We narrowed to 29,389 results for: des.2

1. LentiCas9-sgCh2-2-Blast

   Plasmid

   #199645

   Purpose

   Expresses Cas9 and sgRNA control guide targeting intergenic region

   Depositor

   William Hahn

   Article

   So et al JCI Insight. 2022 Oct 10;7(19):e158755.

   Insert

   N/A
   

   Use

   Lentiviral

   Available Since

   May 24, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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2. shMEK1/2 v2 neo

   Plasmid

   #72570

   Purpose

   Hairpin targeting MEK1 and MEK2 (murine).

   Depositor

   Kevin Janes

   Article

   Jensen et al Cell Syst. 2016 Feb 24;2(2):112-121.

   Insert

   MEK1/2 (Map2k1, Map2k2 Mouse)
   

   Use

   Lentiviral

   Expression

   Mammalian

   Available Since

   July 12, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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3. FH1-PNGT#2-mCherry

   Plasmid

   #164099

   Purpose

   Fluorescent reporter for genetic tracing of proneural Glioblastoma cell-state.

   Depositor

   Gaetano Gargiulo

   Article

   Schmitt et al Cancer Discov. 2021 Mar;11(3):754-777. d

   Insert

   PNGT#2-mCherry
   

   Use

   Lentiviral and Synthetic Biology

   Available Since

   March 11, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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4. lentiCRISPR v2-sgNCKAP1-2

   Plasmid

   #210134

   Purpose

   knock out NCKAP1 in mammalian cells

   Depositor

   Boyi Gan

   Article

   Liu et al Nat Cell Biol. 2023 Mar;25(3):404-414. d

   Insert

   Nck-associated protein 1 (NCKAP1 Human)
   

   Use

   CRISPR

   Available Since

   Nov. 8, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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5. pSpCas9_BB_2A-GFP_MAPRE1-gRNA#2

   Plasmid

   #107727

   Purpose

   Knock out of EB1 in human cells by CRISPR/Cas9

   Depositor

   Torsten Wittmann

   Article

   van Haren et al Nat Cell Biol. 2018 Jan 29. pii: 10.1038

   Insert

   MAPRE1 gRNA #1 (targets Exon 1) (MAPRE1 Human)
   

   Expression

   Mammalian

   Promoter

   U6

   Available Since

   April 30, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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6. pLenti-SwitchON-sgCh2-2

   Plasmid

   #199637

   Purpose

   Tamoxifen-inducible expression of sgRNA control targeting intergenic region

   Depositor

   William Hahn

   Article

   So et al JCI Insight. 2022 Oct 10;7(19):e158755.

   Insert

   N/A
   

   Use

   Lentiviral

   Available Since

   June 2, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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7. SIN40C.TRE.dTomato.miR-125b-2.PGK.sfGFP.P2A.Tet3G

   Plasmid

   #169315

   Purpose

   Doxycycline-inducible expression of miR-125b-2 with dTomato as reporter fluorescent protein

   Depositor

   Jan-Henning Klusmann

   Article

   Alejo-Valle et al Blood. 2021 Sep 27. pii: S0006-4971(21)0

   Insert

   miR-125b-2 (MIR125B2 Human)
   

   Use

   Lentiviral

   Tags

   dTomato

   Promoter

   TRE

   Available Since

   Sept. 22, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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8. pcDNA5FRT/TO PP1gamma-2*Strep

   Plasmid

   #113506

   Purpose

   Expresses dual Strep-tagged PP1gamma in mammalian cells

   Depositor

   Hemmo Meyer

   Article

   Weith et al Mol Cell. 2018 Oct 11. pii: S1097-2765(1

   Insert

   PP1gamma (PPP1CC Human)
   

   Tags

   Strep-Strep

   Expression

   Mammalian

   Available Since

   Oct. 11, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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9. pLG1-puro-sgATL2-2

   Plasmid

   #109009

   Purpose

   CRISPRi knockdown of targeted gene (to be used with Addgene #102244 or other dCas9-KRAB constructs)

   Depositor

   Jacob Corn

   Article

   Liang et al J Cell Biol. 2018 Aug 24. pii: jcb.20180

   Insert

   ATL2-sgRNA #2 (ATL2 Human)
   

   Use

   Lentiviral

   Expression

   Mammalian

   Promoter

   mU6 promoter

   Available Since

   Aug. 22, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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10. FUS LC 4S->A#2

    Plasmid

    #226604

    Purpose

    4 serines to alanine at residue positions 70, 84, 89, 95

    Depositor

    Nicolas Fawzi

    Article

    Wake et al Nat Chem Biol. 2025 Jul;21(7):1076-1088.

    Insert

    FUS LC 4S->A#2 (FUS Human)
    

    Tags

    6His

    Expression

    Bacterial

    Mutation

    4 serines to alanine in sequence position subset …

    Promoter

    T7

    Available Since

    July 1, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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11. pLentiCRISPR v2-sgCBS-2

    Plasmid

    #230082

    Purpose

    Crispr knock out human CBS gene

    Depositor

    Xingguo Zhu

    Article

    Xi et al Commun Biol. 2025 Jan 6;8(1):15. doi: 10

    Insert

    CBS (CBS Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Available Since

    Jan. 10, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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12. pLentiCRISPR v2-sgL2HGDH-2

    Plasmid

    #230084

    Purpose

    Crispr knock out human L2HGDH gene

    Depositor

    Xingguo Zhu

    Article

    Xi et al Commun Biol. 2025 Jan 6;8(1):15. doi: 10

    Insert

    L2HGDH (L2HGDH Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Available Since

    Jan. 10, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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13. pcDNA3.1 TREK-2(S156C)

    Plasmid

    #224770

    Purpose

    In vitro transcription for Oocyte expression of 1 TREK-2(S156C)

    Depositor

    Dan Minor

    Article

    Deal et al Cell Chem Biol. 2024 Jul 18;31(7):1305-1

    Insert

    Potassium channel subfamily member 10 (Kcnk10 Mouse)
    

    Use

    In vitro transcription for oocyte expression

    Mutation

    S156C

    Promoter

    T7

    Available Since

    Sept. 13, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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14. lentiCRISPR v2-sgWAVE2-2

    Plasmid

    #210136

    Purpose

    knock out WAVE2 in mammalian cells

    Depositor

    Boyi Gan

    Article

    Liu et al Nat Cell Biol. 2023 Mar;25(3):404-414. d

    Insert

    Actin-binding protein WASF2 (WASF2 Human)
    

    Use

    CRISPR

    Available Since

    Nov. 8, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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15. pLV_dCas9-KRAB_sgSTK4i_#2 (PuroR)

    Plasmid

    #209774

    Purpose

    CRISPRi for STK4

    Depositor

    Michael Wehr

    Article

    Ma et al Cell Signal. 2024 Jan;113:110917. doi: 1

    Insert

    dCas9-KRAB, sgSTK4i (STK4 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Available Since

    Nov. 8, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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16. pXPR_003 sgINTS12 guide 2

    Plasmid

    #193607

    Purpose

    INTS12 knockout

    Depositor

    William Hahn

    Article

    Hagel et al Cancer Res. 2022 Dec 22:CAN-22-2245. doi

    Insert

    sgINTS12 guide 2 (INTS12 Human)
    

    Use

    Lentiviral

    Available Since

    Jan. 3, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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17. pX330A-Yap1-E1-#2

    Plasmid

    #171519

    Purpose

    deletion of a genomic locus in Yap1 gene

    Depositor

    Hans Schöler

    Article

    Kagiwada et al Development. 2021 Oct 15;148(20). pii: 2

    Insert

    Yap1 (Yap1 Mouse)
    

    Use

    CRISPR

    Expression

    Mammalian

    Available Since

    Nov. 9, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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18. SIN40C.SFFV.mTagBFP2.miR-125b-2

    Plasmid

    #169311

    Purpose

    Constitutive overexpression of miR-125b-2 with mTagBFP2 as a reporter fluorescent protein

    Depositor

    Jan-Henning Klusmann

    Article

    Alejo-Valle et al Blood. 2021 Sep 27. pii: S0006-4971(21)0

    Insert

    miR-125b-2 (MIR125B2 Human)
    

    Use

    Lentiviral

    Promoter

    SFFV

    Available Since

    Sept. 22, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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19. pcDNA-HisA-HOXC6-2

    Plasmid

    #110365

    Purpose

    Mammalian expression of HisA-tagged HOXC6-2

    Depositor

    Carlos Moreno

    Article

    Ramachandran et al Oncogene. 2005 Jan 6;24(1):188-98. doi:

    Insert

    HOXC6 (HOXC6 Human)
    

    Tags

    HIS

    Expression

    Mammalian

    Mutation

    short isoform

    Available Since

    March 10, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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20. PCRII apoA-IVb.2

    Plasmid

    #121904

    Purpose

    Plasmid for making zebrafish apoA-IVb.2 in situ probe

    Depositor

    Steven Farber

    Article

    Otis et al Dis Model Mech. 2015 Mar;8(3):295-309. d

    Insert

    Apoa4b.2 (apoa4b.2 Zebrafish)
    

    Use

    Unspecified

    Available Since

    May 3, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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