We narrowed to 27,291 results for: Tat

1. Rb379-928/C706F-pGex2TK

   Plasmid

   #21750

   Depositor

   William Kaelin

   Article

   Kaelin et al Cell. 1992 Jul 24. 70(2):351-64.

   Insert

   Rb (RB1 Human)
   

   Use

   Tags

   GST

   Expression

   Bacterial

   Mutation

   deletion mutant ORF contains aa 379-928 of wt Rb …

   Promoter

   Available since

   Sept. 30, 2009

   Availability

   Academic Institutions and Nonprofits only

   

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2. pMiR-CIP2A-miR-375-mutA-E

   Plasmid

   #53754

   Purpose

   Luciferase reporter assay for CIP2A with point mutation on miR-375 binding sites

   Depositor

   Edward Chan

   Article

   Jung et al Mol Biol Cell. 2013 Jun;24(11):1638-48,

   Insert

   CIP2A (CIP2A Human)
   

   Use

   Luciferase

   Tags

   Expression

   Mutation

   Mutation on miR-375 binding site A-E (refer to ci…

   Promoter

   Available since

   July 2, 2014

   Availability

   Academic Institutions and Nonprofits only

3. pENTR2b-ITGB1(YYFF)-mRuby2

   Plasmid

   #215447

   Purpose

   Gateway entry vector with integrin beta1 NPxY mutant (YYFF) tagged with mRuby2

   Depositor

   Johanna Ivaska

   Article

   Conway et al Nat Cell Biol. 2025 May 26. doi: 10.1038

   Insert

   ITGB1 (ITGB1 Human)
   

   Use

   Gateway entry vector

   Tags

   mRuby2

   Expression

   Mutation

   Mutations in the NPxY sites Y783F, Y795F; Silent …

   Promoter

   none

   Available since

   May 29, 2025

   Availability

   Industry, Academic Institutions, and Nonprofits

   

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4. pPB.DEST-ITGB1(YYFF)-mRuby2

   Plasmid

   #215449

   Purpose

   Piggybac expression vector with integrin beta1 NPxY mutant (YYFF) tagged with mRuby2

   Depositor

   Johanna Ivaska

   Article

   Conway et al Nat Cell Biol. 2025 May 26. doi: 10.1038

   Insert

   ITGB1 (ITGB1 Human)
   

   Use

   Transposon-based stable expression

   Tags

   mRuby2

   Expression

   Mammalian

   Mutation

   Mutations in the NPxY sites Y783F, Y795F; Silent …

   Promoter

   CAG

   Available since

   May 29, 2025

   Availability

   Industry, Academic Institutions, and Nonprofits

   

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5. 7AA-aSyn-pRK172

   Plasmid

   #236197

   Purpose

   This plasmid expresses human α-synuclein with a 7-amino acid insertion (MAAAEKT) in the pRK172 backbone for bacterial expression in E. coli. The insertion corresponds to the JOS mutation.

   Depositor

   Sjors Scheres, Yang Yang

   Article

   Yang et al Acta Neuropathol. 2023 May;145(5):561-57

   Insert

   SNCA (SNCA Human)
   

   Use

   Tags

   Expression

   Bacterial

   Mutation

   insertion os MAAAEKT at residue 22

   Promoter

   Available since

   April 23, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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6. hnRNPA1_allW_D262V-FLAG-IRES-eGFP

   Plasmid

   #234621

   Purpose

   Mammalian expression of full-length hnRNPA1 D262V with all aromatic amino acids in the C-terminal LCD mutated to W keeping the hexapeptide fibril core (SYNDFG) and the PY-NLS intact.

   Depositor

   Tanja Mittag

   Article

   Das et al bioRxiv [Preprint]. 2024 Mar 3:2024.02.2

   Insert

   hnRNPA1 allW D262V (HNRNPA1 Human)
   

   Use

   Tags

   FLAG

   Expression

   Mammalian

   Mutation

   Famillial ALS mutation D262V, all aromatic amino …

   Promoter

   CMV

   Available since

   March 11, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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7. Cdk13_intron4_sg3_pX330

   Plasmid

   #127340

   Purpose

   sgRNA that cuts within intron 4 of mouse CDK13 genomic locus- guide #3

   Depositor

   Phil Sharp

   Article

   Insco et al Science. 2023 Apr 21;380(6642):eabn7625.

   Insert

   Mouse Cdk13 Intron 4 Targeting sgRNA (Cdk13 Mouse)
   

   Use

   CRISPR and Mouse Targeting

   Tags

   Expression

   Mutation

   Promoter

   U6 Promoter

   Available since

   Dec. 11, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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8. pcDNA3.1+FLAG-KrascomQ61R

   Plasmid

   #206845

   Purpose

   To express mouse Kras encoded by common mouse codons (to increase expression) and with a Q61R mutation with an N-terminal FLAG tag.

   Depositor

   Christopher Counter

   Article

   Le Roux et al Elife. 2022 Sep 7;11:e75715. doi: 10.755

   Insert

   Kras (Kras Mouse)
   

   Use

   Tags

   FLAG

   Expression

   Mammalian

   Mutation

   Codons altered to most optimum based on mouse cod…

   Promoter

   Available since

   July 31, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

9. pMXS-IRES-BLAST flag-CAD T456A S1406A S1859A

   Plasmid

   #169826

   Purpose

   Expresses C-terminal flag-tagged CAD with mutation of reported S6K, PKA, and Erk1/2 phosphorylation site

   Depositor

   Richard Possemato

   Article

   Shin et al Nat Metab. 2023 Feb 6. doi: 10.1038/s422

   Insert

   CAD (CAD Human)
   

   Use

   Retroviral

   Tags

   Flag tag

   Expression

   Mammalian

   Mutation

   T456A S1406A S1859A; TCCC -> AGTC silent mutat…

   Promoter

   Available since

   July 15, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. pMXS-IRES-BLAST flag-CAD R2187A

    Plasmid

    #169827

    Purpose

    Expresses C-terminal flag-tagged CAD with mutation at reported trimerization interface of the ATCase domain of CAD

    Depositor

    Richard Possemato

    Article

    Shin et al Nat Metab. 2023 Feb 6. doi: 10.1038/s422

    Insert

    CAD (CAD Human)
    

    Use

    Retroviral

    Tags

    Flag tag

    Expression

    Mammalian

    Mutation

    R2187A, T456A S1406A S1859A; TCCC -> AGTC sile…

    Promoter

    Available since

    July 15, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

11. pMXS-IRES-BLAST flag-CAD H1734A H1741A

    Plasmid

    #169830

    Purpose

    Expresses C-terminal flag-tagged CAD with mutations at reported dimerization interface of the DHOase domain

    Depositor

    Richard Possemato

    Article

    Shin et al Nat Metab. 2023 Feb 6. doi: 10.1038/s422

    Insert

    CAD (CAD Human)
    

    Use

    Retroviral

    Tags

    Flag tag

    Expression

    Mammalian

    Mutation

    H1734A H1741A; TCCC -> AGTC silent mutations a…

    Promoter

    Available since

    July 15, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

12. pMXS-IRES-BLAST flag-CAD T456A S1406A

    Plasmid

    #169823

    Purpose

    Expresses C-terminal flag-tagged CAD with mutation of reported Erk1/2 and PKA phosphorylation site

    Depositor

    Richard Possemato

    Article

    Shin et al Nat Metab. 2023 Feb 6. doi: 10.1038/s422

    Insert

    CAD (CAD Human)
    

    Use

    Retroviral

    Tags

    Flag tag

    Expression

    Mammalian

    Mutation

    T456A S1406A; TCCC -> AGTC silent mutations at…

    Promoter

    Available since

    July 15, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

13. pMXS-IRES-BLAST flag-CAD T456A S1859A

    Plasmid

    #169824

    Purpose

    Expresses C-terminal flag-tagged CAD with mutation of reported Erk1/2 and S6K phosphorylation site

    Depositor

    Richard Possemato

    Article

    Shin et al Nat Metab. 2023 Feb 6. doi: 10.1038/s422

    Insert

    CAD (CAD Human)
    

    Use

    Retroviral

    Tags

    Flag tag

    Expression

    Mammalian

    Mutation

    T456A S1859A; TCCC -> AGTC silent mutations at…

    Promoter

    Available since

    July 15, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. pLX304-BCL-XL-499/500R

    Plasmid

    #203575

    Purpose

    Expresses V5-tagged BCL-XL with resistance to shRNA (TRCN0000033499, TRCN0000033500) in mammalian cells.

    Depositor

    Abhishek Chakraborty

    Article

    Grubb et al Clin Cancer Res. 2022 Nov 1;28(21):4689-

    Insert

    BCL2L1 (BCL2L1 Human)
    

    Use

    Lentiviral

    Tags

    V5-tagged

    Expression

    Mammalian

    Mutation

    silent point mutations to make resistant shRNA 49…

    Promoter

    CMV

    Available since

    Feb. 22, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. pmirGLO-3'UTR mouse Il13 mutDRACH

    Plasmid

    #207130

    Purpose

    Luciferase vector containing 3'UTR for mouse Il13 with mutated DRACH sites

    Depositor

    Silvia Monticelli

    Article

    Leoni et al Nat Commun. 2023 Jun 29;14(1):3862. doi:

    Insert

    Interleukin 13 (Il13) 3'UTR (Il13 Mouse)
    

    Use

    Luciferase

    Tags

    Expression

    Mammalian

    Mutation

    TGAGGAGAGACCATCCCTGGGCATCTCAGCTGTGGACTCATTTTCCTTT…

    Promoter

    Available since

    Dec. 14, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. pUb FLAG-Mts D85N

    Plasmid

    #208403

    Purpose

    Expresses FLAG-tagged Drosophila mts protein with D85N mutation

    Depositor

    Jeremy Wilusz

    Article

    Fujiwara et al Mol Cell. 2023 Nov 14:S1097-2765(23)0090

    Insert

    microtubule star (mts Fly)
    

    Use

    Tags

    3xFLAG

    Expression

    Insect

    Mutation

    D85N

    Promoter

    Ubi-p63e

    Available since

    Dec. 8, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. pUb FLAG-Mts H59Q

    Plasmid

    #208402

    Purpose

    Expresses FLAG-tagged Drosophila mts protein with H59Q mutation

    Depositor

    Jeremy Wilusz

    Article

    Fujiwara et al Mol Cell. 2023 Nov 14:S1097-2765(23)0090

    Insert

    microtubule star (mts Fly)
    

    Use

    Tags

    3xFLAG

    Expression

    Insect

    Mutation

    H59Q

    Promoter

    Ubi-p63e

    Available since

    Dec. 8, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. pUb FLAG-Mts H241A

    Plasmid

    #208404

    Purpose

    Expresses FLAG-tagged Drosophila mts protein with H241A mutation

    Depositor

    Jeremy Wilusz

    Article

    Fujiwara et al Mol Cell. 2023 Nov 14:S1097-2765(23)0090

    Insert

    microtubule star (mts Fly)
    

    Use

    Tags

    3xFLAG

    Expression

    Insect

    Mutation

    H241A

    Promoter

    Ubi-p63e

    Available since

    Dec. 8, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. pcDNA3_ATP10B-G671R-N865K

    Plasmid

    #203699

    Purpose

    expresses ATP10B with the pathogenic mutations G671R and N865K

    Depositor

    Peter Vangheluwe

    Article

    Martin et al Acta Neuropathol. 2020 Jun;139(6):1001-1

    Insert

    ATP10B (ATP10B Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    G671R, N865K

    Promoter

    Available since

    Nov. 6, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. pQCXIZ GFP PODXL delta PBM

    Plasmid

    #202415

    Purpose

    Expression of GFP-tagged PODXL PDZ-binding motif mutation (PBM; doesn't bind NHERF1/2)

    Depositor

    David Bryant

    Article

    Roman-Fernandez et al Sci Adv. 2023 Feb 3;9(5):eabq1858. doi:

    Insert

    PODXL (PODXL Human)
    

    Use

    Lentiviral

    Tags

    GFP

    Expression

    Mutation

    Lacking DTHL

    Promoter

    Available since

    Aug. 1, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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