We narrowed to 8,688 results for: App

1. pKK-RNAi-nucCHERRYmiR-TEV-EGFP

   Plasmid

   #105814

   Purpose

   Functional studies using RNAi; rescue experiments; substituting protein for its different form. miRNA cassette with nuclear mCherry expression marker; your protein of interest with C-terminal EGFP.

   Depositor

   Andrzej Dziembowski

   Article

   Szczesny et al PLoS One. 2018 Mar 28;13(3):e0194887. do

   Type

   Empty backbone

   Use

   RNAi; Flp-in competent

   Tags

   TEV-EGFP

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   Feb. 12, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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2. pTWIN1-His6-Ssp-Htt2-90(A2C)-37Q

   Plasmid

   #114617

   Purpose

   Bacterial expression of Htt fragment containing amino acids 2-90, with A2C cysteine mutation and a 37 polyQ repeat

   Depositor

   Hilal Lashuel

   Article

   Warner JB et al J Am Chem Soc. 2017 Oct 18;139(41):14456

   Insert

   Huntingtin Exon1 fragment (HTT Human)
   

   Use

   Tags

   His6-Ssp DnaB intein

   Expression

   Bacterial

   Mutation

   A2C; 23 polyQ repeat

   Promoter

   Available since

   Oct. 5, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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3. pTWIN1-His6-Ssp-Httex1-43Q-A2C

   Plasmid

   #114622

   Purpose

   Bacterial expression of Htt fragment containing exon 1, with A2C cysteine mutation and a 43 polyQ repeat

   Depositor

   Hilal Lashuel

   Article

   Warner JB et al J Am Chem Soc. 2017 Oct 18;139(41):14456

   Insert

   Huntingtin Exon1 (HTT Human)
   

   Use

   Tags

   His6-Ssp DnaB intein

   Expression

   Bacterial

   Mutation

   A2C; 43 polyQ repeat

   Promoter

   Available since

   Sept. 18, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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4. pTWIN1-His6-Ssp-Httex1-43Q-A2C-A60C

   Plasmid

   #114623

   Purpose

   Bacterial expression of Htt fragment containing exon 1, with A2C & A60C cysteine mutations and a 43 polyQ repeat

   Depositor

   Hilal Lashuel

   Article

   Warner JB et al J Am Chem Soc. 2017 Oct 18;139(41):14456

   Insert

   Huntingtin Exon1 (HTT Human)
   

   Use

   Tags

   His6-Ssp DnaB intein

   Expression

   Bacterial

   Mutation

   A2C, A60C; 43 polyQ repeat

   Promoter

   Available since

   Sept. 19, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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5. pTWIN1-His6-Ssp-Htt2-90(A2C)-49Q

   Plasmid

   #114627

   Purpose

   Bacterial expression of Htt fragment containing amino acids 2-90, with A2C cysteine mutation and a 49 polyQ repeat

   Depositor

   Hilal Lashuel

   Article

   Warner JB et al J Am Chem Soc. 2017 Oct 18;139(41):14456

   Insert

   Huntingtin Exon1 fragment (HTT Human)
   

   Use

   Tags

   His6-Ssp DnaB intein

   Expression

   Bacterial

   Mutation

   A2C; 49 polyQ repeat

   Promoter

   Available since

   Sept. 19, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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6. pTWIN1-His6-Ssp-Htt2-90-49Q-P90C

   Plasmid

   #114631

   Purpose

   Bacterial expression of Htt fragment containing amino acids 2-90, with P90C cysteine mutation and a 49 polyQ repeat

   Depositor

   Hilal Lashuel

   Article

   Warner JB et al J Am Chem Soc. 2017 Oct 18;139(41):14456

   Insert

   Huntingtin Exon1 fragment (HTT Human)
   

   Use

   Tags

   His6-Ssp DnaB intein

   Expression

   Bacterial

   Mutation

   P90C; 49 polyQ repeat

   Promoter

   Available since

   Sept. 18, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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7. MSCV-NSD3-short del(100-263)

   Plasmid

   #72548

   Purpose

   expresses 3*FLAG tagged human NSD3-short with 100-263 aa deletion

   Depositor

   Christopher Vakoc

   Article

   Shen et al Mol Cell. 2015 Nov 24. pii: S1097-2765(1

   Insert

   NSD3-short (NSD3 Human)
   

   Use

   Retroviral

   Tags

   3xFlag and SV40 NLS

   Expression

   Mammalian

   Mutation

   100-263 aa deletion

   Promoter

   LTR

   Available since

   Jan. 20, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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8. p5E-hs_UbiC-pro (JDW 1461)

   Plasmid

   #242547

   Purpose

   Enhancer/Promoter: Gateway 5' entry vector containing human Ubc promoter (-1225 to -6)

   Depositor

   Joshua Wythe

   Article

   Gillespie et al bioRxiv [Preprint]. 2024 Jul 13:2024.07.

   Insert

   Ubiquitin / Ubc promoter (UBC Human)
   

   Use

   Gateway subcloning

   Tags

   Expression

   Mutation

   Promoter

   Available since

   Sept. 11, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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9. Mirror GFP[ENE(WT)-mascRNA(mut 8356-8370)](pAVA3874)

   Plasmid

   #239353

   Purpose

   Expresses TEV protease and tandemly-repeated GFP fluorescent proteins to amplify the fluorescence signal produced by a single transcription unit of MALAT1 ENE(WT)-mascRNA(mut 8356-8370) reporter.

   Depositor

   Andrei Alexandrov

   Article

   Che et al Nat Commun. 2025 May 22;16(1):4741. doi:

   Insert

   MALAT1 ENE(WT)-mascRNA(mut 8356-8370)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   MALAT1 ENE(WT)-mascRNA(mut 8356-8370: ctacgaccacc…

   Promoter

   Available since

   Aug. 26, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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10. LentiCRISPR-B_2xsgRNAs_RPP21 (pAVA3259)

    Plasmid

    #239327

    Purpose

    Lentiviral vector expressing Cas9-P2A-Blasticidin and two sgRNAs targeting RPP21

    Depositor

    Andrei Alexandrov

    Article

    Che et al Nat Commun. 2025 May 22;16(1):4741. doi:

    Insert

    U6-driven sgRNA1 and 7SK-driven sgRNA2 targeting RPP21 (RPP21 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available since

    Aug. 11, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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11. pRCA893 - pBA904 Puro-T2A-BFP KLF5 g1 CRISPRa guide guide (pRCA594 backbone) 666

    Plasmid

    #238186

    Purpose

    Lentiviral CRISPR guide vector expressing a KLF5 sgRNA with cs1 incorporated in the loop of the sgRNA constant region for 10X Direct Capture

    Depositor

    Thomas Norman

    Article

    Southard et al Nat Genet. 2025 Aug 6. doi: 10.1038/s415

    Insert

    KLF5 sgRNA CRISPRa (KLF5 Human, Synthetic)
    

    Use

    CRISPR and Lentiviral

    Tags

    mTagBFP2

    Expression

    Mutation

    Promoter

    Available since

    Aug. 6, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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12. LentiCRISPR-B_2xsgRNAs_BRF2 (pAVA3258)

    Plasmid

    #239326

    Purpose

    Lentiviral vector expressing Cas9-P2A-Blasticidin and two sgRNAs targeting BRF2

    Depositor

    Andrei Alexandrov

    Article

    Che et al Nat Commun. 2025 May 22;16(1):4741. doi:

    Insert

    U6-driven sgRNA1 and 7SK-driven sgRNA2 targeting BRF2 (BRF2 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available since

    Aug. 4, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

13. TCTN3 minigene (pAVA3939)

    Plasmid

    #239345

    Purpose

    Expresses TCTN3 minigene (EFS-6xMyc-TCTN3-Ex10-I10-Ex11-copGFP-3xFLAG)

    Depositor

    Andrei Alexandrov

    Article

    Che et al Nat Commun. 2025 May 22;16(1):4741. doi:

    Insert

    EFS-6xMyc-TCTN3-Ex10-I10-Ex11-copGFP-3xFLAG-BGH polyA (TCTN3 Human)
    

    Use

    Tags

    3xFLAG, 6xMyc, and CopGFP

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Aug. 4, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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14. pcDNA5/FRT/MALAT1[C8351G] (pAVA3169)

    Plasmid

    #239346

    Purpose

    Expresses full-length, driven by its own promoter MALAT1 with stability-compromised ENE(C8351G) and an 11-nt insertion (cgctcgacgta).

    Depositor

    Andrei Alexandrov

    Article

    Che et al Nat Commun. 2025 May 22;16(1):4741. doi:

    Insert

    10,843 bp of MALAT1 of genomic locus amplified from genomic DNA of Hela cells (MALAT1 Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    An 11-nt insertion (cgctcgacgta) and stability-co…

    Promoter

    Available since

    Aug. 4, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. LentiCRISPR-B_sgRNA_EXOSC6 (pP18(T)_B11-AVA4069)

    Plasmid

    #239304

    Purpose

    Lentiviral vector expressing Cas9-P2A-Blasticidin and an sgRNA targeting EXOSC6

    Depositor

    Andrei Alexandrov

    Article

    Che et al Nat Commun. 2025 May 22;16(1):4741. doi:

    Insert

    U6-driven sgRNA targeting EXOSC6 (EXOSC6 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available since

    Aug. 4, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. LentiCRISPR-B_sgRNA_EXOSC7 (pP18(T)_C4-AVA4066)

    Plasmid

    #239305

    Purpose

    Lentiviral vector expressing Cas9-P2A-Blasticidin and an sgRNA targeting EXOSC7

    Depositor

    Andrei Alexandrov

    Article

    Che et al Nat Commun. 2025 May 22;16(1):4741. doi:

    Insert

    U6-driven sgRNA targeting EXOSC7 (EXOSC7 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available since

    Aug. 4, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. LentiCRISPR-B_sgRNA_EXOSC8 (pP18(T)_B1-AVA4071)

    Plasmid

    #239306

    Purpose

    Lentiviral vector expressing Cas9-P2A-Blasticidin and an sgRNA targeting EXOSC8

    Depositor

    Andrei Alexandrov

    Article

    Che et al Nat Commun. 2025 May 22;16(1):4741. doi:

    Insert

    U6-driven sgRNA targeting EXOSC8 (EXOSC8 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available since

    Aug. 4, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. LentiCRISPR-B_sgRNA_EXOSC9 (pP18(T)_A7-AVA4072)

    Plasmid

    #239307

    Purpose

    Lentiviral vector expressing Cas9-P2A-Blasticidin and an sgRNA targeting EXOSC9

    Depositor

    Andrei Alexandrov

    Article

    Che et al Nat Commun. 2025 May 22;16(1):4741. doi:

    Insert

    U6-driven sgRNA targeting EXOSC9 (EXOSC9 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available since

    Aug. 4, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. LentiCRISPR-B_sgRNA_DIS3 (pP18(T)_A5-AVA4073)

    Plasmid

    #239308

    Purpose

    Lentiviral vector expressing Cas9-P2A-Blasticidin and an sgRNA targeting DIS3

    Depositor

    Andrei Alexandrov

    Article

    Che et al Nat Commun. 2025 May 22;16(1):4741. doi:

    Insert

    U6-driven sgRNA targeting DIS3 (DIS3 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available since

    Aug. 4, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. LentiCRISPR-B_2xsgRNAs_RBM7 (pAVA3250)

    Plasmid

    #239322

    Purpose

    Lentiviral vector expressing Cas9-P2A-Blasticidin and two sgRNAs targeting RBM7

    Depositor

    Andrei Alexandrov

    Article

    Che et al Nat Commun. 2025 May 22;16(1):4741. doi:

    Insert

    U6-driven sgRNA1 and 7SK-driven sgRNA2 targeting RBM7 (RBM7 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available since

    Aug. 4, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge