We narrowed to 4,276 results for: 424

1. pRK5 FLAG membrane-bound lipin-1 (TMD)

   Plasmid

   #120277

   Purpose

   Expression of ER/Golgi-tethered lipin-1 in mammalian cells

   Depositor

   Sirio Dupont

   Article

   Romani et al Nat Cell Biol. 2019 Mar;21(3):338-347. d

   Insert

   Lipin-1 (Lpin1 Mouse)
   

   Use

   Tags

   FLAG and in-frame fusion with the TMD Golgi-local…

   Expression

   Mammalian

   Mutation

   Promoter

   CMV

   Available since

   March 18, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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2. pW210-pPB-GA-inducible-CRISPRa-sa_dCas9-VPR-hygR

   Plasmid

   #170808

   Purpose

   PiggyBac vector to express GA-inducible VPR-Sa_dCas9 with hygromycin resistance

   Depositor

   Kenneth Yamada

   Article

   Wang et al Cell. 2021 Jul 8;184(14):3702-3716.e30.

   Inserts

   GID1-VPR-IRES-HygR
   GAI-tagBFP-Sa_dCas9 (GAI Mustard Weed, S. aureus, Synthetic)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   Synonymous mutation in PYL1 to remove XhoI site (…

   Promoter

   Available since

   June 8, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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3. pIS1 INSIG2

   Plasmid

   #60798

   Purpose

   Luciferase reporter to measure miR-155 mediated differential repression. Contains INSIG2 3' UTR and wild-type miR-155 sites

   Depositor

   David Bartel

   Article

   Nam et al Mol Cell. 2014 Mar 20;53(6):1031-43. doi

   Insert

   INSIG2 3'UTR and wild-type miR-155 binding site (INSIG2 Human)
   

   Use

   Luciferase

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   thymidine kinase (HSV-TK promoter)

   Available since

   Oct. 20, 2014

   Availability

   Academic Institutions and Nonprofits only

   

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4. pPB-cT3G-cERP2-JUN

   Plasmid

   #192895

   Purpose

   Barcoded piggybac transposon vector with Dox-inducible expression of JUN

   Depositor

   George Church

   Article

   Pierson Smela et al Elife. 2023 Feb 21;12:e83291. doi: 10.75

   Insert

   JUN (JUN Human)
   

   Use

   Tags

   HA

   Expression

   Mammalian

   Mutation

   Promoter

   TET3G-miniCMV

   Available since

   Feb. 24, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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5. TFORF2078

   Plasmid

   #141910

   Purpose

   Lentiviral vector for overexpressing transcription factor ORFs with unique 24-bp barcodes. Barcodes facilitate identification of transcription factors in pooled screens.

   Depositor

   Feng Zhang

   Article

   Joung et al Cell. 2023 Jan 5;186(1):209-229.e26. doi

   Insert

   FLI1 (FLI1 Human)
   

   Use

   Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   EF1a

   Available since

   Jan. 5, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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6. TFORF1118

   Plasmid

   #141796

   Purpose

   Lentiviral vector for overexpressing transcription factor ORFs with unique 24-bp barcodes. Barcodes facilitate identification of transcription factors in pooled screens.

   Depositor

   Feng Zhang

   Article

   Joung et al Cell. 2023 Jan 5;186(1):209-229.e26. doi

   Insert

   SKP2 (SKP2 Human)
   

   Use

   Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   EF1a

   Available since

   Jan. 5, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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7. pLenti.PGK.blast-Flag-MFF-S155,172A

   Plasmid

   #74380

   Purpose

   Lentiviral expression vector containing flag tagged S155,172A MFF isoform 5 mutant

   Depositor

   Reuben Shaw

   Article

   Toyama et al Science. 2016 Jan 15;351(6270):275-81. d

   Insert

   Flag-MFF (MFF Human)
   

   Use

   Lentiviral

   Tags

   Flag

   Expression

   Mammalian

   Mutation

   Ser 155 Ala, Ser 172 Ala (Numbering based on MFF …

   Promoter

   Available since

   April 14, 2016

   Availability

   Academic Institutions and Nonprofits only

8. pLenti.PGK.blast-Flag-MFF-S155,172E

   Plasmid

   #74443

   Purpose

   Lentiviral expression vector containing flag tagged S155,172E MFF isoform 5 mutant

   Depositor

   Reuben Shaw

   Article

   Toyama et al Science. 2016 Jan 15;351(6270):275-81. d

   Insert

   Flag-MFF (MFF Human)
   

   Use

   Lentiviral

   Tags

   Flag

   Expression

   Mammalian

   Mutation

   Ser 155 Glu, Ser 172 Glu (Numbering based on MFF …

   Promoter

   Available since

   April 14, 2016

   Availability

   Academic Institutions and Nonprofits only

9. pTWIN1-His6-Ssp-Httex1-23Q-A2C-A60C

   Plasmid

   #114613

   Purpose

   Bacterial expression of Htt fragment containing exon 1, with A2C & A60C cysteine mutations and a 23 polyQ repeat

   Depositor

   Hilal Lashuel

   Article

   Warner JB et al J Am Chem Soc. 2017 Oct 18;139(41):14456

   Insert

   Huntingtin Exon1 (HTT Human)
   

   Use

   Tags

   His6-Ssp DnaB intein

   Expression

   Bacterial

   Mutation

   A2C, A60C; 23 polyQ repeat

   Promoter

   Available since

   Sept. 19, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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10. pQCXIB Flag MFF S155,172A

    Plasmid

    #74387

    Purpose

    Retroviral expression vector containing Flag tagged S155,172A MFF isoform 5 mutant

    Depositor

    Reuben Shaw

    Article

    Toyama et al Science. 2016 Jan 15;351(6270):275-81. d

    Insert

    Flag-MFF (MFF Human)
    

    Use

    Retroviral

    Tags

    Flag

    Expression

    Mammalian

    Mutation

    Ser 155 Ala, Ser 172 Ala (Numbering based on MFF …

    Promoter

    CMV

    Available since

    May 13, 2016

    Availability

    Academic Institutions and Nonprofits only

11. pIS1 mATP2B1

    Plasmid

    #60789

    Purpose

    Luciferase reporter to measure miR-155 mediated differential repression. Contains ATP2B1 3' UTR and mutated miR-155 sites

    Depositor

    David Bartel

    Article

    Nam et al Mol Cell. 2014 Mar 20;53(6):1031-43. doi

    Insert

    ATP2B1 3'UTR and mutated miR-155 binding site (ATP2B1 Human)
    

    Use

    Luciferase

    Tags

    Expression

    Mammalian

    Mutation

    mutated miR-155 binding site

    Promoter

    thymidine kinase (HSV-TK promoter)

    Available since

    Oct. 20, 2014

    Availability

    Academic Institutions and Nonprofits only

    

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12. Anti-DNAH7 [N250/21.4R]

    Plasmid

    #164158

    Purpose

    Mammalian Expression Plasmid of anti-DNAH7 (Human). Derived from hybridoma N250/21.4.

    Depositor

    James Trimmer

    Article

    Andrews et al eLife. 2019 Jan 22;8. pii: 43322. doi: 1

    Insert

    anti-DNAH7 (Homo sapiens) recombinant mouse monoclonal antibody (DNAH7 Mouse)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    dual CMV

    Available since

    Jan. 21, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

13. pTWIN1-His6-Ssp-Htt2-90-43Q-P90C

    Plasmid

    #114626

    Purpose

    Bacterial expression of Htt fragment containing amino acids 2-90, with P90C cysteine mutation and a 43 polyQ repeat

    Depositor

    Hilal Lashuel

    Article

    Warner JB et al J Am Chem Soc. 2017 Oct 18;139(41):14456

    Insert

    Huntingtin Exon1 fragment (HTT Human)
    

    Use

    Tags

    His6-Ssp DnaB intein

    Expression

    Bacterial

    Mutation

    P90C; 43 polyQ repeat

    Promoter

    Available since

    Sept. 19, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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14. pTWIN1-His6-Ssp-Htt2-90-15Q-P90C

    Plasmid

    #114611

    Purpose

    Bacterial expression of Htt fragment containing amino acids 2-90, with P90C cysteine mutation and a 15 polyQ repeat

    Depositor

    Hilal Lashuel

    Article

    Warner JB et al J Am Chem Soc. 2017 Oct 18;139(41):14456

    Insert

    Huntingtin Exon1 fragment (HTT Human)
    

    Use

    Tags

    His6-Ssp DnaB intein

    Expression

    Bacterial

    Mutation

    P90C; 23 polyQ repeat

    Promoter

    Available since

    Sept. 18, 2018

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. ATR gRNA (BRDN0001144763)

    Plasmid

    #77549

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human ATR

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    ATR (ATR Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. ATR gRNA (BRDN0001147587)

    Plasmid

    #77551

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human ATR

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    ATR (ATR Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. FASTKD2 gRNA (BRDN0001145464)

    Plasmid

    #76302

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human FASTKD2

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    FASTKD2 (FASTKD2 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. ATR gRNA (BRDN0001145195)

    Plasmid

    #77550

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human ATR

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    ATR (ATR Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. pMXS-IRES-Blast POLD1 ISCmut

    Plasmid

    #160806

    Purpose

    Express ISC mutant POLD1

    Depositor

    Richard Possemato

    Article

    Sviderskiy et al Mol Cell. 2020 Oct 28. pii: S1097-2765(2

    Insert

    POLD1 ISCmut (POLD1 Human)
    

    Use

    Retroviral

    Tags

    Expression

    Mutation

    Codon optimized C-terminal 230 amino acids, C1058…

    Promoter

    Available since

    Oct. 30, 2020

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. MAST2 gRNA (BRDN0001146731)

    Plasmid

    #76937

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human MAST2

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    MAST2 (MAST2 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge