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Human ubiquitination-related proteins CRISPR KO library

Pooled library

#174592

Purpose

Targets human ubiquitation-related proteins and deubiquitinating enzymes.

Depositor

Juan Bonifacino

Publication

Jia et al Elife. 2019 Nov 6;8. pii: 50034. doi: 10

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Nov. 30, 2021

Availability

Academic Institutions and Nonprofits only

Cited by

1 Article
Human Epigenetic Knockout Library

Pooled library

#162256

Purpose

Knockout library that targets human epigenetic genes.

Depositor

Kivanc Birsoy

Publication

Williams et al Cell Metab. 2020 Apr 7;31(4):852-861.e6.

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Nov. 17, 2020

Availability

Academic Institutions and Nonprofits only
RNA-binding protein pooled CRISPR knockout library

Pooled library

#141438

Purpose

Knockout library targeting RNA-binding proteins with 10 guide RNAs per target.

Depositor

Eugene Yeo

Publication

Wheeler et al Nat Methods. 2020 May 11. pii: 10.1038/s

Expression

Mammalian

Use

CRISPR and Lentiviral

Available since

May 28, 2020

Availability

Academic Institutions and Nonprofits only

Cited by

5 Articles
Mouse Chromatin Regulator Library

Pooled library

#200011

Purpose

Knockout library targeting a comprehensive set of mouse genes with annotated function as chromatin regulators.

Depositor

Bradley Bernstein, Gabriel Griffin, Robert Manguso

Publication

Griffin et al Nature. 2021 Jul;595(7866):309-314. doi:

Expression

Mammalian

Use

CRISPR and Lentiviral

Available since

Dec. 15, 2023

Availability

Academic Institutions and Nonprofits only
The Human Druggable CRISPR library

Pooled library

#200013

Purpose

Knockout library containing ~10,000 sgRNAs targeting 1,980 human druggable genes (5 sgRNAs per gene and 100 non-targeting control sgRNAs).

Depositor

Lianxin Liu

Publication

Zheng et al Adv Sci (Weinh). 2023 Aug;10(22):e220679

Expression

Mammalian

Use

CRISPR and Lentiviral

Available since

May 9, 2023

Availability

Academic Institutions and Nonprofits only
lentiCRISPRv2_ISG

Pooled library

#125753

Purpose

Knockout library targeting a set of human interferon-stimulated genes (ISGs).

Depositor

Michael Emerman, Molly OhAinle

Publication

Roesch et al Retrovirology. 2018 Mar 20;15(1):26. doi

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

May 7, 2020

Availability

Academic Institutions and Nonprofits only

Cited by

1 Article
Perturb-seq GBC library

Pooled library

#85968

Purpose

Barcode library for cloning gRNA sublibraries for single cell CRISPR analysis.

Depositor

Jonathan Weissman

Publication

Adamson et al Cell. 2016 Dec 15;167(7):1867-1882.e21.

Expression

Mammalian

Use

CRISPR and Lentiviral

Available since

Feb. 14, 2017

Availability

Academic Institutions and Nonprofits only

Cited by

8 Articles
Human DNA Binding Domain-Focused CRISPR Knockout Library

Pooled library

#123334

Purpose

Designed for genomic deletion screening of transcription factors by targeting the DNA binding domains.

Depositor

Christopher Vakoc

Publication

Huang et al Genes Dev. 2018 Jul 1;32(13-14):915-928.

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

May 2, 2019

Availability

Academic Institutions and Nonprofits only

Cited by

1 Article
Mouse Cardiac Transcriptional Regulators CRISPR Knockout Library

Pooled library

#138015

Purpose

AAV library targeting transcriptional regulators expressed in cardiomyocytes.

Depositor

William Pu

Publication

VanDusen et al Nat Commun. 2021 Jul 21;12(1):4442. doi:

Species

Mus musculus

Use

AAV, CRISPR, and Cre/Lox

Available since

April 17, 2020

Availability

Academic Institutions and Nonprofits only
Mouse Cherry Brie Pooled Library

Pooled library

#170511

Purpose

Genome-wide knockout library. It is identical to the Brie library #73633, replacing Puromycin resistance with mCherry.

Depositor

Pavel Tolar

Publication

Newman et al bioRxiv 2021.03.02.433398

Expression

Mammalian

Species

Synthetic

Use

CRISPR and Lentiviral

Available since

Sept. 9, 2021

Availability

Academic Institutions and Nonprofits only

Cited by

2 Articles
Inzolia library in pRDA_550

Pooled library

#209552

Purpose

The human, genome-wide, CRISPR knockout enAsCas12a gRNA library targets single genes and paralog pairs, triples, and quads with arrays of 4 gRNAs.

Depositor

John Doench

Publication

Esmaeili Anvar et al Nat Commun. 2024 Apr 27;15(1):3577. doi:

Use

CRISPR and Lentiviral

Available since

Dec. 5, 2023

Availability

Academic Institutions and Nonprofits only
pSMAL-CellTag-multi-v1 barcode library

Pooled library

#206045

Purpose

The CellTag multi library of barcodes can be used to clonally label cells with DNA barcodes. These barcodes can be profiled directly with single-cell RNA and ATAC sequencing, to allow clonal tracking

Depositor

Samantha Morris

Publication

Jindal et al Nat Biotechnol. 2023 Sep 25. doi: 10.103

Use

Lentiviral

Available since

Nov. 2, 2023

Availability

Academic Institutions and Nonprofits only
Human Lipid Droplet and Metabolism Library

Pooled library

#191535

Purpose

Targets 1,196 genes related to lipid droplet biology and cell metabolism.

Depositor

James Olzmann

Publication

Roberts et al Dev Cell. 2023 Jul 18:S1534-5807(23)0033

Expression

Mammalian

Use

CRISPR and Lentiviral

Available since

March 1, 2023

Availability

Academic Institutions and Nonprofits only

Cited by

1 Article
Mouse messenger-RBP sgRNA library

Pooled library

#169082

Purpose

Retroviral knockout library targeting mouse mRNA binding proteins with 10 sgRNAs/gene.

Depositor

Martin Turner

Publication

Turner et al eLife. 2022 Apr 22;11. pii: 72313. doi:

Expression

Mammalian

Species

Mus musculus

Use

CRISPR and Lentiviral

Available since

Sept. 10, 2021

Availability

Academic Institutions and Nonprofits only
Inzolia library in pRDA_052

Pooled library

#209551

Purpose

The human, genome-wide, CRISPR knockout enAsCas12a gRNA library targets single genes and paralog pairs, triples, and quads with arrays of 4 gRNAs.

Depositor

John Doench

Publication

Esmaeili Anvar et al Nat Commun. 2024 Apr 27;15(1):3577. doi:

Use

CRISPR and Lentiviral

Available since

Dec. 5, 2023

Availability

Academic Institutions and Nonprofits only
SPECS library

Pooled library

#127842

Purpose

For performing high-throughput cell state-specific synthetic promoter screening

Depositor

Timothy Lu

Publication

Wu et al Nat Commun. 2019 Jun 28;10(1):2880. doi:

Species

Synthetic

Use

Lentiviral

Available since

Aug. 22, 2020

Availability

Academic Institutions and Nonprofits only

Cited by

1 Article
ACER

Pooled library

#226117

Purpose

Contains 748 traditional and newly predicted epigenetic regulators using epigenetic network analyses that integrated gene codependency (DepMap) and protein-protein interaction data (BioPlex).

Depositor

Rui Lu

Publication

Zhou et al Blood. 2024 Aug 16:blood.2023023644. doi

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Oct. 29, 2024

Availability

Academic Institutions and Nonprofits only
FNLCR CRISPRa Cell Surface

Pooled library

#207471

Purpose

CRISPR-based activation library with guide RNAs targeting all cell surface proteins.

Depositor

Raj Chari

Publication

Yang et al Sci Adv. 2024 Feb 16;10(7):eadj2445. doi

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Jan. 24, 2024

Availability

Academic Institutions and Nonprofits only
Human messenger-RBP sgRNA library

Pooled library

#168791

Purpose

Knockout library targeting human mRNA binding proteins with 10 sgRNAs/gene.

Depositor

Martin Turner

Publication

Turner et al CRISPR J. 2021 Jun;4(3):427-437. doi: 10

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

July 30, 2021

Availability

Academic Institutions and Nonprofits only
S. rosetta Col- cDNA amplified library

Pooled library

#62843

Purpose

amplified library of Salpingoeca rosetta

Depositor

Nicole King

Publication

Fairclough et al Genome Biol. 2013 Feb 18;14(2):R15. doi:

Expression

Bacterial

Species

Salpingoeca rosetta

Available since

June 16, 2015

Availability

Academic Institutions and Nonprofits only

Showing: 1 - 20 of 41 results

Results per page:

Sort results by:

More Filters

We narrowed to 41 results for: lat

Human ubiquitination-related proteins CRISPR KO library

Human Epigenetic Knockout Library

RNA-binding protein pooled CRISPR knockout library

Mouse Chromatin Regulator Library

The Human Druggable CRISPR library

lentiCRISPRv2_ISG

Perturb-seq GBC library

Human DNA Binding Domain-Focused CRISPR Knockout Library

Mouse Cardiac Transcriptional Regulators CRISPR Knockout Library

Mouse Cherry Brie Pooled Library

Inzolia library in pRDA_550

pSMAL-CellTag-multi-v1 barcode library

Human Lipid Droplet and Metabolism Library

Mouse messenger-RBP sgRNA library

Inzolia library in pRDA_052

SPECS library

ACER

FNLCR CRISPRa Cell Surface

Human messenger-RBP sgRNA library

S. rosetta Col- cDNA amplified library

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