We narrowed to 43 results for: tes

1. CRISPRi non-coding library (CRiNCL) - K562 & HeLa

   Pooled Library

   #86549

   Depositor

   Jonathan Weissman

   Article

   Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

   Available since

   March 8, 2017

   Availability

   Academic Institutions and Nonprofits only

2. CRISPRi non-coding library (CRiNCL) - K562, HeLa, & MCF7

   Pooled Library

   #86548

   Depositor

   Jonathan Weissman

   Article

   Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

   Available since

   March 8, 2017

   Availability

   Academic Institutions and Nonprofits only

3. CRISPRi non-coding library (CRiNCL) - Unique to HeLa

   Pooled Library

   #86545

   Depositor

   Jonathan Weissman

   Article

   Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

   Available since

   March 8, 2017

   Availability

   Academic Institutions and Nonprofits only

4. Mouse lipid metabolism knockout library

   Pooled Library

   #206248

   Purpose

   The lipid metabolism library contains guide RNAs against 295 genes targeting mouse genes encoding enzymes that directly impact lipid metabolism.

   Depositor

   Kivanc Birsoy

   Article

   Soula et al Nature. 2024 Aug 7. doi: 10.1038/s41586-

   Use

   CRISPR and Lentiviral

   Available since

   Aug. 29, 2024

   Availability

   Academic Institutions and Nonprofits only

5. ACER

   Pooled Library

   #226117

   Purpose

   The Advanced Catalogue of Epigenetic Regulators (ACER) library allows scientists to study how different epigenetic proteins influence gene activity and contribute to diseases.

   Depositor

   Rui Lu

   Article

   Zhou et al Blood. 2024 Aug 16:blood.2023023644. doi

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   Oct. 29, 2024

   Availability

   Academic Institutions and Nonprofits only

6. Bison sgRNA library

   Pooled Library

   #169942

   Purpose

   The BISON CRISPR library targets 713 E1, E2, and E3 ubiquitin ligases, deubiquitinases, and control genes and contains 2,852 guide RNAs. It was cloned into the pXPR003.

   Depositor

   Benjamin Ebert

   Article

   Slabicki et al Nature. 2020 Sep;585(7824):293-297. doi:

   Use

   Lentiviral

   Available since

   Sept. 9, 2021

   Availability

   Academic Institutions and Nonprofits only

7. Mouse Chromatin Regulator Library

   Pooled Library

   #200011

   Purpose

   CRISPR KO library targeting a comprehensive set of genes with annotated function as chromatin regulators.

   Depositor

   Gabriel Griffin, Robert Manguso, Bradley Bernstein

   Article

   Griffin et al Nature. 2021 Jul;595(7866):309-314. doi:

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   Dec. 15, 2023

   Availability

   Academic Institutions and Nonprofits only

8. Human Transporter Knockout library

   Pooled Library

   #213695

   Purpose

   Next generation transporter-focused CRISPR/Cas9 library targeting transmembrane transporters to test the impact of transporters on biological processes.

   Depositor

   RESOLUTE Consortium, Giulio Superti-Furga

   Article

   Ferdigg et al Life Sci Alliance. 2024 Nov 22;8(2):e202

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   Sept. 13, 2024

   Availability

   Academic Institutions and Nonprofits only

9. Human Transporter Knockout Library with UMIs

   Pooled Library

   #221409

   Purpose

   gRNA library to test the impact of transporters on biological processes

   Depositor

   RESOLUTE Consortium, Giulio Superti-Furga

   Article

   Wolf et al Cell Chem Biol. 2024 Dec 24:S2451-9456(2

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   Sept. 13, 2024

   Availability

   Academic Institutions and Nonprofits only

10. lentiGuide-Puro-pKO-library

    Pooled Library

    #190744

    Purpose

    CRISPR/Cas9 paired-guide RNA library to delete proximal poly(A) sites in mouse melanoma.

    Depositor

    Robert Bradley

    Article

    Gabel et al Nat Commun. 2024 Feb 1;15(1):959. doi: 1

    Expression

    Mammalian

    Species

    Mus musculus

    Use

    CRISPR, Lentiviral, and Mouse Targeting

    Available since

    Feb. 2, 2024

    Availability

    Academic Institutions and Nonprofits only

11. Mouse Cardiac Transcriptional Regulators CRISPR Knockout Library

    Pooled Library

    #138015

    Purpose

    This library can be used to investigate cardiac gene regulation. It targets transcriptional regulators that are expressed in mouse cardiomyocytes. A subset of GATA4 regulated genes are also included.

    Depositor

    William Pu

    Article

    VanDusen et al bioRxiv 2019, 808402v1; doi: https://doi

    Species

    Mus musculus

    Use

    AAV, CRISPR, and Cre/Lox

    Available since

    April 17, 2020

    Availability

    Academic Institutions and Nonprofits only

12. Human SLC overexpression library

    Pooled Library

    #213694

    Purpose

    Inducible barcoded library with 467 codon-optimized cDNAs with UMIs to test the impact of SLC transporters on biological processes.

    Depositor

    RESOLUTE Consortium, Giulio Superti-Furga

    Article

    Wolf et al Cell Chem Biol. 2024 Dec 24:S2451-9456(2

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    Lentiviral

    Available since

    Aug. 30, 2024

    Availability

    Academic Institutions and Nonprofits only

13. Human CRISPR Poison Exon Knockout Library

    Pooled Library

    #138084

    Purpose

    The human pgPoison library induces skipping of “poison” cassette exons and corresponding upstream constitutive exons by targeting 3' splice sites with paired gRNAs (pgRNAs).

    Depositor

    Robert Bradley

    Article

    Thomas et al Nat Genet. 2020 Jan;52(1):84-94. doi: 10

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    March 6, 2020

    Availability

    Academic Institutions and Nonprofits only

14. Human ABC Transporter Knockout Sub-library with UMIs

    Pooled Library

    #221410

    Purpose

    gRNA library to test the impact of transporters on biological processes (subset: ABC transporters and controls)

    Depositor

    RESOLUTE Consortium, Giulio Superti-Furga

    Article

    Wolf et al Cell Chem Biol. 2024 Dec 24:S2451-9456(2

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Sept. 13, 2024

    Availability

    Academic Institutions and Nonprofits only

15. MYC-CRISPR

    Pooled Library

    #173195

    Purpose

    This pooled lentiviral CRISPR knockout library targets E-boxes genome-wide and can be applied for identification of essential MYC binding sites in a wide range of human cells.

    Depositor

    Agnieszka Dzikiewicz-Krawczyk

    Article

    Kazimierska et al Mol Oncol. 2023 Nov;17(11):2295-2313. do

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Aug. 11, 2021

    Availability

    Academic Institutions and Nonprofits only

16. plIG-123_HA-GD2-28z_CAR_TF_Library

    Pooled Library

    #207478

    Purpose

    HA-GD2-28z CAR in combination with 100 transcription factors (and related proteins) and 2 controls (GFP/RFP). Library can be used to generate HDR templates for modular pooled knockin (ModPoKI) into th

    Depositor

    Alexander Marson

    Article

    Blaeschke et al Cell. 2023 Sep 14;186(19):4216-4234.e33.

    Species

    Homo sapiens

    Use

    CRISPR

    Available since

    Jan. 26, 2024

    Availability

    Academic Institutions and Nonprofits only

17. plIG-128_HA-GD2-28z_CAR_TFxTF_Library

    Pooled Library

    #207480

    Purpose

    HA-GD2-28z CAR in combination with ~10,000 transcription factor combinations (and related proteins) and controls (GFP/RFP combinations). Library can be used to generate HDR templates for modular poole

    Depositor

    Alexander Marson

    Article

    Blaeschke et al Cell. 2023 Sep 14;186(19):4216-4234.e33.

    Use

    CRISPR

    Available since

    Jan. 26, 2024

    Availability

    Academic Institutions and Nonprofits only

18. plIG-106_NY-ESO-1_TCR_SR_Library

    Pooled Library

    #207474

    Purpose

    NY-ESO-1 TCR in combination with 129 surface receptors and 2 controls (GFP/RFP). Library can be used to generate HDR templates for modular pooled knockin (ModPoKI) into the TRAC locus of human T cells

    Depositor

    Alexander Marson

    Article

    Blaeschke et al Cell. 2023 Sep 14;186(19):4216-4234.e33.

    Species

    Homo sapiens

    Use

    CRISPR

    Available since

    Jan. 26, 2024

    Availability

    Academic Institutions and Nonprofits only

19. plIG-107_NY-ESO-1_TCR_TF_Library

    Pooled Library

    #207475

    Purpose

    NY-ESO-1 TCR in combination with 100 transcription factors (and related proteins) and 2 controls (GFP/RFP). Library can be used to generate HDR templates for modular pooled knockin (ModPoKI) into the

    Depositor

    Alexander Marson

    Article

    Blaeschke et al Cell. 2023 Sep 14;186(19):4216-4234.e33.

    Species

    Homo sapiens

    Use

    CRISPR

    Available since

    Jan. 26, 2024

    Availability

    Academic Institutions and Nonprofits only

20. plIG-109_CD19-BBz_CAR_SR_Library

    Pooled Library

    #207476

    Purpose

    CD19-BBz CAR in combination with 129 surface receptors and 2 controls (GFP/RFP). Library can be used to generate HDR templates for modular pooled knockin (ModPoKI) into the TRAC locus of human T cells

    Depositor

    Alexander Marson

    Article

    Blaeschke et al Cell. 2023 Sep 14;186(19):4216-4234.e33.

    Use

    CRISPR

    Available since

    Jan. 26, 2024

    Availability

    Academic Institutions and Nonprofits only