We narrowed to 87 results for: MAL

...DHLAG, HLADG, Ia-GAMMA CD8A CD8a molecule CD8, Leu2, MAL, p32 CD8B CD8b molecule CD8B1, LYT3, Leu2, Ly3, MGC119115...cytotoxicity triggering receptor 3 1C7, CD337, LY117, MALS, NKp30 NFAT5 nuclear factor of activated T-cells...TRAP, gp39, hCD40L CD8A CD8a molecule CD8, Leu2, MAL, p32 CD8B CD8b molecule CD8B1, LYT3, Leu2, Ly3, MGC119115... HSCR, HSCR2 EGF epidermal growth factor (beta-urogastrone) HOMG4, URG EGFR epidermal growth factor receptor...Categories Plasmid Tables Additional Resources Mammalian organisms are exposed to millions of potential...Chemokines Chemokines, or chemotactic cytokines, are small proteins that can be secreted by immune cells and...X-associated protein - SHFM1 split hand/foot malformation (ectrodactyly) type 1 DSS1, ECD, SEM1, SHFD1...

...are sporadic, having no prior family history. A small percentage (5–10%) are familial ALS cases having...These familial cases, usually inherited in an autosomal dominant manner, are associated with known genetic... Disease Huntington’s disease (HD) is a fatal autosomal dominant genetic disorder that causes the progressive...difficulty speaking and swallowing. HD is caused by abnormal expansion of a repeating CAG triplet series within...mutated HTT gene will have huntingtin proteins with abnormally long polyglutamine sequences. These glutamine-rich...medication and surgery. PD primarily involves the malfunction and death of dopamine-producing neurons in the... specific known cause) nature of the disease, a small portion of cases can be attributed to known genetic...

...RPS6KA2 RPS6KA3 RPS6KA6 Ribosomal protein S6 kinase RPS6KB RPS6KB1 RPS6KB2 Ribosomal protein S6 kinase B1...collection of plasmids for the Ras pathway. Ras is a small GTPase and constitutively active Ras is the most...Plasmids Ras Gene List Resources Background Ras is a small GTPase and is a member of the G protein (guanine...addition and removal of a phosphate group. Under normal physiological conditions GTPases play prominent...factor ECT2 Epithelial cell transforming 2 EGFR Epidermal growth factor receptor EIF4EBP EIF4EBP1 EIF4EBP2...Ras-related C3 botulinum toxin substrate (rho family, small GTP binding protein Rac) RAF AFAF BRAF RAF1 Serine...

...Return to top Plasmids Encoding Mammalian Genes or Inserts Several mammalian genes have been identified as...SARS-CoV-2 Plasmids Other Coronavirus Plasmids Mammalian Targets General Plasmid Tools Pooled Libraries...encoding SARS-CoV-2 proteins, (spike protein, S; small envelope protein, E; nucleocapsid protein, N; and... SARS-CoV-2 plasmids for E. coli , yeast, and mammalian expression, and spike protein...al., 2020). Cathepsin L plasmids - a cysteine endosomal protease that triggers proteolysis of SARS-CoV... I., Holmes, E. C., & Garry, R. F. (2020). The proximal origin of SARS-CoV-2 . Nature medicine, 26 (4)...

...localization. ACP and MCP tags ACP- and MCP-tags are small protein tags based on the acyl carrier protein. ...SNAP-tag Empty backbone for stable and transient mammalian expression 101133 pSNAP-CaaX Control Plasmid SNAP-tag...CLIP-tag Empty backbone for stable and transient mammalian expression 101134 pCLIPf-H2B Control Plasmid CLIP-tag...Vector ACP/MCP-tag Empty backbone for transient mammalian expression 101126 pACP-tag (m)- 2 Vector ACP/MCP-tag...MCP-tag Empty backbone for stable and transient mammalian expression 101132 pMCP-GPI Control Plasmid ACP... Marahiel MA.1998. Peptide bond formation in nonribosomal peptide biosynthesis. Catalytic role of the ...

...Dammeyer 54520 mCherry-Peroxisomes-2 Peroxisomes Peroximal targeting signal (SKL) mCherry* Michael Davidson...Davidson 36203 pmTurquoise2-Peroxi Peroxisomes Peroximal targeting signal (SRL) mTurquoise2 Dorus Gadella ... Misteli 137806 mNeonGreen-peroxi Peroxisomes Peroximal targeting signal (SKL) mNeonGreen Dorus Gadella...Gadella 85063 pmScarlet_peroxisome_C1 Peroxisomes Peroximal targeting signal (SRL) mScarlet Dorus Gadella ...Gadella 189769 pmScarlet3-Peroxi_C1 Peroxisomes Peroximal targeting signal (SRL) mScarlet3 Dorus Gadella 61202...61202 pCMU-PERr Peroxisomes (Plants) Peroximal targeting signal (SKL) mCherry Maria Harrison 55146 mCherry-TOMM20...responsible for forming connections and adhesions between animal cells. They are important for holding cell structures...

...bind to a small molecule, the reporter plasmid can be used to detect the presence of that small molecule...Signal peptides for periplasmic localization: PelB, MalE, OmpA ID Plasmid Promoter Tags PI Additional Addgene...visualization inside living or fixed bacterial and mammalian cells. Addgene Blog A Guide to Selecting Fluorescent... Fluorescent Protein Guide for a selection of mammalian and bacterial FRET-related vectors and standards...expression levels can be controlled by a variety of small molecules, light, and temperature, in different ...control the expression of up to twelve genes using small-molecule inducers in the same E. coli strain. Addgene...

...Includes a wide range of reference genomes, including animals, plants, bacteria, fungi, protists, and viruses...Link opens in a new window) Program for designing optimal gRNAs. Provides feedback on number of potential...human. Developed by the George Church Lab . CRISPR Optimal Target Finder (Link opens in a new window) Identification...cloning pCRISPR PDF, 109 KB Mendenhall and Myers Mammalian: FLAG tagging endogenous proteins pFETCh_Donor...Orkin and Bauer Protocol for Genomic Deletions in Mammalian Cell Lines pSpCas9(BB) (pX330) PDF, 330 KB Parrott...

...GRE or transgenic animal Oligodendrocytes - AAV-PHP.eB with GRE or transgenic animal Brain vascular cells...GRE or transgenic animal L5 & Inhibitory - AAV-PHP.eB with GRE or transgenic animal L2/3 & L4 - AAV.CAP-B10...with GRE or transgenic animal Excitatory - AAV.PHP.N with GRE or transgenic animal For PNS applications ...

...BiT (LgBiT; 18 kDa) subunit and a small complementary peptide, Small BiT (SmBiT; 11 amino acids). This... and extracellular applications where you want minimal disruption of endogenous protein expression and...protein expression systems including E. coli , mammalian cells, and cell-free systems. NanoBiT Assays NanoLuc...association, and dissociation. HiBiT Fusions HiBiT is a small, multifunctional epitope tag enabling precise protein...

...fluorophore and targeted to the neuronal soma and proximal dendrites in a viral vector Hillel Adesnik 107708...channelrhodopsin ChroME targeted to the neuronal soma and proximal dendrites and separated from nuclear mRuby3 by...export signal and targeted to the neuronal soma and proximal dendrites under the control of internal ribosome...genetically encoded dopamine sensor RdLight1 in mammalian cells. Lin Tian 125708-AAV9 pAAV-hSynapsin1-RdLight1...genetically encoded dopamine sensor RdLight1 in mammalian neurons. Lin Tian 127090-PHPeB pAAV-CAG-DIO-ChR2... in AAV production vector expressed under the mammalian promoter (EF1a) Francois St-Pierre 179460-AAV1...AAV production vector under the control of the mammalian promoter (EF1a) Francois St-Pierre 179463-AAV9...

... that function in mammalian cells can be used to attentuate RNA levels. In mammalian systems, Cas13a does... RNA Targeting CRISPR Plasmids: RNA Targeting Mammalian Bacteria Plant Resources Type VI CRISPR systems... other CRISPR topics, read our CRISPR Guide . Mammalian ID Plasmid Gene/Insert Promoter Selectable Marker...

... CRISPR Base Edit CRISPR Plasmids: Base Edit Mammalian Bacteria Plant Yeast Zebrafish Resources Two classes...and they can convert cytidine to uridine within a small editing window near the PAM site. Uridine is subsequently...editors are designed to work in a very narrow window proximal to the PAM sequence, some base editing systems... other CRISPR topics, read our CRISPR Guide . Mammalian ID Plasmid Gene/Insert Promoter Selectable Marker...

...nuclease system to facilitate genome editing in mammalian cells (Cong et al ., Science 2013, Ran et al ....Plasmids The CRISPR/Cas system can be implemented in mammalian cells by co-expressing the S. pyogenes Cas9 (SpCas9... are two sets of 3 vectors each available for mammalian endogenous gene activation using SAM: Addgene ...adeno-associated virus (AAV). The single vector system uses a smaller Cas9 from S. aureus (SaCas9) that has been human...In vivo interrogation of gene function in the mammalian brain using CRISPR-Cas9. Swiech L, Heidenreich...

... available for expression in mammalian systems and Drosophila. Mammalian ID Plasmid Gene/Insert Promoter...Libraries gRNAs Empty gRNA Vectors By Species Mammalian Bacteria Drosophila Plant C. elegans Yeast Zebrafish...

...CRISPR RNA Editing CRISPR Plasmids: RNA Editing Mammalian Resources Type VI CRISPR systems, including the...truncation retain RNA editing capabilities but are small enough to be packaged in AAV particles. Figure 1... other CRISPR topics, read our CRISPR Guide . Mammalian ID Plasmid Gene/Insert PI Publication Return to...

...tracking of reprogramming factors Fluorescent tagged episomals for stoichiometric induced pluripotent stem cell...Fibroblasts Cholinergic Neurons Lentiviral Human Small molecules enable neurogenin 2 to efficiently convert... Cell Rep. 2016 Jan 5;14(1):115-28. Zhang Adult Dermal Fibroblasts Neurons Lentiviral Human REST suppression...

...conformational changes within a protein. Biosensors Monitor small biomolecules or other physiological intracellular... study molecular processes in organs and whole animals. Additional Resources at Addgene Optogenetics Guide...Chemogenetics Guide | Chemogenetics Plasmids Use small molecules to activate or inhibit engineered receptors...

...delivery tools that effectively transduce many mammalian cell types. AAV is used in a wide range of experiments...in-stock AAV preps are affordable, available in small volumes, and ready to ship. All viral vector preps...Rabies Virus-Based Serotype Serotype Testing Samples Small samples of control AAV vectors for trial purposes...

... CRISPR Plasmids: CRISPR Transposases (CASTs) Mammalian Bacteria Resources CRISPR-associated transposases... used in bacteria genome editing, though some mammalian systems have been developed. Figure 1: Overview... other CRISPR topics, read our CRISPR Guide . Mammalian ID Plasmid Gene/Insert Promoter Selectable Marker...