We narrowed to 90,020 results for: Mal;

1. pLX304-BCL-XL-F97W

   Plasmid

   #203572

   Purpose

   Expresses V5-tagged BCL-XL with partial drug resistance to A-1331852 in mammalian cells.

   Depositor

   Abhishek Chakraborty

   Article

   Grubb et al Clin Cancer Res. 2022 Nov 1;28(21):4689-

   Insert

   BCL2L1 (BCL2L1 Human)
   

   Use

   Lentiviral

   Tags

   V5-tagged

   Expression

   Mammalian

   Mutation

   Changed Phenylalanine 97 to Tryptophan for partia…

   Promoter

   CMV

   Available Since

   Dec. 6, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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2. pPBpuro-miRFP703-eDHFR(69K6)-cRaf

   Plasmid

   #209919

   Purpose

   Mammalian expression of cRaf fused to miRFP703-eDHFR(69K6)

   Depositor

   Michiyuki Matsuda

   Article

   Deguchi et al Cell Rep. 2024 Nov 14;43(11):114986. doi

   Insert

   miRFP703-eDHFR(69K6)-cRaf (RAF1 Human)
   

   Expression

   Mammalian

   Available Since

   Nov. 18, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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3. pPBbleo-miRFP703-eDHFR(69K6)-cRaf

   Plasmid

   #209920

   Purpose

   Mammalian expression of cRaf fused to miRFP703-eDHFR(69K6)

   Depositor

   Michiyuki Matsuda

   Article

   Deguchi et al Cell Rep. 2024 Nov 14;43(11):114986. doi

   Insert

   miRFP703-eDHFR(69K6)-cRaf (RAF1 Human)
   

   Expression

   Mammalian

   Available Since

   Nov. 18, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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4. pPBbsr2-miRFP703-eDHFR(69K6)-cRaf

   Plasmid

   #209921

   Purpose

   Mammalian expression of cRaf fused to miRFP703-eDHFR(69K6)

   Depositor

   Michiyuki Matsuda

   Article

   Deguchi et al Cell Rep. 2024 Nov 14;43(11):114986. doi

   Insert

   miRFP703-eDHFR(69K6)-cRaf (RAF1 Human)
   

   Expression

   Mammalian

   Available Since

   Nov. 18, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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5. pLX304-BCL-XL-499R

   Plasmid

   #203574

   Purpose

   Expresses V5-tagged BCL-XL with resistance to shRNA (TRCN0000033499) in mammalian cells.

   Depositor

   Abhishek Chakraborty

   Article

   Grubb et al Clin Cancer Res. 2022 Nov 1;28(21):4689-

   Insert

   BCL2L1 (BCL2L1 Human)
   

   Use

   Lentiviral

   Tags

   V5- tagged

   Expression

   Mammalian

   Mutation

   silent point mutations introduced to make it resi…

   Promoter

   CMV

   Available Since

   Feb. 22, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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6. pDEST-Myc-FBW7 Delta D-Domain

   Plasmid

   #197453

   Purpose

   The plasmid expresses D-domain deleted version of Myc-tagged FBW7 human isoform 1. Used for mammalian overexpression and detection by western blotting.

   Depositor

   Omar Khan

   Article

   Khan et al Nat Commun. 2021 Apr 6;12(1):2043. doi:

   Insert

   FBW7 (FBXW7 Human)
   

   Tags

   Myc

   Expression

   Mammalian

   Mutation

   FBW& dimerization domain deleted.

   Promoter

   CMV

   Available Since

   June 1, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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7. pDEST-Myc-FBW7K404/412/R

   Plasmid

   #200716

   Purpose

   The plasmid expresses Myc-tagged FBW7 human isoform 1 with Lys404 & 412 to Arg mutation. Used for mammalian overexpression and detection by western blotting.

   Depositor

   Omar Khan

   Article

   Khan et al Nat Commun. 2021 Apr 6;12(1):2043. doi:

   Insert

   FBW7 (FBXW7 Human)
   

   Tags

   Myc

   Expression

   Mammalian

   Mutation

   FBW7 K404 and K412 mutated to Alanines.

   Promoter

   CMV

   Available Since

   June 1, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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8. pBactin-Akna-mOrange2

   Plasmid

   #196865

   Purpose

   Expression of the centrosomal protein Akna fused to mOrange2

   Depositor

   Frank Bradke

   Article

   Vinopal et al Neuron. 2023 Apr 19;111(8):1241-1263.e16

   Insert

   Akna-mOrange2 (Akna Mouse)
   

   Expression

   Mammalian

   Promoter

   Chicken bactin (plus Chicken bactin intron)

   Available Since

   May 16, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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9. pLD-puro-Cn-VA-NHEJ1-S262E/S263E

   Plasmid

   #141342

   Purpose

   Lentiviral vector for expression of human NHEJ1-S262E/S263E in mammalian cells

   Depositor

   Mohan Babu

   Article

   Jessulat et al Nucleic Acids Res. 2021 Jul 9. pii: 6318

   Insert

   NHEJ1-S262E/S263E (NHEJ1 Human)
   

   Use

   Lentiviral

   Tags

   VA tag (3XFLAG-2XTEV-6XHis-2XStrep-Beacon)

   Expression

   Mammalian

   Mutation

   S262E/S263E

   Promoter

   CMV

   Available Since

   Aug. 2, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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10. pLD-puro-Cn-VA-NHEJ1-S262A/S263A

    Plasmid

    #141343

    Purpose

    Lentiviral vector for expression of human NHEJ1-S262A/S263A in mammalian cells

    Depositor

    Mohan Babu

    Article

    Jessulat et al Nucleic Acids Res. 2021 Jul 9. pii: 6318

    Insert

    NHEJ1-S262A/S263A (NHEJ1 Human)
    

    Use

    Lentiviral

    Tags

    VA tag (3XFLAG-2XTEV-6XHis-2XStrep-Beacon)

    Expression

    Mammalian

    Mutation

    S262A/S263A

    Promoter

    CMV

    Available Since

    Aug. 2, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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11. pcDNA3. Flag-CSL Q307R

    Plasmid

    #167009

    Purpose

    Mammalian expression of CSL Q307R

    Depositor

    Gian-Paolo Dotto

    Article

    Bottoni et al Nat Commun. 2019 Aug 29;10(1):3884. doi:

    Insert

    CSL (RBPJ Human)
    

    Tags

    FLAG

    Expression

    Mammalian

    Mutation

    Q307R

    Promoter

    CMV

    Available Since

    April 23, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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12. pcDNA3. Flag-CSL A258R

    Plasmid

    #167008

    Purpose

    Mammalian expression of CSL A258R

    Depositor

    Gian-Paolo Dotto

    Article

    Bottoni et al Nat Commun. 2019 Aug 29;10(1):3884. doi:

    Insert

    CSL (RBPJ Human)
    

    Tags

    FLAG

    Expression

    Mammalian

    Mutation

    A258R

    Promoter

    CMV

    Available Since

    April 23, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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13. pcDNA3. Flag-CSL V237A

    Plasmid

    #167007

    Purpose

    Mammalian expression of CSL V237A

    Depositor

    Gian-Paolo Dotto

    Article

    Bottoni et al Nat Commun. 2019 Aug 29;10(1):3884. doi:

    Insert

    CSL (RBPJ Human)
    

    Tags

    FLAG

    Expression

    Mammalian

    Mutation

    V237A

    Promoter

    CMV

    Available Since

    April 23, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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14. pcDNA3. Flag-CSL F235R

    Plasmid

    #167006

    Purpose

    Mammalian expression of CSL F235R

    Depositor

    Gian-Paolo Dotto

    Article

    Bottoni et al Nat Commun. 2019 Aug 29;10(1):3884. doi:

    Insert

    CSL (RBPJ Human)
    

    Tags

    FLAG

    Expression

    Mammalian

    Mutation

    F235

    Promoter

    CMV

    Available Since

    April 23, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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15. DHC1-mIAA7 Neo

    Plasmid

    #140543

    Purpose

    DHC1 tagging with mIAA7

    Depositor

    Masato Kanemaki

    Article

    Yesbolatova et al Nat Commun. 2020 Nov 11;11(1):5701. doi:

    Insert

    DHC1 (DYNC1H1 Human)
    

    Use

    CRISPR

    Expression

    Mammalian

    Available Since

    Nov. 12, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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16. pLENTI_Hu_ECT2(T327D)

    Plasmid

    #136332

    Purpose

    Lentiviral expression of human ECT2_T327D

    Depositor

    Guillermo de Cárcer, Marcos Malumbres

    Article

    de Carcer et al Nat Med. 2017 Aug;23(8):964-974. doi: 10

    Insert

    ECT2 (ECT2 Human)
    

    Use

    Lentiviral

    Expression

    Mammalian

    Mutation

    T327D

    Available Since

    Aug. 10, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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17. pMCh-1540

    Plasmid

    #82433

    Purpose

    Plasmid for expression of GST-tagged human-Nematostella GW182 11W11A chimera in mammalian cells

    Depositor

    Marina Chekulaeva

    Article

    Mauri et al Nucleic Acids Res. 2016 Sep 6. pii: gkw7

    Insert

    hs-nvGW182 11W11A chimera
    

    Tags

    GST

    Expression

    Mammalian

    Mutation

    aa 1-1169 of siRNA resistant hsTNRC6A (Q8NDV7-2) …

    Promoter

    EF1A

    Available Since

    Sept. 20, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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18. Tet-pLKO-puro-Scrambled

    Plasmid

    #47541

    Purpose

    Tet inducible scrambled shRNA.

    Depositor

    Charles Rudin

    Article

    Rudin et al Nat Genet. 2012 Oct;44(10):1111-6. doi:

    Insert

    Scrambled shRNA
    

    Use

    Lentiviral and RNAi

    Expression

    Mammalian

    Promoter

    H1

    Available Since

    April 28, 2015

    Availability

    Academic Institutions and Nonprofits only

    

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19. pcDNA3.1(+)_U6 tRNAPyl_CMV NESPylRS(AF)_IRES_eRF1(E55D)-HA

    Plasmid

    #182653

    Purpose

    Encodes codon-optimized AF mutant of M. mazei pyrrolysine (Pyl) tRNA synthetase fused to a nuclear export signal (NESPylRSAF),tRNACUAPyl & eRF1E55D used for amber codon suppression in mammalian cells

    Depositor

    Ivana Nikić-Spiegel

    Article

    Arsic et al Nat Commun. 2022 Jan 14;13(1):314. doi:

    Inserts

    codon-optimized Y306A/Y384F (AF) double mutant of Methanosarcina mazei-derived pyrrolysine (Pyl) tRNA synthetase
    PylT
    mutant eukaryotic release factor 1
    

    Tags

    HA tag and nuclear export signal (NES)

    Expression

    Mammalian

    Mutation

    E55D and Y306A/Y384F (AF) double mutant of Methan…

    Promoter

    CMV and U6

    Available Since

    June 16, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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20. pCBh-NLS_hfCas13d(RfxCas13d_N2V8)_HA_NLS-pA-U6-DR-BpiI-BpiI-pSV40-EGFP-pA-pSV40-mCherry-pA

    Plasmid

    #190034

    Purpose

    vector for encoding a human codon-optimized High-fidelity RfxCas13d (hfCas13d) driven by CBh promoter, guide RNAs compatible with RfxCas13d driven by hU6, EGFP and mCherry driven by SV40 promoters

    Depositor

    Huawei Tong

    Article

    Tong et al Nat Biotechnol. 2022 Aug 11. pii: 10.103

    Insert

    humanized hfCas13d
    

    Expression

    Mammalian

    Mutation

    A134V,A140V,A141V,A143V

    Promoter

    CBh, SV40, hU6

    Available Since

    Sept. 12, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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