We narrowed to 6,354 results for: nls

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pGL4.10 HIF1a prom Chr5-LG4

Plasmid

#246714

Purpose

To investigate the influence of an LG4 enhancer (chr5 LG4) on HIF1a promoter activity (measured by luciferase expression)

Depositor

Glen Borchert

Article

DeMeis et al Nucleic Acids Res. 2025 Jan 11;53(2):gka

Inserts

HIF1a Promoter (HIF1A Human)
chr5 LG4 enhancer

Use

Luciferase

Mutation

WT

Available Since

Jan. 7, 2026

Availability

Academic Institutions and Nonprofits only

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TDP-43_CTD_12S→E_S305C/A326P

Plasmid

#248868

Purpose

Expresses MBP-tagged C-terminal domain of TDP-43 with 12S→E, S305C and A326P.

Depositor

Nicolas Fawzi

Article

Rizuan et al Nat Commun. 2025 Nov 26;16(1):10528. doi

Insert

TDP-43_CTD_12S→E_S305C/A326P (TARDBP Human)

Tags

6xHis tags-MBP

Expression

Bacterial

Mutation

changed S292E, S369E, S377E, S379E, S387E, S389E,…

Available Since

Dec. 3, 2025

Availability

Academic Institutions and Nonprofits only

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pGL4.10 EXOC3prom SV40

Plasmid

#246713

Purpose

To investigate the influence of a universal enhancer (SV40) on EXOC3 promoter activity (measured by luciferase expression)

Depositor

Glen Borchert

Article

DeMeis et al Nucleic Acids Res. 2025 Jan 11;53(2):gka

Inserts

EXOC3 Promoter (EXOC3 Human)
SV40 universal enhancer

Use

Luciferase

Mutation

WT

Available Since

Nov. 5, 2025

Availability

Academic Institutions and Nonprofits only

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pGL4.10 EXOC3prom Chr5-LG4

Plasmid

#246712

Purpose

To investigate the influence of an LG4 enhancer (chr5 LG4) on EXOC3 promoter activity (measured by luciferase expression)

Depositor

Glen Borchert

Article

DeMeis et al Nucleic Acids Res. 2025 Jan 11;53(2):gka

Inserts

EXOC3 Promoter (EXOC3 Human)
chr5 LG4 enhancer

Use

Luciferase

Mutation

WT

Available Since

Nov. 5, 2025

Availability

Academic Institutions and Nonprofits only

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TRE-dCas9(sa)-VP64-AAV

Plasmid

#213035

Purpose

dCas9-VP64 expressed under control of TRE

Depositor

Nadav Ahituv

Article

Nguyen et al Nat Biotechnol. 2025 Feb 4:10.1038/s4158

Insert

dCas9

Use

AAV and CRISPR

Tags

NLS and NLS-VP64

Promoter

TRE, miniCMV

Available Since

Oct. 1, 2025

Availability

Academic Institutions and Nonprofits only

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TOPO-EXOC3 (-1557 to-1046)

Plasmid

#226446

Purpose

For subcloning of human EXOC3 promoter (base pairs -1557 to-1046) or for assays using M13 phage

Depositor

Glen Borchert

Article

DeMeis et al Nucleic Acids Res. 2025 Jan 11;53(2):gka

Insert

EXOC3 (-1557 to-1046) (EXOC3 Human)

Use

Cloning vector

Mutation

No

Available Since

Sept. 15, 2025

Availability

Academic Institutions and Nonprofits only

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TOPO-EXOC3 (-2455 to -1951)

Plasmid

#226441

Purpose

For subcloning of human EXOC3 promoter (base pairs -2455 to -1951) or for assays using M13 phage

Depositor

Glen Borchert

Article

DeMeis et al Nucleic Acids Res. 2025 Jan 11;53(2):gka

Insert

EXOC3 (-2455 to -1951) (EXOC3 Human)

Use

Cloning vector

Mutation

No

Available Since

July 28, 2025

Availability

Academic Institutions and Nonprofits only

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TOPO-EXOC3 (-1592 to -1046)

Plasmid

#226444

Purpose

For subcloning of human EXOC3 promoter (base pairs -1592 to -1046) or for assays using M13 phage

Depositor

Glen Borchert

Article

DeMeis et al Nucleic Acids Res. 2025 Jan 11;53(2):gka

Insert

EXOC3 (-1592 to -1046) (EXOC3 Human)

Use

Cloning vector

Mutation

No

Available Since

July 14, 2025

Availability

Academic Institutions and Nonprofits only

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TOPO-EXOC3 (-1591 to -1009)

Plasmid

#226443

Purpose

For subcloning of human EXOC3 promoter (base pairs -1591 to -1009) or for assays using M13 phage

Depositor

Glen Borchert

Article

DeMeis et al Nucleic Acids Res. 2025 Jan 11;53(2):gka

Insert

EXOC3 (-1591 to -1009) (EXOC3 Human)

Use

Cloning vector

Mutation

No

Available Since

July 14, 2025

Availability

Academic Institutions and Nonprofits only

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TOPO-EXOC3 (-1701 to -1594)

Plasmid

#226442

Purpose

For subcloning of human EXOC3 promoter (base pairs -1701 to -1594) or for assays using M13 phage

Depositor

Glen Borchert

Article

DeMeis et al Nucleic Acids Res. 2025 Jan 11;53(2):gka

Insert

EXOC3 (-1701 to -1594) (EXOC3 Human)

Use

Cloning vector

Mutation

No

Available Since

July 14, 2025

Availability

Academic Institutions and Nonprofits only

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TOPO-EXOC3 (-1592 to -1444)

Plasmid

#226445

Purpose

For subcloning of human EXOC3 promoter (base pairs -1592 to -1444) or for assays using M13 phage

Depositor

Glen Borchert

Article

DeMeis et al Nucleic Acids Res. 2025 Jan 11;53(2):gka

Insert

EXOC3 (-1592 to -1444) (EXOC3 Human)

Use

Cloning vector

Mutation

No

Available Since

July 11, 2025

Availability

Academic Institutions and Nonprofits only

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TOPO-EXOC3 (-1557 to-1444)

Plasmid

#226447

Purpose

For subcloning of human EXOC3 promoter (base pairs -1557 to-1444) or for assays using M13 phage

Depositor

Glen Borchert

Article

DeMeis et al Nucleic Acids Res. 2025 Jan 11;53(2):gka

Insert

EXOC3 (-1557 to-1444) (EXOC3 Human)

Use

Cloning vector

Mutation

No

Available Since

July 11, 2025

Availability

Academic Institutions and Nonprofits only

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pCAG-SpCas9-P2A-EGFP (MSP2582)

Plasmid

#223067

Purpose

pCAG human codon optimized wild-type SpCas9 expression plasmid with C-terminal NLS(SV40)-3xFLAG-P2A-EGFP

Depositor

Benjamin Kleinstiver

Article

Silverstein et al Nature. 2025 Apr 22. doi: 10.1038/s41586

Insert

human codon optimized SpCas9-P2A-EGFP

Use

CRISPR

Tags

NLS(SV40)-3xFLAG-P2A-EGFP

Expression

Mammalian

Promoter

CAG

Available Since

April 23, 2025

Availability

Academic Institutions and Nonprofits only

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pAAV-CMV-FLEX-SaCas9-U6-sgKcnma1

Plasmid

#209199

Purpose

Mutagenesis of Kcnma1

Depositor

Larry Zweifel

Article

Juarez et al Sci Adv. 2023 Aug 11;9(32):eadg8869. doi

Insert

Kcnma1 (Kcnma1 Mouse)

Use

AAV, CRISPR, and Mouse Targeting

Promoter

CMV

Available Since

Jan. 3, 2024

Availability

Academic Institutions and Nonprofits only

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Ubiquiton Yeast Kit

Plasmid Kit

#1000000243

Purpose

The Ubiquiton system allows the inducible, linkage-specific polyubiquitylation of a protein of interest, accommodating for linear (M1-), K48-, and K63-linkage.

Depositor

Helle Ulrich

Available Since

May 31, 2024

Availability

Academic Institutions and Nonprofits only
pAAV-MP-84-spCas9-U6-gRNA

Plasmid

#206935

Purpose

Expression of spCas9 endonuclease and gRNA in an AAV vector allowing packaging of viral genome smaller than 5 kb.

Depositor

Markus Grompe

Insert

spCas9

Use

AAV

Tags

SV40 NLS

Expression

Mammalian

Promoter

MP-84

Available Since

Sept. 14, 2023

Availability

Academic Institutions and Nonprofits only

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HaloTag-LacI-KRAB

Plasmid

#232638

Purpose

lac repressor (LacI) which binds lacO sites; labeled with HaloTag and coupled with Krüppel-associated box (KRAB) repressor

Depositor

Karsten Rippe

Insert

HaloTag-LacI-KRAB

Tags

NLS

Expression

Mammalian

Mutation

none

Promoter

CMV

Available Since

Feb. 27, 2025

Availability

Academic Institutions and Nonprofits only

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pPGK-GZF1-RR

Plasmid

#35092

Depositor

David Segal

Article

Bhakta et al Methods Mol Biol. 2010;649:3-30.

Insert

ZFN GZF1-Fok(RR)

Tags

HA and SV40 NLS

Expression

Mammalian

Mutation

contains the "RR" obligate heterodimer …

Promoter

PGK

Available Since

May 10, 2012

Availability

Academic Institutions and Nonprofits only

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pPGK-GZF3-DD

Plasmid

#35093

Depositor

David Segal

Article

Bhakta et al Methods Mol Biol. 2010;649:3-30.

Insert

ZFN GZF3-Fok(DD)

Tags

HA and SV40 NLS

Expression

Mammalian

Mutation

contains the "DD" obligate heterodimer …

Promoter

PGK

Available Since

May 10, 2012

Availability

Academic Institutions and Nonprofits only

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pCMV-ABE-P48R-UGI

Plasmid

#161817

Purpose

Expresses ABE-P48R-UGI in mammalian cells

Depositor

Sangsu Bae

Insert

bpNLS-TadA7.10(P48R)-32AA linker-hSpCas9n(D10A)-10AA linker-UGI-10AA linker-UGI-bpNLS-P2A-EGFP-NLS

Use

CRISPR

Expression

Mammalian

Mutation

D10A in S. pyogenes Cas9, TadA mutations describe…

Available Since

Jan. 4, 2021

Availability

Academic Institutions and Nonprofits only

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