59,540 results

1. HER2 CA (V659E)

   Plasmid

   #16259

   Depositor

   Mien-Chie Hung

   Article

   Li et al Cancer Cell. 2004 Nov . 6(5):459-69.

   Insert

   HER2 (ERBB2 Human)
   

   Expression

   Mammalian

   Mutation

   Constitutively active: V659E

   Available Since

   Nov. 30, 2007

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

2. human MMP-2 promoter

   Plasmid

   #53432

   Purpose

   promoter activity study

   Depositor

   Etty Benveniste

   Article

   Qin et al J Biol Chem. 1999 Oct 8;274(41):29130-7.

   Insert

   MMP2 promoter (MMP2 Human)
   

   Use

   Luciferase

   Tags

   luciferase

   Expression

   Mammalian

   Promoter

   MMP2

   Available Since

   June 2, 2014

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

3. pLenti_EF1a_Flag_TP53_WT

   Plasmid

   #183112

   Purpose

   Expresses flag-tagged p53 in mammalian cells

   Depositor

   William Kaelin

   Article

   Stransky et al Proc Natl Acad Sci U S A. 2022 Apr 5;119

   Insert

   TP53 (TP53 Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Mutation

   See Depositor Comments Below

   Promoter

   EF1a

   Available Since

   Aug. 24, 2022

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

4. pCMV5 HA-TBRII (delta Cyt)

   Plasmid

   #14051

   Depositor

   Joan Massague

   Article

   Siegel et al Proc Natl Acad Sci U S A. 2003 Jul 8. 10

   Insert

   TGF beta rec II (delta cyt) (TGFBR2 Human)
   

   Tags

   HA (PYDVPDYA)

   Expression

   Mammalian

   Mutation

   Dominant negative mutant. A stop codon was introd…

   Available Since

   May 10, 2007

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

5. pFRT-TODestFLAGHAhFMRPiso1

   Plasmid

   #48690

   Purpose

   Expresses hFMRP iso 1

   Depositor

   Thomas Tuschl

   Article

   Ascano M et al Nature. 2012 Dec 20;492(7429):382-6. doi

   Insert

   FlagHA FMR1 Iso 1 (FMR1 Human)
   

   Tags

   FLAG and HA

   Expression

   Mammalian

   Promoter

   CMV, 2x Tet

   Available Since

   May 19, 2014

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

6. pcDNA3-ALK5 T204D

   Plasmid

   #80877

   Purpose

   mammalian expression of constitutively active ALK5 T204D

   Depositor

   Aristidis Moustakas

   Article

   Moren et al J Biol Chem. 2005 Jun 10;280(23):22115-2

   Insert

   ALK5 (TGFBR1 Human)
   

   Tags

   HA

   Expression

   Mammalian

   Mutation

   T204D (constitutively active)

   Promoter

   CMV

   Available Since

   Aug. 26, 2016

   Availability

   Academic Institutions and Nonprofits only

7. pCMV5B-HA-Smad2

   Plasmid

   #11734

   Depositor

   Jeff Wrana

   Article

   Eppert et al Cell. 1996 Aug 23. 86(4):543-52.

   Insert

   SMAD2 (SMAD2 Human)
   

   Tags

   HA

   Expression

   Mammalian

   Available Since

   Aug. 3, 2006

   Availability

   Industry, Academic Institutions, and Nonprofits

   

   Enlarge

8. pCX-DI-2A

   Plasmid

   #74671

   Purpose

   Mammalian expression of DI-2A (hCD73/F2A/hCD39)

   Depositor

   Roberto Giovannoni

   Article

   De Giorgi et al Nucleosides Nucleotides Nucleic Acids. 2

   Inserts

   CD73 (NT5E Human)
   CD39 (ENTPD1 Human)
   

   Tags

   F2A

   Expression

   Mammalian

   Promoter

   pCAGGS

   Available Since

   Feb. 14, 2017

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

9. GFP-TREX1(D18N)

   Plasmid

   #27220

   Depositor

   Judy Lieberman

   Article

   Yan et al Nat Immunol. 2010 Nov . 11(11):1005-13.

   Insert

   TREX1 (TREX1 Human)
   

   Tags

   GFP

   Expression

   Mammalian

   Mutation

   D18N sequence 52-GAC changed to AAC, resulting i…

   Available Since

   Jan. 26, 2011

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. pHAGE2 mCherry-Atl1

    Plasmid

    #86678

    Purpose

    Lentivirus to stably express fluorescent protein in mammalian cells

    Depositor

    Tom Rapoport

    Article

    Wang et al Elife. 2016 Sep 13;5. pii: e18605. doi:

    Insert

    ATL1 (ATL1 Human)
    

    Use

    Lentiviral

    Tags

    mCherry

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    Feb. 3, 2017

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

11. pCW57.1-Tet-UPF1WT (pRKB264)

    Plasmid

    #99146

    Purpose

    Inducible lentiviral construct to express FLAG-tagged UPF1wt

    Depositor

    Robert Bradley

    Article

    Feng et al Mol Cell. 2017 Jul 20;67(2):239-251.e6.

    Insert

    UPF1 (UPF1 Human)
    

    Use

    Lentiviral

    Tags

    Flag

    Expression

    Mammalian

    Mutation

    First 127 codons are optimized to reduce GC conte…

    Promoter

    pTight

    Available Since

    Nov. 27, 2017

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

12. pLKO.1-TetON-Puro-HIF1a 3809

    Plasmid

    #118705

    Purpose

    Lentivirus for expression of shRNA1 against human HIF1a (Dox-inducible)

    Depositor

    William Kaelin

    Article

    Briggs et al Cell. 2016 Jun 30;166(1):126-39. doi: 10

    Insert

    shRNA against human HIF1a
    

    Use

    Lentiviral

    Available Since

    Nov. 8, 2018

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

13. pBMN mCherry-OPTN(D474N)

    Plasmid

    #119683

    Purpose

    For mammalian expression of UBD mutant OPTN

    Depositor

    Michael Lazarou

    Article

    Padman et al Nat Commun. 2019 Jan 24;10(1):408. doi:

    Insert

    OPTN (OPTN Human)
    

    Use

    Retroviral

    Tags

    mCherry

    Expression

    Mammalian

    Mutation

    D474N

    Available Since

    Jan. 30, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. pEFIRES-P-EGFP-ADRP

    Plasmid

    #87157

    Purpose

    Fluorescent protein localized to lipid droplets (LDs)

    Depositor

    Elina Ikonen

    Article

    Salo et al EMBO J. 2016 Dec 15;35(24):2699-2716. Ep

    Insert

    ADRP (PLIN2 Human)
    

    Tags

    EGFP

    Expression

    Mammalian

    Promoter

    mCherry-R TTGGTCACCTTCAGCTTGG

    Available Since

    May 30, 2017

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. His-RIAM

    Plasmid

    #32803

    Depositor

    Vicki Boussiotis

    Insert

    RIAM (APBB1IP Human)
    

    Tags

    His and XPress

    Expression

    Mammalian

    Promoter

    T7

    Available Since

    Nov. 18, 2011

    Availability

    Academic Institutions and Nonprofits only

16. pmEGFP-C1-Nir3-LNS2

    Plasmid

    #220087

    Purpose

    C-terminal PA binding domain of Nir3

    Depositor

    Gerry Hammond

    Article

    Weckerly et al J Cell Biol. 2025 Nov 3;224(11):e2024051

    Insert

    PITPNM2 (PITPNM2 Human)
    

    Tags

    mEGFP-GGGGSHM

    Expression

    Mammalian

    Mutation

    amino acids 925-1209

    Promoter

    CMV

    Available Since

    June 13, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. MARS_pNIC-CTB10H

    Plasmid

    #153053

    Purpose

    Expression construct for producing Avi tagged Methionyl-tRNA synthetase

    Depositor

    Susanne Gräslund

    Insert

    MARS (MARS1 Human)
    

    Tags

    TEV-Avi-His10

    Expression

    Bacterial

    Promoter

    T7

    Available Since

    June 29, 2020

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. p7SL-neo-TET

    Plasmid

    #51285

    Purpose

    expresses human 7SL RNA, using its own polIII enhancer, and tagged with the self splicing intron neo cassette

    Depositor

    Astrid Roy-Engel

    Article

    Kroutter et al PLoS Genet. 2009 Apr;5(4):e1000458. doi:

    Insert

    7SL RNA (RN7SL2 Human)
    

    Tags

    neoTET cassette with a tetrahymena self-splicing …

    Expression

    Mammalian

    Promoter

    7SL upstream pollII enhancer

    Available Since

    April 7, 2014

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. LV-hGFAP-SOX2-IRES-GFP

    Plasmid

    #183909

    Purpose

    Expression of human SOX2 and GFP under the human GFAP ABC1D promoter

    Depositor

    Chun-Li Zhang

    Insert

    SOX2 (GFAP, SOX2 Human)
    

    Use

    Lentiviral

    Expression

    Mammalian

    Available Since

    May 19, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. CL20_mEGFP_KMT2A_MLLT1

    Plasmid

    #205842

    Purpose

    Express mEGFP-tagged fusion protein, KMT2A_MLLT1 from patient-derived sequence

    Depositor

    Richard Kriwacki

    Article

    Tripathi et al Nat Commun. 2023 Sep 28;14(1):6008. doi:

    Insert

    KMT2A_MLLT1 (KMT2A, MLLT1 Human)
    

    Tags

    mEGFP

    Expression

    Mammalian

    Available Since

    Nov. 9, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge