We narrowed to 31,327 results for: uros

1. Human b4 nicotinic receptor subunit EM construct

   Plasmid

   #163961

   Purpose

   pEZT-BM vector with beta4 gene after CMV promoter, published EM construct

   Depositor

   Ryan Hibbs

   Article

   Gharpure et al Neuron. 2019 Nov 6;104(3):501-511.e6. do

   Insert

   Human beta4 nicotinic acetylcholine receptor subunit EM construct
   

   Use

   Baculovirus (bacmam) production and mammalian exp…

   Tags

   StrepII tag and apocytochrome b(562)RIL (BRIL)

   Expression

   Mammalian

   Mutation

   Pro341-Ser395 replaced with apocytochrome b(562)R…

   Promoter

   CMV

   Available Since

   Feb. 5, 2021

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

2. pcDNA3-CMV-Grid2(I677C)

   Plasmid

   #164782

   Purpose

   cysteine mutated glutamate delta2 receptor (I677C) for the attachment of a photoswitchable tethered ligand

   Depositor

   Alexandre Mourot

   Article

   Lemoine et al Elife. 2020 Oct 28;9. pii: 59026. doi: 1

   Insert

   Grid2 I677C (Grid2 Mouse)
   

   Expression

   Mammalian

   Mutation

   I677C

   Promoter

   CMV

   Available Since

   April 13, 2021

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

3. lentiCRISPR v2-sgBAX-2

   Plasmid

   #210130

   Purpose

   knock out BAX in mammalian cells

   Depositor

   Boyi Gan

   Article

   Liu et al Nat Cell Biol. 2023 Mar;25(3):404-414. d

   Insert

   Apoptosis regulator BAX (BAX Human)
   

   Use

   CRISPR

   Available Since

   Nov. 8, 2023

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

4. hSyn-somAion-citrine

   Plasmid

   #192570

   Purpose

   AAV-vector for optogenetic long-term silencing of neurons

   Depositor

   Simon Wiegert

   Article

   Rodriguez-Rozada et al Commun Biol. 2022 Jul 9;5(1):687. doi: 1

   Insert

   somAion
   

   Use

   AAV

   Tags

   Citrine - soma-targeting motif from Kv2.1 channel

   Expression

   Mammalian

   Mutation

   T59S, E83N, E90Q, E101S, V117R, E123S, C128A,D156…

   Promoter

   human synapsin

   Available Since

   Dec. 14, 2022

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

5. pcDNA5 FRT TO Myc ArB WT RNAiR

   Plasmid

   #59806

   Purpose

   Allows the integration of Myc ArB in the genome and Tet-inducible expression.

   Depositor

   Stephen Taylor

   Article

   Girdler et al J Cell Sci. 2006 Sep 1;119(Pt 17):3664-7

   Insert

   Aurora B (AURKB Human)
   

   Tags

   Myc

   Expression

   Mammalian

   Mutation

   RNAi resistant

   Promoter

   hybrid human cytomegalovirus (CMV)/TetO2 promoter

   Available Since

   Feb. 18, 2015

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

6. pENTR-E2F1

   Plasmid

   #37141

   Depositor

   Robert Duronio

   Article

   Shibutani et al Dev Cell. 2008 Dec;15(6):890-900.

   Insert

   E2F1 (E2f1 Fly)
   

   Use

   Gateway

   Available Since

   June 21, 2012

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

7. pMRX-IP-hWIPI1A-3×FLAG

   Plasmid

   #215509

   Purpose

   Expresses FLAG tagged human WIPI1A.

   Depositor

   Noboru Mizushima

   Article

   Shimizu et al Hum Mol Genet. 2023 Aug 7;32(16):2623-26

   Insert

   WD-repeat protein interacting with phosphoinositides 1A (WIPI1 Human)
   

   Use

   Retroviral

   Tags

   3×FLAG

   Expression

   Mammalian

   Available Since

   May 20, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

8. pAAV.CMV.SV40.THBS1-deltaCTD-HA.SV40(polyA)

   Plasmid

   #156163

   Purpose

   Expresses truncated (AA 1-954) murine Thrombospondin-1 (THBS1) protein with HA-tag at C-terminus

   Depositor

   Kevin Park

   Article

   Bray et al Neuron. 2019 Aug 21;103(4):642-657.e7. d

   Insert

   Thrombospondin-1 (Thbs1 Mouse)
   

   Use

   AAV

   Tags

   HA-tag

   Expression

   Mammalian

   Mutation

   Truncated THBS1 (amino acid residues 1-954)

   Promoter

   CMV

   Available Since

   Aug. 25, 2020

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

9. pLX307 DEDD

   Plasmid

   #117744

   Purpose

   Open reading frame vector encoding DEDD

   Depositor

   William Hahn

   Article

   Hong et al Mol Cancer Res. 2019 Feb 18. pii: 1541-7

   Insert

   DEDD1 (DEDD Human)
   

   Use

   Lentiviral

   Tags

   V5

   Expression

   Mammalian

   Promoter

   EF1a

   Available Since

   Feb. 21, 2019

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. pDEST53-LRRK2-K1347A

    Plasmid

    #25052

    Depositor

    Mark Cookson

    Article

    Greggio et al Neurobiol Dis. 2006 Aug . 23(2):329-41.

    Insert

    LRRK2 (LRRK2 Human)
    

    Tags

    GFP

    Expression

    Mammalian

    Mutation

    Lysine 1347 mutated to Alanine

    Available Since

    June 29, 2010

    Availability

    Academic Institutions and Nonprofits only

11. pDisplay-EGFP-2A-HA-Nrxn3-alpha- 2(-)/3(+)/4(+)/6(-)-GPI

    Plasmid

    #184335

    Purpose

    Expression of GPI-anchored form of mouse Nrx3-alpha containing the alternative splice site 5 together with EGFP protein separated by 2A peptide. Contains insertions at alternatively splice sites 1,3,

    Depositor

    Peter Scheiffele

    Article

    Hauser et al Neuron. 2022 May 8. pii: S0896-6273(22)0

    Insert

    Nrxn3-alpha-GPI (Nrxn3 Mouse)
    

    Tags

    HA-tag

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    Aug. 26, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

12. pcDNA5-FRT-T0-Flag-HROB

    Plasmid

    #135298

    Purpose

    Expresses Flag-tagged HROB in mammalian cells

    Depositor

    Daniel Durocher

    Article

    Hustedt et al Genes Dev. 2019 Oct 1;33(19-20):1397-141

    Insert

    HROB (HROB Human)
    

    Tags

    Flag

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    March 2, 2020

    Availability

    Industry, Academic Institutions, and Nonprofits

    

    Enlarge

13. pT7-7 asyn S87E

    Plasmid

    #36059

    Depositor

    Hilal Lashuel

    Article

    Paleologou et al J Neurosci. 2010 Mar 3;30(9):3184-98.

    Insert

    alpha-synuclein S87E (SNCA Human)
    

    Expression

    Bacterial

    Mutation

    S87E

    Promoter

    T7

    Available Since

    July 13, 2012

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. pAAV-mA93-RFP

    Plasmid

    #22918

    Depositor

    Edward Callaway

    Article

    Nathanson et al Front Neural Circuits. 2009 Nov 9;3:19.

    Insert

    mouse riken gene A930038C07Rik promoter driving DsRedExpress (A930038C07Rik Mouse)
    

    Use

    AAV

    Expression

    Mammalian

    Available Since

    Aug. 26, 2010

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. pT7-7 asyn S87A

    Plasmid

    #36058

    Depositor

    Hilal Lashuel

    Article

    Paleologou et al J Neurosci. 2010 Mar 3;30(9):3184-98.

    Insert

    alpha-synuclein S87A (SNCA Human)
    

    Expression

    Bacterial

    Mutation

    S87A

    Promoter

    T7

    Available Since

    July 13, 2012

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. pDEST-FRT/T0-GFP-BRCA1 1364-1437

    Plasmid

    #71119

    Purpose

    Mammalian expression of GFP-BRCA1 1364-1437

    Depositor

    Daniel Durocher

    Article

    Orthwein et al Nature. 2015 Dec 9. doi: 10.1038/nature1

    Insert

    BRCA1 (BRCA1 Human)
    

    Tags

    GFP

    Expression

    Mammalian

    Mutation

    contains amino acids 1364-1437 of BRCA1

    Promoter

    CMV/TO

    Available Since

    Dec. 9, 2015

    Availability

    Industry, Academic Institutions, and Nonprofits

    

    Enlarge

17. pAAV-Ef1a-DIO-Egr3-EYFP-WPRE

    Plasmid

    #186417

    Purpose

    Overexpression of Egr3 transcript variant 1 CDS under EF-1α promoter

    Depositor

    Mary Kay Lobo

    Article

    Chandra et al J Neurosci. 2015 May 20;35(20):7927-37.

    Insert

    Early growth response 3 (Egr3 Mouse)
    

    Use

    AAV

    Tags

    EYFP

    Promoter

    EF-1-alpha

    Available Since

    July 27, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. Kv7.4 (1-645, Δ368-523)/HA tag/pcDNA3.1

    Plasmid

    #111459

    Purpose

    Electrophysiology in HEK cell

    Depositor

    Dan Minor

    Article

    Chang et al Neuron. 2018 Feb 21;97(4):836-852.e6. do

    Insert

    potassium voltage-gated channel subfamily KQT member 4 isoform a [Homo sapiens] (KCNQ4 Human)
    

    Tags

    Ha Tag

    Expression

    Mammalian

    Mutation

    Kv7.4 (1-645, Δ368-523), C643A

    Available Since

    Oct. 31, 2018

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. pMCh2007_pLenti_Syn_mChe-cdc42E7

    Plasmid

    #118620

    Purpose

    expression of mChe-tagged cdc42E7 under pSyn promoter for primary neurons

    Depositor

    Marina Chekulaeva

    Article

    Ciolli Mattioli et al Nucleic Acids Res. 2018 Dec 22. pii: 525

    Insert

    cdc42E7 (Cdc42 Mouse)
    

    Use

    Lentiviral

    Tags

    mCherry

    Expression

    Mammalian

    Mutation

    changed cagtctg to ggcataa (667 - 673 nt in 3…

    Promoter

    synapsin I (rat)

    Available Since

    Jan. 2, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. p2xFLAGhYAP2-WW1-mutant

    Plasmid

    #17795

    Depositor

    Marius Sudol

    Article

    Komuro et al J Biol Chem. 2003 Aug 29. 278(35):33334-

    Insert

    Yes-kinase associated protein (YAP1 Human)
    

    Tags

    2xFlag

    Expression

    Mammalian

    Mutation

    Tryptophan 199 to Alanine; Proline 202 to Alanine

    Available Since

    May 9, 2008

    Availability

    Academic Institutions and Nonprofits only

21. p2xFLAGhYAP2-WW2-mutant

    Plasmid

    #17796

    Depositor

    Marius Sudol

    Article

    Komuro et al J Biol Chem. 2003 Aug 29. 278(35):33334-

    Insert

    Yes-kinase associated protein (YAP1 Human)
    

    Tags

    2xFlag

    Expression

    Mammalian

    Mutation

    Tryptophan 258 to Alanine Proline 261 to Alanine

    Available Since

    May 9, 2008

    Availability

    Academic Institutions and Nonprofits only

22. pTBL681 CHYRON4 integration construct

    Plasmid

    #126449

    Purpose

    To integrate the CHYRON4 locus at AAVS1 in human cells.

    Depositor

    Chang Liu

    Article

    Loveless et al Nat Chem Biol. 2021 Jun;17(6):739-747. d

    Inserts

    pU6/3xLacO-CHYRON4 hgRNA
    pCMV-puro
    

    Expression

    Mammalian

    Mutation

    The SpCas9 sgRNA constant region is mutated to ma…

    Promoter

    CMV and human U6/3xLacO

    Available Since

    June 4, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

23. pLenti-CMV-cGAS R71/75E C396/7A-HA

    Plasmid

    #130920

    Purpose

    Expresses human cGAS with R71/75E and C396/397A point mutations; Puromycin selection marker

    Depositor

    Jonathan Kagan

    Article

    Barnett et al Cell. 2019 Mar 7;176(6):1432-1446.e11. d

    Insert

    human cGAS R71/75E C396/7A
    

    Tags

    HA

    Expression

    Mammalian

    Mutation

    aa 71 and 75 mutated to glutamate; aa 396 and 397…

    Promoter

    CMV

    Available Since

    Aug. 27, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

24. pcDNA5 TO FRT Myc ArB K106R

    Plasmid

    #59807

    Purpose

    Allows the integration of Myc ArB K106R in the genome and Tet-inducible expression

    Depositor

    Stephen Taylor

    Article

    Girdler et al J Cell Sci. 2006 Sep 1;119(Pt 17):3664-7

    Insert

    Aurora B (AURKB Human)
    

    Tags

    Myc

    Expression

    Mammalian

    Mutation

    K106R, kinase mutant

    Promoter

    hybrid human cytomegalovirus (CMV)/TetO2 promoter

    Available Since

    Feb. 18, 2015

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

25. pcDNA5-FRT-T0-eGFP-HROB

    Plasmid

    #135299

    Purpose

    Expresses eGFP-tagged HROB in mammalian cells

    Depositor

    Daniel Durocher

    Article

    Hustedt et al Genes Dev. 2019 Oct 1;33(19-20):1397-141

    Insert

    HROB (HROB Human)
    

    Tags

    eGFP

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    March 2, 2020

    Availability

    Industry, Academic Institutions, and Nonprofits

    

    Enlarge

26. pTBL649 CHYRON2 integration construct

    Plasmid

    #126446

    Purpose

    To integrate the CHYRON2 locus at AAVS1 in human cells.

    Depositor

    Chang Liu

    Article

    Loveless et al Nat Chem Biol. 2021 Jun;17(6):739-747. d

    Inserts

    pU6-CHYRON2 hgRNA
    pCMV-puro
    

    Expression

    Mammalian

    Mutation

    The SpCas9 sgRNA constant region is mutated to ma…

    Promoter

    CMV and human U6

    Available Since

    June 4, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

27. Kv7.4 AB (325-557, Δ 368-523)/pET28HMT

    Plasmid

    #111052

    Purpose

    Protein expression in E.Coli

    Depositor

    Dan Minor

    Article

    Chang et al Neuron. 2018 Feb 21;97(4):836-852.e6. do

    Insert

    potassium voltage-gated channel subfamily KQT member 4 isoform a [Homo sapiens] (KCNQ4 Human)
    

    Tags

    His Tag and MBP tag

    Expression

    Bacterial

    Mutation

    Kv7.4 AB (325-557, Δ 368-523)

    Promoter

    T7

    Available Since

    May 15, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

28. PANK2 gRNA (BRDN0001149459)

    Plasmid

    #76809

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human PANK2

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    PANK2 (PANK2 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

29. SLC30A10-delta105-107

    Plasmid

    #65205

    Purpose

    Constitutive expression of SLC30A10 delta 105-107 in mammalian cells

    Depositor

    Somshuvra Mukhopadhyay

    Article

    Leyva-Illades et al J Neurosci. 2014 Oct 15;34(42):14079-95.

    Insert

    SLC30A10 (SLC30A10 Human)
    

    Tags

    Flag

    Expression

    Mammalian

    Mutation

    delta 105-107 amino acids

    Promoter

    CMV

    Available Since

    May 19, 2015

    Availability

    Academic Institutions and Nonprofits only

30. pENTR-E2F1-PIP3A

    Plasmid

    #37142

    Depositor

    Robert Duronio

    Article

    Shibutani et al Dev Cell. 2008 Dec;15(6):890-900.

    Insert

    E2F1-P!P3A (E2f1 Fly)
    

    Use

    Gateway

    Mutation

    I153, Y156, Y157 to Alanine

    Available Since

    July 9, 2012

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

31. sg_Snrnp48_i1-ipUSEPR-TR657

    Plasmid

    #228925

    Purpose

    Knockdown of Snrnp48 in mammalian cells

    Depositor

    Sika Zheng

    Article

    Lin et al Neuron. 2024 Jul 3;112(13):2157-2176.e12

    Insert

    sg_Snrnp48_i1 (Snrnp48 Mouse)
    

    Use

    Lentiviral

    Available Since

    April 16, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

32. hSyn-HA-PGRN-IRES2-GFP

    Plasmid

    #234876

    Purpose

    Lentiviral plasmid expressing HA-tagged human progranulin followed by IRES2-GFP.

    Depositor

    Andrew Arrant

    Article

    Davis et al J Biol Chem. 2021 Sep;297(3):100993. doi

    Insert

    Progranulin (GRN Human)
    

    Use

    Lentiviral

    Tags

    HA tag

    Expression

    Mammalian

    Promoter

    hSYn

    Available Since

    April 16, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

33. pMXs-uORFx6-mNgn2x3HA-P2A-mRuby2

    Plasmid

    #233168

    Purpose

    Retroviral expression of Ngn2x3HA with mRuby2 fluorescent reporter with upstream open reading frame

    Depositor

    Kate Galloway

    Article

    Wang et al Cell Syst. 2025 Apr 16;16(4):101205. doi

    Insert

    mNgn2x3HA-P2A-mRuby2 (Neurog2 Mouse, Synthetic)
    

    Use

    Retroviral

    Tags

    x3HA

    Expression

    Mammalian

    Available Since

    March 13, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

34. pMXs-uORFwx1-mNgn2x3HA-P2A-mRuby2

    Plasmid

    #233164

    Purpose

    Retroviral expression of Ngn2x3HA with mRuby2 fluorescent reporter with upstream open reading frame

    Depositor

    Kate Galloway

    Article

    Wang et al Cell Syst. 2025 Apr 16;16(4):101205. doi

    Insert

    mNgn2x3HA-P2A-mRuby2 (Neurog2 Mouse, Synthetic)
    

    Use

    Retroviral

    Tags

    x3HA

    Expression

    Mammalian

    Available Since

    March 13, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

35. pMXs-uORFx1-mNgn2x3HA-P2A-mRuby2

    Plasmid

    #233165

    Purpose

    Retroviral expression of Ngn2x3HA with mRuby2 fluorescent reporter with upstream open reading frame

    Depositor

    Kate Galloway

    Article

    Wang et al Cell Syst. 2025 Apr 16;16(4):101205. doi

    Insert

    mNgn2x3HA-P2A-mRuby2 (Neurog2 Mouse, Synthetic)
    

    Use

    Retroviral

    Tags

    x3HA

    Expression

    Mammalian

    Available Since

    March 13, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

36. pMXs-uORFx2-mNgn2x3HA-P2A-mRuby2

    Plasmid

    #233166

    Purpose

    Retroviral expression of Ngn2x3HA with mRuby2 fluorescent reporter with upstream open reading frame

    Depositor

    Kate Galloway

    Article

    Wang et al Cell Syst. 2025 Apr 16;16(4):101205. doi

    Insert

    mNgn2x3HA-P2A-mRuby2 (Neurog2 Mouse, Synthetic)
    

    Use

    Retroviral

    Tags

    x3HA

    Expression

    Mammalian

    Available Since

    March 13, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

37. pMXs-uORFx3-mNgn2x3HA-P2A-mRuby2

    Plasmid

    #233167

    Purpose

    Retroviral expression of Ngn2x3HA with mRuby2 fluorescent reporter with upstream open reading frame

    Depositor

    Kate Galloway

    Article

    Wang et al Cell Syst. 2025 Apr 16;16(4):101205. doi

    Insert

    mNgn2x3HA-P2A-mRuby2 (Neurog2 Mouse, Synthetic)
    

    Use

    Retroviral

    Tags

    x3HA

    Expression

    Mammalian

    Available Since

    March 13, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

38. pPB9P3

    Plasmid

    #210034

    Purpose

    Contains cloning site for PE3/3b prime editing gRNA constructs, inducible prime editor 2, rtTA-T2A-puro

    Depositor

    Michael Talkowski

    Article

    Nuttle et al Cell Rep Methods. 2023 Dec 5:100672. doi

    Inserts

    prime editor 2
    rtta-T2A-puro
    

    Use

    CRISPR

    Tags

    SV40 NLS

    Expression

    Mammalian

    Promoter

    EF-1α and TRE3G

    Available Since

    Feb. 6, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

39. sg_Tada3_i3-ipUSEPR-TR657

    Plasmid

    #228915

    Purpose

    Knockdown of Tada3 in mammalian cells

    Depositor

    Sika Zheng

    Article

    Lin et al Neuron. 2024 Jul 3;112(13):2157-2176.e12

    Insert

    sg_Tada3_i3 (Tada3 Mouse)
    

    Use

    Lentiviral

    Available Since

    Jan. 7, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

40. sg_Tada3_i5-ipUSEPR-TR657

    Plasmid

    #228916

    Purpose

    Knockdown of Tada3 in mammalian cells

    Depositor

    Sika Zheng

    Article

    Lin et al Neuron. 2024 Jul 3;112(13):2157-2176.e12

    Insert

    sg_Tada3_i3 (Tada3 Mouse)
    

    Use

    Lentiviral

    Available Since

    Jan. 7, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

41. sg_Snrnp48_i4-ipUSEPR-TR657

    Plasmid

    #228926

    Purpose

    Knockdown of Snrnp48 in mammalian cell

    Depositor

    Sika Zheng

    Article

    Lin et al Neuron. 2024 Jul 3;112(13):2157-2176.e12

    Insert

    sg_Snrnp48_i4 (Snrnp48 Mouse)
    

    Use

    Lentiviral

    Available Since

    Jan. 7, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

42. pCAG_SRGAP2A_SH3(W765A)_GFP

    Plasmid

    #222616

    Purpose

    Expresses a form of full length SRGAP2 with one point mutation (W765A) in the SH3 domain abrogating its ability to bind to Gephyrin.

    Depositor

    Franck Polleux

    Article

    Fossati et al Neuron. 2016 Jul 20;91(2):356-69. doi: 1

    Insert

    SRGAP2 (SRGAP2 Human)
    

    Tags

    EGFP

    Expression

    Mammalian

    Mutation

    Point mutation W765A (SH3 domain)

    Available Since

    Oct. 9, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

43. pCAG_SRGAP2A_SH3(W765A)_HA

    Plasmid

    #222614

    Purpose

    Expresses a form of full length SRGAP2 with one point mutation (W765A) in the SH3 domain abrogating its ability to bind to Gephyrin.

    Depositor

    Franck Polleux

    Article

    Fossati et al Neuron. 2016 Jul 20;91(2):356-69. doi: 1

    Insert

    SRGAP2 (SRGAP2 Human)
    

    Tags

    HA

    Expression

    Mammalian

    Mutation

    Point mutation W765A (SH3 domain)

    Available Since

    Oct. 9, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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44. pCAG SRGAP2A_EVH1(P339L F342C)

    Plasmid

    #222613

    Purpose

    Expresses a form of full length SRGAP2 with two point mutations (P339L and F342C) that abrogate EVH1 binding site for Homer1

    Depositor

    Franck Polleux

    Article

    Fossati et al Neuron. 2016 Jul 20;91(2):356-69. doi: 1

    Insert

    SRGAP2 (SRGAP2 Human)
    

    Tags

    EGFP

    Expression

    Mammalian

    Mutation

    Point mutations P339L and F342C

    Available Since

    Oct. 9, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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45. pLKO.1 mTagBFP2 rat DJ-1 shRNA

    Plasmid

    #222870

    Purpose

    Expresses mTagBFP2 along with an shRNA against rat DJ-1

    Depositor

    Timothy Ryan

    Article

    Kokotos et al Sci Adv. 2024 Aug 23;10(34):eadn6016. do

    Insert

    DJ-1 shRNA (Park7 Rat)
    

    Use

    Lentiviral and RNAi

    Expression

    Mammalian

    Promoter

    U6

    Available Since

    July 9, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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46. pLKO-Tet-On-ARNT-shRNA1

    Plasmid

    #166910

    Purpose

    Lentivirus for inducible knockdown of human ARNT

    Depositor

    Roland Friedel

    Article

    Halawani et al Nat Commun. 2023 Aug 24;14(1):5165. doi:

    Insert

    ARNT shRNA (ARNT Human)
    

    Use

    Lentiviral

    Expression

    Mammalian

    Available Since

    March 14, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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47. pLKO-Tet-On-ARNT-shRNA2

    Plasmid

    #166911

    Purpose

    Lentivirus for inducible knockdown of human ARNT

    Depositor

    Roland Friedel

    Article

    Halawani et al Nat Commun. 2023 Aug 24;14(1):5165. doi:

    Insert

    ARNT shRNA (ARNT Human)
    

    Use

    Lentiviral

    Expression

    Mammalian

    Available Since

    March 14, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

48. pLKO-Tet-On-ARNT-shRNA3

    Plasmid

    #166912

    Purpose

    Lentivirus for inducible knockdown of human ARNT

    Depositor

    Roland Friedel

    Article

    Halawani et al Nat Commun. 2023 Aug 24;14(1):5165. doi:

    Insert

    ARNT shRNA (ARNT Human)
    

    Use

    Lentiviral

    Expression

    Mammalian

    Available Since

    March 14, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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49. Cav2.1 R57A, R59A pMT2

    Plasmid

    #206112

    Purpose

    expression of rat Cav2.1 calcium channel with R57A and R59A mutations that prevent G-protein modulation

    Depositor

    Annette Dolphin

    Article

    Dahimene et al Neurobiol Dis. 2016 Sep;93:243-56. doi:

    Insert

    cacna1a (Cacna1a Rat)
    

    Expression

    Mammalian

    Mutation

    R57A, R59A

    Promoter

    Ad MLP/TPL/SV40

    Available Since

    Nov. 20, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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50. GFP Cav2.2 D122A pcDNA3

    Plasmid

    #206068

    Purpose

    expression of rabbit Cav2.2 calcium channel with a N-terminal GFP tag and a D122A mutation that disrupts the interaction with ?2?-1

    Depositor

    Annette Dolphin

    Article

    Page et al J Neurosci. 2004 Jun 9;24(23):5400-9. do

    Insert

    cacna1b (CACNA1B Rabbit)
    

    Tags

    GFP

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    Oct. 12, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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