We narrowed to 3,367 results for: aaas

1. Lenti-sgWrn#1/Cre

   Plasmid

   #173625

   Purpose

   Expresses a Wrn-targeting gRNA and Cre-recombinase

   Depositor

   Charles Swanton

   Article

   Cai et al Cancer Discov. 2021 Feb 19. pii: 2159-82

   Insert

   gRNA targeting Wrn (Wrn Mouse)
   

   Use

   CRISPR, Cre/Lox, and Lentiviral

   Available Since

   June 7, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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2. Lenti-sgNf1#1/Cre

   Plasmid

   #173607

   Purpose

   Expresses a Nf1-targeting gRNA and Cre-recombinase

   Depositor

   Charles Swanton

   Article

   Cai et al Cancer Discov. 2021 Feb 19. pii: 2159-82

   Insert

   gRNA targeting Nf1 (Nf1 Mouse)
   

   Use

   CRISPR, Cre/Lox, and Lentiviral

   Available Since

   May 17, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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3. eSpCas9(1.1)-ABL1-gRNA2-exon4

   Plasmid

   #163323

   Purpose

   eCas9 ABL1 gRNA 2 (GAAGAAATACAGCCTGACGG), targeting exon 4 within the protein kinase domain of both ABL1 isoforms 1a and 1b.

   Depositor

   Val Brunton

   Article

   Beetham et al Cancer Res. 2021 Dec 17. pii: 0008-5472.

   Insert

   ABL1 gRNA 2_Exon4
   

   Use

   CRISPR

   Expression

   Mammalian

   Promoter

   U6

   Available Since

   Jan. 7, 2022

   Availability

   Academic Institutions and Nonprofits only

4. LentiGuide-Puro-NCOA7g3 (BB24)

   Plasmid

   #139459

   Purpose

   Lentiviral vector with gRNA targeting human NCOA7 short isoform; includes puromycin selectable marker

   Depositor

   Caroline Goujon

   Article

   Doyle et al Nat Microbiol. 2018 Dec;3(12):1369-1376.

   Insert

   NCOA7 short isoform-targeting sgRNA inserted; resistance gene: puroR (NCOA7 Synthetic)
   

   Use

   Lentiviral

   Expression

   Mammalian

   Promoter

   EF-1a / U6

   Available Since

   Oct. 13, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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5. pSECC-sgSIK1-A

   Plasmid

   #138665

   Purpose

   Expresses a mouse SIK1-targeting sgRNA, Cas9, and Cre-recombinase

   Depositor

   Reuben Shaw

   Article

   Hollstein et al Cancer Discov. 2019 Nov;9(11):1606-1627.

   Insert

   sgSIK1 mouse (Sik1 Mouse)
   

   Use

   Lentiviral

   Promoter

   hU6

   Available Since

   March 4, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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6. rd

   Plasmid

   #112912

   Purpose

   Express the PEST domain-replaced 48 kDa form of human dematin with a cleavable N-terminal GST tag

   Depositor

   C. James McKnight

   Article

   Chen et al J Biol Chem. 2013 Mar 22;288(12):8313-20

   Insert

   dematin (DMTN Human)
   

   Tags

   Glutatione-S-Tranferase and precision protease si…

   Expression

   Bacterial

   Mutation

   PEST sequence near the N-terminal removed. 5′-GCG…

   Promoter

   T7

   Available Since

   Aug. 27, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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7. pPN261

   Plasmid

   #91582

   Purpose

   Express sgRNA targeting human CLU

   Depositor

   Lindy Barrett

   Article

   Hazelbaker et al Stem Cell Reports. 2017 Oct 10;9(4):1315

   Insert

   CLU (CLU Human)
   

   Use

   CRISPR

   Promoter

   U6

   Available Since

   Oct. 12, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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8. pLKO.1-shGBP1.2.mKO2

   Plasmid

   #85210

   Purpose

   TRCN0000116120 (Target TGAGACGACGAAAGGCATGTA) for silencing GBP1 gene and express monomeric Kusabira-Orange2.

   Depositor

   Sandra Martha Gomes Dias

   Article

   Quintero et al BMC Cancer. 2017 Nov 7;17(1):727. doi: 1

   Insert

   GBP1 (guanylate binding protein 1) (GBP1 Human)
   

   Use

   Lentiviral and RNAi

   Expression

   Mammalian

   Promoter

   RNA polymerase III promoter for human U6 snRNA fo…

   Available Since

   Oct. 4, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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9. pSIREN-RetroQ-HSPE-sh1

   Plasmid

   #92033

   Purpose

   pSIREN-RetroQ vector containing shRNA sequence to HPSE

   Depositor

   Joe Landry

   Article

   Mayes et al Oncotarget. 2017 May 12;8(38):64344-6435

   Insert

   shRNA #1 to HPSE (Hpse Mouse)
   

   Use

   Retroviral

   Available Since

   July 19, 2017

   Availability

   Industry, Academic Institutions, and Nonprofits

   

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10. pSIREN-RetroQ-HSPE-sh2

    Plasmid

    #92034

    Purpose

    pSIREN-RetroQ vector containing shRNA sequence to HPSE

    Depositor

    Joe Landry

    Article

    Mayes et al Oncotarget. 2017 May 12;8(38):64344-6435

    Insert

    shRNA #2 to HPSE (Hpse Mouse)
    

    Use

    Retroviral

    Available Since

    July 19, 2017

    Availability

    Industry, Academic Institutions, and Nonprofits

    

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11. p426_Cas9_gRNA-SAP155c

    Plasmid

    #87390

    Purpose

    All-in-one CRISPR plasmid for integrating, deleting, or replacing a gene in S. cerevisiae. High-copy, URA3 plasmid contains human codon-optimized Cas9 and a guide RNA targeting SAP155c sequence ATGAAAGACAACTATAGGGC in yeast chromosome 6

    Depositor

    Aindrila Mukhopadhyay

    Article

    Reider Apel et al Nucleic Acids Res. 2017 Jan 9;45(1):496-

    Insert

    Human Optimized S. pyogenes Cas9 and guide RNA targeting SAP155c
    

    Use

    CRISPR

    Promoter

    ADH1, pTyrosine

    Available Since

    April 5, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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12. p426_Cas9_gRNA-RDS1a

    Plasmid

    #87385

    Purpose

    All-in-one CRISPR plasmid for integrating, deleting, or replacing a gene in S. cerevisiae. High-copy, URA3 plasmid contains human codon-optimized Cas9 and a guide RNA targeting RDS1a sequence ATTCAATACGAAATGTGTGC in yeast chromosome 3

    Depositor

    Aindrila Mukhopadhyay

    Article

    Reider Apel et al Nucleic Acids Res. 2017 Jan 9;45(1):496-

    Insert

    Human Optimized S. pyogenes Cas9 and guide RNA targeting RDS1a
    

    Use

    CRISPR

    Promoter

    ADH1, pTyrosine

    Available Since

    April 5, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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13. RIOK1 gRNA (BRDN0001144919)

    Plasmid

    #77657

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human RIOK1

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    RIOK1 (RIOK1 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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14. NUP62 gRNA (BRDN0001148606)

    Plasmid

    #77671

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human NUP62

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    NUP62 (NUP62 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. TPK1 gRNA (BRDN0001146096)

    Plasmid

    #77428

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human TPK1

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    TPK1 (TPK1 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. TPK1 gRNA (BRDN0001148561)

    Plasmid

    #77430

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human TPK1

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    TPK1 (TPK1 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. TWF2 gRNA (BRDN0001148960)

    Plasmid

    #77341

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human TWF2

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    TWF2 (TWF2 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. PLK2 gRNA (BRDN0001148339)

    Plasmid

    #77211

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human PLK2

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    PLK2 (PLK2 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. NME8 gRNA (BRDN0001145469)

    Plasmid

    #77117

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human NME8

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    NME8 (NME8 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. TAF1L gRNA (BRDN0001145686)

    Plasmid

    #77119

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human TAF1L

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    TAF1L (TAF1L Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge