We narrowed to 15,910 results for: grna

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pPN066

Plasmid

#91601

Purpose

Express sgRNA targeting human DPP4

Depositor

Lindy Barrett

Publication

Hazelbaker et al Stem Cell Reports. 2017 Oct 10;9(4):1315

Insert

DPP4 (DPP4 Human)

Use

CRISPR

Promoter

U6

Available since

Oct. 12, 2017

Availability

Industry, Academic Institutions, and Nonprofits

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Helios-CRISPR #1 (PX458-EF1a-pSpCas9(BB)-2A-GFP)

Plasmid

#75244

Purpose

CRISPR/Cas9 plasmid against human Helios

Depositor

Ria Baumgrass

Publication

Gabriel et al J Biol Chem. 2016 Sep 16. pii: jbc.M116.

Insert

sgRNA against human Helios (IKZF2 Human)

Use

CRISPR

Available since

June 9, 2016

Availability

Academic Institutions and Nonprofits only

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pAAV-U6-DR30(SapI)-EFS-CasRx-T2A-mCherry-pA

Plasmid

#192481

Purpose

To express CasRX and a gRNA

Depositor

Jonathan Ploski

Publication

Back et al Mol Ther Methods Clin Dev. 2025 Aug 20;3

Insert

CasRx

Use

AAV

Mutation

No

Promoter

U6/EFS

Available since

Aug. 27, 2025

Availability

Academic Institutions and Nonprofits only

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pLenti-sgRELA

Plasmid

#83944

Purpose

Lentiviral vector expressing an sgRNA targeting RELA NOTE: This plasmid does NOT contain Cas9.

Depositor

David Sabatini

Publication

Park et al Nat Genet. 2016 Dec 19. doi: 10.1038/ng.

Insert

sgRELA

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

U6

Available since

Feb. 1, 2021

Availability

Academic Institutions and Nonprofits only

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pKLV-EF1aGFP2AKAT7-linker-mAID-W

Plasmid

#159294

Purpose

Lentiviral vector expressing GFP and KAT7 (gRNA-resistant, mAID-tagged) driven by human EF1a promoter

Depositor

Kosuke Yusa

Publication

Au et al Leukemia. 2021 Apr;35(4):1012-1022. doi:

Insert

KAT7 (KAT7 Human)

Use

Lentiviral

Tags

mAID (auxin-inducible degron)-tagged

Expression

Mammalian

Mutation

CRISPR sites mutated (gRNA ID. 5 and A10)

Promoter

human EF1a promoter

Available since

Oct. 2, 2020

Availability

Academic Institutions and Nonprofits only

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MTK234_033

Plasmid

#123996

Purpose

Encodes the spCas9 sgRNA1 hAAVS1 (site 2) gRNA expression cassette as a type 234 part to be used in the MTK system

Depositor

Hana El-Samad

Publication

Fonseca et al ACS Synth Biol. 2019 Nov 15;8(11):2593-2

Insert

sgRNA2 -hAAVS1

Expression

Mammalian

Available since

Dec. 13, 2019

Availability

Academic Institutions and Nonprofits only

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MTK234_034

Plasmid

#123997

Purpose

Encodes the spCas9 sgRNA1 hAAVS1 (site 3) gRNA expression cassette as a type 234 part to be used in the MTK system

Depositor

Hana El-Samad

Publication

Fonseca et al ACS Synth Biol. 2019 Nov 15;8(11):2593-2

Insert

sgRNA3 -hAAVS1

Expression

Mammalian

Available since

Dec. 13, 2019

Availability

Academic Institutions and Nonprofits only

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MTK0_003

Plasmid

#123925

Purpose

Encodes the spCas9 cassette and spCas9 gRNA GFP dropout expression cassette final destination vector as a type 0 part to be used in the MTK system

Depositor

Hana El-Samad

Publication

Fonseca et al ACS Synth Biol. 2019 Nov 15;8(11):2593-2

Insert

Cas9-sgRNA destination

Expression

Mammalian

Available since

Dec. 13, 2019

Availability

Academic Institutions and Nonprofits only

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FgH1tUTG_huBim_Ex3

Plasmid

#85532

Purpose

Inducible expression of guide RNA (huBim_Ex3) with fluorescent GFP reporter

Depositor

Marco Herold

Publication

Aubrey et al Cell Rep. 2015 Mar 3;10(8):1422-32. doi:

Insert

hu Bim

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

H1t

Available since

Jan. 25, 2017

Availability

Academic Institutions and Nonprofits only

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FgH1tUTG_mup53_Ex4

Plasmid

#85534

Purpose

Inducible expression of guide RNA (mup53_Ex4) with fluorescent GFP reporter

Depositor

Marco Herold

Publication

Aubrey et al Cell Rep. 2015 Mar 3;10(8):1422-32. doi:

Insert

mu p53

Promoter

H1t

Available since

Jan. 25, 2017

Availability

Academic Institutions and Nonprofits only

Cited by

1 Article

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FgH1tUTG_mup53_Ex5

Plasmid

#85535

Purpose

Inducible expression of guide RNA (mup53_Ex5) with fluorescent GFP reporter

Depositor

Marco Herold

Publication

Aubrey et al Cell Rep. 2015 Mar 3;10(8):1422-32. doi:

Insert

mu p53

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

H1t

Available since

Jan. 25, 2017

Availability

Academic Institutions and Nonprofits only

Cited by

1 Article

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pXPR003-sgTP53-5

Plasmid

#118023

Purpose

Constitutive expression of sgRNA targeting human TP53

Depositor

William Hahn, David Root

Publication

Giacomelli et al Nat Genet. 2018 Oct;50(10):1381-1387. do

Insert

sgTP53-5 (TP53 Human)

Use

Lentiviral

Expression

Mammalian

Promoter

hU6

Available since

Oct. 29, 2018

Availability

Academic Institutions and Nonprofits only

Cited by

1 Article

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pLKO Cre-2A-Plgrkt Δ139-147 v4 trcr filler

Plasmid

#256792

Purpose

lentiviral construct with Cre recombinase-2A-Plgrkt Δ139-147 and U6 driven gRNA cassette with the v4 modified trcrRNA. gRNAs can be cloned in by digesting the filler with BsmBI.

Depositor

Daniel Schramek

Publication

Al-Zahrani et al Nature. 2026 Jul 8. doi: 10.1038/s41586-

Insert

Plgrkt (Plgrkt Mouse)

Use

Lentiviral

Mutation

delta139-147

Available since

June 22, 2026

Availability

Academic Institutions and Nonprofits only

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pXPR502 PPH-Cre v14 trcr filler

Plasmid

#256776

Purpose

lentiviral construct with PPH-Cre recombinase (P65-PP7 Coat Protein-HSF1-Cre) U6 driven gRNA cassette with the v14 modified trcrRNA. gRNAs can be cloned in by digesting the filler with SapI.

Depositor

Daniel Schramek

Publication

Al-Zahrani et al Nature. 2026 Jul 8. doi: 10.1038/s41586-

Type

Empty backbone

Use

Lentiviral

Available since

June 22, 2026

Availability

Academic Institutions and Nonprofits only

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pXPR502 PPH-Cre dual trcrs filler

Plasmid

#256778

Purpose

lentiviral construct with PPH-Cre recombinase (P65-PP7 Coat Protein-HSF1-Cre) U6 driven gRNA cassettes with the v4 and v14 modified trcrRNAs. gRNAs can be cloned in with SapI/BsmBI.

Depositor

Daniel Schramek

Publication

Al-Zahrani et al Nature. 2026 Jul 8. doi: 10.1038/s41586-

Type

Empty backbone

Use

Lentiviral

Available since

June 22, 2026

Availability

Academic Institutions and Nonprofits only

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pKb-POC1

Plasmid

#255129

Purpose

Plant expression of rice codon optimized OpenCRISPR1 (OC1). Includes gRNA scaffold.

Depositor

Kutubuddin Molla

Publication

Das et al New Phytol. 2026 May 21. doi: 10.1111/np

Insert

Rice codon optimized pOC1

Expression

Plant

Promoter

Rice ubiquitin promoter for pOC1 and OsU3 promote…

Available since

July 14, 2026

Availability

Academic Institutions and Nonprofits only

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pBK1303-AAV-EFSNC-dCjCas9-MECP2(204-310)

Plasmid

#223148

Purpose

Expression of truncated MECP2 with dCjCas9 and empty gRNA scaffold

Depositor

Boris Kantor

Publication

Kantor et al bioRxiv [Preprint]. 2024 May 19:2023.04.

Insert

MECP2 (MECP2 Human)

Use

AAV and CRISPR

Tags

3xFLAG

Expression

Mammalian

Mutation

Encodes aa 204-310

Promoter

EF1a

Available since

Aug. 28, 2024

Availability

Academic Institutions and Nonprofits only

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pBK1302-AAV-EFSNC-dCjCas9-KRAB

Plasmid

#223147

Purpose

Expression of KRAB with dCjCas9 and empty gRNA scaffold

Depositor

Boris Kantor

Publication

Kantor et al bioRxiv [Preprint]. 2024 May 19:2023.04.

Insert

KRAB

Use

AAV and CRISPR

Tags

3xFLAG

Expression

Mammalian

Promoter

EF1a

Available since

Aug. 23, 2024

Availability

Academic Institutions and Nonprofits only

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pPbHiT_3xmyc_hsp70UTR_hdhfr/yfcu

Plasmid

#216421

Purpose

Empty backbone to express gene specific gRNA and carry the homology repair template for CRISPR editing of Plasmodium berghei using the PbHiT system.

Depositor

Ellen Bushell

Publication

Jonsdottir et al bioRxiv 2024.04.20.590404

Type

Empty backbone

Use

CRISPR; Expression in plasmodium berghei

Tags

3xmyc

Expression

Bacterial

Available since

April 28, 2024

Availability

Academic Institutions and Nonprofits only

Cited by

1 Article

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pPbU6_hdhfr/yfcu

Plasmid

#216422

Purpose

Empty backbone to express gene specific gRNA from the Plasmodium berghei U6 promoter for traditional CRISPR editing.

Depositor

Ellen Bushell

Publication

Jonsdottir et al bioRxiv 2024.04.20.590404

Type

Empty backbone

Use

CRISPR; Expression in plasmodium berghei

Expression

Bacterial

Available since

April 28, 2024

Availability

Academic Institutions and Nonprofits only

Cited by

1 Article

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