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Tol2_ISCro4_Insertion_Reporter

Plasmid

#251500

Purpose

Reporter plasmid for monitoring insertion activity of ISCro4 bridge recombinase in the presence of native bridge RNA or native TBL and DBL and pDonor_ISCro4_(WT)_Donor_ECFP plasmid

Depositor

Martin Jinek

Article

Pelea et al Science, 2026. eadz1884, doi:10.1126/sci

Insert

ISCro4 insertion reporter

Expression

Mammalian

Mutation

NA

Available Since

Feb. 5, 2026

Availability

Academic Institutions and Nonprofits only

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pDonor_ISCro4_(WT)_Donor_ECFP

Plasmid

#251501

Purpose

Donor plasmid for monitoring insertion activity of ISCro4 bridge recombinase in the presence of native bridge RNA or native TBL and DBL and Tol2_ISCro4_Insertion_Reporter plasmid

Depositor

Martin Jinek

Article

Pelea et al Science, 2026. eadz1884, doi:10.1126/sci

Insert

ISCro4_(WT)_Donor sequence and ECFP

Expression

Mammalian

Mutation

NA

Available Since

Feb. 5, 2026

Availability

Academic Institutions and Nonprofits only

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CMV_3xFLAG_NLS_ISCro4_NLS_SV40_polyA

Plasmid

#251493

Purpose

Expression of a human codon optimised ISCro4 bridge recombinase

Depositor

Martin Jinek

Article

Pelea et al Science, 2026. eadz1884, doi:10.1126/sci

Insert

ISCro4 bridge recombinase

Expression

Mammalian

Mutation

NA

Available Since

Feb. 5, 2026

Availability

Academic Institutions and Nonprofits only

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CMV_3xFLAG_NLS_ISCro4_NLS_T2A_puroR_SV40_polyA

Plasmid

#251494

Purpose

Expression of a human codon optimised ISCro4 bridge recombinase

Depositor

Martin Jinek

Article

Pelea et al Science, 2026. eadz1884, doi:10.1126/sci

Insert

ISCro4 bridge recombinase

Expression

Mammalian

Mutation

NA

Available Since

Feb. 5, 2026

Availability

Academic Institutions and Nonprofits only

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U6_ISCro4_(WT)_full-length_bridge_RNA_polIII_term

Plasmid

#251495

Purpose

Expression of the native full length ISCro4 bridge RNA

Depositor

Martin Jinek

Article

Pelea et al Science, 2026. eadz1884, doi:10.1126/sci

Insert

ISCro4 bridge RNA

Expression

Mammalian

Mutation

NA

Available Since

Feb. 5, 2026

Availability

Academic Institutions and Nonprofits only

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U6_ISCro4_(WT)_TBL_bridge_RNA_polIII_term

Plasmid

#251496

Purpose

Expression of the Target Binding Loop (TBL) component of the native ISCro4 bridge RNA

Depositor

Martin Jinek

Article

Pelea et al Science, 2026. eadz1884, doi:10.1126/sci

Insert

ISCro4 bridge RNA Target Binding Loop (TBL)

Expression

Mammalian

Mutation

NA

Available Since

Feb. 5, 2026

Availability

Academic Institutions and Nonprofits only

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U6_ISCro4_(WT)_DBL_bridge_RNA_polIII_term

Plasmid

#251497

Purpose

Expression of the Donor Binding Loop (DBL) component of the native ISCro4 bridge RNA

Depositor

Martin Jinek

Article

Pelea et al Science, 2026. eadz1884, doi:10.1126/sci

Insert

ISCro4 bridge RNA Donor Binding Loop (DBL)

Expression

Mammalian

Mutation

NA

Available Since

Feb. 5, 2026

Availability

Academic Institutions and Nonprofits only

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pKC152_Lenti_tetoff_PABP-INT_EF1a_EGFP

Plasmid

#250950

Purpose

A lentiviral vector express PABP-INT fusion protein under a Tetoff system. Contains EGFP as selection marker.

Depositor

Fei Chen

Article

Chao et al Science. 2026 Jan 15:eadz9353. doi: 10.1

Insert

PABPC1 (PABPC1 Human)

Use

Lentiviral

Expression

Mammalian

Promoter

TRE3G

Available Since

Jan. 28, 2026

Availability

Academic Institutions and Nonprofits only

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pB-EF1a-CuO-KRAB-dCas9-BFP-CymR-Puro

Plasmid

#248161

Purpose

Expresses KRAB fused to dCas9 and BFP upon cumate induction

Depositor

Joanna Wysocka

Article

Fueyo et al Nature. 2025 Oct 1. doi: 10.1038/s41586-

Inserts

KRAB-dCas9-HA-tagBFP
HA-CymR-T2A-puro

Use

CRISPR

Tags

HA and tagBFP

Expression

Mammalian

Promoter

Ef1a

Available Since

Jan. 27, 2026

Availability

Academic Institutions and Nonprofits only

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pAAV-TRE3G-XRI-FLAG

Plasmid

#250671

Purpose

Timestamp monomer for encoding time along the CytoTape-vivo fiber for mouse brain in vivo applications.

Depositor

Changyang Linghu

Article

Zheng et al Nature. 2026 Jan 26. doi: 10.1038/s41586

Insert

XRI-FLAG

Use

AAV

Expression

Mammalian

Promoter

TRE3G

Available Since

Jan. 12, 2026

Availability

Academic Institutions and Nonprofits only

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pFA6a-mIAA7-ALFA-HIS3MX6

Plasmid

#247627

Purpose

Yeast gene tagging with mIAA7

Depositor

Sebastian Schuck

Article

Hubbe et al Mol Biol Cell. 2026 Feb 1;37(2):mr2. doi

Insert

mIAA7

Tags

ALFA

Expression

Yeast

Available Since

Dec. 12, 2025

Availability

Academic Institutions and Nonprofits only

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pAV-CAG-H2B-mTagBFP2-WPRE-pA

Plasmid

#242711

Purpose

Expression of H2B-mTagBFP2 for nuclei isolation

Depositor

Maria Galazo

Insert

H2B (H2BC11 Human)

Tags

mTagBFP2

Expression

Mammalian

Promoter

CAG

Available Since

Dec. 10, 2025

Availability

Academic Institutions and Nonprofits only

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pAV-CAG-H2B-GFP-WPRE-pA

Plasmid

#242690

Purpose

Expression of H2B-GFP for nuclei isolation

Depositor

Maria Galazo

Insert

H2B (H2BC11 Human)

Tags

sfGFP

Expression

Mammalian

Promoter

CAG

Available Since

Dec. 10, 2025

Availability

Academic Institutions and Nonprofits only

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pFA6a-mIAA7-mNeon-HISMX6

Plasmid

#247607

Purpose

Yeast gene tagging with mIAA7

Depositor

Sebastian Schuck

Article

Hubbe et al Mol Biol Cell. 2026 Feb 1;37(2):mr2. doi

Insert

mIAA7

Tags

mNeonGreen

Expression

Yeast

Available Since

Dec. 9, 2025

Availability

Academic Institutions and Nonprofits only

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R919-X57-566

Plasmid

#244520

Purpose

Bacterial protein expression of His6-MBP-tev-Hs.NRAS(1-169) G12C

Depositor

Dominic Esposito

Insert

His6-MBP-tev-Hs.NRAS(1-169) G12C (NRAS Human)

Tags

His6-MBP

Expression

Bacterial

Available Since

Dec. 2, 2025

Availability

Academic Institutions and Nonprofits only

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pIVT-PuroR-P2A-iCre-polyA_pKG03717

Plasmid

#246369

Purpose

IVT template for making modRNA encoding PuroR-P2A-iCre

Depositor

Kate Galloway

Article

Kabaria et al Nat Biotechnol. 2025 Oct 13. doi: 10.103

Insert

PuroR-P2A-iCre

Use

Synthetic Biology; In vitro transcription

Expression

Mammalian

Mutation

none

Available Since

Nov. 18, 2025

Availability

Academic Institutions and Nonprofits only

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pAAV-hSyn1-DIO-SEP-GluA2

Plasmid

#227233

Purpose

Large cargo capacity AAV that expresses SEP tagged AMPA receptor subunit GluA2 in neurons expressing Cre recombinase

Depositor

Richard Huganir

Article

Hong et al Nature. 2024 Nov;635(8038):398-405. doi:

Insert

SEP-GluA2 (Gria2 Rat)

Use

AAV

Tags

superecliptic pHluorin

Expression

Mammalian

Promoter

hSyn1

Available Since

Oct. 15, 2025

Availability

Academic Institutions and Nonprofits only

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pFdelta6

Plasmid

#232172

Purpose

Expression of Adenoviral Helper Proteins for replication

Depositor

Michael Wehr

Insert

DBP, L3, E3, E4, SPIKE_AD

Use

AAV

Expression

Mammalian

Available Since

Oct. 1, 2025

Availability

Academic Institutions and Nonprofits only

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pBL098

Plasmid

#239091

Purpose

Expresses SXkmer-YLTIRLM under the control of Ptac

Depositor

Tina Wang

Article

Lee et al Nat Chem Biol. 2025 Jul 15. doi: 10.1038

Insert

SXkmer-YLTIRLM

Use

Synthetic Biology

Available Since

Sept. 24, 2025

Availability

Academic Institutions and Nonprofits only

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pBL098ZF

Plasmid

#239090

Purpose

Expresses SXkmer-VKLVCVV under the control of Ptac

Depositor

Tina Wang

Article

Lee et al Nat Chem Biol. 2025 Jul 15. doi: 10.1038

Insert

SXkmer-VKLVCVV

Use

Synthetic Biology

Available Since

Sept. 24, 2025

Availability

Academic Institutions and Nonprofits only

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