We narrowed to 2,518 results for: neurod

1. pTWIN1-His6-Ssp-Htt2-90(A2C)-49Q

   Plasmid

   #114627

   Purpose

   Bacterial expression of Htt fragment containing amino acids 2-90, with A2C cysteine mutation and a 49 polyQ repeat

   Depositor

   Hilal Lashuel

   Article

   Warner JB et al J Am Chem Soc. 2017 Oct 18;139(41):14456

   Insert

   Huntingtin Exon1 fragment (HTT Human)
   

   Use

   Tags

   His6-Ssp DnaB intein

   Expression

   Bacterial

   Mutation

   A2C; 49 polyQ repeat

   Promoter

   Available since

   Sept. 19, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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2. pTWIN1-His6-Ssp-Htt2-90-49Q-P90C

   Plasmid

   #114631

   Purpose

   Bacterial expression of Htt fragment containing amino acids 2-90, with P90C cysteine mutation and a 49 polyQ repeat

   Depositor

   Hilal Lashuel

   Article

   Warner JB et al J Am Chem Soc. 2017 Oct 18;139(41):14456

   Insert

   Huntingtin Exon1 fragment (HTT Human)
   

   Use

   Tags

   His6-Ssp DnaB intein

   Expression

   Bacterial

   Mutation

   P90C; 49 polyQ repeat

   Promoter

   Available since

   Sept. 18, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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3. GAK gRNA (BRDN0001146687)

   Plasmid

   #76470

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human GAK

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   GAK (GAK Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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4. EF1a-FXN-P2A-mRuby2(miRE.FF4)-TS.FF6x1-bGH

   Plasmid

   #235301

   Purpose

   ComMAND open-loop circuit regulating FXN-P2A-mRuby2 (therapeutically relevant gene)

   Depositor

   Kate Galloway

   Article

   Love et al Cell Syst. 2025 Apr 22:101269. doi: 10.1

   Insert

   FXN-P2A-mRuby2 (FXN Human)
   

   Use

   Synthetic Biology

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   EF1a (human EF1a)

   Available since

   June 11, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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5. EF1a-FXN-P2A-mRuby2-bGH

   Plasmid

   #235300

   Purpose

   ComMAND base gene regulating FXN-P2A-mRuby2 (therapeutically relevant gene)

   Depositor

   Kate Galloway

   Article

   Love et al Cell Syst. 2025 Apr 22:101269. doi: 10.1

   Insert

   FXN-P2A-mRuby2 (FXN Human)
   

   Use

   Synthetic Biology

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   EF1a (human EF1a)

   Available since

   May 30, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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6. EF1a-FXN-P2A-mRuby2(miRE.FF4)-TS.FF4x1-bGH

   Plasmid

   #235302

   Purpose

   ComMAND closed-loop circuit regulating FXN-P2A-mRuby2 (therapeutically relevant gene)

   Depositor

   Kate Galloway

   Article

   Love et al Cell Syst. 2025 Apr 22:101269. doi: 10.1

   Insert

   FXN-P2A-mRuby2 (FXN Human)
   

   Use

   Synthetic Biology

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   EF1a (human EF1a)

   Available since

   May 30, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

7. pUC19_msfGFP-FUS-repair-tempate

   Plasmid

   #237684

   Purpose

   For knock-in msfGFP to FUS locus

   Depositor

   Denes Hnisz

   Article

   Zhang et al Nature. 2025 Jun 4. doi: 10.1038/s41586-

   Insert

   FUS (FUS Human)
   

   Use

   CRISPR

   Tags

   msfGFP

   Expression

   Mutation

   Promoter

   Available since

   May 6, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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8. A1-LCD allW D262V

   Plasmid

   #234616

   Purpose

   Bacterial expression of N-terminally 6His tagged hnRNPA1 LCD (186-320) D262V with all aromatic amino acids mutated to W keeping the hexapeptide fibril core (SYNDFG) intact.

   Depositor

   Tanja Mittag

   Article

   Das et al bioRxiv [Preprint]. 2024 Mar 3:2024.02.2

   Insert

   hnRNPA1_LCD_allW D262V (HNRNPA1 Human)
   

   Use

   Tags

   6xHis-TEV

   Expression

   Bacterial

   Mutation

   C-terminal domain (186-320) bearing familial ALS …

   Promoter

   T7

   Available since

   April 15, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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9. A1-LCD allW D262N

   Plasmid

   #234615

   Purpose

   Bacterial expression of N-terminally 6His tagged hnRNPA1 LCD (186-320) D262N with all aromatic amino acids mutated to W keeping the hexapeptide fibril core (SYNDFG) intact.

   Depositor

   Tanja Mittag

   Article

   Das et al bioRxiv [Preprint]. 2024 Mar 3:2024.02.2

   Insert

   hnRNPA1_LCD_allW D262N (HNRNPA1 Human)
   

   Use

   Tags

   6xHis-TEV

   Expression

   Bacterial

   Mutation

   C-terminal domain (186-320) bearing familial ALS …

   Promoter

   T7

   Available since

   April 15, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. pPB-EF1A-HALO-hLRRK2 (LIR1+2 mutant WEVL -> AEVA / WTFI -> ATFA)

    Plasmid

    #229744

    Purpose

    Expresses Halo tagged human LRRK2 with LIR1 and LIR2 point mutations in mammalian cells. Stable expression with piggybac transposase.

    Depositor

    Shawn Ferguson

    Article

    Bentley-DeSousa et al J Cell Biol. 2025 Feb 3;224(2):e20231015

    Insert

    LRRK2 (LRRK2 Human)
    

    Use

    Tags

    Halo

    Expression

    Mammalian

    Mutation

    LIR1+2 mutant WEVL -> AEVA / WTFI -> ATFA

    Promoter

    EF1A

    Available since

    Feb. 24, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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11. pRP.ATM c.7865C>T

    Plasmid

    #226554

    Purpose

    Minigene encoding the ATM c.7865C>T mutation

    Depositor

    Dave Wee

    Article

    Tabaglio et al Mol Ther Nucleic Acids. 2025 Jan 7;36(1)

    Insert

    ATM (ATM Human)
    

    Use

    Tags

    3xFLAG

    Expression

    Mammalian

    Mutation

    c.7865C>T

    Promoter

    Available since

    Jan. 13, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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12. pAAV hGRN4

    Plasmid

    #213684

    Purpose

    Expresses human granulin-4 with an N-terminal twin-Strep-FLAG tag

    Depositor

    Thomas Kukar

    Article

    Root et al Cell Rep. 2024 Nov 19;43(12):114985. doi

    Insert

    Human granulin-4 (hGRN4) (GRN Human)
    

    Use

    AAV

    Tags

    Twin-Strep tag and FLAG tag (after signal peptide…

    Expression

    Mutation

    Promoter

    cytomegalovirus enhancer/chicken β-actin promoter

    Available since

    Dec. 10, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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13. pcDNA3.1(-).TagRFP.T-2A-V5-8D2Q.Tau2N4R-WPRE

    Plasmid

    #226382

    Purpose

    Expresses tau propagation ORF with V5 tag on 8D2Q mutant 2N4R tau

    Depositor

    Bradley Hyman

    Article

    Dickson et al J Neuropathol Exp Neurol. 2025 Jun 1;84(

    Insert

    Tau2N4R (MAPT Human, synthetic)
    

    Use

    Tags

    TagRFP.T.2A.V5

    Expression

    Mammalian

    Mutation

    8D2Q.Tau2N4R

    Promoter

    Available since

    Nov. 14, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. pcDNA3.1(-).TagRFP.T-2A-V5-20D3Q.Tau2N4R-WPRE

    Plasmid

    #226383

    Purpose

    Expresses tau propagation ORF with V5 tag on 20D3Q mutant 2N4R tau

    Depositor

    Bradley Hyman

    Article

    Dickson et al J Neuropathol Exp Neurol. 2025 Jun 1;84(

    Insert

    Tau2N4R (MAPT Human, synthetic)
    

    Use

    Tags

    TagRFP.T.2A.V5

    Expression

    Mammalian

    Mutation

    20D3Q, Tau2N4R

    Promoter

    Available since

    Nov. 14, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. pcDNA3.1(-).TagRFP.T-2A-V5-8A2R.Tau2N4R-WPRE

    Plasmid

    #226384

    Purpose

    Expresses tau propagation ORF with V5 tag on 8A2R mutant 2N4R tau

    Depositor

    Bradley Hyman

    Article

    Dickson et al J Neuropathol Exp Neurol. 2025 Jun 1;84(

    Insert

    Tau2N4R (MAPT Human, synthetic)
    

    Use

    Tags

    TagRFP.T.2A.V5

    Expression

    Mammalian

    Mutation

    8A2R, Tau2N4R

    Promoter

    Available since

    Nov. 14, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. pcDNA3.1(-).TagRFP.T-2A-V5-20A3R.Tau2N4R-WPRE

    Plasmid

    #226385

    Purpose

    Expresses tau propagation ORF with V5 tag on 20A3R mutant 2N4R tau

    Depositor

    Bradley Hyman

    Article

    Dickson et al J Neuropathol Exp Neurol. 2025 Jun 1;84(

    Insert

    Tau2N4R (MAPT Human, synthetic)
    

    Use

    Tags

    TagRFP.T.2A.V5

    Expression

    Mammalian

    Mutation

    20A3R, Tau2N4R

    Promoter

    Available since

    Nov. 14, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. pcDNA3.1(-).TagRFP.T-2A-V5-K281Q.Tau2N4R-WPRE

    Plasmid

    #226386

    Purpose

    Expresses tau propagation ORF with V5 tag on K281Q mutant 2N4R tau

    Depositor

    Bradley Hyman

    Article

    Dickson et al J Neuropathol Exp Neurol. 2025 Jun 1;84(

    Insert

    Tau2N4R (MAPT Human, synthetic)
    

    Use

    Tags

    TagRFP.T.2A.V5

    Expression

    Mammalian

    Mutation

    K281Q, 2N4R

    Promoter

    Available since

    Nov. 14, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. pcDNA3.1(-).TagRFP.T-2A-V5-K353Q.Tau2N4R-WPRE

    Plasmid

    #226387

    Purpose

    Expresses tau propagation ORF with V5 tag on K353Q mutant 2N4R tau

    Depositor

    Bradley Hyman

    Article

    Dickson et al J Neuropathol Exp Neurol. 2025 Jun 1;84(

    Insert

    Tau2N4R (MAPT Human, synthetic)
    

    Use

    Tags

    TagRFP.T.2A.V5

    Expression

    Mammalian

    Mutation

    K353Q, 2N4R

    Promoter

    Available since

    Nov. 14, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. pcDNA3.1(-).TagRFP.T-2A-V5-S198D.Tau2N4R-WPRE

    Plasmid

    #226388

    Purpose

    Expresses tau propagation ORF with V5 tag on S189D mutant 2N4R tau

    Depositor

    Bradley Hyman

    Article

    Dickson et al J Neuropathol Exp Neurol. 2025 Jun 1;84(

    Insert

    Tau2N4R (MAPT Human, synthetic)
    

    Use

    Tags

    TagRFP.T.2A.V5

    Expression

    Mammalian

    Mutation

    S198D.Tau2N4R

    Promoter

    Available since

    Nov. 14, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. pcDNA3.1(-).TagRFP.T-2A-V5-S199D.Tau2N4R-WPRE

    Plasmid

    #226389

    Purpose

    Expresses tau propagation ORF with V5 tag on S199D mutant 2N4R tau

    Depositor

    Bradley Hyman

    Article

    Dickson et al J Neuropathol Exp Neurol. 2025 Jun 1;84(

    Insert

    Tau2N4R (MAPT Human, synthetic)
    

    Use

    Tags

    TagRFP.T-2A-V5

    Expression

    Mammalian

    Mutation

    S199D, Tau2N4R

    Promoter

    Available since

    Nov. 14, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge