We narrowed to 14,994 results for: GRN

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lentiCRISPRv2-sgRNAs-del-CDK5RAP2-SVA-BFP

Plasmid

#202824

Purpose

Lentiviral vector modified to express two sgRNAs that delete the intronic SVA within the CDK5RAP2 gene with EF-1apha for Cas9 and BFP expression

Depositor

Matthew Anderson

Article

Nadler et al Commun Biol. 2023 Mar 30;6(1):347. doi:

Insert

two sgRNAs (each with a U6 promoter) to delete SVA within CDK5RAP2 gene

Use

Lentiviral

Expression

Mammalian

Promoter

U6 - two

Available Since

July 6, 2023

Availability

Academic Institutions and Nonprofits only

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U6-Slc1a3 sgRNA; EF1a-dCas9-KRAB-GFP

Plasmid

#194283

Purpose

EF1a-dCas9-KRAB-GFP with Slc1a3 sgRNA

Depositor

Elizabeth Kirby

Article

Rieskamp et al iScience. 2023 Jun 8;26(7):107068. doi:

Insert

dCas9-KRAB-GFP

Use

CRISPR and Lentiviral

Tags

GFP

Promoter

EF1a

Available Since

June 14, 2023

Availability

Academic Institutions and Nonprofits only

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pU6-pegRNA-HEK3-CTTins-px330-scaffold

Plasmid

#180017

Purpose

Transiently expressing a pegRNA to introduce HEK3 CTT insertion in human cells. It has a sgRNA scaffold from px330.

Depositor

Dirk Hockemeyer

Article

Li et al Elife. 2022 Sep 7;11:e79208. doi: 10.755

Insert

Prime editing pegRNA for HEK3-CTTins, with px330 scaffold (EPHA8 Synthetic)

Use

CRISPR

Expression

Mammalian

Promoter

Human U6

Available Since

Sept. 8, 2022

Availability

Academic Institutions and Nonprofits only

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pU6-sgRNA EF1Alpha-puro-T2A-BFP.ERH1

Plasmid

#164800

Purpose

For CRISPRi knockdown of ERH by lentiviral delivery of ERH gRNA1

Depositor

David Bartel

Article

Fang et al Mol Cell. 2020 Apr 16;78(2):289-302.e6.

Inserts

ERH CRISPRi gRNA1
puro-T2A-BFP

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

EF1Alpha and U6

Available Since

March 15, 2021

Availability

Academic Institutions and Nonprofits only

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pU6-sgRNA EF1Alpha-puro-T2A-BFP.ERH2

Plasmid

#164801

Purpose

For CRISPRi knockdown of ERH by lentiviral delivery of ERH gRNA2

Depositor

David Bartel

Article

Fang et al Mol Cell. 2020 Apr 16;78(2):289-302.e6.

Inserts

ERH CRISPRi gRNA2
puro-T2A-BFP

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

EF1Alpha and U6

Available Since

March 15, 2021

Availability

Academic Institutions and Nonprofits only

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pLV_mU6-sgASCL1_hU6-sgRNA_hUbC-PuroR-P2A-GFP

Plasmid

#162337

Purpose

Lentiviral expression of sgASCL1 paired with a second S. pyogenes sgRNA with a GFP-P2A-PuroR selection marker

Depositor

Charles Gersbach

Article

Black et al Cell Rep. 2020 Dec 1;33(9):108460. doi:

Insert

S. pyogenes sgRNA

Use

Lentiviral

Expression

Mammalian

Promoter

hU6; mU6

Available Since

Feb. 11, 2021

Availability

Academic Institutions and Nonprofits only

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pLKO.1-puro U6 sgRNA BfuAI stuffer G-tract

Plasmid

#138524

Purpose

Expresses a guide RNA of choice cloned into the BfuI site extended at the 3' end to incorporate a 220-nt PRC2-binding G-tract repeat RNA sequence.

Depositor

Richard Jenner

Article

Beltran et al Nat Struct Mol Biol. 2019 Oct;26(10):899

Insert

PRC2-binding G-tract repeat RNA

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

U6

Available Since

Aug. 5, 2020

Availability

Academic Institutions and Nonprofits only

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pLKO.1-puro-U6-SpyCas9-TLR-MCV1-sgRNA2

Plasmid

#117406

Purpose

SpyCas9 sgRNA 2 targeting TLR2.0

Depositor

Erik Sontheimer

Article

Iyer et al CRISPR J. 2022 Oct;5(5):685-701. doi: 10

Insert

SpyCas9 sgRNA targeting TLR 2.0

Use

Lentiviral

Expression

Mammalian

Promoter

U6

Available Since

Dec. 5, 2019

Availability

Academic Institutions and Nonprofits only

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pU6-sgRNA EF1Alpha-puro-T2A-BFP.CYRANO

Plasmid

#128755

Purpose

Expresses CYRANO gRNA for CRISPRi

Depositor

David Bartel

Article

Kleaveland et al Cell. 2018 Jul 12;174(2):350-362.e17. do

Insert

CYRANO sgRNA (OIP5-AS1 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

mU6

Available Since

Aug. 14, 2019

Availability

Academic Institutions and Nonprofits only

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PX330-TH-sgRNA-1

Plasmid

#247673

Purpose

All-in-one CRISPR construct targeting TH

Depositor

Ellen Sidransky

Article

Hertz et al Mov Disord. 2025 Aug;40(8):1719-1724. do

Insert

TH sgRNA 1 (TH Human)

Use

CRISPR

Expression

Mammalian

Available Since

June 3, 2026

Availability

Academic Institutions and Nonprofits only

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PX330-TH-sgRNA-2

Plasmid

#247674

Purpose

All-in-one CRISPR construct targeting TH

Depositor

Ellen Sidransky

Article

Hertz et al Mov Disord. 2025 Aug;40(8):1719-1724. do

Insert

TH sgRNA 2 (TH Human)

Use

CRISPR

Expression

Mammalian

Available Since

June 3, 2026

Availability

Academic Institutions and Nonprofits only

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pAT15535_hU6_epegRNA_Ef1a-mCh

Plasmid

#251104

Purpose

epegRNA cloning plasmid + mCherry expression

Depositor

Gerald Schwank

Article

Talas et al Sci Transl Med. 2026 May 13;18(849):eaec

Insert

pegRNA cloning vector

Use

CRISPR

Available Since

May 14, 2026

Availability

Academic Institutions and Nonprofits only

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pAT159_AAV_p3_PE7-C_hU6_epegRNA

Plasmid

#251105

Purpose

Encodes the C terminal of the PE7 prime editor in an AAV expression plasmid + pegRNA cloning casette

Depositor

Gerald Schwank

Article

Talas et al Sci Transl Med. 2026 May 13;18(849):eaec

Insert

PE7 C-terminal

Use

AAV and CRISPR

Promoter

p3

Available Since

May 14, 2026

Availability

Academic Institutions and Nonprofits only

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pLentiCRISPRv2_mPTK7-gRNA4

Plasmid

#249199

Purpose

mouse PTK7 CRISPR KO

Depositor

Weihong Tan

Article

Luo et al Science. 2026 Jan;391(6780):eadv6127. do

Insert

PTK7 (Ptk7 Mouse)

Use

CRISPR and Lentiviral

Promoter

U6

Available Since

April 15, 2026

Availability

Academic Institutions and Nonprofits only

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pLentiCRISPRv2_hPTK7-gRNA2

Plasmid

#249197

Purpose

human PTK7 CRISPR KO

Depositor

Weihong Tan

Article

Luo et al Science. 2026 Jan;391(6780):eadv6127. do

Insert

PTK7 (PTK7 Human)

Use

CRISPR and Lentiviral

Promoter

U6

Available Since

April 15, 2026

Availability

Academic Institutions and Nonprofits only

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sgRNA(nt)-IM83

Plasmid

#251969

Purpose

Control sgRNA with IM83 aptamer for yeast mtDNA editing

Depositor

Alice Ting

Article

Yin et al Proc Natl Acad Sci U S A. 2026 Jan 20;12

Insert

sgRNA(nt)-IM83

Use

CRISPR

Expression

Yeast

Promoter

SNR52

Available Since

March 30, 2026

Availability

Academic Institutions and Nonprofits only

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sgRNA-IM83

Plasmid

#251967

Purpose

sgRNA with IM83 aptamer for yeast mtDNA editing

Depositor

Alice Ting

Article

Yin et al Proc Natl Acad Sci U S A. 2026 Jan 20;12

Insert

sgRNA-IM83

Use

CRISPR

Expression

Yeast

Promoter

SNR52

Available Since

March 18, 2026

Availability

Academic Institutions and Nonprofits only

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sgRNA-msIM83

Plasmid

#251968

Purpose

sgRNA for yeast mtDNA editing, with IM83 aptamer inserted into the major stem-loop of the sgRNA

Depositor

Alice Ting

Article

Yin et al Proc Natl Acad Sci U S A. 2026 Jan 20;12

Insert

sgRNA-msIM83

Use

CRISPR

Expression

Yeast

Promoter

SNR52

Available Since

March 18, 2026

Availability

Academic Institutions and Nonprofits only

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IR InterIR gRNA #5

Plasmid

#247547

Purpose

negative control for Crispri KD

Depositor

Miguel Ramalho-Santos

Article

Ataei et al Genes Dev. 2025 Feb 3;39(3-4):280-298. d

Insert

negative control sgRNA targeting region between inverted repeats of Distal Junction

Use

CRISPR

Expression

Mammalian

Mutation

none

Available Since

March 16, 2026

Availability

Academic Institutions and Nonprofits only

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InterIR gRNA #2

Plasmid

#247546

Purpose

negative control for Crispri KD

Depositor

Miguel Ramalho-Santos

Article

Ataei et al Genes Dev. 2025 Feb 3;39(3-4):280-298. d

Insert

negative control sgRNA targeting region between inverted repeats of Distal Junction

Use

CRISPR

Expression

Mammalian

Mutation

none

Available Since

March 16, 2026

Availability

Academic Institutions and Nonprofits only

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