375 results

1. Drosophila_sgRNA_group_3

   Pooled Library

   #134584

   Purpose

   Targets all other Drosophila genes not included in Groups 1 and 2

   Depositor

   Norbert Perrimon

   Article

   Viswanatha et al Elife. 2018 Jul 27;7. pii: 36333. doi: 1

   Expression

   Insect

   Species

   Drosophila melanogaster

   Use

   CRISPR

   Available since

   Feb. 25, 2020

   Availability

   Academic Institutions and Nonprofits only

2. Drosophila_sgRNA_group_1

   Pooled Library

   #134582

   Purpose

   Targets kinases, phosphatases, and Drosophila orthologs of drug targets

   Depositor

   Norbert Perrimon

   Article

   Viswanatha et al Elife. 2018 Jul 27;7. pii: 36333. doi: 1

   Expression

   Insect

   Species

   Drosophila melanogaster

   Use

   CRISPR

   Available since

   Feb. 25, 2020

   Availability

   Academic Institutions and Nonprofits only

3. Bassik lab Human CRISPR-Cas9 Deletion Library - Proteostasis

   Pooled Library

   #101930

   Purpose

   Bassik lab Human CRISPR-Cas9 Deletion Library - Proteostasis. Coexpresses mCherry.

   Depositor

   Michael Bassik

   Article

   Morgens et al Nat Commun. 2017 May 5;8:15178. doi: 10.

   Expression

   Mammalian

   Use

   CRISPR

   Available since

   May 23, 2018

   Availability

   Academic Institutions and Nonprofits only

4. The Human Druggable CRISPR library

   Pooled Library

   #200013

   Purpose

   The library contains ~10,000 sgRNAs targeting 1,980 human genes (5 sgRNAs per gene and 100 nontargeting control sgRNAs).

   Depositor

   Lianxin Liu

   Article

   Zheng et al Adv Sci (Weinh). 2023 Aug;10(22):e220679

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   May 9, 2023

   Availability

   Academic Institutions and Nonprofits only

5. Toronto KnockOut version 3 library (TKOv3)

   Pooled Library

   #90294

   Purpose

   Optimized library offering improved accuracy, efficiency, and scalability for CRISPR screens compared to TKOv1

   Depositor

   Jason Moffat

   Article

   Hart et al G3 (Bethesda). 2017 Aug 7;7(8):2719-2727

   Available since

   May 5, 2017

   Availability

   Academic Institutions and Nonprofits only

6. TRE-MPRA_minCMV Library

   Pooled Library

   #201012

   Purpose

   Massively parallel reporter assay (MPRA) library with minCMV promoter

   Depositor

   Justin English

   Article

   Zahm et al bioRxiv. 2023 May 11:2023.05.11.539703.

   Expression

   Mammalian

   Use

   Luciferase

   Available since

   Oct. 31, 2023

   Availability

   Academic Institutions and Nonprofits only

7. Human Lipid Droplet and Metabolism Library

   Pooled Library

   #191535

   Purpose

   Lentiviral CRISPR library targeting 1,196 genes related to lipid droplet biology and cell metabolism.

   Depositor

   James Olzmann

   Article

   Roberts et al Dev Cell. 2023 Jul 18:S1534-5807(23)0033

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   March 1, 2023

   Availability

   Academic Institutions and Nonprofits only

8. Human DNA Binding Domain-Focused CRISPR Knockout Library

   Pooled Library

   #123334

   Purpose

   Expresses gRNA targeting the DNA binding domain of human transcription factors.

   Depositor

   Christopher Vakoc

   Article

   Huang et al Genes Dev. 2018 Jul 1;32(13-14):915-928.

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   May 2, 2019

   Availability

   Academic Institutions and Nonprofits only

9. Mouse Brie kinome pooled library, guides 1-4 in lentiCRISPRv2 backbone

   Pooled Library

   #75317

   Purpose

   Mouse sgRNA library in backbone lentiCRISPRv2 targeting 713 kinase genes and containing 2,852 unique sgRNAs along with 100 non-targeting controls

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Available since

   June 27, 2016

   Availability

   Academic Institutions and Nonprofits only

10. Ma-PylRS-lib1

    Pooled Library

    #224585

    Purpose

    Pyrrolysine tRNA synthetase library to generate new genetic code expansion (GCE) systems for site-specific incorporation of non-canonical amino acids (ncAAs) into proteins.

    Depositor

    Ryan Mehl

    Article

    Avila-Crump et al ACS Chem Biol. 2022 Dec 16;17(12):3458-3

    Expression

    Bacterial

    Species

    Methanomethylophilus alvus

    Available since

    Jan. 6, 2025

    Availability

    Academic Institutions and Nonprofits only