We narrowed to 102,682 results for: SON

1. LRRK2-WT

   Plasmid

   #17609

   Depositor

   Ted Dawson

   Article

   West et al Proc Natl Acad Sci U S A. 2005 Nov 15;10

   Insert

   LRRK2 (LRRK2 Human)
   

   Tags

   His and Myc

   Expression

   Mammalian

   Available Since

   March 31, 2008

   Availability

   Academic Institutions and Nonprofits only

   

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2. AAVS1_gRNA

   Plasmid

   #196139

   Purpose

   gRNA targeting the AAVS1 locus in a third generation Cas9 backbone with GFP

   Depositor

   Jason Sheltzer

   Article

   Girish et al Science. 2023 Jul 6:eadg4521. doi: 10.11

   Insert

   AAVS1 gRNA
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Available Since

   March 10, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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3. pLVX-Puro-TDP-43-Q331K

   Plasmid

   #133761

   Purpose

   Lentiviral expression of human TDP-43 Q331K disease mutant in mammalian cells.

   Depositor

   Shawn Ferguson

   Article

   Roczniak-Ferguson et al Life Sci Alliance. 2019 Sep 16;2(5). pii

   Insert

   TDP-43 (TARDBP Human)
   

   Use

   Lentiviral

   Expression

   Mammalian

   Mutation

   Changed glutamine 331 to lysine.

   Promoter

   CMV

   Available Since

   Dec. 2, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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4. pLVX-Puro-TDP-43-A315T

   Plasmid

   #133755

   Purpose

   Lentiviral expression of human TDP-43 A315T disease mutant in mammalian cells.

   Depositor

   Shawn Ferguson

   Article

   Roczniak-Ferguson et al Life Sci Alliance. 2019 Sep 16;2(5). pii

   Insert

   TARDBP (TARDBP Human)
   

   Use

   Lentiviral

   Expression

   Mammalian

   Mutation

   Changed alanine 315 to threonine

   Promoter

   CMV

   Available Since

   Nov. 25, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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5. pLVX-Puro-TDP-43-M337V

   Plasmid

   #133759

   Purpose

   Lentiviral expression of human TDP-43 M337V disease mutant in mammalian cells.

   Depositor

   Shawn Ferguson

   Article

   Roczniak-Ferguson et al Life Sci Alliance. 2019 Sep 16;2(5). pii

   Insert

   TDP-43 (TARDBP Human)
   

   Use

   Lentiviral

   Expression

   Mammalian

   Mutation

   Changed methionine 337 to valine

   Promoter

   CMV

   Available Since

   Nov. 25, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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6. pGL3-luciferase-reporter-JAM2-SVA

   Plasmid

   #202832

   Purpose

   pGL3 luciferase reporter with JAM2 SVA cloned upstream of SV40 promoter to test effects of SVA insertion on luciferase expression

   Depositor

   Matthew Anderson

   Article

   Nadler et al Commun Biol. 2023 Mar 30;6(1):347. doi:

   Insert

   JAM2 intronic SVA
   

   Use

   Luciferase

   Expression

   Mammalian

   Promoter

   SV40

   Available Since

   July 7, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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7. pLVX-Puro-TDP-43-K263E

   Plasmid

   #133758

   Purpose

   Lentiviral expression of human TDP-43 K263E disease mutant in mammalian cells.

   Depositor

   Shawn Ferguson

   Article

   Roczniak-Ferguson et al Life Sci Alliance. 2019 Sep 16;2(5). pii

   Insert

   TDP-43 (TARDBP Human)
   

   Use

   Lentiviral

   Expression

   Mammalian

   Mutation

   Changed lysine 263 to glutamate.

   Promoter

   CMV

   Available Since

   Nov. 25, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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8. pLV-Bsd-CMV-hUCK

   Plasmid

   #195141

   Purpose

   UCK2 overexpression vector with blasticidin resistance

   Depositor

   Jason Sheltzer

   Article

   Girish et al Science. 2023 Jul 6:eadg4521. doi: 10.11

   Insert

   UCK2 (UCK2 Human)
   

   Expression

   Mammalian

   Available Since

   Feb. 3, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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9. Chr1q_Centromere-Targeting_gRNA

   Plasmid

   #195125

   Purpose

   gRNA targeting centromere-proximal location on Chromosome 1q in a third generation Cas9 backbone with GFP

   Depositor

   Jason Sheltzer

   Article

   Girish et al Science. 2023 Jul 6:eadg4521. doi: 10.11

   Insert

   Chr1q gRNA
   

   Expression

   Mammalian

   Available Since

   Feb. 3, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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10. Chr7_Centromere-Targeting_gRNA

    Plasmid

    #195129

    Purpose

    dual gRNA vector targeting centromere-proximal locations on Chromosome 7p and 7q in a third generation Cas9 backbone with GFP

    Depositor

    Jason Sheltzer

    Article

    Girish et al Science. 2023 Jul 6:eadg4521. doi: 10.11

    Insert

    Chr7 gRNA
    

    Expression

    Mammalian

    Available Since

    Feb. 6, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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11. lentiCRISPRv2.sgNf1.1

    Plasmid

    #91895

    Purpose

    sgNf1.1 for Nf1 deletion

    Depositor

    Wen Xue

    Article

    Song et al Gastroenterology. 2017 Apr;152(5):1161-1

    Insert

    sgNf1.1
    

    Use

    Lentiviral and Mouse Targeting

    Expression

    Mammalian

    Available Since

    March 16, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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12. lentiCRISPRv2.sgNf1.4

    Plasmid

    #92029

    Purpose

    sgNf1.4 for Nf1 deletion

    Depositor

    Wen Xue

    Article

    Song et al Gastroenterology. 2017 Apr;152(5):1161-1

    Insert

    sgNf1.4 for Nf1 deletion
    

    Use

    Lentiviral and Mouse Targeting

    Expression

    Mammalian

    Available Since

    April 12, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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13. Chr8q_Centromere-Targeting_gRNA

    Plasmid

    #195128

    Purpose

    gRNA targeting centromere-proximal location on Chromosome 8q in a third generation Cas9 backbone with GFP

    Depositor

    Jason Sheltzer

    Article

    Girish et al Science. 2023 Jul 6:eadg4521. doi: 10.11

    Insert

    Chr8q gRNA
    

    Expression

    Mammalian

    Available Since

    Feb. 3, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. pLVX-Puro-TDP-43-A90V

    Plasmid

    #133754

    Purpose

    Lentiviral expression of human TDP-43 A90V disease mutant in mammalian cells.

    Depositor

    Shawn Ferguson

    Article

    Roczniak-Ferguson et al Life Sci Alliance. 2019 Sep 16;2(5). pii

    Insert

    TARDBP (TARDBP Human)
    

    Use

    Lentiviral

    Expression

    Mammalian

    Mutation

    Changed alanine 90 to valine

    Promoter

    CMV

    Available Since

    Dec. 2, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. pLVX-Puro-TDP-43-P112H

    Plasmid

    #133760

    Purpose

    Lentiviral expression of human TDP-43 P112H disease mutant in mammalian cells.

    Depositor

    Shawn Ferguson

    Article

    Roczniak-Ferguson et al Life Sci Alliance. 2019 Sep 16;2(5). pii

    Insert

    TDP-43 (TARDBP Human)
    

    Use

    Lentiviral

    Expression

    Mammalian

    Mutation

    Changed proline 112 to histidine.

    Promoter

    CMV

    Available Since

    Jan. 7, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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16. Rosa26_gRNA

    Plasmid

    #196138

    Purpose

    gRNA targeting the Rosa26 locus in a thid generation Cas9 backbone with TagBFP2

    Depositor

    Jason Sheltzer

    Article

    Girish et al Science. 2023 Jul 6:eadg4521. doi: 10.11

    Insert

    Rosa26 gRNA
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Available Since

    March 8, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. pLVX-Puro-TDP-43-D169G

    Plasmid

    #133757

    Purpose

    Lentiviral expression of human TDP-43 D169G disease mutant in mammalian cells.

    Depositor

    Shawn Ferguson

    Article

    Roczniak-Ferguson et al Life Sci Alliance. 2019 Sep 16;2(5). pii

    Insert

    TDP-43 (TARDBP Human)
    

    Use

    Lentiviral

    Expression

    Mammalian

    Mutation

    Changed aspartate 169 to glycine.

    Promoter

    CMV

    Available Since

    Dec. 2, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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18. OR6K6_Deletion_gRNA2

    Plasmid

    #195196

    Purpose

    dual gRNAs for deletion of OR6K6 in a third generation Cas9 backbone with GFP

    Depositor

    Jason Sheltzer

    Article

    Girish et al Science. 2023 Jul 6:eadg4521. doi: 10.11

    Insert

    OR6K6 dual gRNA (OR6K6 Human)
    

    Expression

    Mammalian

    Available Since

    Feb. 14, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. OR6K6_Deletion_gRNA1

    Plasmid

    #195195

    Purpose

    dual gRNAs for deletion of OR6K6 in a third generation Cas9 backbone with GFP

    Depositor

    Jason Sheltzer

    Article

    Girish et al Science. 2023 Jul 6:eadg4521. doi: 10.11

    Insert

    OR6K6 dual gRNA (OR6K6 Human)
    

    Expression

    Mammalian

    Available Since

    Feb. 14, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. OR6K6_Deletion_gRNA3

    Plasmid

    #195197

    Purpose

    dual gRNAs for deletion of OR6K6 in a third generation Cas9 backbone with GFP

    Depositor

    Jason Sheltzer

    Article

    Girish et al Science. 2023 Jul 6:eadg4521. doi: 10.11

    Insert

    OR6K6 dual gRNA (OR6K6 Human)
    

    Expression

    Mammalian

    Available Since

    Feb. 14, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge