We narrowed to 5,207 results for: Apoe;

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PIK3CA gRNA (BRDN0001146906)

Plasmid

#77417

Purpose

3rd generation lentiviral gRNA plasmid targeting human PIK3CA

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

PIK3CA (PIK3CA Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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pENTR221-BCL2

Plasmid

#251695

Purpose

Gateway-adapted BCL2 ORF

Depositor

Boyi Gan

Article

Lei et al Cancer Cell. 2025 Jun 9;43(6):1076-1092.

Insert

BCL2 BCL2 apoptosis regulator (BCL2 Human)

Use

Gateway donor vector

Available Since

Feb. 23, 2026

Availability

Academic Institutions and Nonprofits only

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pL(CMVtight-phi-AQP1-FKBP12DD-IRES-EGFP-WPRE)

Plasmid

#236278

Purpose

Lentiviral vector that can express doxycycline-inducible hAqp1 with fkbp12 degron in Tet ON mammalian cells. CMVtight promoter. EGFP marker.

Depositor

Arnab Mukherjee

Article

Yun et al Chem Sci. 2024 Jun 4;15(28):11108-11121.

Insert

human aquaporin 1 (AQP1 Human)

Use

Lentiviral

Tags

Flag and fkbp12

Expression

Mammalian

Promoter

CMVtight

Available Since

June 3, 2025

Availability

Academic Institutions and Nonprofits only

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pDV18 [punc-47::SNG-1::CRY2olig(535)]

Plasmid

#197598

Purpose

Expression of SNG-1::CRY2olig(535) in GABAergic motor neurons of C. elegans

Depositor

Alexander Gottschalk

Article

Vettkotter et al Nat Commun. 2022 Dec 19;13(1):7827. doi:

Insert

Synaptogyrin-CRY2 (E490G + residues 1-535) (CRY2, sng-1 Mustard Weed, Nematode)

Expression

Worm

Mutation

E490G

Available Since

July 10, 2024

Availability

Academic Institutions and Nonprofits only

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pDV12 [psng-1::SNG-1::CRY2olig(535)]

Plasmid

#197596

Purpose

Pan-neuronal expression of SNG-1::CRY2olig(535) in neurons of C. elegans

Depositor

Alexander Gottschalk

Article

Vettkotter et al Nat Commun. 2022 Dec 19;13(1):7827. doi:

Insert

Synaptogyrin-CRY2 (E490G + residues 1-535) (CRY2, sng-1 Mustard Weed, Nematode)

Expression

Worm

Mutation

E490G

Available Since

July 10, 2024

Availability

Academic Institutions and Nonprofits only

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pKM 1995

Plasmid

#217826

Purpose

Expresses 1554 bp fragment of HY4 gene in A. thaliana. This HY4 fragment shows high homology to the phr genes in prokaryotes.

Depositor

Aziz Sancar

Article

Malhotra et al Biochemistry. 1995 May 23;34(20):6892-9.

Insert

HY4 (CRY1 Mustard Weed)

Tags

Maltose-binding protein

Expression

Bacterial

Available Since

June 6, 2024

Availability

Academic Institutions and Nonprofits only

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pCMV-enCas12a-A3A-N57G

Plasmid

#193651

Purpose

Expression of base editor enCas12a-A3A-N57G in mammalian cells for base editing, along with non-fused EGFP fluorescence

Depositor

Liangxue Lai

Article

Chen et al Commun Biol. 2022 Nov 2;5(1):1163. doi:

Insert

dLb-enCas12a-hA3A-N57G, EGFP

Expression

Mammalian

Mutation

dLbCas12a-D156R/G532R/K538R, hAPOBEC3A-N57G

Promoter

CMV

Available Since

Feb. 20, 2024

Availability

Academic Institutions and Nonprofits only

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pDV06 [punc-17::SNG-1::CRY2(535)]

Plasmid

#197597

Purpose

Expression of SNG-1::CRY2olig(535) in cholinergic motor neurons of C. elegans

Depositor

Alexander Gottschalk

Article

Vettkotter et al Nat Commun. 2022 Dec 19;13(1):7827. doi:

Insert

Synaptogyrin-CRY2 (E490G + residues 1-535) (CRY2, sng-1 Mustard Weed, Nematode)

Expression

Worm

Mutation

E490G

Available Since

Dec. 15, 2023

Availability

Academic Institutions and Nonprofits only

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pLVX-DmrB-Casp8-2A-mCherry-puro

Plasmid

#231971

Purpose

Tet inducible expression of DmrB-Casp8 with mCherry to induce Casp8 apoptosis

Depositor

Brian Ruffell

Article

Hanggi et al Cancer Cell. 2024 Nov 13:S1535-6108(24)0

Insert

Casp8 dimerizing construct with bi-cistronic mCherry (CASP8 Human)

Use

Lentiviral

Available Since

Feb. 5, 2025

Availability

Academic Institutions and Nonprofits only

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hKCNQ5(WT).ires.GFP-pcDNA3

Plasmid

#204360

Purpose

Heterologous expression in mammalian cell lines or Xenopus oocyte (T7 RNA pol)

Depositor

Aguan Wei

Article

Wei et al J Neurophysiol. 2022 Jul 1;128(1):40-61.

Insert

KCNQ5 (KCNQ5 Human)

Expression

Mammalian

Promoter

CMV/T7 RNApol

Available Since

Aug. 21, 2023

Availability

Academic Institutions and Nonprofits only

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pPHR-mCherry-hPMLIII

Plasmid

#103824

Purpose

Soluble BLInCR effector that is recruited to 'localizer' sites upon blue light illumination

Depositor

Karsten Rippe

Article

Rademacher et al J Cell Sci. 2017 Dec 15;130(24):4213-422

Insert

PHR-mCherry-hPMLIII (CRY2, PML Human, Mustard Weed)

Expression

Mammalian

Promoter

CMV

Available Since

Dec. 1, 2017

Availability

Academic Institutions and Nonprofits only

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pHAGE-PIK3CA

Plasmid

#116771

Purpose

Lentiviral expression of PIK3CA

Depositor

Gordon Mills, Kenneth Scott

Article

Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

Insert

PIK3CA (PIK3CA Human)

Use

Lentiviral

Mutation

WT

Available Since

March 14, 2019

Availability

Academic Institutions and Nonprofits only

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pRSITEP-shBIRC6-2

Plasmid

#202449

Purpose

DOX-inducible expression of a short-hairpin RNA targetinging human BIRC6

Depositor

William Hahn

Article

Cervia et al Cancer Discov. 2023 Mar 1;13(3):766-795.

Insert

BIRC6 shRNA (BIRC6 Human)

Use

Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

June 29, 2023

Availability

Academic Institutions and Nonprofits only

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hKCNQ3(WT).ires.mCherry-pcDNA3

Plasmid

#204362

Purpose

Heterologous expression in mammalian cell lines or Xenopus oocyte (T7 RNA pol)

Depositor

Aguan Wei

Article

Wei et al J Neurophysiol. 2022 Jul 1;128(1):40-61.

Insert

KCNQ3 (KCNQ3 Human)

Expression

Mammalian

Promoter

CMV/T7 RNApol

Available Since

Aug. 21, 2023

Availability

Academic Institutions and Nonprofits only

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CRY2high-mCherry-Raf1

Plasmid

#104064

Purpose

Expresses fusion of CRY2high mutant (CRY2PHR E490R) with mCherry and Raf1

Depositor

Bianxiao Cui

Article

Duan et al Nat Commun. 2017 Sep 15;8(1):547. doi: 1

Insert

CRY2high-mCherry-Raf1 (CRY2, RAF1 Human, Mustard Weed)

Expression

Mammalian

Mutation

CRY2PHR E490R

Promoter

CMV

Available Since

Dec. 19, 2017

Availability

Academic Institutions and Nonprofits only

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pAAV-CAG-mCherry-Tandem-PSAM4-GlyR

Plasmid

#208361

Purpose

Expression of the inhibitory chemogenetic tool PSAM4-GlyR and mCherry reporter. Application of ultrapotent agonists induces neuronal silencing.

Depositor

David Bennett

Article

Perez-Sanchez et al Sci Transl Med. 2023 Oct 4;15(716):eadh3

Insert

mCherry-TANDEM-PSAM4-GlyR

Use

AAV

Tags

mCherry

Expression

Mammalian

Promoter

CAG

Available Since

Oct. 13, 2023

Availability

Academic Institutions and Nonprofits only

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hKCNQ5(WT).ires.mScarlet-pcDNA3

Plasmid

#204361

Purpose

Heterologous expression in mammalian cell lines or Xenopus oocyte (T7 RNA pol)

Depositor

Aguan Wei

Article

Wei et al J Neurophysiol. 2022 Jul 1;128(1):40-61.

Insert

KCNQ5 (KCNQ5 Human)

Expression

Mammalian

Promoter

CMV/T7 RNApol

Available Since

Aug. 21, 2023

Availability

Academic Institutions and Nonprofits only

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hBACE1(D289N).ires.mCherry-pcDNA3

Plasmid

#204363

Purpose

Heterologous expression in mammalian cell lines or Xenopus oocyte (T7 RNA pol)

Depositor

Aguan Wei

Article

Wei et al J Neurophysiol. 2022 Jul 1;128(1):40-61.

Insert

BACE1 (BACE1 Human)

Expression

Mammalian

Mutation

D289N

Promoter

CMV/T7 RNApol

Available Since

Aug. 21, 2023

Availability

Academic Institutions and Nonprofits only

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Venus-Bad-4E-pEGFP-C1

Plasmid

#166740

Purpose

Express Venus fused to the N-terminus of the Bcl-2 family protein, Bad with mutation in BH3 domain to disrupt binding anti-apoptotic proteins

Depositor

David Andrews

Article

Liu et al Elife. 2019 Mar 12;8. pii: 37689. doi: 1

Insert

Bad-4E (BAD Human)

Tags

Venus

Expression

Mammalian

Mutation

4 hydrophobic residues in the BH3 region mutated …

Promoter

CMV

Available Since

March 30, 2021

Availability

Academic Institutions and Nonprofits only

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nCas9-UGI-NLS-P2A-EGFP (pJUL1001)

Plasmid

#123611

Purpose

CAG promoter expression plasmid for hSpCas9n(D10A)-UGI-NLS(SV40)-P2A-EGFP (BE3 control without rAPOBEC1).

Depositor

Keith Joung

Article

Grunewald et al Nature. 2019 Apr 17. pii: 10.1038/s41586

Insert

nCas9-UGI-NLS-P2A-EGFP

Expression

Mammalian

Mutation

D10A in SpCas9

Promoter

CAG

Available Since

April 17, 2019

Availability

Academic Institutions and Nonprofits only

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