We narrowed to 65 results for: Channelrhodopsin2
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Plasmid#232601PurposePan-neuronal expression of opsin 'ChR2(H134R)', regulated by rab-3 promoter and unc-54 3' UTRDepositorInsertChannelrhodopsin2
ExpressionWormMutationH134RAvailable SinceFeb. 20, 2025AvailabilityAcademic Institutions and Nonprofits only -
pAAV.EF1a.ChR2-YFP.WPRE.hGH
Plasmid#100056PurposeAAV expression of ChR2 fused to YFP driven byEF1a promoter for optogenetic activationDepositorInsertChR2
UseAAVTagsEYFPExpressionMammalianPromoterEF1aAvailable SinceJan. 31, 2018AvailabilityAcademic Institutions and Nonprofits only -
pLenti-CaMKIIa-hChR2(C128S)-EYFP-WPRE
Plasmid#20294PurposeLentiviral expression of ChR2 (C128S) Step Function Opsin (SFO) fused to EYFP, for bi-stable optogenetic excitationDepositorInsertchannelrhodopsin-2
UseLentiviralTagsEYFPExpressionMammalianMutationchanged Cysteine 128 to SerineAvailable SinceMay 13, 2009AvailabilityAcademic Institutions and Nonprofits only -
tol2-CAG::ChR2-YFP
Plasmid#59740PurposeOptogenetic excitation of ES cell-derived neurons (and other cells, such as muscle)DepositorInsertChannelrhodopsin-2
TagsYFPExpressionMammalianMutationH134RPromoterCAGAvailable SinceOct. 2, 2014AvailabilityAcademic Institutions and Nonprofits only -
pAAV EF1a DIO iChloC 2A dsRed
Plasmid#70762PurposeAn improved chloride-conducting channelrhodopsin for light-induced inhibition of neuronal activity in vivo. Cre inducible expression (double floxed inversed ORF)DepositorInsertsChannelrhodopsin-2
red fluorescent protein
UseAAVExpressionMammalianMutationE83Q,E90R,E101S,D156N,T159CPromoterEF1aAvailable SinceJan. 7, 2016AvailabilityAcademic Institutions and Nonprofits only -
plenti2-EF1a-ChR2-EYFP-WRPE
Plasmid#125255Purpose3rd gen lentiviral expression of ChR2 with mutation fused to EYFP driven by EF1a promoter for optogenetic activationDepositorInserthChR2
UseLentiviralTagsEYFPExpressionMammalianAvailable SinceJan. 14, 2020AvailabilityAcademic Institutions and Nonprofits only -
pAAV-TRE-flex-ChR2 (E123T/T159C)-EYFP
Plasmid#135176PurposeAAV expression of TRE(TRE3G)-driven, Cre-dependent, humanized channelrhodopsin E123T/T159C mutant fused to EYFP for optogenetic activation.DepositorInsertshChR2
TRE3G
UseAAV and Cre/LoxTagsEYFP (C terminal on insert)ExpressionMammalianMutationE123T and T159CPromoterTRE3GAvailable SinceJan. 10, 2020AvailabilityAcademic Institutions and Nonprofits only -
pAAV CaMKIIa iChloC 2A tDimer
Plasmid#66709PurposeChloride-conducting Channelrhodopsin with neuron-specific promoter, plus red fluorescent proteinDepositorInsertsChannelrhodopsin-2
red fluorescent protein
UseAAVExpressionMammalianMutationE83Q,E90R,E101S,D156N,T159CPromoterCaMKIIaAvailable SinceOct. 16, 2015AvailabilityAcademic Institutions and Nonprofits only -
pRK010
Plasmid#69874Purposeexpression of Channelrhodopsin-2 XXL (extra high expression and long open state, D156C) mutantDepositorInsertChannelrhodopsin-2
UseUnspecifiedMutationD156C (XXL)PromoterDrosophila Hsp70Available SinceJune 24, 2022AvailabilityAcademic Institutions and Nonprofits only -
pAAV Syn ChR E90R-T159C 2A tDimer
Plasmid#52495PurposeHistorical plasmid. For inhibition of neuronal activity, note that Addgene Plasmid #66709 is a light-gated chloride channel with improved anion selectivity (iChloC)DepositorInsertsChannelrhodopsin-2
red fluorescent protein
UseAAVExpressionMammalianMutationE90R, T159CPromoterhuman synapsin-1 and ribosomal skip sequenceAvailable SinceApril 16, 2014AvailabilityAcademic Institutions and Nonprofits only -
CAG:: ChR2HA-2a-hM4D
Plasmid#52520PurposeCo-expresses HA tagged channelrhodopsin and hM4D (Gi)DepositorInsertChR2-2a-hM4D
Tags2xHA on ChR2ExpressionMammalianPromoterCAGAvailable SinceMay 9, 2014AvailabilityAcademic Institutions and Nonprofits only -
pRK011
Plasmid#69875Purposeexpression of Channelrhodopsin-2 T159C mutantDepositorInsertChannelrhodopsin-2
UseUnspecifiedMutationT159CPromoterDrosophila Hsp70Available SinceJune 24, 2022AvailabilityAcademic Institutions and Nonprofits only -
AAV-CAG::FLEX-rev:: ChR2HA-2a-hM4D
Plasmid#52521PurposeCo-expresses HA tagged channelrhodopsin and hM4D (Gi) from a Cre-dependent virusDepositorInsertChR2-2a-hM4D
UseAAV and Cre/LoxTags2xHA on ChR2PromoterCBAAvailable SinceJune 10, 2014AvailabilityAcademic Institutions and Nonprofits only -
p-mCherry-N1-iChloC
Plasmid#85467Purposeimproved slowChloC artificial anion conducting ChR. Codon optimized for mammalian expression (human/mouse)DepositorInsertiChloC
TagsmCherryExpressionMammalianMutationE83Q, E90R, E101S, T159C, D156NPromoterCMV (+enhancer)Available SinceJan. 26, 2017AvailabilityAcademic Institutions and Nonprofits only -
pAAV Syn ChR E90R-D156N-T159C 2A tDimer
Plasmid#52494PurposeHistorical plasmid. For inhibition of neuronal activity, note that Addgene Plasmid #66709 is a light-gated chloride channel with improved anion selectivity (iChloC)DepositorInsertsChannelrhodopsin-2
red fluorescent protein
UseAAVExpressionMammalianMutationE90R, D156N, T159CPromoterhuman synapsin-1 and ribosomal skip sequenceAvailable SinceApril 7, 2014AvailabilityAcademic Institutions and Nonprofits only -
p-mCherry-N1-ChloC
Plasmid#85461PurposeHistorical plasmid. For inhibition of neuronal activity, #66709 is a light-gated chloride channel with improved anion selectivity (iChloC)DepositorInsertChloC
TagsmCherryExpressionMammalianMutationE90R, T159CPromoterCMV (+enhancer)Available SinceJan. 26, 2017AvailabilityAcademic Institutions and Nonprofits only -
p-mCherry-N1-slowChloC
Plasmid#85462PurposeHistorical plasmid. For inhibition of neuronal activity, #66709 is a light-gated chloride channel with improved anion selectivity (iChloC)DepositorInsertslowChloC
TagsmCherryExpressionMammalianMutationE90R, T159C, D156NPromoterCMV (+enhancer)Available SinceJan. 26, 2017AvailabilityAcademic Institutions and Nonprofits only -
VV201: ChR2(C128S)-eGFP in fubi
Plasmid#58510PurposeExpresses channelrhodopsin-2 with the C128S (step function opsin) mutation fused to eGFP under the ubiquitin promoterDepositorInsertChR2(C128S)-eGFP
UseLentiviralTagseGFPExpressionMammalianMutationChanged Cysteine 128 to SerinePromoterUbiquitinAvailable SinceNov. 5, 2014AvailabilityAcademic Institutions and Nonprofits only -
hSyn1-FLEX-hChR2-tdtomato
Plasmid#41015DepositorInsertChannelrhodopsin-2
UseAdenoviralTagstdtomatoExpressionMammalianMutationcodon-optimized (human)PromotersynapsinAvailable SinceNov. 6, 2012AvailabilityAcademic Institutions and Nonprofits only -
pLenti-CaMKIIa-hChR2(C128A)-EYFP-WPRE
Plasmid#20293PurposeLentiviral expression of ChR2 (C128A) Step Function Opsin (SFO) fused to EYFP, for bi-stable optogenetic excitationDepositorInsertchannelrhodopsin-2
UseLentiviralTagsEYFPExpressionMammalianMutationchanged Cysteine 128 to AlanineAvailable SinceMay 13, 2009AvailabilityAcademic Institutions and Nonprofits only