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Enter a sequence to perform a BLAST-based search of Addgene plasmid sequence databases.

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We narrowed to 36,359 results for: lat

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Showing: 10141 - 10160 of 36359 results

  1. pCAG-hHDAC4

    Plasmid
    #21096
    Depositor
    Connie Cepko
    Publication
    Chen et al Science. 2009 Jan 9. 323(5911):256-9.
    Has service
    50 µg Transfection-Ready DNA and 100 µg Transfection-Ready DNA
    Insert
    Histone Deacetylase 4 (HDAC4 Human)
    Expression
    Mammalian
    Mutation
    shRNA target sequence was mutated (mutated nucleo…
    Promoter
    CAG
    Available since
    May 5, 2009
    Availability
    Academic Institutions and Nonprofits only

  6. pCMV-dCas13-NES-eNAT10

    Plasmid
    #238299
    Purpose
    Expresses cytoplasmic version of the programmable RNA acetylation system.
    Depositor
    Won Do Heo
    Publication
    Yu et al Nat Chem Biol. 2025 Jun 2. doi: 10.1038/
    Has service
    50 µg Transfection-Ready DNA and 100 µg Transfection-Ready DNA
    Insert
    dPspCas13b fused to eNAT10 (NAT10 Human, Prevotella sp. P5-125)
    Use
    CRISPR
    Tags
    HIV NES (C terminal of dPspCas13b)
    Expression
    Mammalian
    Mutation
    H133A for catalytically inactive mutant, deletion…
    Available since
    June 9, 2025
    Availability
    Academic Institutions and Nonprofits only
    238299-plasmid-map-sequence-id-472414

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  7. xPERT-hA2q

    Plasmid
    #231063
    Purpose
    Circularly permuted CasRx platform fused to human deaminase domain for A to I editing
    Depositor
    Meng How Tan
    Publication
    Wang et al Nat Biotechnol. 2024 Oct 9. doi: 10.1038
    Has service
    50 µg Transfection-Ready DNA and 100 µg Transfection-Ready DNA
    Inserts
    dCas13d
    Human deaminase ADAR2dd (ADARB1 Ruminococcus flavefaciens XPD3002)
    Use
    CRISPR
    Expression
    Mammalian
    Mutation
    H460D, E488Q, only the deaminase domain (aa 276-7…
    Promoter
    CMV
    Available since
    Jan. 30, 2025
    Availability
    Academic Institutions and Nonprofits only
    231063-plasmid-map-sequence-id-459741

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  10. pcDNA3.1(+)-FluoSTEP-ICUE

    Plasmid
    #181845
    Purpose
    Genetically encoded FRET-based sensor for monitoring cAMP dynamics near a protein of interest. Must pair with GFP11-tagged POI to reconstitute donor fluorescence.
    Depositor
    Jin Zhang
    Publication
    Zhang et al Cell. 2020 Sep 17;182(6):1531-1544.e15.
    Has service
    50 µg Transfection-Ready DNA and 100 µg Transfection-Ready DNA
    Insert
    FluoSTEP-ICUE (RAPGEF3 Human)
    Tags
    mRuby2 and sfGFP(1-10)
    Expression
    Mammalian
    Promoter
    CMV
    Available since
    July 6, 2022
    Availability
    Academic Institutions and Nonprofits only
    Cited by
    181845-plasmid-map-sequence-id-364061

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  12. pLenti-CD74-ROS1 G2032R

    Plasmid
    #183814
    Purpose
    Express CD74-ROS1 fusion (C6;R34) harboring ROS1 G2032R mutation in mammalian cells
    Depositor
    Aaron Hata
    Publication
    Lin et al Clin Cancer Res. 2021 May 15;27(10):2899
    Inserts
    ROS Proto-Oncogene 1, Receptor Tyrosine Kinase (ROS1 Human)
    CD74 molecule (CD74 Human)
    Use
    Retroviral
    Tags
    The fusion protein of CD74 exon 1-6 and ROS1 exon…
    Expression
    Mammalian
    Mutation
    G2032R
    Promoter
    CMV
    Available since
    April 27, 2022
    Availability
    Academic Institutions and Nonprofits only
    183814-plasmid-map-sequence-id-360438

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  14. Flag-neo-PP1-Alpha-H248K

    Plasmid
    #171268
    Purpose
    Mammalian expression of 3x-Flag-tagged human PP1 alpha catalytic subunit H248K mutant that loses enzymatic activity
    Depositor
    Steven Balk
    Publication
    Liu et al Oncotarget. 2016 Jan 12;7(2):1754-64. do
    Insert
    3x-Flag-tagged human PP1 alpha catalytic subunit H248K mutant (PPP1CA Human)
    Tags
    Flag
    Expression
    Mammalian
    Mutation
    PPP1CA-His248Lys (H248K)
    Promoter
    CMV
    Available since
    June 28, 2021
    Availability
    Academic Institutions and Nonprofits only
    171268-plasmid-map-sequence-id-336095

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  15. pCC_06 - hU6-BsmBI-sgRNA(E+F)-barcode-EFS-dCas9NG-NLS-VPR-2A-Puro-WPRE

    Plasmid
    #139091
    Purpose
    Expresses human codon-optimized inactive SpCas9-NG fused to a transcriptional activator VPR in mammalian cells. For cloning of sgRNAs using BsmBI. Contains a barcode downstream of sgRNA cassette.
    Depositor
    Neville Sanjana
    Publication
    Legut et al Cell Rep. 2020 Mar 3;30(9):2859-2868.e5.
    Insert
    dSpCas9-NG-VPR
    Use
    CRISPR and Lentiviral
    Expression
    Mammalian
    Mutation
    D10A, H840A, L1111R, D1135V,G1218R, E1219F, A1322…
    Available since
    March 6, 2020
    Availability
    Academic Institutions and Nonprofits only
    139091-plasmid-map-sequence-id-273888

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  16. Dom neg CstF64

    Plasmid
    #127250
    Purpose
    Expresses the Dominant Negative CstF64 in mammalian cells; DN blocks polyadenylation
    Depositor
    Christine Milcarek
    Publication
    Martincic et al Nat Immunol. 2009 Oct;10(10):1102-9. doi
    Has service
    50 µg Transfection-Ready DNA and 100 µg Transfection-Ready DNA
    Insert
    CstF64 delta 282 (CSTF2 Human)
    Use
    Other
    Expression
    Mammalian
    Mutation
    insert @SanD1:GTCCAGGCGCCTACCCATACGACGTCCCAGACTAC…
    Promoter
    pEF1a
    Available since
    July 15, 2019
    Availability
    Academic Institutions and Nonprofits only
    127250-plasmid-map-sequence-id-250029

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  17. pCSD_2XNLS-SpCas9WT-NLS-3XHA-2XNLS-NmdCas9-NLS

    Plasmid
    #107327
    Purpose
    Expresses SpCas9 fused to dNmCas9 in mammalian cells
    Depositor
    Scot Wolfe
    Publication
    Bolukbasi et al Nat Commun. 2018 Nov 19;9(1):4856. doi:
    Has service
    50 µg Transfection-Ready DNA and 100 µg Transfection-Ready DNA
    Insert
    SpCas9-NmCas9 fusion
    Use
    CRISPR
    Tags
    NLS
    Expression
    Mammalian
    Mutation
    SpCas9 is fused to nuclease dead NmCas9 (D16A, D5…
    Promoter
    CMV IE94
    Available since
    Nov. 15, 2018
    Availability
    Academic Institutions and Nonprofits only
    107327-plasmid-map-sequence-id-204775

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  18. pCMV iGluf

    Plasmid
    #105833
    Purpose
    Fast indicator for extracellular glutamate imaging
    Depositor
    Katalin Torok
    Publication
    Helassa et al Proc Natl Acad Sci U S A. 2018 May 7. pi
    Has service
    50 µg Transfection-Ready DNA and 100 µg Transfection-Ready DNA
    Insert
    iGluSnFR E25D variant
    Tags
    Myc and PDGFR
    Expression
    Mammalian
    Mutation
    Changed Glu 25 to Asp
    Promoter
    CMV
    Available since
    June 18, 2018
    Availability
    Academic Institutions and Nonprofits only
    105833-plasmid-map-sequence-id-211679

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Showing: 10141 - 10160 of 36359 results