We narrowed to 4,387 results for: DUR

1. pMX-53BP1(1-1710) 3LA

   Plasmid

   #185698

   Purpose

   Mammalian Expression, Retroviral vector that encodes a 3LA mutant of 53BP1 that disrupts three RIF1-binding motifs and abolishes the 53BP1-dependent recruitment of RIF1 to DNA double-strand breaks.

   Depositor

   Daniel Durocher

   Article

   Setiaputra et al Mol Cell. 2022 Apr 7;82(7):1359-1371.e9.

   Insert

   53BP1(1-1710) 3LA (TP53BP1 Human)
   

   Use

   Retroviral

   Tags

   Flag tag, HA tag, and tetracysteine tag

   Expression

   Mammalian

   Mutation

   L175A, L517A, and L693A

   Promoter

   SV40

   Available since

   July 7, 2022

   Availability

   Industry, Academic Institutions, and Nonprofits

   

   Enlarge

2. pMX-53BP1(1-1710) 3LA7A

   Plasmid

   #185707

   Purpose

   Mammalian Expression, Retroviral vector that encodes 7A and 3LA mutant of 53BP1. Prevents shieldin and RIF1 recruitment to sites of double-strand breaks and disrupts 53BP1 activity.

   Depositor

   Daniel Durocher

   Article

   Setiaputra et al Mol Cell. 2022 Apr 7;82(7):1359-1371.e9.

   Insert

   53BP1(1-1710) 3LA7A (TP53BP1 Human)
   

   Use

   Retroviral

   Tags

   Flag tag, HA tag, and tetracysteine tag

   Expression

   Mammalian

   Mutation

   T302A, S452A, S523A, S543A, S625A, S784A, and S89…

   Promoter

   SV40

   Available since

   July 1, 2022

   Availability

   Industry, Academic Institutions, and Nonprofits

   

   Enlarge

3. pcDNA3-Flag::UbvG08 P69L, L70V, I44A, deltaGG

   Plasmid

   #74940

   Purpose

   Ubiquitin variant with mutations L69P and V70L reverted to wild type (i53-DM mutant)

   Depositor

   Daniel Durocher

   Article

   Canny et al Nat Biotechnol. 2018 Jan;36(1):95-102. d

   Insert

   Ubiquitin
   

   Use

   Tags

   Flag

   Expression

   Mammalian

   Mutation

   UbvG08 with I44A, P69L, and L70V mutations and no…

   Promoter

   CMV

   Available since

   May 13, 2016

   Availability

   Industry, Academic Institutions, and Nonprofits

   

   Enlarge

4. CD59-CD4d3+4-bio

   Plasmid

   #73117

   Purpose

   EXPRESs plasmid for human erythrocyte surface proteins encoding CD59 with rat CD4d3+4-bio

   Depositor

   Gavin Wright

   Article

   Crosnier et al Nature. 2011 Nov 9;480(7378):534-7. doi:

   Insert

   CD59 glycoprotein (CD59, MIC11 Human)
   

   Use

   Tags

   biotinylation peptide and ratCD4d3+4

   Expression

   Mammalian

   Mutation

   Promoter

   CMV

   Available since

   March 28, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

5. pIRES2-CMV-nAChRb2(E61C)-IRES-GFP

   Plasmid

   #164779

   Purpose

   cysteine mutated nAChR beta2 subunit (E61C) for the attachment of a photoswitchable tethered ligand

   Depositor

   Alexandre Mourot

   Article

   Durand-de Cuttoli et al Elife. 2018 Sep 4;7. pii: 37487. doi: 10

   Insert

   nAChR b2 E61C - IRES- GFP (Chrnb2 Mouse)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   E61C

   Promoter

   CMV

   Available since

   April 6, 2021

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

6. pHIV(T9)-DERA-sgresis

   Plasmid

   #222622

   Purpose

   Lentiviral vector that expresses sgRNA resistant DERA in mammalian cells

   Depositor

   Daniel Durocher

   Article

   Zhao et al Mol Cell. 2023 Aug 3;83(15):2792-2809.e9

   Insert

   DERA (DERA Human)
   

   Use

   Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   EF1a

   Available since

   Aug. 19, 2024

   Availability

   Industry, Academic Institutions, and Nonprofits

   

   Enlarge

7. pcDNA5-FRT/T0-EGFP-GNB1L

   Plasmid

   #222621

   Purpose

   Mammalian expression vector of flag-tagged GNB1L

   Depositor

   Daniel Durocher

   Article

   Zhao et al Mol Cell. 2023 Aug 3;83(15):2792-2809.e9

   Insert

   GNB1L (GNB1L Human)
   

   Use

   Tags

   EGFP

   Expression

   Mammalian

   Mutation

   Promoter

   CMV

   Available since

   Aug. 19, 2024

   Availability

   Industry, Academic Institutions, and Nonprofits

   

   Enlarge

8. pHIV-NAT-FLAG-CIP2A FL (sg2R)

   Plasmid

   #222624

   Purpose

   Lentiviral vector that expresses Flag-tagged sgRNA resistant CIP2A in mammalian cells

   Depositor

   Daniel Durocher

   Article

   Adam et al Nat Cancer. 2021 Dec;2(12):1357-1371. do

   Insert

   CIP2A (CIP2A Human)
   

   Use

   Lentiviral

   Tags

   Flag

   Expression

   Mammalian

   Mutation

   Promoter

   EF-1-alpha promoter

   Available since

   July 18, 2024

   Availability

   Industry, Academic Institutions, and Nonprofits

   

   Enlarge

9. pDNA5-FRT/TO-FLAG-TONSL

   Plasmid

   #221011

   Purpose

   mammalian expression vector of Flag tagged TONSL siRNA resistant

   Depositor

   Daniel Durocher

   Article

   O'Donnell et al Mol Cell. 2010 Nov 24;40(4):619-31. doi:

   Insert

   TONSL (TONSL Human)
   

   Use

   Tags

   Flag

   Expression

   Mammalian

   Mutation

   silent mutations in TONSL: 5’-gaATtAgaTCtaTCGatga…

   Promoter

   CMV

   Available since

   June 24, 2024

   Availability

   Industry, Academic Institutions, and Nonprofits

   

   Enlarge

10. pDNA5-FRT/TO-eGFP-TONSL

    Plasmid

    #221012

    Purpose

    mammalian expression vector of eGFP tagged TONSL siRNA resistant

    Depositor

    Daniel Durocher

    Article

    O'Donnell et al Mol Cell. 2010 Nov 24;40(4):619-31. doi:

    Insert

    TONSL (TONSL Human)
    

    Use

    Tags

    eGFP

    Expression

    Mammalian

    Mutation

    silent mutations in TONSL: 5’-gaATtAgaTCtaTCGatga…

    Promoter

    CMV

    Available since

    June 24, 2024

    Availability

    Industry, Academic Institutions, and Nonprofits

    

    Enlarge

11. pcDNA5-FRT/TO-FLAG-SHLD2

    Plasmid

    #114117

    Purpose

    Expresses N-terminally tagged FLAG-SHLD2 in mammalian cells

    Depositor

    Daniel Durocher

    Article

    Noordermeer et al Nature. 2018 Aug;560(7716):117-121. doi:

    Insert

    SHLD2 (SHLD2 Human)
    

    Use

    Genomic integration, tetracycline inducible

    Tags

    FLAG

    Expression

    Mammalian

    Mutation

    Promoter

    CMV/TetO2

    Available since

    Aug. 28, 2018

    Availability

    Industry, Academic Institutions, and Nonprofits

    

    Enlarge

12. pCW-eGFP-FHA-SHLD2

    Plasmid

    #114121

    Purpose

    Lentiviral vector for inducible expression of N-terminally tagged eGFP-RNF8 FHA domain-SHLD2; 53BP1-independent recruitment to damaged chromatin

    Depositor

    Daniel Durocher

    Article

    Noordermeer et al Nature. 2018 Aug;560(7716):117-121. doi:

    Insert

    SHLD2 (SHLD2 Human)
    

    Use

    Lentiviral; Doxycycline inducible

    Tags

    RNF8 FHA domain (aa 2-160) and eGFP

    Expression

    Mammalian

    Mutation

    Promoter

    TRE promoter, Tet ON

    Available since

    Aug. 28, 2018

    Availability

    Industry, Academic Institutions, and Nonprofits

    

    Enlarge

13. pDEST 3xFlag-pcDNA5-FRT/T0-53BP1 28A

    Plasmid

    #52505

    Purpose

    mammalian expression vector of 53BP1 28A mutant

    Depositor

    Daniel Durocher

    Article

    Escribano-Diaz et al Mol Cell. 2013 Mar 7;49(5):872-83. doi:

    Insert

    53BP1 28A (TP53BP1 Human)
    

    Use

    Tags

    Flag

    Expression

    Mammalian

    Mutation

    All 28 SQ/TQ motifs in N-term of 53BP1 have been …

    Promoter

    Available since

    April 10, 2015

    Availability

    Industry, Academic Institutions, and Nonprofits

    

    Enlarge

14. pCW-eGFP-SHLD2-m1

    Plasmid

    #114120

    Purpose

    Lentiviral vector for inducible expression of N-terminally tagged eGFP-SHLD2, m1 mutant

    Depositor

    Daniel Durocher

    Article

    Noordermeer et al Nature. 2018 Aug;560(7716):117-121. doi:

    Insert

    SHLD2 (m1 mutant) (SHLD2 Human)
    

    Use

    Lentiviral; Doxycycline inducible

    Tags

    eGFP

    Expression

    Mammalian

    Mutation

    W489A, F494A, W495A mutations introduced

    Promoter

    TRE promoter, Tet ON

    Available since

    Aug. 28, 2018

    Availability

    Industry, Academic Institutions, and Nonprofits

    

    Enlarge

15. pCW-eGFP-FHA

    Plasmid

    #114129

    Purpose

    Lentiviral vector for inducible expression of eGFP-RNF8 FHA domain fusion; 53BP1-independent recruitment to damaged chromatin

    Depositor

    Daniel Durocher

    Article

    Noordermeer et al Nature. 2018 Aug;560(7716):117-121. doi:

    Insert

    RNF8 FHA domain (amino acids 2-160) (RNF8 Human)
    

    Use

    Lentiviral; Doxycycline inducible

    Tags

    eGFP

    Expression

    Mammalian

    Mutation

    aa 2-160

    Promoter

    TRE promoter, Tet ON

    Available since

    Aug. 28, 2018

    Availability

    Industry, Academic Institutions, and Nonprofits

    

    Enlarge

16. pcDNA5-FRT/T0-Flag-CIP2A

    Plasmid

    #222623

    Purpose

    mammalian expression vector of Flag-tagged CIP2A

    Depositor

    Daniel Durocher

    Article

    Adam et al Nat Cancer. 2021 Dec;2(12):1357-1371. do

    Insert

    CIP2A (CIP2A Human)
    

    Use

    Tags

    Flag

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    July 18, 2024

    Availability

    Industry, Academic Institutions, and Nonprofits

    

    Enlarge

17. pGLUE-SHLD2

    Plasmid

    #114118

    Purpose

    Expresses N-terminally tagged Streptag-HA-CBP-SHLD2 in mammalian cells

    Depositor

    Daniel Durocher

    Article

    Noordermeer et al Nature. 2018 Aug;560(7716):117-121. doi:

    Insert

    SHLD2 (SHLD2 Human)
    

    Use

    Tags

    HA tag, Streptavidin-binding tag (Streptag), and …

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    Aug. 28, 2018

    Availability

    Industry, Academic Institutions, and Nonprofits

    

    Enlarge

18. pDEST-FRT/TO-eGFP-REV7

    Plasmid

    #114128

    Purpose

    Expresses N-terminally tagged eGFP-REV7 in mammalian cells

    Depositor

    Daniel Durocher

    Article

    Noordermeer et al Nature. 2018 Aug;560(7716):117-121. doi:

    Insert

    REV7 (MAD2L2 Human)
    

    Use

    Genomic integration, tetracycline inducible

    Tags

    eGFP

    Expression

    Mammalian

    Mutation

    Promoter

    CMV/TetO2

    Available since

    Aug. 15, 2018

    Availability

    Industry, Academic Institutions, and Nonprofits

    

    Enlarge

19. pDEST-FRT/TO-3xFLAG-REV7

    Plasmid

    #114127

    Purpose

    Expresses N-terminally tagged 3x FLAG-REV7 in mammalian cells

    Depositor

    Daniel Durocher

    Article

    Noordermeer et al Nature. 2018 Aug;560(7716):117-121. doi:

    Insert

    REV7 (MAD2L2 Human)
    

    Use

    Genomic integration, tetracycline inducible

    Tags

    3xFLAG

    Expression

    Mammalian

    Mutation

    Promoter

    CMV/TetO2

    Available since

    Aug. 16, 2018

    Availability

    Industry, Academic Institutions, and Nonprofits

    

    Enlarge

20. pCW-eGFP-FHA-SHLD2-m1

    Plasmid

    #114122

    Purpose

    Lentiviral vector for inducible expression of N-terminally tagged eGFP-RNF8 FHA domain-SHLD2, m1 mutant; 53BP1-independent recruitment to damaged chromatin

    Depositor

    Daniel Durocher

    Article

    Noordermeer et al Nature. 2018 Aug;560(7716):117-121. doi:

    Insert

    SHLD2 (m1 mutant) (SHLD2 Human)
    

    Use

    Lentiviral; Doxycycline inducible

    Tags

    RNF8 FHA domain (aa 2-160) and eGFP

    Expression

    Mammalian

    Mutation

    W489A, F494A, W495A mutations introduced

    Promoter

    TRE promoter, Tet ON

    Available since

    Aug. 28, 2018

    Availability

    Industry, Academic Institutions, and Nonprofits

    

    Enlarge