We narrowed to 497 results for: RAP
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TypeCollection...portfolio of biomolecular tools and emphasizes their rapid and broad dissemination to the research community...for Cre-dependent expression of Venus-tagged parapinopsin driven by the CAG promoter. Used for photoswitchable...for Cre-dependent expression of Venus-tagged parapinopsin driven by the Ef1a promoter. Used for photoswitchable...version of DLX enhancer). AAV vector for strong & rapid SYFP2 expression in forebrain GABAergic interneurons...
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Rett Syndrome
TypeCollection...MECP2 reactivation, RNA editing, gene replacement therapy, RNA trans-splicing, and protein replacement to...They are also an important tool for developing therapeutic strategies to treat Rett syndrome and restore...disease and for the development of successful therapeutics. ATCC - (Link opens in a new window) LUHMES ...CRISPR Tools CRISPR technology is a promising therapeutic approach for precise editing of mutations in ... -
Mammalian RNAi Tools
TypeCollection...siRNAs): mechanism, therapeutic targets, and delivery strategies for cancer therapy . International Journal... genes with potentially harmful mutations in therapeutic settings. As a tool in mammalian cell systems... -
Antibody Plasmid Collection
TypeCollection...single mammalian expression vector A tool kit for rapid cloning and expression of recombinant antibodies...2006 Dec 7;6:46. John McCafferty CRISPR system to rapidly engineer the constant immunoglobulin domains to...single domain antibodies for the conformational trapping of membrane proteins. Elife. 2018 May 24;7. ... -
Arf GTPase Family
TypeCollection...Bacterial (pET) GAP Arap1 (CENTD2) 116985 1450 GAP Arap2 (CENTD1) 116984 1704 GAP Arap3 (CENTD3) 64411 1544... -
Viral Vectors
TypeCollection... Adenovirus vectors for gene therapy, vaccination and cancer gene therapy. Curr Gene Ther. 2013 Dec;13...oncolytic) adenoviruses are utilized for cancer therapy because of their ability to preferentially infect... -
University of Florida Serotype Testing Panel for the Eye and Brain
TypeCollection...Transduction optimization of AAV vectors for human gene therapy of glaucoma and their reversed cell entry characteristics...Display Exceptional Characteristics for Retinal Gene Therapy. Mol Ther . Jun 3;28(6):1464-1478. PMID: 32304666... -
Zhang Lab CRISPR Page
TypeCollection...SapI, which will reveal sticky ends to enable the rapid ligation of annealed and phosphorylated oligos designed... -
Plasmids for Stem Cell Research
TypeCollection... an excellent unlimited stem cell source for therapeutic use. Since 2006, scientists have developed many...e16. Yang iPSCs Bipolar Neurons Lentiviral Human Rapid neurogenesis through transcriptional activation ...Weiss iPSCs & iPSC-NPCs Neurons Lentiviral Human Rapid Ngn2-induction of excitatory neurons from hiPSC-... -
Fluorescent Protein Guide: Biosensors
TypeCollection...Monitoring the action of redox-directed cancer therapeutics using a human peroxiredoxin-2-based probe. Nat...Single fluorescent protein biosensor for maltose Rapid construction of metabolite biosensors using domain-insertion...Single fluorescent protein biosensor for trehalose Rapid construction of metabolite biosensors using domain-insertion...sensors A Genetically Encoded Fluorescent Sensor for Rapid and Specific In Vivo Detection of Norepinephrine... -
AAV Molecular Tools
TypeCollection...transactivators and tools for affinity purification (TRAP)....affinity purification (which can be used for viral TRAP). ID Name Expression System Activity Serotype PI... -
TALEN Guide
TypeCollection...specific gene or your anxiously investigating gene therapy options for a rare disease in humans, TAL effectors... key tool in your plasmid toolbox. Addgene has rapidly become an important resource for this new technology... -
Zebrafish Plasmid Collection
TypeCollection...of genetics and developmental biology. With its rapid development (embryogenesis is complete in ~3 days...MAZERATI platform - Leonard Zon Lab. A platform to rapidly model potential cancer drivers in vivo. Biotagging... -
COVID-19 Resources
TypeCollection... DETECTR to detect coronavirus - A protocol for rapid detection of the 2019 novel coronavirus SARS-CoV...protease Mpro now available from Xiaokun Shu's lab. A rapid, highly sensitive and open-access SARS-CoV-2 detection... -
TALENs for Endogenous Zebrafish Genes
TypeCollection...TGCCAGGCTCGTAGCCTGttccaggctgatgccccTCAGCCCAGATGGGAGGA arap3a TAL3026 & TAL3027 TGGCAACAATCGGTCCGTgctcagatgcagaggaCCTGTTGGCTTCCATCCA...TCAGCTGGAGCGCTTTTCtgcagatctgctggatACTCATGGTGAGAGCAAA trappc11 TAL3582 & TAL3583 TCCTATGAGTGGTACATTcctaaagggattctgaAGACGGGCTGGATGAACA... -
Luciferase Plasmid Collection
TypeCollection...Lentiviral Nadav Ahituv 212935 pGL4.84(hRlucCP/Puro) RapidResponse™ Renilla Vector for investigating regions controlling...FRB-Nluc : Split firefly luciferase reporter of rapamycin-inducible interaction. nLuc and cLuc : Constructs... -
CRISPR History and Development for Genome Engineering
TypeCollection...technologies. Biotechnology companies are exploring therapeutic applications of CRISPR to treat genetic disease...ethics associated with CRISPR in agricultural and therapeutic applications. Despite the ethical controversies... -
Genomic Deletions in Mammalian Cell Lines
TypeCollection...the efficiency of biallelic modification, ease of rapid identification by PCR, predictability of loss-of-function... methods, perspectives for drug delivery, gene therapy and research. Gehl J. Acta Physiologica... -
CRISPR Plasmids - Empty gRNA Vectors
TypeCollection... and Dicot Plants Plant PCR-based procedure to rapidly generate multiple sgRNA expression cassettes, which...transcript Bullock pCRISPathBrick Bacteria Allows rapid modular assembly of natural type II-A CRISPR arrays... -
CRISPR Guide
TypeCollection...comparative simplicity and adaptability, CRISPR rapidly became the most popular genome engineering approach...regulate known phenotypes, including resistances to chemotherapy drugs and toxins, cell viability, and tumor ...natural and engineered CjCas9 orthologs. Molecular Therapy , 31 (4), 1177–1187. PMID: 36733251 Harrington,...