We narrowed to 29,389 results for: des.2

1. Lsg-GBA-1 + 2

   Plasmid

   #199276

   Purpose

   nicking sgRNA to induce or correct GBA (c. 1226 A > G) mutation using PE3

   Depositor

   Ting Zhou

   Article

   Li et al Nat Commun. 2022 Oct 27;13(1):6354. doi:

   Insert

   GBA nick
   

   Expression

   Mammalian

   Available Since

   April 13, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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2. human MMP-2 promoter

   Plasmid

   #53432

   Purpose

   promoter activity study

   Depositor

   Etty Benveniste

   Article

   Qin et al J Biol Chem. 1999 Oct 8;274(41):29130-7.

   Insert

   MMP2 promoter (MMP2 Human)
   

   Use

   Luciferase

   Tags

   luciferase

   Expression

   Mammalian

   Promoter

   MMP2

   Available Since

   June 2, 2014

   Availability

   Academic Institutions and Nonprofits only

   

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3. AB.pCCL.sin.cPPT.GFP.miR-218-2-3p.sensor.PGK.dNGFR.WPRE

   Plasmid

   #85881

   Purpose

   Sensor Plasmid

   Depositor

   Brian Brown

   Article

   Mullokandov et al Nat Methods. 2012 Jul 1;9(8):840-6. doi:

   Insert

   miR-218-2-3p Sensor (MIR218-2 Human)
   

   Use

   Lentiviral

   Promoter

   PGK

   Available Since

   Jan. 11, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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4. 3336 pcDNA3 Bcl-2

   Plasmid

   #8768

   Depositor

   Stanley Korsmeyer

   Article

   Yamamoto et al Mol Cell Biol 1999 Dec;19(12):8469-78.

   Insert

   Bcl-2 (BCL2 Human)
   

   Expression

   Mammalian

   Available Since

   Nov. 14, 2005

   Availability

   Academic Institutions and Nonprofits only

   

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5. p2Flag CMV2-ZO-2

   Plasmid

   #27415

   Depositor

   Marius Sudol

   Article

   Oka et al Biochem J. 2010 Nov 25. 432(3):461-72.

   Insert

   Zonula Occludens 2 (TJP2 Human)
   

   Tags

   2xFlag

   Expression

   Mammalian

   Available Since

   March 15, 2011

   Availability

   Academic Institutions and Nonprofits only

6. pFYF1327 EGFP Site#2

   Plasmid

   #47512

   Purpose

   human gRNA expression vector targeting EGFP

   Depositor

   Keith Joung

   Article

   Fu et al Nat Biotechnol. 2013 Jun 23. doi: 10.103

   Insert

   gRNA-EGFP site 2
   

   Use

   CRISPR

   Expression

   Mammalian

   Promoter

   U6

   Available Since

   Aug. 29, 2013

   Availability

   Academic Institutions and Nonprofits only

   

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7. pLG018 (AVAST type 2)

   Plasmid

   #157896

   Purpose

   Expresses the AVAST type 2 defense system

   Depositor

   Feng Zhang

   Article

   Gao et al Science. 2020 Aug 28;369(6507):1077-1084

   Insert

   AVAST type 2 (STAND ATPase with uncharacterized helical N-terminal domain)
   

   Expression

   Bacterial

   Available Since

   Dec. 17, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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8. E47 2/5-pCS2

   Plasmid

   #20914

   Depositor

   Stephen Tapscott

   Article

   Yang et al Genes Dev. 2009 Mar 15. 23(6):694-707.

   Insert

   E47 2/5 (TCF3 Human)
   

   Expression

   Mammalian

   Available Since

   April 28, 2009

   Availability

   Academic Institutions and Nonprofits only

9. pCMV-NHERF1-PDZ1-2

   Plasmid

   #28294

   Depositor

   Maria-Magdalena Georgescu

   Article

   Morales et al Mol Cell Biol. 2007 Apr . 27(7):2527-37.

   Insert

   NHERF1 (NHERF1 Human)
   

   Tags

   FLAG

   Expression

   Mammalian

   Mutation

   Contains aa 1-298 (deletion of the EB domain aa 2…

   Available Since

   Sept. 14, 2011

   Availability

   Academic Institutions and Nonprofits only

10. Fluorescent reporter for MOBE1-2

    Plasmid

    #219945

    Purpose

    Mammalian expression of 2x-deadEGFP(A111V/L202S) and aptamer-gRNAs to correct both mutations for MOBE1-2

    Depositor

    Alexis Komor

    Article

    Cowan et al Nat Biotechnol. 2024 May 21. doi: 10.103

    Insert

    CMV-EGFP(A111V/L202S); U6-A111V-gRNA-com-3'end; U6-L202S-gRNA-MS2-3'end
    

    Use

    CRISPR

    Expression

    Mammalian

    Mutation

    EGFP(A111V/L202S)

    Promoter

    CMV, U6

    Available Since

    June 6, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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11. 1/2-NORAD-(A)4x

    Plasmid

    #199208

    Purpose

    1/2 truncation of NORAD mRNA tagged with 4 copies of Riboglow (variant A)

    Depositor

    Esther Braselmann

    Article

    Sarfraz et al Nat Commun. 2023 Feb 16;14(1):867. doi:

    Insert

    1/2-NORAD
    

    Tags

    Riboglow RNA tag

    Expression

    Mammalian

    Mutation

    4 copies of Riboglow tag after stop codon

    Promoter

    CMV

    Available Since

    June 29, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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12. GLI-3 bs-2

    Plasmid

    #16420

    Depositor

    Bert Vogelstein

    Article

    Kinzler et al Nature. 1988 Mar 24. 332(6162):371-4.

    Insert

    GLI3 (GLI3 Human)
    

    Expression

    Bacterial

    Available Since

    March 10, 2008

    Availability

    Academic Institutions and Nonprofits only

13. ZE45 Dvl-2 pCS2P+

    Plasmid

    #17086

    Depositor

    Randall Moon

    Article

    Waxman et al Development. 2004 Dec. 131(23):5909-21.

    Insert

    Dvl-2 (dvl2 Zebrafish)
    

    Use

    Zebrafish expression

    Available Since

    Feb. 1, 2008

    Availability

    Academic Institutions and Nonprofits only

14. pSicoR human DGCR8-2

    Plasmid

    #14770

    Depositor

    Tyler Jacks

    Article

    Kumar et al Nat Genet. 2007 May;39(5):673-7. doi: 10

    Insert

    DGCR8 shRNA (DGCR8 Human)
    

    Use

    Cre/Lox, Lentiviral, and RNAi

    Expression

    Mammalian

    Available Since

    April 5, 2007

    Availability

    Academic Institutions and Nonprofits only

15. pRS-puro shNEDD4L #2

    Plasmid

    #27017

    Depositor

    Joan Massague

    Article

    Gao et al Mol Cell. 2009 Nov 13. 36(3):457-68.

    Insert

    shRNA NEDD4L #2 (NEDD4L Human)
    

    Use

    RNAi and Retroviral

    Expression

    Mammalian

    Available Since

    Dec. 17, 2010

    Availability

    Academic Institutions and Nonprofits only

16. psiCHECK-2 3xmiR-122T

    Plasmid

    #35672

    Depositor

    Phillip Zamore

    Article

    Xie et al Nat Methods. 2012 Mar 4;9(4):403-9. doi:

    Insert

    3 miR-122 target sites
    

    Use

    Luciferase

    Promoter

    HSV-TK

    Available Since

    April 13, 2012

    Availability

    Academic Institutions and Nonprofits only

    

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17. Lsg-LMNA-1 + 2

    Plasmid

    #199278

    Purpose

    nicking sgRNA to induce LMNA (c.1824C > T) mutation using PE3

    Depositor

    Ting Zhou

    Article

    Li et al Nat Commun. 2022 Oct 27;13(1):6354. doi:

    Insert

    LMNA nick
    

    Expression

    Mammalian

    Available Since

    April 13, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. E12 2/5-pCS2

    Plasmid

    #20913

    Depositor

    Stephen Tapscott

    Article

    Yang et al Genes Dev. 2009 Mar 15. 23(6):694-707.

    Insert

    E12 2/5 (TCF3 Human)
    

    Expression

    Mammalian

    Available Since

    April 28, 2009

    Availability

    Academic Institutions and Nonprofits only

19. lentiCRISPR - DDX3Y sgRNA 2

    Plasmid

    #70657

    Purpose

    Expresses human codon-optimized Cas9 protein and puromycin resistance from EFS promoter and a DDX3Y targeting synthetic single-guide RNA (sgRNA) element from U6 promoter. Lentiviral backbone.

    Depositor

    David Sabatini

    Article

    Wang et al Science. 2015 Oct 15. pii: aac7041.

    Insert

    sgRNA against DDX3Y
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Available Since

    Oct. 29, 2015

    Availability

    Academic Institutions and Nonprofits only

20. human syndecan 2 EFYA

    Plasmid

    #64971

    Purpose

    Constitutive expression in mammalian cells

    Depositor

    Enric Espel

    Article

    Rovira-Clave et al Cell Signal. 2014 Jul;26(7):1489-99. doi

    Insert

    syndecan 2 (SDC2 Human)
    

    Expression

    Mammalian

    Mutation

    deleted EFYA

    Promoter

    CMV

    Available Since

    June 5, 2015

    Availability

    Academic Institutions and Nonprofits only