We narrowed to 4,848 results for: pAAV

1. pAAV-MYL2-TadA8e-Sauri-U6-Camk2d sgRNA7

   Plasmid

   #220124

   Purpose

   Expresses SauriABE8e by MYL2 promoter and sgRNA targeting murine Camk2d intron7 5' splice site by U6 promoter

   Depositor

   Yuxuan Guo

   Article

   Liu et al Circ Res. 2025 Jan 16. doi: 10.1161/CIRC

   Insert

   MYL2, TadA, nSauriCas9
   

   Use

   AAV

   Tags

   Expression

   Mutation

   Promoter

   MYL2

   Available since

   Jan. 16, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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2. pAAV-MYL2-HA-TadA8e-Sauri-U6-Camk2d sgRNA7

   Plasmid

   #220127

   Purpose

   Expresses SauriABE8e by MYL2 promoter and sgRNA targeting murine Camk2d intron7 5' splice site by U6 promoter, and add an HA tag fused to TadA

   Depositor

   Yuxuan Guo

   Article

   Liu et al Circ Res. 2025 Jan 16. doi: 10.1161/CIRC

   Insert

   MYL2, TadA, nSauriCas9
   

   Use

   AAV

   Tags

   HA tag

   Expression

   Mutation

   Promoter

   MYL2

   Available since

   Jan. 16, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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3. pAAV-EFS-TadA8e-Nme2-U6-sgRNA scaffold

   Plasmid

   #226933

   Purpose

   Encoding Nme2ABE8e and sgRNA cassette on a single AAV

   Depositor

   Yuxuan Guo

   Article

   Liu et al Circ Res. 2025 Jan 16. doi: 10.1161/CIRC

   Insert

   TadA8e, nNme2Cas9
   

   Use

   AAV

   Tags

   Expression

   Mutation

   Promoter

   EFS

   Available since

   Jan. 16, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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4. pAAV-EFS-TadA8e-SaKKH-U6-sgRNA scaffold

   Plasmid

   #226935

   Purpose

   Encoding SaKKHABE8e and sgRNA cassette on a single AAV

   Depositor

   Yuxuan Guo

   Article

   Liu et al Circ Res. 2025 Jan 16. doi: 10.1161/CIRC

   Insert

   TadA8e, nSaKKHCas9
   

   Use

   AAV

   Tags

   Expression

   Mutation

   Promoter

   EFS

   Available since

   Jan. 16, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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5. pC131: pAAV.CMV-CasRx-VEGFA sgRNA array

   Plasmid

   #203444

   Purpose

   Plasmid expressing active RfxCas13d with an array of three VEGFA mRNA targeting gRNAs

   Depositor

   Guei-Sheung Liu

   Article

   Kumar et al Proc Natl Acad Sci U S A. 2024 Nov 5;121

   Inserts

   U6-VEGFA sgRNA array
   RfxCas13d
   

   Use

   AAV

   Tags

   HA and NLS

   Expression

   Mammalian

   Mutation

   Promoter

   CMV and U6

   Available since

   Dec. 12, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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6. pM150: pAAV.CMV-Cas13e-VEGFA sgRNA array

   Plasmid

   #203448

   Purpose

   Plasmid expressing active Cas13e with an array of three VEGFA mRNA targeting gRNAs

   Depositor

   Guei-Sheung Liu

   Article

   Kumar et al Proc Natl Acad Sci U S A. 2024 Nov 5;121

   Inserts

   U6-VEGFA sgRNA array
   Cas13e
   

   Use

   AAV

   Tags

   HA and NLS

   Expression

   Mammalian

   Mutation

   Promoter

   CMV and U6

   Available since

   Dec. 12, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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7. pM156: pAAV.CMV-Cas13e (GenScript CO)-VEGFA sgRNA

   Plasmid

   #203452

   Purpose

   Plasmid expressing active and codon optimised Cas13e with VEGFA gRNA

   Depositor

   Guei-Sheung Liu

   Article

   Kumar et al Proc Natl Acad Sci U S A. 2024 Nov 5;121

   Inserts

   U6-VEGFA sgRNA
   Cas13e
   

   Use

   AAV

   Tags

   HA and NLS

   Expression

   Mammalian

   Mutation

   Promoter

   CMV and U6

   Available since

   Dec. 12, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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8. pAAV-U6-sgRev-erba-hSyn-mCherry-KASH

   Plasmid

   #223226

   Purpose

   guideRNA targeting the mouse Rev-erb alpha (Nr1d1)

   Depositor

   Kyungjin Kim

   Article

   Park et al Commun Biol. 2024 Aug 15;7(1):998. doi:

   Insert

   Nr1d1 (Nr1d1 Mouse)
   

   Use

   AAV, CRISPR, and Mouse Targeting

   Tags

   mCherry

   Expression

   Mammalian

   Mutation

   Promoter

   U6

   Available since

   Sept. 11, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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9. AiP1921 - pAAV-AiE2447m-SYFP2-WPRE-BGHpA

   Plasmid

   #214581

   Purpose

   AiE2447m is an enhancer sequence, designed to drive AAV-mediated transgene expression in specific populations of brain cells

   Depositor

   The Allen Institute for Brain Science, Bosiljka Tasic

   Article

   Ben-Simon et al Cell. 2025 May 16:S0092-8674(25)00513-6.

   Insert

   SYFP2
   

   Use

   AAV

   Tags

   Expression

   Mutation

   Promoter

   minBG

   Available since

   June 24, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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10. pAAV-hSyn-DIO-NES-jRGECO1a-WPRE

    Plasmid

    #216276

    Purpose

    AAV vector with hSynapsin promoter and DIO Lox sites for Cre-On expression of red fluorescent calcium indicator jRGECO1a

    Depositor

    Guohong Cui

    Article

    Meng et al Neuron. 2018 May 16;98(4):707-717.e4. do

    Insert

    NES-jRGECO1a
    

    Use

    AAV and Cre/Lox

    Tags

    6XHIS and Xpress

    Expression

    Mutation

    Promoter

    human synapsin 1 (hSyn)

    Available since

    May 28, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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11. pAAV-CMVd1-NLS-GAL4-iLight-VP16

    Plasmid

    #219549

    Purpose

    NLS-Gal4(1-65)-iLight-VP16 construc expression in mammalian cells. pAAV vector.

    Depositor

    Vladislav Verkhusha

    Article

    Baloban et al Protein Sci. 2024 May;33(5):e4993. doi:

    Insert

    NLS-Gal4(1-65)-iLight-VP16
    

    Use

    AAV

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    CMVd1

    Available since

    May 23, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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12. pAAV-hSyn-frt-DIO-hM3D(Gq)-mCherry

    Plasmid

    #217397

    Purpose

    Expresses the hM3D(Gq) excitatory DREADD fused to mCherry, in a Cre-ON and FLP-OFF dependent manner, under the control of hSyn promoter

    Depositor

    Oscar Marin

    Insert

    hM3D(Gq)-mCherry
    

    Use

    AAV

    Tags

    mCherry

    Expression

    Mammalian

    Mutation

    Promoter

    human Synapsin 1

    Available since

    May 11, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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13. pAAV-hSyn-frt-DIO-hM4D(Gi)-mCherry

    Plasmid

    #217398

    Purpose

    Expresses the hM4D(Gi) inhibitory DREADD fused to mCherry, in a Cre-ON and FLP-OFF dependent manner, under the control of hSyn promoter

    Depositor

    Oscar Marin

    Insert

    hM4D(Gi)-mCherry
    

    Use

    AAV

    Tags

    mCherry

    Expression

    Mammalian

    Mutation

    Promoter

    human Synapsin 1

    Available since

    May 11, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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14. pAAV-Syn1-DIO-Snca (human A53T)

    Plasmid

    #214201

    Purpose

    For Cre-dependent expression of alpha synuclein (human gene containing A53T mutation)

    Depositor

    Thomas Hnasko

    Article

    Steinkellner et al Brain. 2022 Apr 29;145(3):879-886. doi:

    Insert

    Snca (A53T) (SNCA Human)
    

    Use

    AAV and Cre/Lox

    Tags

    Expression

    Mammalian

    Mutation

    A53T

    Promoter

    Available since

    March 29, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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15. pOTTC1992 - pAAV EF1a CoV2 Orf3a-2xStrep

    Plasmid

    #213542

    Purpose

    AAV viral vector packaging plasmid that expresses CoV2

    Depositor

    Brandon Harvey, Christopher Richie

    Insert

    CoV2 Orf3a-2xStrep (ORF3a Human, Severe acute respiratory syndrome coronavirus 2)
    

    Use

    AAV

    Tags

    Expression

    Mutation

    Promoter

    EF1a

    Available since

    Feb. 26, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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16. pOTTC1993 - pAAV EF1a CoV2 protE-2xStrep

    Plasmid

    #213543

    Purpose

    AAV viral vector packaging plasmid that expresses CoV2

    Depositor

    Brandon Harvey, Christopher Richie

    Insert

    CoV2 protE-2xStrep (E Human, Severe acute respiratory syndrome coronavirus 2)
    

    Use

    AAV

    Tags

    Expression

    Mutation

    Promoter

    EF1a

    Available since

    Feb. 26, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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17. pAAV-hSyn-DIO-myr-rsEGFP2- LDLR

    Plasmid

    #213399

    Purpose

    double floxed, myristoylation site (myr) and LDLR, fused to reversibly switchable EGFP rsEGFP2

    Depositor

    Katrin Willig

    Article

    Willig et al Cell Rep. 2021 Jun 1;35(9):109192. doi:

    Insert

    rsEGFP2
    

    Use

    AAV

    Tags

    C-terminal (Ct) cytoplasmic domains of low densit…

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Feb. 21, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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18. pAAV-EFS-TadA8e-Sauri-U6-Lmna sgRNA

    Plasmid

    #206979

    Purpose

    Expresses SauriABE8e by EFS promoter and sgRNA targeting murine Lmna c.1621T mutation by U6 promoter

    Depositor

    Yuxuan Guo

    Article

    Yang et al J Cell Mol Med. 2024 Feb;28(4):e18145. d

    Insert

    Lmna sgRNA
    

    Use

    AAV; Adenine base editor

    Tags

    Expression

    Mutation

    Promoter

    U6

    Available since

    Feb. 13, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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19. pAAV-cFOS-FRB-VP16-P2A-EGFP

    Plasmid

    #210510

    Purpose

    expresses cFOS-FRB-VP16 and EGFP component in rat hippocampal neuron cells

    Depositor

    Dongmin Lee

    Article

    Cui et al Nat Chem Biol. 2024 Mar;20(3):353-364. d

    Insert

    FRB-VP16-P2A-EGFP
    

    Use

    AAV

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    cFos

    Available since

    Jan. 26, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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20. pAAV-CMV-FLEXfrt-SaCas9-U6-sgNtsr1(guide_2)

    Plasmid

    #205417

    Purpose

    Mutagenesis of Ntsr1, second guide

    Depositor

    Larry Zweifel

    Insert

    Ntsr1 (Ntsr1 Mouse)
    

    Use

    AAV and CRISPR

    Tags

    Expression

    Mutation

    Promoter

    U6

    Available since

    Sept. 21, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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