166,712 results

1. pAAV-CMV-FLEX-SaCas9-U6-sgSlc6a3

   Plasmid

   #159902

   Purpose

   Mutagenesis of Slc6a3

   Depositor

   Larry Zweifel

   Insert

   Slc6a3 (Slc6a3 Mouse)
   

   Use

   AAV, CRISPR, and Mouse Targeting

   Available Since

   Nov. 16, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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2. pME-ReaChR-citrine

   Plasmid

   #169045

   Purpose

   Middle entry vector for Gateway cloning that contains a ReaChR fused with citrine gene insert

   Depositor

   Paola Arlotta

   Article

   Harris et al Dev Cell. 2020 Jun 8;53(5):577-588.e7. d

   Insert

   ReaChR-citrine
   

   Use

   Gateway entry cloning vector

   Tags

   citrine

   Available Since

   Jan. 26, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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3. pBRIT HA/FLAG

   Plasmid

   #17519

   Depositor

   Michael Rudnicki

   Article

   McKinnell et al Nat Cell Biol. 2008 Jan . 10(1):77-84.

   Type

   Empty backbone

   Use

   Cre/Lox and Retroviral

   Tags

   FLAG and HA

   Expression

   Mammalian

   Available Since

   March 12, 2008

   Availability

   Academic Institutions and Nonprofits only

4. pET28a(His10-PD-1cyto)

   Plasmid

   #177896

   Purpose

   E coli expression of His10 tag fused to human PD-1 Intracellular Domain

   Depositor

   Ron Vale

   Article

   Hui et al Science. 2017 Mar 31;355(6332):1428-1433

   Insert

   PD-1 (aa 194-288 only) (PDCD1 Human)
   

   Tags

   10xHis-Thrombin cut site-T7 tag

   Expression

   Bacterial

   Promoter

   T7

   Available Since

   May 18, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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5. pDONR221_SLCO6A1

   Plasmid

   #132261

   Purpose

   Gateway entry clone with codon-optimized ORF sequence for subcloning into custom expression vectors

   Depositor

   RESOLUTE Consortium, Giulio Superti-Furga

   Article

   Superti-Furga et al Nat Rev Drug Discov. 2020 Jul;19(7):429-

   Insert

   SLCO6A1 (SLCO6A1 Human)
   

   Expression

   Mammalian

   Available Since

   Nov. 19, 2019

   Availability

   Industry, Academic Institutions, and Nonprofits

   

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6. pCDNA5/FRT-ChemoB-NAD

   Plasmid

   #193824

   Purpose

   CMV overexpression of ChemoB-NAD in mammalian cell lines

   Depositor

   Julien Hiblot

   Article

   Hellweg et al Nat Chem Biol. 2023 Jun 8. doi: 10.1038/

   Insert

   ChemoB-NAD
   

   Expression

   Mammalian

   Mutation

   EBFP2:N39Y, A206K, T225R; HT7: L271E

   Promoter

   CMV

   Available Since

   June 9, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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7. pDestTol2-actinb-kcnj13-EGFP

   Plasmid

   #164940

   Purpose

   Tol2 construct: actinb (actb2) promoter driven zebrafish kcnj13 fused with EGFP at the C terminus

   Depositor

   GuangJun Zhang

   Article

   Silic et al Genetics. 2020 Aug;215(4):1067-1084. doi

   Insert

   kcnj13 (kcnj13 Zebrafish)
   

   Use

   Tol2 transposon destination vector

   Tags

   EGFP

   Mutation

   Stop codon deleted

   Promoter

   actinb (actb2) promoter

   Available Since

   Feb. 25, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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8. TFORF1118

   Plasmid

   #141796

   Purpose

   Lentiviral vector for overexpressing transcription factor ORFs with unique 24-bp barcodes. Barcodes facilitate identification of transcription factors in pooled screens.

   Depositor

   Feng Zhang

   Article

   Joung et al Cell. 2023 Jan 5;186(1):209-229.e26. doi

   Insert

   SKP2 (SKP2 Human)
   

   Use

   Lentiviral

   Expression

   Mammalian

   Promoter

   EF1a

   Available Since

   Jan. 5, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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9. pT-Rex Dest30 dn-cHSF1

   Plasmid

   #134736

   Purpose

   Mammalian expression vector for inducible expression of a constitutively active dominant-negative HSF1

   Depositor

   Matthew D. Shoulders

   Article

   Moore et al ACS Chem Biol. 2016 Jan 15;11(1):200-10.

   Insert

   dn-cHSF1 (HSF1 Human)
   

   Expression

   Mammalian

   Mutation

   Deletion of amino acids 186-202, 379−529

   Promoter

   CMV/TO

   Available Since

   Jan. 18, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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10. pDONR223_PTEN_p.G129E

    Plasmid

    #81689

    Purpose

    Gateway Donor vector containing PTEN, part of the Target Accelerator Plasmid Collection.

    Depositor

    Jesse Boehm, William Hahn, David Root

    Article

    Kim et al Cancer Discov. 2016 Jul;6(7):714-26. doi

    Insert

    PTEN (PTEN Human)
    

    Use

    Gateway entry vector

    Mutation

    G129E

    Promoter

    None

    Available Since

    April 24, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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11. GARTA

    Plasmid

    #42388

    Purpose

    Bacterial expression for structure determination; may not be full ORF

    Depositor

    Nicola Burgess-Brown

    Insert

    GARTA (GART Human)
    

    Tags

    His6-TEV

    Expression

    Bacterial

    Mutation

    See Comments

    Available Since

    March 18, 2013

    Availability

    Academic Institutions and Nonprofits only

12. pNP3614 [pNP3613 - ISCro4 Recombinase (WT)]

    Plasmid

    #247265

    Purpose

    Express ISCro4 recombinase

    Depositor

    Patrick Hsu

    Article

    Perry et al Science. 2025 Sep 25:eadz0276. doi: 10.1

    Insert

    pNP3613 - ISCro4 Recombinase (WT)
    

    Expression

    Mammalian

    Available Since

    Dec. 2, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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13. SPLICa:ER-MT (High Affinity)

    Plasmid

    #247995

    Purpose

    Expresses the SPLICa reporter for ER-Mitochondria contacts and Calcium transients at the contact

    Depositor

    Tito Calì

    Article

    Yamaguchi et al Anal Chem. 2025 Sep 16;97(36):19848-1986

    Insert

    SPLICa ER-MT (h)
    

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    Nov. 18, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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14. pBOB-Mrap2-P2A-Mc4r-HA

    Plasmid

    #245991

    Purpose

    Stimultaneously express HA C-terminal tagged mouse MC4R and untagged MRAP2 protein using a P2A linker, transiently via transfection or stably via lentivirus-mediated infection in mammalian cells.

    Depositor

    Zhao Zhang

    Article

    Xun et al Science. 2025 Jun 5;388(6751):eadp3989.

    Insert

    Mrap2 and Mc4r (Mrap2, Mc4r Mouse)
    

    Use

    Lentiviral

    Tags

    HA

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    Oct. 8, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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15. pAAV-2xcHS4-cjSST-E2-CMVmini-3xHA-mScarlet3-miR-WPRE-hGHpA

    Plasmid

    #240048

    Purpose

    Expression of RFP in cortical SST interneurons in marmoset

    Depositor

    Guoping Feng

    Insert

    mScarlet3
    

    Use

    AAV

    Promoter

    CMVmini

    Available Since

    Aug. 13, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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16. pET15b-ALFA-TwinStrep

    Plasmid

    #240252

    Purpose

    IPTG-inducible plasmid with thermostable GFP (TGP) and Twin-Strep tags

    Depositor

    Olga Boudker, Krishna Reddy

    Article

    Reddy et al Nat Struct Mol Biol (2025).

    Type

    Empty backbone

    Tags

    10x HIS, ALFA, Thrombin, and Twin-Strep

    Expression

    Bacterial

    Promoter

    T7

    Available Since

    July 24, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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17. HiBiT-TP53(Y220C) Fusion Vector

    Plasmid

    #236914

    Purpose

    Express HiBiT-TP53(Y220C) in Mammalian Cells under a CMV promoter

    Depositor

    Promega Corporation

    Has Service

    DNA

    Insert

    TP53 (TP53 Human)
    

    Tags

    HiBiT

    Expression

    Mammalian

    Mutation

    Y220C

    Promoter

    CMV

    Available Since

    July 14, 2025

    Availability

    Industry, Academic Institutions, and Nonprofits

    

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18. TP53(Y220C)-HaloTag Fusion Vector

    Plasmid

    #236802

    Purpose

    Express TP53(Y220C)-HaloTag(R) Fusion Protein in Mammalian Cells under a CMV promoter

    Depositor

    Promega Corporation

    Has Service

    DNA

    Insert

    TP53(Y220C) (TP53 Human)
    

    Tags

    HaloTag (R)

    Expression

    Mammalian

    Mutation

    Y220C

    Promoter

    CMV

    Available Since

    July 14, 2025

    Availability

    Industry, Academic Institutions, and Nonprofits

    

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19. pIDTSmart-CMV-PLRS1

    Plasmid

    #217365

    Purpose

    Expression of previously developed E. coli leucyl aminoacyl-tRNA synthesis variant that is "polyspecific"

    Depositor

    Abhishek Chatterjee

    Article

    Huang et al ACS Synth Biol. 2024 Jul 19;13(7):2141-2

    Insert

    leucyl-tRNA synthetase polyspecific mutant
    

    Expression

    Mammalian

    Mutation

    M40I, T252A, Y499I, Y527A, H529G

    Promoter

    CMV

    Available Since

    July 1, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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20. pAAV-ITR-CMV-mCherry-1xU6-LtR-wt(TAG)

    Plasmid

    #217366

    Purpose

    Expresses E. coli leucine tRNA and a wild-type mCherry reporter; can be packaged into AAV

    Depositor

    Abhishek Chatterjee

    Article

    Huang et al ACS Synth Biol. 2024 Jul 19;13(7):2141-2

    Insert

    E. coli leucine tRNA for TAG suppression
    

    Use

    AAV

    Expression

    Mammalian

    Promoter

    U6

    Available Since

    July 1, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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