We narrowed to 3,367 results for: aaas

1. pMMS22L-siR3

   Plasmid

   #221013

   Purpose

   mammalian expression vector of myc-Flag tagged MMS22L siRNA resistant

   Depositor

   Daniel Durocher

   Article

   O'Donnell et al Mol Cell. 2010 Nov 24;40(4):619-31. doi:

   Insert

   MMS22L (MMS22L Human)
   

   Tags

   Flag and myc

   Expression

   Mammalian

   Mutation

   silent mutations MMS22L: 5'-aaAacGtgTtgCtgTg…

   Promoter

   CMV

   Available Since

   July 31, 2024

   Availability

   Industry, Academic Institutions, and Nonprofits

   

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2. pORANGE Gria2-GFP KI

   Plasmid

   #131490

   Purpose

   Endogenous tagging of GluA2: C-terminal (amino acid position: STOP codon)

   Depositor

   Harold MacGillavry

   Article

   Willems et al PLoS Biol. 2020 Apr 10;18(4):e3000665. d

   Insert

   gRNA and GFP donor (Gria2, Gria2 Mouse, Rat)
   

   Expression

   Mammalian

   Promoter

   U6 and Cbh

   Available Since

   Sept. 25, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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3. pDONR221-SLC1A5_STOP

   Plasmid

   #161140

   Purpose

   Gateway entry clone with codon-optimized ORF sequence for subcloning into custom expression vectors. Contains a STOP codon at the end of the codon-optimized ORF sequence.

   Depositor

   RESOLUTE Consortium, Giulio Superti-Furga

   Article

   Superti-Furga et al Nat Rev Drug Discov. 2020 Jul;19(7):429-

   Insert

   SLC1A5 (SLC1A5 Human)
   

   Expression

   Mammalian

   Available Since

   June 21, 2021

   Availability

   Industry, Academic Institutions, and Nonprofits

   

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4. pXPR003-sgTP53-1

   Plasmid

   #118019

   Purpose

   Constitutive expression of sgRNA targeting human TP53

   Depositor

   William Hahn, David Root

   Article

   Giacomelli et al Nat Genet. 2018 Oct;50(10):1381-1387. do

   Insert

   sgTP53-1 (TP53 Human)
   

   Use

   Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   Oct. 29, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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5. pX335 HTT sgRNA-a

   Plasmid

   #87201

   Purpose

   pX335 vector encoding SpCas9n and a chimeric guide RNA targeting exon 1 of HTT

   Depositor

   Mahmoud Pouladi

   Article

   Xu et al Stem Cell Reports. 2017 Feb 21. pii: S22

   Insert

   HTT (HTT Human)
   

   Use

   CRISPR

   Expression

   Mammalian

   Promoter

   U6

   Available Since

   July 28, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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6. pLKO.puro_shGLS

   Plasmid

   #110335

   Purpose

   shGLS (Target CAACTGGCCAAATTCAGTC), silence human GLS gene, puromycin selection

   Depositor

   Sandra Martha Gomes Dias

   Article

   Dias et al Oncogene. 2020 Jan;39(3):690-702. doi: 1

   Insert

   GLS glutaminase (GLS Synthetic, Human)
   

   Use

   Lentiviral and RNAi

   Expression

   Mammalian

   Promoter

   U6 (RNA PolIII)

   Available Since

   Feb. 23, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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7. pGL3-sgACSL3.C-Cas9-P2A-Puro

   Plasmid

   #129412

   Purpose

   Encoding Cas9 and sgACSL3.C for CRISPR/Cas9 mediated HDR tagging of endogenous human ACSL3 C-terminus

   Depositor

   Elina Ikonen

   Article

   Salo et al Dev Cell. 2019 Jun 6. pii: S1534-5807(19

   Insert

   SpCas9 and sgACSL3.C (ACSL3 Human)
   

   Use

   CRISPR

   Tags

   P2A-Puro

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   Aug. 22, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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8. CSF1R gRNA (BRDN0001146959)

   Plasmid

   #77036

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human CSF1R

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   CSF1R (CSF1R Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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9. pLKO.1-TRC.mKO2_shGLS

   Plasmid

   #110319

   Purpose

   shGLS (Target CAACTGGCCAAATTCAGTC), silence human GLS gene and express monomeric Kusabira-Orange2

   Depositor

   Sandra Martha Gomes Dias

   Article

   Quintero et al BMC Cancer. 2017 Nov 7;17(1):727. doi: 1

   Insert

   GLS Glutaminase (GLS Human)
   

   Use

   Lentiviral and RNAi

   Expression

   Mammalian

   Promoter

   RNA polymerase III promoter for human U6 snRNA fo…

   Available Since

   Nov. 6, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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10. FGFR1 gRNA (BRDN0001146517)

    Plasmid

    #76069

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human FGFR1

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    FGFR1 (FGFR1 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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11. ABL1 gRNA (BRDN0001145259)

    Plasmid

    #77734

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human ABL1

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    ABL1 (ABL1 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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12. IKBKB gRNA (BRDN0001145579)

    Plasmid

    #76090

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human IKBKB

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    IKBKB (IKBKB Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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13. 7AA-aSyn-pRK172

    Plasmid

    #236197

    Purpose

    This plasmid expresses human α-synuclein with a 7-amino acid insertion (MAAAEKT) in the pRK172 backbone for bacterial expression in E. coli. The insertion corresponds to the JOS mutation.

    Depositor

    Yang Yang, Sjors Scheres

    Article

    Yang et al Acta Neuropathol. 2023 May;145(5):561-57

    Insert

    SNCA (SNCA Human)
    

    Expression

    Bacterial

    Mutation

    insertion os MAAAEKT at residue 22

    Available Since

    April 23, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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14. pKLV2-U6gRNA5(BCL11B-E4(44))-PGKpuro2ABFP-W

    Plasmid

    #208560

    Purpose

    Lentiviral vector expressing gRNA targeting human BCL11B-E4

    Depositor

    Kosuke Yusa

    Article

    Aoki et al Blood. 2023 Nov 3:blood.2023020857. doi:

    Insert

    BCL11B-E4(44) (BCL11B Human)
    

    Use

    Lentiviral

    Available Since

    Jan. 18, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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15. pKLV2-U6gRNA5(BCL11B-E4(42))-PGKpuro2ABFP-W

    Plasmid

    #208559

    Purpose

    Lentiviral vector expressing gRNA targeting human BCL11B-E4

    Depositor

    Kosuke Yusa

    Article

    Aoki et al Blood. 2023 Nov 3:blood.2023020857. doi:

    Insert

    BCL11B-E4(42) (BCL11B Human)
    

    Use

    Lentiviral

    Available Since

    Jan. 18, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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16. pKLV2-U6gRNA5(CXCR4-E4(56))-PGKpuro2ABFP-W

    Plasmid

    #200484

    Purpose

    Lentiviral vector expressing gRNA targeting human CXCR4-E4

    Depositor

    Kosuke Yusa

    Article

    Aoki et al Blood. 2023 Nov 3:blood.2023020857. doi:

    Insert

    CXCR4-E4(56) (CXCR4 Human)
    

    Use

    Lentiviral

    Available Since

    Jan. 10, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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17. pKLV2-U6gRNA5(CXCR4-E4(56))-PGKpuro2AmCherry-W

    Plasmid

    #210614

    Purpose

    Lentiviral vector expressing gRNA targeting human CXCR4-E4

    Depositor

    Kosuke Yusa

    Article

    Aoki et al Blood. 2023 Nov 3:blood.2023020857. doi:

    Insert

    CXCR4-E4(56) (CXCR4 Human)
    

    Use

    Lentiviral

    Available Since

    Jan. 8, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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18. MDM4_Deletion_Upstream_gRNA_1

    Plasmid

    #195134

    Purpose

    gRNA in a third generation Cas9 vector with GFP, targeting region immediately upstream of MDM4, to be used with MDM4_Deletion_Downstream_gRNA_1/2 for MDM4 deletion

    Depositor

    Jason Sheltzer

    Article

    Girish et al Science. 2023 Jul 6:eadg4521. doi: 10.11

    Insert

    MDM4 Deletion Upstream gRNA 1 (MDM4 Human)
    

    Expression

    Mammalian

    Available Since

    Feb. 3, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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19. px330-Kmt2c-3

    Plasmid

    #162533

    Purpose

    sgRNA targeting Kmt2c

    Depositor

    Amaia Lujambio

    Article

    Molina-Sanchez et al Gastroenterology. 2020 Aug 16. pii: S001

    Insert

    sgRNA targeting Kmt2c (Kmt2c Mouse)
    

    Expression

    Mammalian

    Mutation

    None

    Promoter

    U6

    Available Since

    Feb. 17, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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20. GK2 gRNA (BRDN0001487045)

    Plasmid

    #77911

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human GK2

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    GK2 (GK2, GALK2 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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