We narrowed to 83 results for: SAP

1. FNLCR CRISPRa Cell Surface

   Pooled Library

   #207471

   Purpose

   CRISPR-based activation library with guide RNAs targeting all cell surface proteins.

   Depositor

   Raj Chari

   Article

   Yang et al Sci Adv. 2024 Feb 16;10(7):eadj2445. doi

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   Jan. 24, 2024

   Availability

   Academic Institutions and Nonprofits only

2. DNA repair library with 1,573 sgRNAs

   Pooled Library

   #177663

   Purpose

   CRISPR-interference (CRISPRi) library of 1,573 sgRNAs targeting 476 genes encoding factors involved in DNA repair and associated processes

   Depositor

   Brittany Adamson

   Article

   Hussmann et al Cell. 2021 Oct 28;184(22):5653-5669.e25.

   Species

   Homo sapiens

   Use

   CRISPR

   Available since

   July 11, 2023

   Availability

   Academic Institutions and Nonprofits only

3. Lenti-human-UBDUB-gRNA-puromycin-IRES-CFP

   Pooled Library

   #171531

   Purpose

   Pooled gRNA library against human ubiquitination and de-ubiquitination complex genes (UBDUB)

   Depositor

   Chunliang Li

   Article

   Wright et al Proc Natl Acad Sci U S A. 2023 Apr 18;12

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   Lentiviral

   Available since

   June 22, 2021

   Availability

   Academic Institutions and Nonprofits only

4. Human Metabolic Gene CRISPRa sgRNA library

   Pooled Library

   #187080

   Purpose

   Lentiviral CRISPRa library targeting human metabolic genes for activation of gene expression

   Depositor

   Kivanc Birsoy

   Article

   Unlu et al Mol Cell. 2022 Aug 4;82(15):2832-2843.e7

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   Lentiviral

   Available since

   Oct. 26, 2022

   Availability

   Academic Institutions and Nonprofits only

5. Human lentiviral CRISPR library_v1

   Pooled Library

   #69763

   Purpose

   Genome-scale sgRNA screening library in lentiviral vector pLB, targeting 20,121 human protein-coding genes

   Depositor

   Haoquan Wu

   Article

   Ma et al Cell Rep. 2015 Jul 28;12(4):673-83. doi:

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   Feb. 9, 2016

   Availability

   Academic Institutions and Nonprofits only

6. Pan-Druggable Cancer Library

   Pooled Library

   #182133

   Purpose

   All-in-one CRISPR/Cas system with 74 individual elements. 63 elements target cancer-related genes with FDA-approved drug treatments, and 3 elements target key medulloblastoma driver genes.

   Depositor

   Prashant Mali

   Article

   Hu et al Biomaterials. 2022 Jan;280:121276. doi:

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   Aug. 26, 2022

   Availability

   Academic Institutions and Nonprofits only

7. BARBEKO sgRNA library

   Pooled Library

   #174163

   Purpose

   iBARed cytosine Base Editing-mediated gene KnockOut (BARBEKO) sgRNA library; This library leverages CRISPR cytosine base editors for genome-scale knockout screens.

   Depositor

   Wensheng Wei

   Article

   Xu et al Nat Biotechnol. 2021 Jun 21. pii: 10.103

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   Aug. 31, 2021

   Availability

   Academic Institutions and Nonprofits only

8. Human Transporter Knockout Library with UMIs

   Pooled Library

   #221409

   Purpose

   gRNA library to test the impact of transporters on biological processes

   Depositor

   Giulio Superti-Furga, RESOLUTE Consortium

   Article

   Wolf et al Cell Chem Biol. 2024 Dec 24:S2451-9456(2

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   Sept. 13, 2024

   Availability

   Academic Institutions and Nonprofits only

9. mTORC1 Focused library

   Pooled Library

   #164084

   Purpose

   Lentiviral CRISPR library targets human mTORC1 signaling pathway

   Depositor

   David Sabatini

   Article

   Condon et al Proc Natl Acad Sci U S A. 2021 Jan 26;11

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   Jan. 11, 2021

   Availability

   Academic Institutions and Nonprofits only

10. DNA repair library with 336 sgRNAs

    Pooled Library

    #177664

    Purpose

    CRISPR-interference (CRISPRi) library of 366 sgRNAs targeting 118 genes encoding factors involved in DNA repair and associated processes

    Depositor

    Brittany Adamson

    Article

    Hussmann et al Cell. 2021 Oct 28;184(22):5653-5669.e25.

    Species

    Homo sapiens

    Use

    CRISPR

    Available since

    Nov. 29, 2023

    Availability

    Academic Institutions and Nonprofits only

11. mU6-CR1-CRISPRiv2_hU6-CR3-NT-ctrl-guide_EF1a-PuroR-T2A-BFP

    Pooled Library

    #197348

    Purpose

    To allow for genome-wide genetic modifier screening, the library has a second fixed non-targeting control guide.

    Depositor

    Rebecca Voorhees, Jonathan Weissman

    Article

    Guna et al BMC Genomics. 2023 Oct 30;24(1):651. doi

    Species

    Homo sapiens

    Use

    Lentiviral

    Available since

    May 25, 2023

    Availability

    Academic Institutions and Nonprofits only

12. mU6-CR1-CRISPRiv2_hU6-CR3-EMC2-guide_EF1a-PuroR-T2A-BFP

    Pooled Library

    #197349

    Purpose

    To allow for genome-wide genetic modifier screening, the library has a second fixed guide targeting EMC2.

    Depositor

    Rebecca Voorhees, Jonathan Weissman

    Article

    Guna et al BMC Genomics. 2023 Oct 30;24(1):651. doi

    Species

    Homo sapiens

    Use

    Lentiviral

    Available since

    May 25, 2023

    Availability

    Academic Institutions and Nonprofits only

13. MinLibCas9

    Pooled Library

    #164896

    Purpose

    Human genome-wide CRISPR-Cas9 gRNA library, optimised by mining existing large-scale screening datasets, which provides a >60% reduction in size while preserving key information content

    Depositor

    Mathew Garnett

    Article

    Gonçalves et al Genome Biol. 2021 Jan 21;22(1):40. doi:

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    May 20, 2021

    Availability

    Academic Institutions and Nonprofits only

14. Human Epigenetic Knockout Library

    Pooled Library

    #162256

    Purpose

    Lentiviral CRISPR library targets human epigenetic genes

    Depositor

    Kivanc Birsoy

    Article

    Williams et al Cell Metab. 2020 Apr 7;31(4):852-861.e6.

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Nov. 17, 2020

    Availability

    Academic Institutions and Nonprofits only

15. Human SLC overexpression library

    Pooled Library

    #213694

    Purpose

    Inducible barcoded library with 467 codon-optimized cDNAs with UMIs to test the impact of SLC transporters on biological processes.

    Depositor

    Giulio Superti-Furga, RESOLUTE Consortium

    Article

    Wolf et al Cell Chem Biol. 2024 Dec 24:S2451-9456(2

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    Lentiviral

    Available since

    Aug. 30, 2024

    Availability

    Academic Institutions and Nonprofits only

16. ACER

    Pooled Library

    #226117

    Purpose

    The Advanced Catalogue of Epigenetic Regulators (ACER) library allows scientists to study how different epigenetic proteins influence gene activity and contribute to diseases.

    Depositor

    Rui Lu

    Article

    Zhou et al Blood. 2024 Aug 16:blood.2023023644. doi

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Oct. 29, 2024

    Availability

    Academic Institutions and Nonprofits only

17. Human DNA Binding Domain-Focused CRISPR Knockout Library

    Pooled Library

    #123334

    Purpose

    Expresses gRNA targeting the DNA binding domain of human transcription factors.

    Depositor

    Christopher Vakoc

    Article

    Huang et al Genes Dev. 2018 Jul 1;32(13-14):915-928.

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    May 2, 2019

    Availability

    Academic Institutions and Nonprofits only

18. Human SLC SAM Library

    Pooled Library

    #132561

    Purpose

    Expresses gRNAs for activation of human Solute Carrier family genes

    Depositor

    Giulio Superti-Furga

    Article

    Rebsamen et al Life Sci Alliance. 2022 Sep 16;5(11):e20

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    May 18, 2020

    Availability

    Academic Institutions and Nonprofits only

19. Splicing-targeting CRISPR-Cas9 library for human lncRNAs

    Pooled Library

    #119977

    Purpose

    The CRISPR sgRNA library was designed to target the 5' or 3' splice sites of lncRNAs in genome-scale, in order to knockout the targeted lncRNAs.

    Depositor

    Wensheng Wei

    Article

    Liu et al Nat Biotechnol. 2018 Nov 5. pii: nbt.428

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    March 27, 2019

    Availability

    Academic Institutions and Nonprofits only

20. Human CRISPR Poison Exon Knockout Library

    Pooled Library

    #138084

    Purpose

    The human pgPoison library induces skipping of “poison” cassette exons and corresponding upstream constitutive exons by targeting 3' splice sites with paired gRNAs (pgRNAs).

    Depositor

    Robert Bradley

    Article

    Thomas et al Nat Genet. 2020 Jan;52(1):84-94. doi: 10

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    March 6, 2020

    Availability

    Academic Institutions and Nonprofits only