

   Article

   Kleaveland et al Cell. 2018 Jul 12;174(2):350-362.e17. do

   Insert

   Cyrano conserved region (CR1) with mutant miR-7 site (OIP5-AS1 Human)
   

   Expression

   Mammalian

   Mutation

   5 point mutations disrupting the miR-7 site

   Promoter

   CMV

   Available Since

   Aug. 14, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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8. K9L mutant of H3K9me3 biosensor

   Plasmid

   #120807

   Purpose

   FRET biosensor. Eliminating the H3 lysine 9 methylation site in H3K9me3 biosensor to abolish the detection capability

   Depositor

   Yingxiao Wang

   Article

   Peng et al Proc Natl Acad Sci U S A. 2018 Nov 26. p

   Insert

   Truncated YPet-HP1-EV linker-ECFP-mouse histone H3(K9L mutation)
   

   Expression

   Mammalian

   Mutation

   lysine 9 is mutated to leucine 9 on histone H3

   Promoter

   CMV

   Available Since

   Feb. 11, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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9. pCMV-RosaL6 ELD mutations

   Plasmid

   #37198

   Depositor

   Charles Gersbach

   Article

   Perez-Pinera et al Nucleic Acids Res. 2012 Apr 1;40(8):3741

   Insert

   FokI (fused to Rosa L6 ZFN)
   

   Use

   Zfn expression

   Tags

   HA, ROSA26 eZFNs L6, and SV40 NLS

   Expression

   Mammalian

   Mutation

   Q486E, I499L and N496D

   Promoter

   CMV

   Available Since

   July 19, 2012

   Availability

   Academic Institutions and Nonprofits only

   

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10. pBbdCas9S(RBSmut)_Psyn-sgRNA500

    Plasmid

    #149576

    Purpose

    parental, all-in-one CRISPRi vector for B. burgdorferi, parental for gRNA cloning

    Depositor

    Christine Jacobs-Wagner

    Article

    Takacs et al Appl Environ Microbiol. 2020 Nov 30. pii

    Type

    Empty backbone

    Use

    CRISPR

    Expression

    Bacterial

    Promoter

    PflaB, PpQE30, Psyn

    Available Since

    Nov. 25, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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11. hRIP3 GFP RHIM mut

    Plasmid

    #41385

    Depositor

    Francis Chan

    Article

    Cho et al Cell. 2009 Jun 12;137(6):1112-23.

    Insert

    RIP3 (RIPK3 Human)
    

    Tags

    GFP

    Expression

    Mammalian

    Mutation

    RHIM mutant (AAAA-459-462)

    Promoter

    CMV

    Available Since

    Dec. 4, 2012

    Availability

    Academic Institutions and Nonprofits only

12. pRK5-mEGFP-PHOX2B-MUT

    Plasmid

    #194577

    Purpose

    Mammalian Expression of mEGFP-PHOX2B Mutant (S207Afs*102) Fusion Protein

    Depositor

    Denes Hnisz

    Article

    Mensah et al Nature. 2023 Feb;614(7948):564-571. doi:

    Insert

    PHOX2B (PHOX2B Human)
    

    Tags

    mEGFP

    Expression

    Mammalian

    Mutation

    S207Afs*102

    Available Since

    Feb. 22, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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13. pAG223 PRKD1 3'UTR mut

    Plasmid

    #12042

    Depositor

    David Bartel

    Article

    Farh et al Science. 2005 Dec 16. 310(5755):1817-21.

    Insert

    PRKD1 3'UTR mut (PRKD1 Human)
    

    Use

    Luciferase

    Expression

    Mammalian

    Mutation

    Mutations in microRNA recognition sites (seed mat…

    Available Since

    June 8, 2006

    Availability

    Academic Institutions and Nonprofits only

14. pAG225 HIPK1 3'UTR mut

    Plasmid

    #12044

    Depositor

    David Bartel

    Article

    Farh et al Science. 2005 Dec 16. 310(5755):1817-21.

    Insert

    HIPK1 3'UTR mut (HIPK1 Human)
    

    Use

    Luciferase

    Expression

    Mammalian

    Mutation

    Mutations in microRNA recognition sites (seed mat…

    Available Since

    June 8, 2006

    Availability

    Academic Institutions and Nonprofits only

15. pAG177 HIPK1 3'UTR mut

    Plasmid

    #12035

    Depositor

    David Bartel

    Article

    Farh et al Science. 2005 Dec 16. 310(5755):1817-21.

    Insert

    N10 3'UTR mut (HIPK1 Human)
    

    Use

    Luciferase

    Expression

    Mammalian

    Mutation

    Mutations in microRNA recognition sites (seed mat…

    Available Since

    June 8, 2006

    Availability

    Academic Institutions and Nonprofits only

    

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16. pGL3-OF (mutant TCF-4 sites)

    Plasmid

    #16559

    Depositor

    Bert Vogelstein

    Article

    Shih et al Cancer Res. 2000 Mar 15. 60(6):1671-6.

    Insert

    TCF-4 binding sites (TCF4 Human)
    

    Use

    Luciferase

    Tags

    Luciferase

    Expression

    Mammalian

    Mutation

    3 copies of mutant Tcf-4 binding sites

    Available Since

    March 28, 2008

    Availability

    Academic Institutions and Nonprofits only

    

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17. pcDNA3.1_3xFlagEzh2 RNA binding mutant

    Plasmid

    #173718

    Purpose

    RNA-binding mutant EZH2 expression plasmid with 3XFLAG tag

    Depositor

    Thomas Cech

    Article

    Long et al Nat Genet. 2020 Sep;52(9):931-938. doi:

    Insert

    EZH2 RNA-binding mutant
    

    Tags

    3XFLAG

    Expression

    Mammalian

    Available Since

    Aug. 26, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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18. pICE-HA-Ku70-siR-Mut6E

    Plasmid

    #82330

    Purpose

    Plasmid for constitutive or doxy-inducible expression of mutant human Ku70 unable to bind DNA and resistant to siRNA. Confers resistance to puro. Use T-REx cells for doxycycline-inducible expression.

    Depositor

    Patrick Calsou, Sébastien Britton

    Article

    Lamaa et al EMBO Rep. 2016 Apr;17(4):508-18. doi: 10

    Insert

    Ku70 (XRCC6 Human)
    

    Tags

    HA

    Expression

    Mammalian

    Mutation

    Mut6E corresponding to K282E K287E T300E K331E K3…

    Promoter

    CMV-tet

    Available Since

    Sept. 13, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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19. pAAV-hSyn-DIO-GRAB_eCB2.0mut

    Plasmid

    #164607

    Purpose

    Express the endocannabinoid non-responsive sensor GRAB_eCB2.0 in Cre positive neurons

    Depositor

    Yulong Li

    Article

    Dong et al Nat Biotechnol. 2021 Nov 11. pii: 10.103

    Insert

    Endocannabinoid non-responsive sensor GRAB_eCBmut
    

    Use

    AAV

    Mutation

    S383T, F177A

    Promoter

    hSyn

    Available Since

    Feb. 23, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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20. pRK5-mEGFP-HMGB3-MUT

    Plasmid

    #194565

    Purpose

    Mammalian Expression of mEGFP-HMGB3 Mutant (K161Ifs*55) Fusion Protein

    Depositor

    Denes Hnisz

    Article

    Mensah et al Nature. 2023 Feb;614(7948):564-571. doi:

    Insert

    HMGB3 (HMGB3 Human)
    

    Tags

    mEGFP

    Expression

    Mammalian

    Mutation

    K161Ifs*55

    Available Since

    Feb. 22, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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