We narrowed to 80 results for: SHP2

1. Shp2 biosensor

   Plasmid

   #134346

   Purpose

   FRET biosensor. To visualize Shp2 activity by FRET

   Depositor

   Yingxiao Wang

   Article

   Sun et al Nat Commun. 2017 Sep 7;8(1):477. doi: 10

   Insert

   Shp2 Biosensor
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   Nov. 22, 2019

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

2. pCMV-SHP2 WT

   Plasmid

   #8381

   Depositor

   Ben Neel

   Insert

   SHP2 (PTPN11 Human)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   Aug. 15, 2005

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

3. pCMV-SHP2 CS

   Plasmid

   #8382

   Depositor

   Ben Neel

   Insert

   SHP2 (PTPN11 Human)
   

   Use

   Tags

   HA

   Expression

   Mammalian

   Mutation

   C459S, mutation of essential catalytic cysteine

   Promoter

   Available since

   Sept. 26, 2005

   Availability

   Academic Institutions and Nonprofits only

4. pJ3 SHP2 WT

   Plasmid

   #8317

   Depositor

   Ben Neel

   Article

   Bennett et al Mol Cell Biol 1996 Mar;16(3):1189-202.

   Insert

   SHP2 (PTPN11 Human)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   June 17, 2005

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

5. pJ3 SHP2 CS

   Plasmid

   #8319

   Depositor

   Ben Neel

   Article

   Bennett et al Mol Cell Biol 1996 Mar;16(3):1189-202.

   Insert

   SHP2 (PTPN11 Human)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   C459S, mutation of essential catalytic cysteine

   Promoter

   Available since

   June 17, 2005

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

6. pSP64R1 SHP2 WT

   Plasmid

   #8325

   Depositor

   Ben Neel

   Article

   O'Reilly et al Mol Cell Biol 2000 Jan;20(1):299-311.

   Insert

   SHP2 (PTPN11 Human)
   

   Use

   Xenopus expression

   Tags

   Expression

   Mutation

   Promoter

   Available since

   June 17, 2005

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

7. pIRES2-EGFP-SHP2WT

   Plasmid

   #12283

   Depositor

   Anton Bennett

   Article

   Kolli et al J Biol Chem. 2004 Jul 9. 279(28):29374-8

   Insert

   SHP-2WT (PTPN11 Human)
   

   Use

   Tags

   Myc (not canonical: KLISEEDL)

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   Aug. 11, 2006

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

8. pBABE-puro SHP2 WT

   Plasmid

   #8329

   Depositor

   Ben Neel

   Article

   Zhang et al Mol Cell Biol 2002 Jun;22(12):4062-72.

   Insert

   SHP2 (PTPN11 Human)
   

   Use

   Retroviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   June 17, 2005

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

9. pGEX-4T1 SHP2 WT

   Plasmid

   #8322

   Depositor

   Ben Neel

   Article

   O'Reilly et al Mol Cell Biol 2000 Jan;20(1):299-311.

   Insert

   SHP2 (PTPN11 Human)
   

   Use

   Tags

   GST

   Expression

   Bacterial

   Mutation

   Promoter

   Available since

   March 14, 2006

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. pIRES2-EGFP-SHP2CS

    Plasmid

    #12284

    Depositor

    Anton Bennett

    Article

    Kolli et al J Biol Chem. 2004 Jul 9. 279(28):29374-8

    Insert

    SHP-2CS (PTPN11 Human)
    

    Use

    Tags

    Myc

    Expression

    Mammalian

    Mutation

    Cysteine 459 mutated to Serine

    Promoter

    Available since

    Aug. 11, 2006

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

11. pIRES2-EGFP-SHP2DA

    Plasmid

    #12286

    Depositor

    Anton Bennett

    Article

    Kolli et al J Biol Chem. 2004 Jul 9. 279(28):29374-8

    Insert

    SHP-2DA (PTPN11 Human)
    

    Use

    Tags

    Myc

    Expression

    Mammalian

    Mutation

    Aspartic Acid 425 mutated to Alanine

    Promoter

    Available since

    Aug. 11, 2006

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

12. pJ3 SHP2 D61A

    Plasmid

    #8320

    Depositor

    Ben Neel

    Article

    Bennett et al Mol Cell Biol 1996 Mar;16(3):1189-202.

    Insert

    SHP2 (PTPN11 Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    D61A (activated mutant)

    Promoter

    Available since

    June 17, 2005

    Availability

    Academic Institutions and Nonprofits only

13. pJ3 SHP2 E76A

    Plasmid

    #8321

    Depositor

    Ben Neel

    Article

    Bennett et al Mol Cell Biol 1996 Mar;16(3):1189-202.

    Insert

    SHP2 (PTPN11 Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    E76A (activated mutant)

    Promoter

    Available since

    June 17, 2005

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. pFastBac(His10-Shp2)

    Plasmid

    #177899

    Purpose

    Baculo expression of His10 tag fused to human Shp2

    Depositor

    Ron Vale

    Article

    Hui et al Science. 2017 Mar 31;355(6332):1428-1433

    Insert

    Shp2 (PTPN11 Human)
    

    Use

    Tags

    10xHis-TEV-SNAP tag

    Expression

    Insect

    Mutation

    Promoter

    Polyhedrin

    Available since

    April 11, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. MDH1-shSHP2-3-H2Kb2

    Plasmid

    #17854

    Depositor

    Chang-Zheng Chen

    Article

    Li et al Cell. 2007 Apr 6. 129(1):147-61.

    Insert

    shSHP2 (PTPN11 Human)
    

    Use

    RNAi and Retroviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    May 16, 2008

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. pSP64R1 SHP2 D61A

    Plasmid

    #8326

    Depositor

    Ben Neel

    Article

    O'Reilly et al Mol Cell Biol 2000 Jan;20(1):299-311.

    Insert

    SHP2 (PTPN11 Human)
    

    Use

    Xenopus expression

    Tags

    Expression

    Mutation

    D61A (activated mutant)

    Promoter

    Available since

    June 17, 2005

    Availability

    Academic Institutions and Nonprofits only

17. pGEX-4T-1-Shp2 SH2s

    Plasmid

    #67575

    Purpose

    Expresses GST-tagged Shp2 SH2 domains in bacteria

    Depositor

    Graeme Carnegie

    Article

    Burmeister et al J Biol Chem. 2015 May 8;290(19):12058-67

    Insert

    Src homology 2 domain-containing phosphatase 2 SH2s
    

    Use

    Tags

    GST

    Expression

    Bacterial

    Mutation

    Deleted amino acids 219-597

    Promoter

    Available since

    Sept. 14, 2015

    Availability

    Academic Institutions and Nonprofits only

18. pSP64R1 SHP2 E76A

    Plasmid

    #8327

    Depositor

    Ben Neel

    Article

    O'Reilly et al Mol Cell Biol 2000 Jan;20(1):299-311.

    Insert

    SHP2 (PTPN11 Human)
    

    Use

    Xenopus expression

    Tags

    Expression

    Mutation

    E76A (activated mutant)

    Promoter

    Available since

    June 17, 2005

    Availability

    Academic Institutions and Nonprofits only

19. pLV-shP2rx4-1026

    Plasmid

    #99034

    Purpose

    Expresses a shRNA targeting the rat P2rx4 gene

    Depositor

    Amy Lasek

    Article

    Franklin et al Alcohol Clin Exp Res. 2015 Oct;39(10):20

    Insert

    P2rx4 shRNA (P2rx4 Rat)
    

    Use

    Lentiviral and RNAi

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    mouse U6

    Available since

    March 5, 2018

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. pBABE-puro SHP2 E76A

    Plasmid

    #8331

    Depositor

    Ben Neel

    Article

    Zhang et al Mol Cell Biol 2002 Jun;22(12):4062-72.

    Insert

    SHP2 (PTPN11 Human)
    

    Use

    Retroviral

    Tags

    Expression

    Mammalian

    Mutation

    E76A (activated mutant)

    Promoter

    Available since

    June 17, 2005

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

21. SHP2(WT)@pLKO-Trex-SBP

    Plasmid

    #85457

    Purpose

    Gene expression

    Depositor

    Darrin Stuart

    Article

    Chen et al Nature. 2016 Jul 7;535(7610):148-52.

    Insert

    SHP2 (PTPN11 Human)
    

    Use

    Lentiviral

    Tags

    SBP Tag

    Expression

    Mammalian

    Mutation

    Promoter

    RSV

    Available since

    Feb. 6, 2017

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

22. pFastBac (GST-SNAP-Shp2)

    Plasmid

    #177897

    Purpose

    Baculo expression of GST tag fused to SNAP tag and human Shp2

    Depositor

    Ron Vale

    Article

    Hui et al Science. 2017 Mar 31;355(6332):1428-1433

    Insert

    Shp2 (PTPN11 Human)
    

    Use

    Tags

    TEV-GST-PreScission cut site-SNAP tag

    Expression

    Insect

    Mutation

    Promoter

    Polyhedrin

    Available since

    Dec. 18, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

23. SHP2(C459S)@pLKO-Trex-HA

    Plasmid

    #85459

    Purpose

    Expresses SHP2 mutant in mammalian cells

    Depositor

    Darrin Stuart

    Article

    Chen et al Nature. 2016 Jul 7;535(7610):148-52.

    Insert

    SHP2 (PTPN11 Human)
    

    Use

    Lentiviral

    Tags

    HA

    Expression

    Mammalian

    Mutation

    C459S

    Promoter

    RSV

    Available since

    Feb. 6, 2017

    Availability

    Academic Institutions and Nonprofits only

24. RapR-Shp2-mVenus-flag

    Plasmid

    #188655

    Purpose

    Rapamycin regulated Shp2 phosphatase with mVenus and flag tag

    Depositor

    Andrei Karginov

    Article

    Fauser et al J Cell Biol. 2022 Aug 1;221(8). pii: 213

    Insert

    Shp2
    

    Use

    Tags

    Flag and mVenus

    Expression

    Mammalian

    Mutation

    iFKBP insertion at V406 with deletion of residues…

    Promoter

    CMV

    Available since

    Aug. 19, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

25. pBABE-puro SHP2 D61A

    Plasmid

    #8330

    Depositor

    Ben Neel

    Article

    Zhang et al Mol Cell Biol 2002 Jun;22(12):4062-72.

    Insert

    SHP2 (PTPN11 Human)
    

    Use

    Retroviral

    Tags

    Expression

    Mammalian

    Mutation

    D61A (activated mutant)

    Promoter

    Available since

    June 23, 2005

    Availability

    Academic Institutions and Nonprofits only

26. pGEX-4T2 SHP2 E76A

    Plasmid

    #8324

    Depositor

    Ben Neel

    Article

    O'Reilly et al Mol Cell Biol 2000 Jan;20(1):299-311.

    Insert

    SHP2 (PTPN11 Human)
    

    Use

    Tags

    GST

    Expression

    Bacterial

    Mutation

    E76A (activated mutant)

    Promoter

    Available since

    June 17, 2005

    Availability

    Academic Institutions and Nonprofits only

27. pGEX-4T2 SHP2 D61A

    Plasmid

    #8323

    Depositor

    Ben Neel

    Article

    O'Reilly et al Mol Cell Biol 2000 Jan;20(1):299-311.

    Insert

    SHP2 (PTPN11 Human)
    

    Use

    Tags

    GST

    Expression

    Bacterial

    Mutation

    D61A (activated mutant)

    Promoter

    Available since

    June 17, 2005

    Availability

    Academic Institutions and Nonprofits only

28. pGEX6P2(GST-SNAP-Shp2tSH2)

    Plasmid

    #177907

    Purpose

    Baculo expression of GST tag fused to SNAPtag and human Shp2 tandem SH2 domains

    Depositor

    Ron Vale

    Article

    Hui et al Science. 2017 Mar 31;355(6332):1428-1433

    Insert

    Shp2 tandem SH2 domains (aa 6-218 only) (PTPN11 Human)
    

    Use

    Tags

    GST-PreScission cut site-SNAP tag

    Expression

    Bacterial

    Mutation

    Promoter

    tac

    Available since

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

29. pMIG II SIN-SV40-mCherry-SHP2

    Plasmid

    #180800

    Purpose

    Expression of mouse SHP2 fused to N-terminal mCherry

    Depositor

    Enfu Hui

    Article

    Xu et al J Cell Biol. 2020 Jun 1;219(6). pii: 151

    Insert

    SHP2 (Ptpn11 Mouse)
    

    Use

    Retroviral

    Tags

    Expression

    Mutation

    Promoter

    SV40

    Available since

    March 15, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

30. pGEX-4T-1-Shp2 T7DA/S189D SH2s

    Plasmid

    #67577

    Purpose

    Expresses GST-tagged Shp2 T73D/S189D SH2 domains in bacteria

    Depositor

    Graeme Carnegie

    Article

    Burmeister et al J Biol Chem. 2015 May 8;290(19):12058-67

    Insert

    Src homology 2 domain-containing phosphatase 2
    

    Use

    Tags

    GST

    Expression

    Bacterial

    Mutation

    Deleted amino acid residues 219-597, changed T73 …

    Promoter

    Available since

    Sept. 14, 2015

    Availability

    Academic Institutions and Nonprofits only

31. SHP2(T253M/Q257L)@pLKO-Trex-SBP

    Plasmid

    #85458

    Purpose

    SHP2 mutant gene expression

    Depositor

    Darrin Stuart

    Article

    Chen et al Nature. 2016 Jul 7;535(7610):148-52.

    Insert

    SHP2 (PTPN11 Human)
    

    Use

    Lentiviral

    Tags

    SBP Tag

    Expression

    Mammalian

    Mutation

    T253M/Q257L

    Promoter

    RSV

    Available since

    Feb. 6, 2017

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

32. pHR-SV40-mCherry-SHP1 (SHP2-cSH2)

    Plasmid

    #180822

    Purpose

    Expression of N-terminal mCherry tagged human SHP1 with its cSH2 replaced by SHP2-cSH2

    Depositor

    Enfu Hui

    Article

    Xu et al Elife. 2021 Nov 4;10. pii: 74276. doi: 1

    Insert

    SHP1 (SHP2-cSH2) (PTPN6, PTPN11 Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    SV40

    Available since

    March 14, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

33. pHR-SV40-mCherry-SHP1 (SHP2-nSH2, cSH2)

    Plasmid

    #180823

    Purpose

    Expression of N-terminal mCherry tagged human SHP1 with its nSH2 and cSH2 replaced by nSH2 and cSH2 of SHP2

    Depositor

    Enfu Hui

    Article

    Xu et al Elife. 2021 Nov 4;10. pii: 74276. doi: 1

    Insert

    SHP1 (SHP2-nSH2, cSH2) (PTPN6, PTPN11 Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    SV40

    Available since

    March 14, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

34. pGEX SHP-2(N)-SH2

    Plasmid

    #46498

    Depositor

    Bruce Mayer

    Article

    Machida et al Mol Cell. 2007 Jun 22;26(6):899-915.

    Insert

    SHP-2(N) (PTPN11 Human)
    

    Use

    Tags

    GST and PreScission

    Expression

    Bacterial

    Mutation

    contains amino acids 1-104

    Promoter

    Tac

    Available since

    July 10, 2013

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

35. pGEX SHP-2(NC)-SH2

    Plasmid

    #46499

    Depositor

    Bruce Mayer

    Article

    Machida et al Mol Cell. 2007 Jun 22;26(6):899-915.

    Insert

    SHP-2(NC) (PTPN11 Human)
    

    Use

    Tags

    GST and PreScission

    Expression

    Bacterial

    Mutation

    contains amino acids 1-222

    Promoter

    Tac

    Available since

    July 10, 2013

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

36. pGEX SHP-2(C)-SH2

    Plasmid

    #46497

    Depositor

    Bruce Mayer

    Article

    Machida et al Mol Cell. 2007 Jun 22;26(6):899-915.

    Insert

    SHP-2(C) (PTPN11 Human)
    

    Use

    Tags

    GST and PreScission

    Expression

    Bacterial

    Mutation

    contains amino acids 101-222

    Promoter

    Tac

    Available since

    July 10, 2013

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

37. pENTR2b-PTPN11

    Plasmid

    #215476

    Purpose

    Gateway entry vector with Shp2

    Depositor

    Johanna Ivaska

    Article

    Conway et al Nat Cell Biol. 2025 May 26. doi: 10.1038

    Insert

    PTPN11 (PTPN11 Human)
    

    Use

    Gateway entry vector

    Tags

    Expression

    Mutation

    Promoter

    none

    Available since

    May 29, 2025

    Availability

    Industry, Academic Institutions, and Nonprofits

    

    Enlarge

38. pENTR2b-PTPN11-Clover

    Plasmid

    #215519

    Purpose

    Gateway entry vector with clover-tagged Shp2

    Depositor

    Johanna Ivaska

    Article

    Conway et al Nat Cell Biol. 2025 May 26. doi: 10.1038

    Insert

    PTPN11 (PTPN11 Human)
    

    Use

    Gateway entry vector

    Tags

    Clover

    Expression

    Mutation

    Promoter

    none

    Available since

    May 29, 2025

    Availability

    Industry, Academic Institutions, and Nonprofits

    

    Enlarge

39. pEF.DEST51-PTPN11

    Plasmid

    #215523

    Purpose

    Expression vector with Shp2

    Depositor

    Johanna Ivaska

    Article

    Conway et al Nat Cell Biol. 2025 May 26. doi: 10.1038

    Insert

    PTPN11 (PTPN11 Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    EF1a

    Available since

    May 29, 2025

    Availability

    Industry, Academic Institutions, and Nonprofits

    

    Enlarge

40. pEF.DEST51-PTPN11-Clover

    Plasmid

    #215525

    Purpose

    Expression vector with clover-tagged Shp2

    Depositor

    Johanna Ivaska

    Article

    Conway et al Nat Cell Biol. 2025 May 26. doi: 10.1038

    Insert

    PTPN11 (PTPN11 Human)
    

    Use

    Tags

    Clover

    Expression

    Mammalian

    Mutation

    Promoter

    EF1a

    Available since

    May 29, 2025

    Availability

    Industry, Academic Institutions, and Nonprofits

    

    Enlarge