We narrowed to 151 results for: LAS

1. PBbtCRISPRko.v1

   Pooled Library

   #213928

   Purpose

   Uses the PiggyBac transposon system to deliver the library into hard to transduce cells

   Depositor

   Wenfang Spring Tan

   Article

   Tan et al PLoS Pathog. 2023 Dec 6;19(12):e1011822.

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   April 9, 2024

   Availability

   Academic Institutions and Nonprofits only

2. Human Genome-Wide Reduced Double-gRNA library

   Pooled Library

   #137999

   Purpose

   This gRNA library targets the human coding genome, aimed to reduce the scale of genome-wide perturbation screens up to fivefold compared to conventional methods, without sacrificing performance.

   Depositor

   Leopold Parts

   Article

   Peets et al bioRxiv 859652

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   Oct. 15, 2020

   Availability

   Academic Institutions and Nonprofits only

3. Human Transporter Knockout library

   Pooled Library

   #213695

   Purpose

   Next generation transporter-focused CRISPR/Cas9 library targeting transmembrane transporters to test the impact of transporters on biological processes.

   Depositor

   Giulio Superti-Furga, RESOLUTE Consortium

   Article

   Ferdigg et al Life Sci Alliance. 2024 Nov 22;8(2):e202

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   Sept. 13, 2024

   Availability

   Academic Institutions and Nonprofits only

4. Pdest-EF1α-EGFP-32bp barcode polyA library

   Pooled Library

   #211610

   Purpose

   Barcoded retrovirus plasmid library for capturing the transcriptome and viral barcode sequences of individual cells to infer their identities and lineage information.

   Depositor

   Yuejun Chen

   Article

   You et al Cell Stem Cell. 2023 Apr 6;30(4):473-487

   Species

   Synthetic

   Use

   Retroviral

   Available since

   Aug. 29, 2024

   Availability

   Academic Institutions and Nonprofits only

5. Human Paralog Knockout Library (pgPEN)

   Pooled Library

   #171172

   Purpose

   CRISPR library targets human duplicate paralog gene pairs

   Depositor

   Alice Berger

   Article

   Parrish et al Cell Rep. 2021 Aug 31;36(9):109597. doi:

   Expression

   Mammalian

   Species

   Homo sapiens and Synthetic

   Use

   CRISPR and Lentiviral

   Available since

   Sept. 28, 2021

   Availability

   Academic Institutions and Nonprofits only

6. RNA-binding protein pooled CRISPR knockout library

   Pooled Library

   #141438

   Purpose

   CRISPR knockout library targets RBPs with 10 sgRNAs/gene

   Depositor

   Eugene Yeo

   Article

   Wheeler et al Nat Methods. 2020 May 11. pii: 10.1038/s

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   May 28, 2020

   Availability

   Academic Institutions and Nonprofits only

7. Watermelon

   Pooled Library

   #155257

   Purpose

   Lineage tracing library

   Depositor

   Joan Brugge, Aviv Regev

   Article

   Oren et al Nature. 2021 Aug 11. pii: 10.1038/s41586

   Expression

   Mammalian

   Use

   Lentiviral

   Available since

   Oct. 15, 2021

   Availability

   Academic Institutions and Nonprofits only

8. Mouse metabolism knockout library

   Pooled Library

   #160129

   Purpose

   CRISPR library targets mouse metabolic genes

   Depositor

   Kivanc Birsoy

   Article

   Zhu et al Cell Metab. 2020 Oct 28. pii: S1550-4131

   Expression

   Mammalian

   Species

   Mus musculus

   Use

   CRISPR and Lentiviral

   Available since

   Nov. 10, 2020

   Availability

   Academic Institutions and Nonprofits only

9. BARBEKO sgRNA library

   Pooled Library

   #174163

   Purpose

   iBARed cytosine Base Editing-mediated gene KnockOut (BARBEKO) sgRNA library; This library leverages CRISPR cytosine base editors for genome-scale knockout screens.

   Depositor

   Wensheng Wei

   Article

   Xu et al Nat Biotechnol. 2021 Jun 21. pii: 10.103

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   Aug. 31, 2021

   Availability

   Academic Institutions and Nonprofits only

10. Human Metabolic Gene CRISPRa sgRNA library

    Pooled Library

    #187080

    Purpose

    Lentiviral CRISPRa library targeting human metabolic genes for activation of gene expression

    Depositor

    Kivanc Birsoy

    Article

    Unlu et al Mol Cell. 2022 Aug 4;82(15):2832-2843.e7

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    Lentiviral

    Available since

    Oct. 26, 2022

    Availability

    Academic Institutions and Nonprofits only

11. Mouse Metabolic Gene CRISPRa sgRNA library

    Pooled Library

    #187081

    Purpose

    Lentiviral CRISPRa library targeting mouse metabolic genes for activation of gene expression

    Depositor

    Kivanc Birsoy

    Article

    Unlu et al Mol Cell. 2022 Aug 4;82(15):2832-2843.e7

    Expression

    Mammalian

    Species

    Mus musculus

    Use

    Lentiviral

    Available since

    Oct. 26, 2022

    Availability

    Academic Institutions and Nonprofits only

12. Human lentiviral CRISPR library_v1

    Pooled Library

    #69763

    Purpose

    Genome-scale sgRNA screening library in lentiviral vector pLB, targeting 20,121 human protein-coding genes

    Depositor

    Haoquan Wu

    Article

    Ma et al Cell Rep. 2015 Jul 28;12(4):673-83. doi:

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Feb. 9, 2016

    Availability

    Academic Institutions and Nonprofits only

13. Pan-Druggable Cancer Library

    Pooled Library

    #182133

    Purpose

    All-in-one CRISPR/Cas system with 74 individual elements. 63 elements target cancer-related genes with FDA-approved drug treatments, and 3 elements target key medulloblastoma driver genes.

    Depositor

    Prashant Mali

    Article

    Hu et al Biomaterials. 2022 Jan;280:121276. doi:

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Aug. 26, 2022

    Availability

    Academic Institutions and Nonprofits only

14. Pooled sgRNA Libraries Set 1 for Pseudomonas aeruginosa PA14

    Pooled Library

    #234855

    Purpose

    A CRISPRi library for inducible, genome-wide gene repression in Pseudomonas aeruginosa PA14.

    Depositor

    Xue Liu

    Article

    Zhang et al Nat Commun. 2025 Jul 1;16(1):5870. doi:

    Expression

    Bacterial

    Available since

    June 5, 2025

    Availability

    Academic Institutions and Nonprofits only

15. MinLibCas9

    Pooled Library

    #164896

    Purpose

    Human genome-wide CRISPR-Cas9 gRNA library, optimised by mining existing large-scale screening datasets, which provides a >60% reduction in size while preserving key information content

    Depositor

    Mathew Garnett

    Article

    Gonçalves et al Genome Biol. 2021 Jan 21;22(1):40. doi:

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    May 20, 2021

    Availability

    Academic Institutions and Nonprofits only

16. Human sgRNA library Brunello in lentiCRISPRv2

    Pooled Library

    #73179

    Purpose

    Human sgRNA library in backbone lentiCRISPRv2 targeting 19,114 genes and containing 76,441 unique sgRNAs along with 1000 non-targeting controls

    Depositor

    David Root, John Doench

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Has Service

    Lentiviral Prep

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available since

    Feb. 9, 2016

    Availability

    Academic Institutions and Nonprofits only

17. Human sgRNA library Brunello in lentiGuide-Puro

    Pooled Library

    #73178

    Purpose

    Human sgRNA library in backbone lentiGuide-Puro targeting 19,114 genes and containing 76,441 unique sgRNAs along with 1000 non-targeting controls

    Depositor

    David Root, John Doench

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Has Service

    Lentiviral Prep

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available since

    Feb. 9, 2016

    Availability

    Academic Institutions and Nonprofits only

18. ACER

    Pooled Library

    #226117

    Purpose

    The Advanced Catalogue of Epigenetic Regulators (ACER) library allows scientists to study how different epigenetic proteins influence gene activity and contribute to diseases.

    Depositor

    Rui Lu

    Article

    Zhou et al Blood. 2024 Aug 16:blood.2023023644. doi

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Oct. 29, 2024

    Availability

    Academic Institutions and Nonprofits only

19. Mouse sgRNA library Brie in lentiCRISPRv2

    Pooled Library

    #73632

    Purpose

    Mouse sgRNA library in backbone lentiCRISPRv2 containing 78,637 unique sgRNAs targeting 19,674 genes along with 1000 non-targeting controls

    Depositor

    David Root, John Doench

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available since

    Feb. 25, 2016

    Availability

    Academic Institutions and Nonprofits only

20. Mouse sgRNA library Brie in lentiGuide-Puro

    Pooled Library

    #73633

    Purpose

    Mouse sgRNA library in backbone lentiGuide-Puro containing 78,637 unique sgRNAs targeting 19,674 genes along with 1000 non-targeting controls

    Depositor

    David Root, John Doench

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Has Service

    Lentiviral Prep

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available since

    Feb. 25, 2016

    Availability

    Academic Institutions and Nonprofits only