167,785 results

1. pLX401-INK4A

   Plasmid

   #121919

   Purpose

   Doxycycline-inducible expression of p16-INK4A product of CDKN2A

   Depositor

   William Hahn

   Article

   Howard et al Cancer Res. 2019 Feb 12. pii: 0008-5472.

   Insert

   p16-INK4A (CDKN2A Human)
   

   Use

   Lentiviral

   Expression

   Mammalian

   Promoter

   TRE Tet ON

   Available Since

   April 3, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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2. pNP3254 [pNP2922 - ISCro4 Enhanced DBL (DBL3, WT) + ISCro4 Recombianse (WT]

   Plasmid

   #247257

   Purpose

   Express ISCro4 recombinase and bridge RNA

   Depositor

   Patrick Hsu

   Article

   Perry et al Science. 2025 Sep 25:eadz0276. doi: 10.1

   Insert

   pNP2922 - ISCro4 bRNA101-179 ins179(rc(101-111) (DBL3)
   

   Expression

   Mammalian

   Mutation

   ins179(rc(101-111)

   Available Since

   Oct. 23, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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3. pNP3386 [For use in genome insertion and off-target assessment]

   Plasmid

   #247258

   Purpose

   Example plasmid for bridge recombinase mediated insertion and off-target assessment with puromycin selection — must clone in UMI

   Depositor

   Patrick Hsu

   Article

   Perry et al Science. 2025 Sep 25:eadz0276. doi: 10.1

   Insert

   ISCro4 Recognition Site-UMI-Ef1a-PuroR-P2A-mCherry (Plasmid for Insertion Site Mapping [Example, Clone in Sequence + UMI])
   

   Expression

   Mammalian

   Available Since

   Oct. 23, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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4. pvPE-V2

   Plasmid

   #240286

   Purpose

   Encodes second generation porcine endogenous retrovirus-derived prime editing (pvPE) system into mammalian cells for gene editing.

   Depositor

   Lusheng Huang

   Article

   Liu et al Trends Biotechnol. 2025 Aug 30:S0167-779

   Insert

   pvPE-V2
   

   Use

   CRISPR

   Tags

   SV40 NLS

   Expression

   Mammalian

   Promoter

   CMV

   Available Since

   Oct. 8, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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5. pvPE-V3

   Plasmid

   #240287

   Purpose

   Encodes third generation porcine endogenous retrovirus-derived prime editing (pvPE) system into mammalian cells for gene editing.

   Depositor

   Lusheng Huang

   Article

   Liu et al Trends Biotechnol. 2025 Aug 30:S0167-779

   Insert

   pvPE-V3
   

   Use

   CRISPR

   Tags

   SV40 NLS

   Expression

   Mammalian

   Promoter

   CMV

   Available Since

   Oct. 8, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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6. NPY EGFP

   Plasmid

   #245034

   Purpose

   Secretory granule marker for endocrine cells

   Depositor

   Thomas Martin

   Insert

   NPY (NPY Human)
   

   Tags

   EGFP

   Expression

   Mammalian

   Available Since

   Sept. 30, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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7. NanoLuc-BAZ2A Fusion Vector

   Plasmid

   #238659

   Purpose

   Express NanoLuc-BAZ2A Fusion Protein in Mammalian Cells under a CMV promoter

   Depositor

   Promega Corporation

   Has Service

   DNA

   Insert

   BAZ2A (BAZ2A Human)
   

   Tags

   NanoLuc (R)

   Expression

   Mammalian

   Mutation

   None

   Promoter

   CMV

   Available Since

   Sept. 14, 2025

   Availability

   Industry, Academic Institutions, and Nonprofits

   

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8. NanoLuc-EP300 Fusion Vector

   Plasmid

   #238648

   Purpose

   Express NanoLuc-EP300 Fusion Protein in Mammalian Cells under a CMV promoter

   Depositor

   Promega Corporation

   Has Service

   DNA

   Insert

   EP300 (EP300 Human)
   

   Tags

   NanoLuc (R)

   Expression

   Mammalian

   Mutation

   None

   Promoter

   CMV

   Available Since

   Sept. 14, 2025

   Availability

   Industry, Academic Institutions, and Nonprofits

   

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9. pcDNA-DEST47-SIRT1

   Plasmid

   #242131

   Purpose

   Expression in mammalian cells

   Depositor

   J. Carl Barrett, Izumi Horikawa

   Article

   Michishita et al Mol Biol Cell. 2005 Oct;16(10):4623-35.

   Insert

   SIRT1 (SIRT1 Human)
   

   Tags

   Cycle 3 GFP

   Expression

   Mammalian

   Promoter

   CMV

   Available Since

   Aug. 19, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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10. pLenti-CMV-MFSD6-mNeon-Puro

    Plasmid

    #239955

    Purpose

    Lentiviral vector to generate mNeon-tagged MFSD6 stable expressing cell line under CMV promoter

    Depositor

    Jan Carette

    Article

    Varanese et al Nature. 2025 Mar 25. doi: 10.1038/s41586

    Insert

    MFSD6-mNeon
    

    Use

    Lentiviral

    Tags

    mNeon

    Expression

    Mammalian

    Available Since

    July 24, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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11. pLenti-CMV-MFSD6-Puro

    Plasmid

    #239953

    Purpose

    Lentiviral vector to generate MFSD6 stable expressing cell line under CMV promoter

    Depositor

    Jan Carette

    Article

    Varanese et al Nature. 2025 Mar 25. doi: 10.1038/s41586

    Insert

    MFSD6
    

    Use

    Lentiviral

    Tags

    myc-flag

    Expression

    Mammalian

    Available Since

    July 24, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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12. pLenti-CMV-MFSD8-Puro

    Plasmid

    #239954

    Purpose

    Lentiviral vector to generate MFSD8 stable expressing cell line under CMV promoter

    Depositor

    Jan Carette

    Article

    Varanese et al Nature. 2025 Mar 25. doi: 10.1038/s41586

    Insert

    MFSD8
    

    Use

    Lentiviral

    Tags

    myc-flag

    Expression

    Mammalian

    Available Since

    July 14, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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13. pAAV-CMV-intron-hfCas13d-pA/EF1a-mCherry-WPRE-pa

    Plasmid

    #233034

    Purpose

    To Express HA tagged hfCas13d the CMV promoter. Also encodes a mCherry gene outside of the viral genome

    Depositor

    Jonathan Ploski

    Article

    Back et al Mol Ther Methods Clin Dev. 2025 Aug 20;3

    Insert

    hfCas13d and mCherry
    

    Use

    AAV

    Tags

    mCherry

    Available Since

    March 4, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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14. pMR-A-3-Sasg

    Plasmid

    #214349

    Purpose

    Expresses T7-RNAP, and cloning backbone for sgRNA

    Depositor

    Yongming Wang

    Article

    Qi et al Nat Chem Biol. 2023 Dec 5. doi: 10.1038/

    Insert

    T7-RNAP
    

    Expression

    Bacterial

    Available Since

    Feb. 27, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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15. pGEX6P1-NEDD4L_HECT

    Plasmid

    #187719

    Purpose

    Express GST-tagged NEDD4L HECT domain in bacterial cells

    Depositor

    Sandra Gabelli

    Article

    Wright et al J Biol Chem. 2024 Mar;300(3):105715. doi

    Insert

    NEDD4L residues 594-975 (NEDD4L Human)
    

    Tags

    GST-HRV 3C site

    Expression

    Bacterial

    Mutation

    deletion of residues 1-593

    Available Since

    Oct. 24, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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16. MP6-SlugABEN-738

    Plasmid

    #214348

    Purpose

    Expresses N-terminus of ABE, and untargeted Bacterial Mutagenesis

    Depositor

    Yongming Wang

    Article

    Qi et al Nat Chem Biol. 2023 Dec 5. doi: 10.1038/

    Insert

    dnaQ926 dam seqA emrR ugi CDA1 and N-terminus of ABE
    

    Expression

    Bacterial

    Available Since

    April 5, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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17. pBT120a17-sg-del

    Plasmid

    #214347

    Purpose

    Expresses pIII

    Depositor

    Yongming Wang

    Article

    Qi et al Nat Chem Biol. 2023 Dec 5. doi: 10.1038/

    Insert

    gIII-xLuxAB
    

    Expression

    Bacterial

    Available Since

    Feb. 29, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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18. mU6-CR1-CRISPRiv2_hU6-CR3-NT-ctrl-guide_EF1a-PuroR-T2A-BFP

    Pooled Library

    #197348

    Purpose

    To allow for genome-wide genetic modifier screening, the library has a second fixed non-targeting control guide.

    Depositor

    Rebecca Voorhees, Jonathan Weissman

    Article

    Guna et al BMC Genomics. 2023 Oct 30;24(1):651. doi

    Species

    Homo sapiens

    Use

    Lentiviral

    Available Since

    May 25, 2023

    Availability

    Academic Institutions and Nonprofits only

19. pD649-HAsp-DLL4-COMP5AP-AviTag-9xHis

    Plasmid

    #157453

    Purpose

    Mammalian expression of cell-surface protein extracellular domain fused to COMP5AP-AviTag-9xHis. Protein is secreted from cells.

    Depositor

    Chris Garcia

    Article

    Wojtowicz et al Cell. 2020 Aug 20;182(4):1027-1043.e17.

    Insert

    DLL4 (DLL4 Human)
    

    Tags

    COMP5AP-AviTag-9xHis

    Expression

    Mammalian

    Promoter

    CMV/SP6

    Available Since

    March 8, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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20. pAAV-CMV-intron-hfCas13d-pA

    Plasmid

    #195864

    Purpose

    To express hfCas13d

    Depositor

    Jonathan Ploski

    Article

    Back et al Mol Ther Methods Clin Dev. 2025 Aug 20;3

    Insert

    high fidelity (hf) version of CasRx (hfCas13d)
    

    Use

    AAV

    Mutation

    Yes: GTGGAATACATTACCAACGTGGTGTACGTG

    Promoter

    CMV

    Available Since

    Jan. 30, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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