We narrowed to 19,334 results for: Mut
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Plasmid#90424Purposeinduces dsDNA break within mouse Sf3b1 gene for subsequent homology-directed recombination and coding sequence mutagenesis at codon 700DepositorInsertmus Sf3b1 gRNA (Sf3b1 Mouse)
UseCRISPR; Guiderna encoding for gene editingExpressionMammalianPromoterU6Available SinceNov. 26, 2018AvailabilityAcademic Institutions and Nonprofits only -
pTE3328
Plasmid#107539PurposeExpresses As crRNA and human codon optimized AsCpf1(RR mutant) in mammalian cells.DepositorInsertsAs crRNA
hAsCpf1(RR mutant)
Tags3xHA, NLS, and SV40 NLSExpressionMammalianMutationS542R, K607RPromoterCMV and human U6Available SinceMarch 29, 2018AvailabilityAcademic Institutions and Nonprofits only -
pTE3329
Plasmid#107538PurposeExpresses Lb crRNA and human codon optimized LbCpf1(RR mutant) in mammalian cells.DepositorInsertsLb crRNA
hLbCpf1(RR mutant)
Tags3xHA, NLS, and SV40 NLSExpressionMammalianMutationG532R, K595RPromoterCMV and human U6Available SinceMarch 29, 2018AvailabilityAcademic Institutions and Nonprofits only -
pCEP4-myc-CXCR4-W161Y
Plasmid#98951PurposeMammalian expression plasmid for N-terminal myc-tagged human CXCR4 mutant W161YDepositorInsertCXCR4 (CXCR4 Human)
TagsSignal/leader sequence from Influenza A virus HA …ExpressionMammalianMutationW161Y: enhanced CXCL12 binding and signalingPromoterCMVAvailable SinceApril 24, 2018AvailabilityAcademic Institutions and Nonprofits only -
pCEP4-myc-CXCR4-W161H
Plasmid#98952PurposeMammalian expression plasmid for N-terminal myc-tagged human CXCR4 mutant W161HDepositorInsertCXCR4 (CXCR4 Human)
TagsSignal/leader sequence from Influenza A virus HA …ExpressionMammalianMutationW161H: enhanced CXCL12 binding and signalingPromoterCMVAvailable SinceApril 24, 2018AvailabilityAcademic Institutions and Nonprofits only -
pmCherry-3xNLS-OptoJNKi-dsm
Plasmid#89743PurposeExpression of light-regulated JNK inhibitor, mCherry-tagged, localised to nucleus, dark-state mutant photosensor (AsLov2Ja.C450A), inhibitor JIP11DepositorInsertNLS-OptoJNKi dark-state mutant
UseFluorescent proteinTagsmCherryExpressionMammalianMutationC450A mutation of AsLov2JalphaPromoterCMVAvailable SinceAug. 29, 2017AvailabilityAcademic Institutions and Nonprofits only -
pmCherry-3xNLS-OptoJNKi-lsm
Plasmid#89742PurposeExpression of light-regulated JNK inhibitor, mCherry-tagged, localised to nucleus, lit-state mutant photosensor (AsLov2Ja.I539E), inhibitor JIP11DepositorInsertNLS-OptoJNKi lit-state mutant
UseFluorescent proteinTagsmCherryExpressionMammalianMutationI539E mutation of AsLov2JalphaPromoterCMVAvailable SinceAug. 29, 2017AvailabilityAcademic Institutions and Nonprofits only -
pRS416 ATG5-E141D-HA-ATG12-ATG16
Plasmid#166851PurposeExpresses mutant E141D ATG5, HA-ATG12 ATG16 in yeast.DepositorAvailable SinceApril 5, 2021AvailabilityAcademic Institutions and Nonprofits only -
p53 S23A targeting vector
Plasmid#12167DepositorInsertp53 (Trp53 Mouse)
UseCre/LoxExpressionMammalianMutationSer23 mutation (S23A) in exon 2 and puromycin gen…Available SinceJune 30, 2006AvailabilityAcademic Institutions and Nonprofits only -
pCEP4-myc-CXCR4-H79Q
Plasmid#98953PurposeMammalian expression plasmid for N-terminal myc-tagged human CXCR4 mutant H79QDepositorInsertCXCR4 (CXCR4 Human)
TagsSignal/leader sequence from Influenza A virus HA …ExpressionMammalianMutationH79Q: enhanced CXCL12 binding and signalingPromoterCMVAvailable SinceApril 24, 2018AvailabilityAcademic Institutions and Nonprofits only -
pCDF1-S400F_RASA2-EF1-Puro
Plasmid#114098PurposeExpress mutant RASA2 in mamalian cellsDepositorInsertRASA2 (RASA2 Human)
UseLentiviralTagsFlagExpressionMammalianMutationS400FPromoterCMVAvailable SinceApril 10, 2019AvailabilityAcademic Institutions and Nonprofits only -
pTE3336
Plasmid#107541PurposeExpresses Mb crRNA and human codon optimized MbCpf1(RR mutant) in mammalian cells.DepositorInsertsMb crRNA
hMbCpf1(RR mutant)
Tags3xHA and NLSExpressionMammalianMutationN576R, K637RPromoterCMV and human U6Available SinceMarch 29, 2018AvailabilityAcademic Institutions and Nonprofits only -
pTE3333
Plasmid#107540PurposeExpresses Fn crRNA and human codon optimized FnCpf1(RR mutant) in mammalian cells.DepositorInsertsFn crRNA
hFnCpf1(RR mutant)
Tags3xHA and NLSExpressionMammalianMutationN607R, K671RPromoterCMV and human U6Available SinceMarch 29, 2018AvailabilityAcademic Institutions and Nonprofits only -
pcDNA3-Flag-NSF/S647A
Plasmid#74938PurposeMammalian expression of human NSF mutant S647A (mutation in the D2 domain of the protein)DepositorInsertNSF (NSF Human)
TagsFLAGExpressionMammalianMutationS647A (mutation in the D2 domain of the protein)PromoterCMVAvailable SinceApril 20, 2016AvailabilityAcademic Institutions and Nonprofits only -
pEGFP-C1_N-NLS_L704A_F707A_F708A POLH
Plasmid#221873PurposeExpresses PIP box-mutated POLH with an N-terminal NLS-GFP tag in mammalian cellsDepositorAvailable SinceFeb. 23, 2026AvailabilityAcademic Institutions and Nonprofits only -
pCMV6-AN-DDK_K682A POLH
Plasmid#221862PurposeExpresses POLH mutated at K682A with a FLAG tag in mammalian cellsDepositorInsertPOLH (POLH Human)
TagsFLAGExpressionMammalianMutationPOLH K682A. Coding sequence has been optimised fo…PromoterCMVAvailable SinceFeb. 23, 2026AvailabilityAcademic Institutions and Nonprofits only -
pCMV6-AN-DDK_K709A POLH
Plasmid#221863PurposeExpresses POLH mutated at K709A with a FLAG tag in mammalian cellsDepositorInsertPOLH (POLH Human)
TagsFLAGExpressionMammalianMutationPOLH K709A. Coding sequence has been optimised fo…PromoterCMVAvailable SinceFeb. 23, 2026AvailabilityAcademic Institutions and Nonprofits only -
pKlab264-pcDNA3-BRCA1(1314-end)-M1783T-V5-3xFLAG
Plasmid#249017PurposeThis plasmid expresses the C-terminally 3x-FLAG tagged BRCT domain that contains the M1783T mutationDepositorInsertBRCA1(1314aa-end) (BRCA1 Human)
Tags3x-FLAG-V5ExpressionMammalianMutationM1783TPromoterCMV PromoterAvailable SinceJan. 22, 2026AvailabilityAcademic Institutions and Nonprofits only -
pKlab211-pcDNA3-BRCA1(1314-end)-L1705R-V5-3xFLAG
Plasmid#249015PurposeThis plasmid expresses the C-terminally 3x-FLAG tagged BRCT domain that contains the L1705R mutationDepositorInsertBRCA1(1314aa-end) (BRCA1 Human)
Tags3x-FLAG-V5ExpressionMammalianMutationL1705RPromoterCMV PromoterAvailable SinceJan. 21, 2026AvailabilityAcademic Institutions and Nonprofits only -
pKlab240-pcDNA3-BRCA1(1314-end)-Y1845D-V5-3xFLAG
Plasmid#249016PurposeThis plasmid expresses the C-terminally 3x-FLAG tagged BRCT domain that contains the Y1845D mutationDepositorInsertBRCA1(1314aa-end) (BRCA1 Human)
Tags3x-FLAG-V5ExpressionMammalianMutationY1845DPromoterCMV PromoterAvailable SinceJan. 21, 2026AvailabilityAcademic Institutions and Nonprofits only