We narrowed to 86 results for: nin

1. SARS-CoV-2 Spike (S) Receptor Binding Domain (RBD) library N501Y Tile 2 (positions 437-527)

   Pooled Library

   #174296

   Purpose

   This library contains mutations to SARS-CoV-2 Spike RBD N501Y variant in which all surface exposed residues on S RBD (Tile 2, positions 437-527) were mutated to every other amino acid.

   Depositor

   Timothy Whitehead

   Article

   Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

   Expression

   Yeast

   Available since

   Sept. 13, 2021

   Availability

   Academic Institutions and Nonprofits only

2. SARS-CoV-2 Spike (S) Receptor Binding Domain (RBD) library N501Y Tile 1 (positions 333-436)

   Pooled Library

   #174295

   Purpose

   This library contains mutations to SARS-CoV-2 Spike RBD N501Y variant in which all surface exposed residues on S RBD (Tile 1, positions 333-436) were mutated to every other amino acid.

   Depositor

   Timothy Whitehead

   Article

   Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

   Expression

   Yeast

   Available since

   Sept. 13, 2021

   Availability

   Academic Institutions and Nonprofits only

3. SARS-CoV-2 Spike (S) Receptor Binding Domain (RBD) library E484K Tile 2 (positions 437-527)

   Pooled Library

   #174294

   Purpose

   This library contains mutations to SARS-CoV-2 Spike RBD E484K variant in which all surface exposed residues on S RBD (Tile 2, positions 437-527) were mutated to every other amino acid.

   Depositor

   Timothy Whitehead

   Article

   Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

   Expression

   Yeast

   Available since

   Sept. 13, 2021

   Availability

   Academic Institutions and Nonprofits only

4. SARS-CoV-2 Spike (S) Receptor Binding Domain (RBD) library E484K Tile 1 (positions 333-436)

   Pooled Library

   #174293

   Purpose

   This library contains mutations to SARS-CoV-2 Spike RBD E484K variant in which all surface exposed residues on S RBD (Tile 1, positions 333-436) were mutated to every other amino acid.

   Depositor

   Timothy Whitehead

   Article

   Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

   Expression

   Yeast

   Available since

   Sept. 13, 2021

   Availability

   Academic Institutions and Nonprofits only

5. pEPIP_PepTile_40merFragments_65CancerDrivers

   Pooled Library

   #172109

   Purpose

   Lentiviral peptide expression library for overexpression fitness screening

   Depositor

   Prashant Mali

   Article

   Ford et al Cell Syst. 2021 Jul 21;12(7):716-732.e7.

   Use

   Lentiviral

   Available since

   Oct. 21, 2021

   Availability

   Academic Institutions and Nonprofits only

6. iSPI_pSer_Subpool#2

   Pooled Library

   #188527

   Purpose

   Express a library of MBP-Fusion proteins containing phosphoserine at a defined position in the fusion protein

   Depositor

   Jesse Rinehart

   Article

   Gassaway et al Nat Methods. 2022 Oct 24. pii: 10.1038/s

   Expression

   Bacterial

   Species

   Homo sapiens

   Available since

   Dec. 14, 2022

   Availability

   Academic Institutions and Nonprofits only

7. iSPI_pSer_Subpool#1

   Pooled Library

   #188526

   Purpose

   Express a library of MBP-Fusion proteins containing phosphoserine at a defined position in the fusion protein

   Depositor

   Jesse Rinehart

   Article

   Gassaway et al Nat Methods. 2022 Oct 24. pii: 10.1038/s

   Expression

   Bacterial

   Species

   Homo sapiens

   Available since

   Dec. 14, 2022

   Availability

   Academic Institutions and Nonprofits only

8. iSPI_pSer_Subpool#3

   Pooled Library

   #188528

   Purpose

   Express a library of MBP-Fusion proteins containing phosphoserine at a defined position in the fusion protein

   Depositor

   Jesse Rinehart

   Article

   Gassaway et al Nat Methods. 2022 Oct 24. pii: 10.1038/s

   Expression

   Bacterial

   Species

   Homo sapiens

   Available since

   Dec. 14, 2022

   Availability

   Academic Institutions and Nonprofits only

9. iSPI_pSer_Subpool#4

   Pooled Library

   #188529

   Purpose

   Express a library of MBP-Fusion proteins containing phosphoserine at a defined position in the fusion protein

   Depositor

   Jesse Rinehart

   Article

   Gassaway et al Nat Methods. 2022 Oct 24. pii: 10.1038/s

   Expression

   Bacterial

   Species

   Homo sapiens

   Available since

   Dec. 14, 2022

   Availability

   Academic Institutions and Nonprofits only

10. iSPI_pSer_Subpool#5

    Pooled Library

    #188530

    Purpose

    Express a library of MBP-Fusion proteins containing phosphoserine at a defined position in the fusion protein

    Depositor

    Jesse Rinehart

    Article

    Gassaway et al Nat Methods. 2022 Oct 24. pii: 10.1038/s

    Expression

    Bacterial

    Species

    Homo sapiens

    Available since

    Dec. 14, 2022

    Availability

    Academic Institutions and Nonprofits only

11. iSPI_pSer_Subpool#6

    Pooled Library

    #188531

    Purpose

    Express a library of MBP-Fusion proteins containing phosphoserine at a defined position in the fusion protein

    Depositor

    Jesse Rinehart

    Article

    Gassaway et al Nat Methods. 2022 Oct 24. pii: 10.1038/s

    Expression

    Bacterial

    Species

    Homo sapiens

    Available since

    Dec. 14, 2022

    Availability

    Academic Institutions and Nonprofits only

12. iSPI_pSer_Subpool#7

    Pooled Library

    #188532

    Purpose

    Express a library of MBP-Fusion proteins containing phosphoserine at a defined position in the fusion protein

    Depositor

    Jesse Rinehart

    Article

    Gassaway et al Nat Methods. 2022 Oct 24. pii: 10.1038/s

    Expression

    Bacterial

    Species

    Homo sapiens

    Available since

    Dec. 14, 2022

    Availability

    Academic Institutions and Nonprofits only

13. iSPI_pSer_Subpool#8

    Pooled Library

    #188533

    Purpose

    Express a library of MBP-Fusion proteins containing phosphoserine at a defined position in the fusion protein

    Depositor

    Jesse Rinehart

    Article

    Gassaway et al Nat Methods. 2022 Oct 24. pii: 10.1038/s

    Expression

    Bacterial

    Species

    Homo sapiens

    Available since

    Dec. 14, 2022

    Availability

    Academic Institutions and Nonprofits only

14. iSPI_pSer_Subpool#9

    Pooled Library

    #188534

    Purpose

    Express a library of MBP-Fusion proteins containing phosphoserine at a defined position in the fusion protein

    Depositor

    Jesse Rinehart

    Article

    Gassaway et al Nat Methods. 2022 Oct 24. pii: 10.1038/s

    Expression

    Bacterial

    Species

    Homo sapiens

    Available since

    Dec. 14, 2022

    Availability

    Academic Institutions and Nonprofits only

15. iSPI_pSer_Subpool#10

    Pooled Library

    #188535

    Purpose

    Express a library of MBP-Fusion proteins containing phosphoserine at a defined position in the fusion protein

    Depositor

    Jesse Rinehart

    Article

    Gassaway et al Nat Methods. 2022 Oct 24. pii: 10.1038/s

    Expression

    Bacterial

    Species

    Homo sapiens

    Available since

    Dec. 14, 2022

    Availability

    Academic Institutions and Nonprofits only

16. iSPI_pSer_Full_library

    Pooled Library

    #188536

    Purpose

    Express a library of MBP-Fusion proteins containing phosphoserine at a defined position in the fusion protein

    Depositor

    Jesse Rinehart

    Article

    Gassaway et al Nat Methods. 2022 Oct 24. pii: 10.1038/s

    Expression

    Bacterial

    Species

    Homo sapiens

    Available since

    Dec. 14, 2022

    Availability

    Academic Institutions and Nonprofits only

17. MORF library without GFP and mCherry controls

    Pooled Library

    #192821

    Purpose

    Barcoded transcription factor ORF library for high throughput screening

    Depositor

    Feng Zhang

    Article

    Joung et al Cell. 2023 Jan 5;186(1):209-229.e26. doi

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    Lentiviral

    Available since

    Jan. 11, 2023

    Availability

    Academic Institutions and Nonprofits only

18. Lenti-human-TF-gRNA-puromycin

    Pooled Library

    #162275

    Purpose

    This is a gRNA library targeting on ~1600 human transcription factors for genetic screening.

    Depositor

    Chunliang Li

    Article

    Zhang et al Elife. 2020 Oct 1;9. pii: 57858. doi: 10

    Species

    Homo sapiens

    Use

    Lentiviral

    Available since

    Dec. 15, 2020

    Availability

    Academic Institutions and Nonprofits only

19. Lourido Toxoplasma CRISPR Library V1

    Pooled Library

    #80636

    Purpose

    Plasmid sgRNA library containing ten guides against each of the 8,158 predicted Toxoplasma gondii protein coding genes.

    Depositor

    Sebastian Lourido

    Article

    Sidik et al Cell. 2016 Sep 8;166(6):1423-1435.e12. d

    Available since

    Sept. 19, 2016

    Availability

    Academic Institutions and Nonprofits only

20. Mouse Brie kinome pooled library, guides 1-4 in lentiCRISPRv2 backbone

    Pooled Library

    #75317

    Purpose

    Mouse sgRNA library in backbone lentiCRISPRv2 targeting 713 kinase genes and containing 2,852 unique sgRNAs along with 100 non-targeting controls

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Available since

    June 27, 2016

    Availability

    Academic Institutions and Nonprofits only

21. Human lentiviral CRISPR library_v1

    Pooled Library

    #69763

    Purpose

    Genome-scale sgRNA screening library in lentiviral vector pLB, targeting 20,121 human protein-coding genes

    Depositor

    Haoquan Wu

    Article

    Ma et al Cell Rep. 2015 Jul 28;12(4):673-83. doi:

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Feb. 9, 2016

    Availability

    Academic Institutions and Nonprofits only

22. KSHV Tiling Library

    Pooled Library

    #180272

    Purpose

    sgRNA library tiling entire ~154 kb of the BAC16 Kaposi’s Sarcoma-associated Herpes viral genome. A guide every ~8 bp allows pooled screening of viral genome.

    Depositor

    Britt Glaunsinger

    Article

    Morgens et al PLoS Pathog. 2022 Jan 18;18(1):e1010236.

    Expression

    Mammalian

    Species

    Kaposi’s sarcoma-associated herpes virus

    Use

    Lentiviral

    Available since

    Feb. 11, 2022

    Availability

    Academic Institutions and Nonprofits only

23. mU6-CR1-CRISPRiv2_hU6-CR3-NT-ctrl-guide_EF1a-PuroR-T2A-BFP

    Pooled Library

    #197348

    Purpose

    To allow for genome-wide genetic modifier screening, the library has a second fixed non-targeting control guide.

    Depositor

    Jonathan Weissman, Rebecca Voorhees

    Article

    Guna et al BMC Genomics. 2023 Oct 30;24(1):651. doi

    Species

    Homo sapiens

    Use

    Lentiviral

    Available since

    May 25, 2023

    Availability

    Academic Institutions and Nonprofits only

24. mU6-CR1-CRISPRiv2_hU6-CR3-EMC2-guide_EF1a-PuroR-T2A-BFP

    Pooled Library

    #197349

    Purpose

    To allow for genome-wide genetic modifier screening, the library has a second fixed guide targeting EMC2.

    Depositor

    Jonathan Weissman, Rebecca Voorhees

    Article

    Guna et al BMC Genomics. 2023 Oct 30;24(1):651. doi

    Species

    Homo sapiens

    Use

    Lentiviral

    Available since

    May 25, 2023

    Availability

    Academic Institutions and Nonprofits only

25. Human sgRNA library Brunello in lentiGuide-Puro

    Pooled Library

    #73178

    Purpose

    Human sgRNA library in backbone lentiGuide-Puro targeting 19,114 genes and containing 76,441 unique sgRNAs along with 1000 non-targeting controls

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Has Service

    Lentiviral Prep

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available since

    Feb. 9, 2016

    Availability

    Academic Institutions and Nonprofits only

26. Human sgRNA library Brunello in lentiCRISPRv2

    Pooled Library

    #73179

    Purpose

    Human sgRNA library in backbone lentiCRISPRv2 targeting 19,114 genes and containing 76,441 unique sgRNAs along with 1000 non-targeting controls

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Has Service

    Lentiviral Prep

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available since

    Feb. 9, 2016

    Availability

    Academic Institutions and Nonprofits only

27. Mouse sgRNA library Brie in lentiCRISPRv2

    Pooled Library

    #73632

    Purpose

    Mouse sgRNA library in backbone lentiCRISPRv2 containing 78,637 unique sgRNAs targeting 19,674 genes along with 1000 non-targeting controls

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available since

    Feb. 25, 2016

    Availability

    Academic Institutions and Nonprofits only

28. Mouse Brie kinome pooled library, guides 1-4 in lentiGuide-Puro backbone

    Pooled Library

    #75316

    Purpose

    Mouse sgRNA library in backbone lentiGuide-Puro targeting 713 kinase genes and containing 2,852 unique sgRNAs along with 100 non-targeting controls

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Available since

    June 27, 2016

    Availability

    Academic Institutions and Nonprofits only

29. Mouse sgRNA library Brie in lentiGuide-Puro

    Pooled Library

    #73633

    Purpose

    Mouse sgRNA library in backbone lentiGuide-Puro containing 78,637 unique sgRNAs targeting 19,674 genes along with 1000 non-targeting controls

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Has Service

    Lentiviral Prep

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available since

    Feb. 25, 2016

    Availability

    Academic Institutions and Nonprofits only

30. Human Brunello kinome pooled library, guides 1-4 in lentiCRISPRv2 backbone

    Pooled Library

    #75314

    Purpose

    Human sgRNA library in backbone lentiCRISPRv2 targeting 763 kinase genes and containing 3,052 unique sgRNAs along with 100 non-targeting controls

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available since

    June 27, 2016

    Availability

    Academic Institutions and Nonprofits only

31. Human Brunello kinome pooled library, guides 1-4 in lentiGuide-Puro backbone

    Pooled Library

    #75312

    Purpose

    Human sgRNA library in backbone lentiGuide-Puro targeting 763 kinase genes and containing 3,052 unique sgRNAs along with 100 non-targeting controls

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available since

    June 27, 2016

    Availability

    Academic Institutions and Nonprofits only

32. Human Brunello kinome pooled library, guides 5-8 in lentiCRISPRv2 backbone

    Pooled Library

    #75315

    Purpose

    Human sgRNA library in backbone lentiCRISPRv2 targeting 763 kinase genes and containing 3,052 unique sgRNAs along with 100 non-targeting controls

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available since

    June 27, 2016

    Availability

    Academic Institutions and Nonprofits only

33. Human Brunello kinome pooled library, guides 5-8 in lentiGuide-Puro backbone

    Pooled Library

    #75313

    Purpose

    Human sgRNA library in backbone lentiGuide-Puro targeting 763 kinase genes and containing 3,052 unique sgRNAs along with 100 non-targeting controls

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available since

    June 27, 2016

    Availability

    Academic Institutions and Nonprofits only

34. TP53 MITE Library

    Pooled Library

    #113569

    Purpose

    Pooled lentiviral plasmid library containing ~8,000 single amino acid substitution and nonsense mutant variants of p53

    Depositor

    David Root, William Hahn

    Article

    Giacomelli et al Nat Genet. 2018 Oct;50(10):1381-1387. do

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    Lentiviral

    Available since

    Jan. 4, 2019

    Availability

    Academic Institutions and Nonprofits only

35. CHyMErA Large-Scale Exon Deletion hgRNA Library

    Pooled Library

    #209736

    Purpose

    CHyMErA Exon Deletion hgRNA Library allows identification of frame-preserving exons that affect cell fitness in human cells using the CHyMErA screening platform.

    Depositor

    Thomas Gonatopoulos-Pournatzis

    Article

    Xiao et al Mol Cell. 2024 Jul 11;84(13):2553-2572.e

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available since

    June 20, 2024

    Availability

    Academic Institutions and Nonprofits only

36. Green monkey (Chlorocebus sabaeus) sgRNA library

    Pooled Library

    #178284

    Purpose

    Genome-wide CRISPR screening library targeting 20,991 genes in C. sabaeus, 84,963 total gRNAs

    Depositor

    John Doench, David Root

    Article

    Wei et al Cell. 2021 Jan 7;184(1):76-91.e13. doi:

    Expression

    Mammalian

    Species

    Chlorocebus sabaeus (african green monkey)

    Use

    CRISPR and Lentiviral

    Available since

    Nov. 23, 2021

    Availability

    Academic Institutions and Nonprofits only