167,948 results

1. pAAV-hSyn-IgK-R-eLACCO2.1-COBRA

   Plasmid

   #223349

   Purpose

   Biosensor for extracellular L-lactate

   Depositor

   Marie-Eve Paquet

   Article

   Kamijo et al Nat Commun. 2025 Oct 29;16(1):9531. doi:

   Insert

   eLACCO2.1
   

   Use

   AAV

   Tags

   GPI-COBL9 Anchor

   Available Since

   Sept. 11, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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2. pSLQ14566

   Plasmid

   #239272

   Purpose

   Expresses TRF1-PYL1 for recruiting RNA to the telomere via CRISPR-TO

   Depositor

   Stanley Qi

   Article

   Han et al Nature. 2025 Jul;643(8070):241-251. doi:

   Insert

   TRF1-BFP-PYL1 (TERF1 Human)
   

   Expression

   Mammalian

   Promoter

   CMV

   Available Since

   Sept. 10, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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3. pSLQ14806

   Plasmid

   #239273

   Purpose

   Expresses TRF1-PYL1 for recruiting RNA to the nuclear stress body via CRISPR-TO

   Depositor

   Stanley Qi

   Article

   Han et al Nature. 2025 Jul;643(8070):241-251. doi:

   Insert

   HSF1-BFP-PYL1 (HSF1 Human)
   

   Use

   Lentiviral

   Expression

   Mammalian

   Promoter

   PGK

   Available Since

   Sept. 10, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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4. pSLQ10625

   Plasmid

   #239268

   Purpose

   Expresses NES-dCas13b-ABI for CRISPR-TO perturbation in primary mouse cortical neurons

   Depositor

   Stanley Qi

   Article

   Han et al Nature. 2025 Jul;643(8070):241-251. doi:

   Insert

   NES-dPspCas13b-EGFP-ABI
   

   Tags

   Flag tag and V5 tag

   Expression

   Mammalian

   Mutation

   H133A and H1058A in PspCas13b

   Promoter

   CAG

   Available Since

   Sept. 10, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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5. pSLQ10539

   Plasmid

   #239270

   Purpose

   Expresses PYL1-DDX6 for recruiting RNA to the p-body via CRISPR-TO

   Depositor

   Stanley Qi

   Article

   Han et al Nature. 2025 Jul;643(8070):241-251. doi:

   Insert

   PYL1-BFP-DDX6 (DDX6 Human)
   

   Use

   Lentiviral

   Expression

   Mammalian

   Promoter

   SFFV

   Available Since

   Sept. 10, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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6. pSLQ10531

   Plasmid

   #239267

   Purpose

   Expresses NLS-dCas13b-ABI for CRISPR-TO perturbation in the nucleus of cell lines

   Depositor

   Stanley Qi

   Article

   Han et al Nature. 2025 Jul;643(8070):241-251. doi:

   Insert

   NLS-dPspCas13b-EGFP-ABI
   

   Use

   CRISPR and Lentiviral

   Tags

   Flag tag and V5 tag

   Expression

   Mammalian

   Mutation

   H133A and H1058A in PspCas13b

   Promoter

   EF1a

   Available Since

   Sept. 10, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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7. pFUW-TetO-Mef2c

   Plasmid

   #207221

   Purpose

   doxycycline-inducible expression of Mouse Mef2c in mammalian cells

   Depositor

   Filipe Pereira

   Article

   Henriques-Oliveira et al Immunity. 58, 1-20. October 2025.

   Insert

   pFUW-TetO-Mef2c
   

   Use

   Lentiviral

   Expression

   Mammalian

   Promoter

   CMV

   Available Since

   Aug. 29, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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8. pFUW-TetO-IKZF2

   Plasmid

   #207216

   Purpose

   doxycycline-inducible expression of Human IKZF2 in mammalian cells

   Depositor

   Filipe Pereira

   Article

   Henriques-Oliveira et al Immunity. 58, 1-20. October 2025.

   Insert

   pFUW-TetO-IKZF2
   

   Use

   Lentiviral

   Expression

   Mammalian

   Promoter

   CMV

   Available Since

   Aug. 29, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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9. pCMV-HA-mCherry

   Plasmid

   #191136

   Purpose

   expresses mCherry in mammalian cells

   Depositor

   Ken-ichirou Morohashi

   Article

   Inoue et al Commun Biol. 2022 Sep 15;5(1):974. doi:

   Insert

   mCherry
   

   Expression

   Mammalian

   Available Since

   Aug. 11, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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10. pET21a asyn(Δ41-54/Δ103-130)

    Plasmid

    #242236

    Purpose

    Expresses alpha synuclein (missing exon 3 and 5, residues 41-54 and 103-130) in bacteria

    Depositor

    Jennifer Lee

    Article

    SanGiovanni et al Protein Sci. 2025 Jul;34(7):e70195. doi:

    Insert

    asyn(Δ41-54/Δ103-130)
    

    Tags

    none

    Expression

    Bacterial

    Mutation

    deleted amino acids 41-54 and 103-130

    Available Since

    Aug. 5, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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11. pET21a asyn(Δ103-130)

    Plasmid

    #242235

    Purpose

    Expresses alpha synuclein (missing exon 5, residues 103-130) in bacteria

    Depositor

    Jennifer Lee

    Article

    SanGiovanni et al Protein Sci. 2025 Jul;34(7):e70195. doi:

    Insert

    asyn(Δ103-130)
    

    Tags

    none

    Expression

    Bacterial

    Mutation

    deletion of residues 103-130

    Available Since

    Aug. 5, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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12. pET21a asyn(Δ41-54)

    Plasmid

    #242234

    Purpose

    Expresses alpha synuclein (missing exon 3, residues 41-54) in bacteria

    Depositor

    Jennifer Lee

    Article

    SanGiovanni et al Protein Sci. 2025 Jul;34(7):e70195. doi:

    Insert

    asyn(Δ41-54)
    

    Tags

    none

    Expression

    Bacterial

    Mutation

    deleted amino acids 41-54

    Available Since

    Aug. 5, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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13. AiP13787 - pAAV-AiE0140h_3xC2-minBG-iCre(R297T)-BGHpA (Alias: CN3787)

    Plasmid

    #230468

    Purpose

    AiE0140h_3xC2 is an enhancer sequence, designed to drive AAV-mediated transgene expression in specific populations of brain cells

    Depositor

    Allen Institute for Brain Science, Jonathan Ting

    Article

    Ben-Simon et al Cell. 2025 May 16:S0092-8674(25)00513-6.

    Insert

    iCre(R297T)
    

    Use

    AAV

    Promoter

    minBG

    Available Since

    May 30, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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14. pRK5_mEGFP-NUP98-DDX10-KS

    Plasmid

    #237644

    Purpose

    For overexpression of mEGFP-NUP98-DDX10-KS

    Depositor

    Denes Hnisz

    Article

    Zhang et al Nature. 2025 Jun 4. doi: 10.1038/s41586-

    Insert

    NUP98-DDX10-KS (NUP98, DDX10 Human)
    

    Tags

    mEGFP

    Expression

    Mammalian

    Available Since

    May 6, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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15. pCAGGS-MTS-TFAM-V5

    Plasmid

    #200813

    Purpose

    expresses MTS-TFAM in mammalian cells

    Depositor

    Hung-Chun Chang

    Insert

    Transcription Factor A, Mitochondrial (TFAM Human)
    

    Tags

    V5

    Expression

    Mammalian

    Promoter

    CAG

    Available Since

    April 2, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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16. HaloTag-LacI-KRAB

    Plasmid

    #232638

    Purpose

    lac repressor (LacI) which binds lacO sites; labeled with HaloTag and coupled with Krüppel-associated box (KRAB) repressor

    Depositor

    Karsten Rippe

    Insert

    HaloTag-LacI-KRAB
    

    Tags

    NLS

    Expression

    Mammalian

    Mutation

    none

    Promoter

    CMV

    Available Since

    Feb. 27, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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17. AiP15080 - pAAV-AiE0724m_3xC2-minBG-SYFP2-WPRE3-BGHpA (Alias: CN5080)

    Plasmid

    #229930

    Purpose

    AiE0724m_3xC2 is an enhancer sequence, designed to drive AAV-mediated transgene expression in specific brain cell types

    Depositor

    Allen Institute for Brain Science, Jonathan Ting

    Article

    Ben-Simon et al Cell. 2025 May 16:S0092-8674(25)00513-6.

    Insert

    SYFP2
    

    Use

    AAV

    Available Since

    Feb. 6, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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18. pPB-cT3G-cERP2-RARG

    Plasmid

    #222570

    Purpose

    PiggyBac transposon plasmid for doxycycline inducible expression of RARG

    Depositor

    George Church

    Article

    Pierson Smela et al bioRxiv 2024.05.31.596483

    Insert

    RARG (RARG Human)
    

    Expression

    Mammalian

    Available Since

    Aug. 15, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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19. pmiRFP670-C1-Nir1-LNS2

    Plasmid

    #220085

    Purpose

    high affinity PA biosensor with far-red fluorophore

    Depositor

    Gerry Hammond

    Article

    Weckerly et al J Cell Biol. 2025 Nov 3;224(11):e2024051

    Insert

    PITPNM3 (PITPNM3 Human)
    

    Tags

    iRFP670-GGSGGM

    Expression

    Mammalian

    Mutation

    amino acids 613-897

    Promoter

    CMV

    Available Since

    June 13, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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20. SGLT2(GFP)-MAP17(nb)

    Plasmid

    #216211

    Purpose

    for expression of human GFP-tagged SGLT2-MAP17 nanobody complex in BacMam system

    Depositor

    Lei Chen

    Article

    Cui et al Nat Commun. 2023 May 22;14(1):2920. doi:

    Insert

    SGLT2 GFP fusion and MAP17 nanobody fusion (PDZK1IP1, SLC5A2 Human)
    

    Tags

    GFP

    Expression

    Mammalian

    Available Since

    May 6, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

21. pαH-S-GSAS/XBB.1.5

    Plasmid

    #212991

    Purpose

    "Mammalian cell expression of SARS-CoV-2 Spike protein of Omicron.XBB.1.5 variant

    Depositor

    Priyamvada Acharya

    Article

    Zhang et al bioRxiv [Preprint]. 2024 Mar 12:2024.02.

    Insert

    pαH-S-GSAS/XBB.1.5 (S )
    

    Tags

    HRV 3C cleavage site (before tags) C terminal on …

    Expression

    Mammalian

    Mutation

    (T19I,Del24/26,A27S,V83A,G142D,Del144,H146Q,Q183E…

    Promoter

    CMV

    Available Since

    March 12, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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22. pDB2-hPER1-Luciferase-CD4-bla

    Plasmid

    #189981

    Purpose

    Donor Vector to integrate firefly Luciferase C-terminal into the human PER1 Locus to express it as a fusion protein

    Depositor

    Achim Kramer

    Article

    Gabriel et al Proc Natl Acad Sci U S A. 2024 Aug 20;12

    Insert

    Luciferase
    

    Use

    CRISPR

    Tags

    3xFlag

    Available Since

    Feb. 9, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

23. p3E_afp_UTR

    Plasmid

    #199341

    Purpose

    pAMS448; Gateway 3' entry clone encoding ocean pout antifreeze (afp) protein 3'UTR

    Depositor

    William Talbot

    Article

    Lysko et al Cell Rep. 2022 Nov 15;41(7):111669. doi:

    Insert

    afp 3' UTR
    

    Use

    Gateway donor vector

    Available Since

    April 26, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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24. Lenti-guide-puro mCsnk2b - 1

    Plasmid

    #198505

    Purpose

    lentiviral stable expression of mCsnk2b gRNA 1

    Depositor

    Suzanne Pfeffer

    Article

    Dhekne et al Elife. 2023 Oct 24;12:e87098. doi: 10.75

    Insert

    mCsnk2b (Csnk2b Mouse)
    

    Use

    Lentiviral

    Expression

    Mammalian

    Promoter

    U6

    Available Since

    April 21, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

25. Lenti-guide-puro mAtp5c-2

    Plasmid

    #198480

    Purpose

    lentiviral stable expression of mAtp5c gRNA 2

    Depositor

    Suzanne Pfeffer

    Article

    Dhekne et al Elife. 2023 Oct 24;12:e87098. doi: 10.75

    Insert

    mAtp5c (Atp5c1 Mouse)
    

    Use

    Lentiviral

    Expression

    Mammalian

    Promoter

    U6

    Available Since

    April 21, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

26. Lenti-guide-puro mCert1-1

    Plasmid

    #198487

    Purpose

    lentiviral stable expression of mCert1 gRNA 1

    Depositor

    Suzanne Pfeffer

    Article

    Dhekne et al Elife. 2023 Oct 24;12:e87098. doi: 10.75

    Insert

    mCert1 (Col4a3bp Mouse)
    

    Use

    Lentiviral

    Expression

    Mammalian

    Promoter

    U6

    Available Since

    April 21, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

27. Lenti-guide-puro mSptlc2 - 2

    Plasmid

    #198494

    Purpose

    lentiviral stable expression of mSptlc2 gRNA 2

    Depositor

    Suzanne Pfeffer

    Article

    Dhekne et al Elife. 2023 Oct 24;12:e87098. doi: 10.75

    Insert

    mSptlc2 (Sptlc2 Mouse)
    

    Use

    Lentiviral

    Expression

    Mammalian

    Promoter

    U6

    Available Since

    April 21, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

28. Lenti-guide-puro mPHB2-1

    Plasmid

    #198483

    Purpose

    lentiviral stable expression of mPHB2 gRNA 1

    Depositor

    Suzanne Pfeffer

    Article

    Dhekne et al Elife. 2023 Oct 24;12:e87098. doi: 10.75

    Insert

    mPhb2 (Phb2 Mouse)
    

    Use

    Lentiviral

    Expression

    Mammalian

    Promoter

    U6

    Available Since

    April 21, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

29. Lenti-guide-puro mHgs-2

    Plasmid

    #198482

    Purpose

    lentiviral stable expression of mHgs gRNA 2

    Depositor

    Suzanne Pfeffer

    Article

    Dhekne et al Elife. 2023 Oct 24;12:e87098. doi: 10.75

    Insert

    mHgs (Hgs Mouse)
    

    Use

    Lentiviral

    Expression

    Mammalian

    Promoter

    U6

    Available Since

    April 21, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

30. Lenti-guide-puro mCct8 - 1

    Plasmid

    #198503

    Purpose

    lentiviral stable expression of mCct8 gRNA 1

    Depositor

    Suzanne Pfeffer

    Article

    Dhekne et al Elife. 2023 Oct 24;12:e87098. doi: 10.75

    Insert

    mCct8 (Cct8 Mouse)
    

    Use

    Lentiviral

    Expression

    Mammalian

    Promoter

    U6

    Available Since

    April 21, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

31. pcDNA3.1-MS2-HA-HsRoquin2_AE

    Plasmid

    #148614

    Purpose

    Mammalian Expression of HsRoquin2

    Depositor

    Elisa Izaurralde

    Article

    Sgromo et al Nat Commun. 2017 Feb 6;8:14307. doi: 10.

    Insert

    HsRoquin2 (RC3H2 Human)
    

    Expression

    Mammalian

    Available Since

    March 16, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

32. pLV sgRNA-Hic1 GFP

    Plasmid

    #106953

    Purpose

    Lentivirus encoding sgRNA targeting murine Hic1. Includes GFP marker.

    Depositor

    Albert Edge

    Article

    Lenz et al Front Cell Dev Biol. 2019 Feb 19;7:14. d

    Insert

    anti-Hic1 sgRNA
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Available Since

    Dec. 12, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

33. pET30-T7-lacO-His-sfGFP

    Plasmid

    #180754

    Purpose

    pET30 vector with sfGFP-S-tag inserted between the Bgl II and T7 terminator

    Depositor

    Michael Black

    Article

    Jew et al Front Bioeng Biotechnol. 2022 Jun 23;10:

    Insert

    superfolder green fluorescent protein
    

    Tags

    strep tag

    Expression

    Bacterial

    Mutation

    G140C- Please see depositor comments

    Available Since

    July 19, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

34. pDONR221-SLC29A2_STOP

    Plasmid

    #161305

    Purpose

    Gateway entry clone with codon-optimized ORF sequence for subcloning into custom expression vectors. Contains a STOP codon at the end of the codon-optimized ORF sequence.

    Depositor

    RESOLUTE Consortium, Giulio Superti-Furga

    Article

    Superti-Furga et al Nat Rev Drug Discov. 2020 Jul;19(7):429-

    Insert

    SLC29A2 (SLC29A2 Human)
    

    Expression

    Mammalian

    Available Since

    Sept. 15, 2021

    Availability

    Industry, Academic Institutions, and Nonprofits

    

    Enlarge

35. AAVS1 intron 1 gRNA as2

    Plasmid

    #132394

    Purpose

    Targets AAVS1 intron 1, gRNA: AGAACCAGAGCCACATTAAC, MLM3636 backbone

    Depositor

    Gerold Schmitt-Ulms

    Article

    Wang et al Bio Protoc. 2020 May 5;10(9):e3615. doi:

    Insert

    gRNA targeting AAVS1 intron 1 (PPP1R12C Human)
    

    Use

    CRISPR

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    May 6, 2020

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

36. pIGc-Xph20

    Plasmid

    #133024

    Purpose

    Expresses Xph20 in bacteria

    Depositor

    Matthieu Sainlos

    Article

    Rimbault et al Nat Commun. 2019 Oct 4;10(1):4521. doi:

    Insert

    Xph20
    

    Tags

    His10

    Expression

    Bacterial

    Mutation

    S63K

    Promoter

    T7

    Available Since

    Nov. 25, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

37. KA2896_pPB-TREtight-Tkmin-cHA-IRESH2BmKO2

    Plasmid

    #124175

    Purpose

    piggyBac-based Dox-inducible expression (very weak)

    Depositor

    Hans Schöler

    Article

    Adachi et al Cell Stem Cell. 2018 Aug 2;23(2):266-275

    Type

    Empty backbone

    Expression

    Mammalian

    Available Since

    March 29, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

38. KA2895_pPB-TREtight-TATAmin-cHA-IRESH2BmKO2

    Plasmid

    #124174

    Purpose

    piggyBac-based Dox-inducible expression (weak)

    Depositor

    Hans Schöler

    Article

    Adachi et al Cell Stem Cell. 2018 Aug 2;23(2):266-275

    Type

    Empty backbone

    Expression

    Mammalian

    Available Since

    March 29, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

39. pTXB1-Tn5

    Plasmid

    #60240

    Purpose

    IPTG-inducible expression of Transposon Tn5 fused to Mxe Intein and Chitin-binding domain.

    Depositor

    Rickard Sandberg

    Article

    Picelli et al Genome Res. 2014 Jul 30. pii: gr.177881.

    Insert

    tnpA from pBam1
    

    Tags

    Mxe intein - Chitin-binding domain

    Expression

    Bacterial

    Mutation

    E54K, L372P

    Promoter

    T7 promoter

    Available Since

    Nov. 18, 2014

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

40. pAAV-hSyn-hChR2(H134R)-EYFP (AAV9)

    Viral Prep

    #26973-AAV9

    Purpose

    Ready-to-use AAV9 particles produced from pAAV-hSyn-hChR2(H134R)-EYFP (#26973). In addition to the viral particles, you will also receive purified pAAV-hSyn-hChR2(H134R)-EYFP plasmid DNA. hSyn-driven, humanized channelrhodopsin H134R mutant fused to EYFP for optogenetic activation. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Karl Deisseroth

    Promoter

    Syn

    Tags

    EYFP

    Available Since

    April 3, 2018

    Availability

    Academic Institutions and Nonprofits only