168,956 results

1. pAAVLINK-EF1alpha-HA-5'-UNC13A

   Plasmid

   #244344

   Purpose

   5' AAVLINK plasmid for UNC13A expression

   Depositor

   Zhonghua Lu

   Insert

   UNC13A (UNC13A Human)
   

   Use

   AAV

   Tags

   HA

   Promoter

   EF1alpha

   Available Since

   Nov. 10, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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2. pAG mIgG2a Empty

   Plasmid

   #242953

   Purpose

   Expresses mouse IgG2a heavy chain constant region. Users can clone in their desired heavy chain variable region for mammalian expression; to be used with pAG mKappa Empty light chain (Plasmid 242954)

   Depositor

   Meghan Rego, Addgene Research Program

   Type

   Empty backbone

   Tags

   Mouse IgG2a

   Expression

   Mammalian

   Promoter

   CMV

   Available Since

   Nov. 6, 2025

   Availability

   Industry, Academic Institutions, and Nonprofits

   

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3. pAG mKappa Empty

   Plasmid

   #242954

   Purpose

   Expresses mouse kappa light chain constant region. Users can clone in their desired light chain variable region for mammalian expression; to be used with pAG mIgG2a Empty heavy chain (Plasmid 242953)

   Depositor

   Meghan Rego, Addgene Research Program

   Type

   Empty backbone

   Expression

   Mammalian

   Promoter

   CMV

   Available Since

   Nov. 6, 2025

   Availability

   Industry, Academic Institutions, and Nonprofits

   

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4. pLminP_Luc2P_RE56

   Plasmid

   #247034

   Purpose

   Glucocorticoid Receptor pathway reporter; lentiviral expression of NR3C1 (GR) DNA response element cloned 5' to firefly luciferase. Coexpresses EmGFP to monitor lentiviral transduction.

   Depositor

   Ramnik Xavier

   Article

   O'Connell et al Cell Syst. 2016 May 25;2(5):323-34. doi:

   Insert

   Firefly luciferase
   

   Use

   Lentiviral

   Promoter

   NR3C1 (GR)

   Available Since

   Nov. 6, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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5. pCAG-GFP1 POD-nAb-WPRE

   Plasmid

   #244973

   Purpose

   Expresses a fusion protein of a nanobody against GFP and peroxidase (POD) in mammalian cells

   Depositor

   Hiroyuki Hioki

   Article

   Yamauchi et al Commun Biol. 2025 Jun 18;8(1):903. doi:

   Insert

   GFP1 POD-nAb
   

   Available Since

   Oct. 20, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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6. pCAG-RFP6 POD-nAb-WPRE

   Plasmid

   #244974

   Purpose

   Expresses a fusion protein of a nanobody against RFP and peroxidase (POD) in mammalian cells

   Depositor

   Hiroyuki Hioki

   Article

   Yamauchi et al Commun Biol. 2025 Jun 18;8(1):903. doi:

   Insert

   RFP6 POD-nAb
   

   Available Since

   Oct. 20, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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7. pCAGGS-SGSM3[1-723]

   Plasmid

   #246258

   Purpose

   Rab5 GAP

   Depositor

   Ryohei Yasuda

   Article

   Wang et al Elife. 2025 Sep 23;13:RP103879. doi: 10.

   Insert

   Sgsm3[1-723] (Sgsm3 Rat)
   

   Expression

   Mammalian

   Promoter

   CAG

   Available Since

   Oct. 7, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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8. pT7-MLH1dn (mouse) for IVT

   Plasmid

   #246485

   Purpose

   Template for in vitro transcription of mouse MLH1dn

   Depositor

   David Liu

   Article

   Chen et al Cell. 2021 Oct 28;184(22):5635-5652.e29.

   Insert

   mouse MLH1dn (Mlh1 Mouse)
   

   Use

   Template for in vitro transcription

   Mutation

   deletion of residues 758-760

   Promoter

   T7

   Available Since

   Oct. 2, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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9. pCMV-MMLVgag-dCas9-KOX1

   Plasmid

   #240528

   Purpose

   Expresses MMLVgag–dCas9-KOX1 for producing RENDER-dCas9-KOX1

   Depositor

   James Nuñez

   Article

   Xu et al Nat Commun. 2025 Aug 26;16(1):7948. doi:

   Insert

   MMLVgag-dCas9-KOX1
   

   Expression

   Mammalian

   Available Since

   Aug. 19, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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10. pGEX-4T-3-GST-Tev-Af1521-myc

    Plasmid

    #196239

    Purpose

    N-terminal GST fusion of Af1521(WT) with a TEV protease site located between the GST tag and Af1521 and a myc tag on the C terminus

    Depositor

    Robert Sobol

    Article

    Al-Rahahleh et al DNA Repair (Amst). 2025 Jun;150:103845.

    Insert

    N-terminal GST fusion of Af1521(WT) with a TEV protease site between GST and Af1521 encoding a C-terminal myc tag
    

    Tags

    GST tag and myc tag

    Expression

    Bacterial

    Available Since

    Aug. 8, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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11. pRK5_mEGFP-NUP98-HOXA9-KS

    Plasmid

    #237673

    Purpose

    For overexpression of mEGFP-NUP98-HOXA9-KS

    Depositor

    Denes Hnisz

    Article

    Zhang et al Nature. 2025 Jun 4. doi: 10.1038/s41586-

    Insert

    NUP98-HOXA9-KS (NUP98, HOXA9 Human)
    

    Tags

    mEGFP

    Expression

    Mammalian

    Available Since

    May 6, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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12. pLVX-TetOne-Puro-LbNOX-Flag

    Plasmid

    #234984

    Purpose

    Expresses LbNOX in human cell lines

    Depositor

    Denis Titov

    Article

    Choe et al Cell Chem Biol. 2025 Apr 17;32(4):620-63

    Insert

    LbNOX
    

    Use

    Lentiviral

    Tags

    Flag

    Expression

    Mammalian

    Available Since

    April 22, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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13. pTR01F/hFGFR4-V5

    Plasmid

    #236017

    Purpose

    for PiggyBac mediated integration and stable expression of hFGFR4 protein

    Depositor

    Pavel Krejčí

    Article

    Zlinska et al Mol Ther Nucleic Acids. 2024 Nov 28;36(1

    Insert

    human FGFR4 (FGFR4 Human)
    

    Tags

    V5/His

    Expression

    Mammalian

    Promoter

    truncated CMV promoter

    Available Since

    April 22, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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14. pPYRMandi-ABI

    Plasmid

    #233649

    Purpose

    Cellular colocalization assay (PYRMandi/ABI) for the CIP Mandi (mandipropamid)

    Depositor

    Richard Wombacher

    Article

    Poschko et al ACS Chem Biol. 2025 Jan 27. doi: 10.1021

    Insert

    TOMM20-mCherry-PYRMandi-P2A-eGFP-ABI
    

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    April 9, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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15. mNG-PH-CYTH3-2G

    Plasmid

    #233261

    Purpose

    Expression of mNeonGreen-tagged PIP3 reporter

    Depositor

    David Bryant

    Article

    Nikolatou et al EMBO J. 2023 Sep 18;42(18):e113987. doi:

    Insert

    PIP3 reporter
    

    Use

    Lentiviral

    Available Since

    March 17, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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16. TFORF2480

    Plasmid

    #142102

    Purpose

    Lentiviral vector for overexpressing transcription factor ORFs with unique 24-bp barcodes. Barcodes facilitate identification of transcription factors in pooled screens.

    Depositor

    Feng Zhang

    Article

    Joung et al Cell. 2023 Jan 5;186(1):209-229.e26. doi

    Insert

    MXD4 (MXD4 Human)
    

    Use

    Lentiviral

    Expression

    Mammalian

    Promoter

    EF1a

    Available Since

    Dec. 2, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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17. pcDNA3.1(-).TagRFP.T-2A-Tau2N4R-WPRE

    Plasmid

    #226380

    Purpose

    Expresses tau propagation ORF with no V5 tag on WT 2N4R tau

    Depositor

    Bradley Hyman

    Article

    Dickson et al J Neuropathol Exp Neurol. 2025 Jun 1;84(

    Insert

    Tau2N4R (MAPT synthetic, Human)
    

    Tags

    TagRFP.T-2A

    Expression

    Mammalian

    Available Since

    Nov. 14, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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18. pET28.His.3C.86b.Tau2N4R

    Plasmid

    #226399

    Purpose

    Expresses his-tagged, 3C-cleavable, 86b (split luciferase fragment)-tagged WT 2N4R tau for recombinant protein production in bacteria

    Depositor

    Bradley Hyman

    Article

    Dickson et al J Neuropathol Exp Neurol. 2025 Jun 1;84(

    Insert

    Tau2N4R (MAPT synthetic, Human)
    

    Tags

    His.3C.86b

    Expression

    Bacterial

    Available Since

    Nov. 14, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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19. hSyn-GEM

    Plasmid

    #187648

    Purpose

    Expresses the rheological probe PfV-HaloTag-SNAP-tag (GEM-HaloTag-SNAP-tag) under control of human synapsin promoter.

    Depositor

    Erin O'Shea

    Article

    Wong et al Elife. 2024 Aug 15;13:e80622. doi: 10.75

    Insert

    PfV
    

    Use

    AAV

    Tags

    HaloTag and SNAP-tag

    Expression

    Mammalian

    Promoter

    Synapsin

    Available Since

    Oct. 23, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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20. pAAV-MCHpr-GCaMP6f

    Plasmid

    #221039

    Purpose

    Expresses GCaMP6f under the rat pro-melanin-concentrating hormone promoter

    Depositor

    Yanhua Huang

    Article

    Guo et al Biol Psychiatry. 2022 Dec 1;92(11):880-8

    Insert

    GCaMP6f
    

    Use

    AAV; Rat targeting

    Expression

    Mammalian

    Mutation

    A317E

    Promoter

    Rat MCH

    Available Since

    Aug. 14, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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