386 results

1. Human Kinase Domain-Focused CRISPR Knockout Library

   Pooled Library

   #117725

   Purpose

   gRNAs targeting the kinase domain of human protein kinases

   Depositor

   Christopher Vakoc

   Article

   Tarumoto et al Mol Cell. 2018 Feb 28. pii: S1097-2765(1

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available Since

   Jan. 4, 2019

   Availability

   Academic Institutions and Nonprofits only

2. TRE-MPRA_minPromega Library

   Pooled Library

   #201013

   Purpose

   Massively parallel reporter assay (MPRA) library with minPromega promoter

   Depositor

   Justin English

   Article

   Zahm et al bioRxiv. 2023 May 11:2023.05.11.539703.

   Expression

   Mammalian

   Use

   Luciferase

   Available Since

   Oct. 31, 2023

   Availability

   Academic Institutions and Nonprofits only

3. Compact mismatched sgRNA library for gene titration (human essential genes, CRISPRi)

   Pooled Library

   #136479

   Purpose

   Expresses gRNAs for gene titration of ~2400 human genes using CRISPRi

   Depositor

   Jonathan Weissman

   Article

   Jost et al Nat Biotechnol. 2020 Jan 13. pii: 10.103

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available Since

   Feb. 25, 2020

   Availability

   Academic Institutions and Nonprofits only

4. Mouse genome-wide lentiviral CRISPR gRNA library version 2

   Pooled Library

   #67988

   Purpose

   Mouse genome-wide CRISPR guide RNA library V2. (pKLV2-U6gRNA5(MouseV2)-PGKpuro2ABFP-W)

   Depositor

   Kosuke Yusa

   Article

   Tzelepis et al Cell Rep. 2016 Oct 18;17(4):1193-1205. d

   Species

   Homo sapiens, Mus musculus, and Synthetic

   Use

   CRISPR and Lentiviral

   Available Since

   Oct. 14, 2016

   Availability

   Academic Institutions and Nonprofits only

5. scQers promoter control #5 (high: EEF1A1 promoter, p028)

   Pooled Library

   #217424

   Purpose

   scQers promoter control #5 (high: EEF1A1 promoter, p028)

   Depositor

   Jay Shendure

   Article

   Lalanne et al bioRxiv 2022.12.10.519236

   Expression

   Bacterial and Mammalian

   Use

   RNAi

   Available Since

   April 3, 2024

   Availability

   Academic Institutions and Nonprofits only

6. SPLINTR GFP v1

   Pooled Library

   #179774

   Purpose

   SPLINTR (Single-cell Profiling and LINeage TRacing) is a high diversity lentiviral barcode library for tracing clonal lineages using bulk and single-cell readouts.

   Depositor

   Mark Dawson

   Article

   Fennell et al Nature. 2022 Jan;601(7891):125-131. doi:

   Expression

   Mammalian

   Use

   Lentiviral

   Available Since

   May 11, 2022

   Availability

   Academic Institutions and Nonprofits only

7. FNLCR CRISPRa Cell Surface

   Pooled Library

   #207471

   Purpose

   CRISPR-based activation library with guide RNAs targeting all cell surface proteins.

   Depositor

   Raj Chari

   Article

   Yang et al Sci Adv. 2024 Feb 16;10(7):eadj2445. doi

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available Since

   Jan. 24, 2024

   Availability

   Academic Institutions and Nonprofits only

8. Liu Lab MusCK (A + B)

   Pooled Library

   #1000000178

   Depositor

   Xiaole Shirley Liu

   Available Since

   Oct. 29, 2021

   Availability

   Academic Institutions and Nonprofits only

9. Bassik lab Mouse CRISPR-Cas9 Deletion Library - Gene Expression

   Pooled Library

   #1000000123

   Purpose

   CRISPR gRNA mouse knockout pooled library - Gene expression

   Depositor

   Michael Bassik

   Available Since

   May 23, 2018

   Availability

   Academic Institutions and Nonprofits only

10. Human sgRNA library Gattinara in pRDA_118 backbone

    Pooled Library

    #136986

    Purpose

    Expresses sgRNAs targeting human genes

    Depositor

    John Doench

    Article

    DeWeirdt et al Nat Commun. 2020 Feb 6;11(1):752. doi: 1

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available Since

    Feb. 24, 2020

    Availability

    Academic Institutions and Nonprofits only